03 °“√»÷°…“‡ª√`¬∫‡∑`¬∫
Transcription
03 °“√»÷°…“‡ª√`¬∫‡∑`¬∫
°“√»÷°…“‡ª√’¬∫‡∑’¬∫§«“¡ ”‡√Á®„π°“√„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ¢â“ߴ⓬¥â«¬«‘∏’°“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ °—∫«‘∏’ª°μ‘ ‚™μ‘ π‘ Ÿß æ.∫.,* ¬Õ¥¬‘Ëß ªí≠® «— ¥‘Ï«ß»å æ.∫.,* πÿ™π“√∂ ∫ÿ≠®÷ߡߧ≈ æ.∫.,* æ—¥™“ ™—™«√—μπå æ.∫.* Abstract : Comparison of Success Rate in of Left Double-Lumen Tube Placement between Stylet Retained in DLT for Entire Intubating Procedure and Conventional Technique Nisoong C, M.D., FRCAT,* Punjasawadwong Y, M.D., FRCAT,* M.Med.Sc (Clinical Epidemiology),* Bunchungmongkol N, M.D., FRCAT,* Chatchawarat P, M.D.* *Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200. for 90o counterclockwise and advanced until resistance was encountered. The position of the DLT was confirmed by fiberoptic bronchoscopy. After surgery, the complications such as ruptured of tracheobronchial tree and pulmonary artery were observed. Results : The success rate of the placement of left-DLT to LMS in S-group was higher than C-group (97% vs 74%, p = 0.02). The success rate of the placement of DLT to correct position in S-group and C-group were 20% and 13%, respectively (p = 0.73). No severe complication was observed in both groups. Conclusion : Retaining the stylet in the left-DLT for the entire intubating procedure showed higher success rate of placement to left mainstem bronchus than conventional technique without severe complications. Background : The double-lumen tube (DLT) is the mainstay instrument of one-lung ventilation (OLV). Poor positioning of a DLT could affect oxygenation during OLV. Objective : To compare the success rate in the placement of left Rüsch-Endobronchial tube to left mainstem bronchus (LMS) in thoracic surgery between stylet retained in the DLT for the entire intubating procedure and conventional technique. Design : Randomized controlled trial. Materials and Methods : 60 ASA physical status I-III patients scheduled for elective surgical procedures requiring left-sided endobronchial intubations were included in this study. Patients were randomly assigned into two groups. In S-group (n = 30), the stylet was retained for the entire intubating procedure and in C-group (n = 30), the stylet was removed once the bronchial cuff passed through vocal cord. In both groups, the DLT was turned Keywords : Left double-lumen tube, retained stylet, left mainstem bronchus *¿“§«‘ ™ “«‘ — ≠ ≠’ «‘ ∑ ¬“ §≥–·æ∑¬»“ μ√å ¡À“«‘ ∑ ¬“≈— ¬ ‡™’ ¬ ß„À¡à ®.‡™’¬ß„À¡à 50200 Thai J Anesthesiology 2007 ; 33(3) : 161-8. 161 ∫∑π” °“√„À⬓√–ß—∫§«“¡√Ÿâ ÷° ”À√—∫°“√ºà“μ—¥∑√«ßÕ° ‡™àπ °“√ºà“μ—¥¡–‡√Áߪե‚¥¬°“√μ—¥ªÕ¥ÕÕ°∫“ß à«π °“√ ºà“μ—¥‡Õ“ªÕ¥ÕÕ°∑—Èߢâ“ß °“√ºà“μ—¥∑√«ßÕ°¥â«¬«‘∏’ àÕß°≈âÕß °“√ºà “ μ— ¥ ÀπÕß„π‡¬◊Ë Õ Àÿâ ¡ ªÕ¥ √«¡∂÷ ß °“√ºà “ μ— ¥ ¡–‡√Á ß À≈Õ¥Õ“À“√ ¡’§«“¡®”‡ªìπ∑’Ë®–μâÕß„™â‡∑§π‘§°“√¥¡¬“ ≈∫ ”À√—∫°“√ºà“μ—¥∑√«ßÕ° ‚¥¬°“√™à«¬À“¬„®¥â«¬«‘∏·’ ¬°ªÕ¥ (one-lung ventilation, OLV) ‡æ◊ËÕ„Àâ»—≈¬·æ∑¬å∑”°“√ºà“μ—¥ ‰¥â –¥«°¢÷πÈ ∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ (double-lumen tube, DLT) ®÷ ß ¡’ ∫ ∑∫“∑ ”À√— ∫ °“√™à « ¬À“¬„®¥â « ¬ OLV ‚¥¬π‘¬¡„™â DLT ¢â“ߴ⓬ ∂⓺ŸâªÉ«¬‰¡à¡’¢âÕÀâ“¡‡π◊ËÕß®“°¡’ Margin of 1 safety ¡“°°«à “ ·μà ‡ π◊Ë Õ ß®“° DLT ¡’ ¢ 𓥄À≠à ° «à “ ∑à Õ À≈Õ¥§Õ™π‘¥√Ÿ‡¥’¬« (Single lumen tube) §◊Õ ¡’‡ âπºà“»Ÿπ¬å°≈“ß¿“¬πÕ°¡“°°«à“ ·≈–¡’§«“¡¬“«¡“°°«à“ √«¡∑—Èß ¬—ß¡’ à«π‚§âß∑’˧ßμ—«¡“°°«à“ (fixed shape)2 ®÷ß∑”„Àâ°“√„ à È “√„ à DLT ¡’§«“¡¬“°°«à“∑àÕÀ≈Õ¥§Õ™π‘¥√Ÿ‡¥’¬« πÕ°®“°π’° DLT ¢â“ߴ⓬μâÕß„À≥âμ”·Àπàß∑’ˇÀ¡“– ¡‡æ◊ËÕ„Àâ “¡“√∂∑” OLV ‰¥âÕ¬à“ß¡’ª√– ‘∑∏‘¿“æ·≈–≈¥¿“«–·∑√°´âÕπ®“°°“√ ™à«¬À“¬„®¥â«¬ OLV ‡™àπ ÕÕ°´‘‡®π„π°√–· ‡≈◊Õ¥μË” §“√å∫Õπ‰¥ÕÕ°‰´§å„π°√–· ‡≈◊Õ¥ Ÿß ªÕ¥·ø∫ √«¡∂÷߉¡à “¡“√∂ ∑”°“√™à«¬À“¬„®¥â«¬ OLV ‰¥â ”‡√Á® ∑”„À⇪ìπÕÿª √√§ ”À√—∫°“√ºà“μ—¥ ´÷Ëß à«π„À≠à¡’ “‡Àμÿ¡“®“°μ”·ÀπàߢÕß 3 DLT ‰¡à‡À¡“– ¡ ¥—ßπ—Èπ°“√„ à DLT ¢â“ߴ⓬„Àâ ”‡√Á®®÷ß¡’ §«“¡®”‡ªìπ ”À√—∫°“√∑”°“√™à«¬À“¬„®¥â«¬ OLV „πÕ¥’μ„™â«‘∏’°“√øí߇ ’¬ß≈¡ºà“πªÕ¥ ‡æ◊ËÕ¬◊π¬—π μ”·ÀπàߢÕß DLT ·μà¡’°“√»÷°…“æ∫«à“ °“√øíߪե‡æ’¬ß Õ¬à“߇¥’¬«‰¡àπà“‡™◊ËÕ∂◊Õ4-7 ®÷߉¥â¡’°“√π”°≈âÕß àÕßÀ≈Õ¥≈¡ ™π‘¥„¬·°â«π”· ß (fiberoptic bronchoscope, FOB) ¡“„™â ‡æ◊ËÕ¬◊π¬—πμ”·Àπàß∑’ˇÀ¡“– ¡4-6,8-9 ·≈–æ∫«à“À≈—ß®“°„™â FOB ‡æ◊ËÕμ√«® Õ∫μ”·Àπàß„π°“√„ à DLTs ¢â“ߴ⓬™π‘¥ æ’«’´’ æ∫«à“„ à‰¥â„πμ”·Àπàß∑’ˉ¡à‡À¡“– ¡∂÷ß 48-78% ‚¥¬ æ∫«à“ μ”·Àπàß„π°“√„ à DLT ¢â“ߴ⓬∑’ˉ¡à‡À¡“– ¡¡’ 3 ·∫∫§◊Õ „ à‡¢â“À≈Õ¥≈¡¢â“ߢ«“ (Incorrect bronchus) „ à ‡¢â“À≈Õ¥≈¡´â“¬ (Correct bronchus) ·μàμ◊ÈπÀ√◊Õ≈÷°‡°‘π‰ª10 ‚¥¬æ∫°“√„ à‡¢â“À≈Õ¥≈¡¢«“¥â«¬«‘∏’ª°μ‘ (Conventional 6 technique) √âÕ¬≈– 20 ´÷ßË Õ“®‡°‘¥®“°≈—°…≥–∑“ß°“¬«‘¿“§ ∑’Ë·μ°μà“ß°—π¢ÕßÀ≈Õ¥≈¡´â“¬·≈–¢«“11 §◊Õ °“√∑’ËÀ≈Õ¥≈¡ ¢«“∑”¡ÿ¡°—∫·π«°÷Ëß°≈“ߢÕß∑àÕÀ≈Õ¥§ÕπâÕ¬°«à“À≈Õ¥≈¡ 162 «‘ —≠≠’ “√ ´â“¬ §◊Õ 25 Õß»“·≈– 45 Õß»“μ“¡≈”¥—∫ √à«¡°—∫¢π“¥¢Õß À≈Õ¥≈¡¢«“„À≠à°«à“À≈Õ¥≈¡´â“¬§◊Õ 16 ¡¡. ·≈– 13 ¡¡. μ“¡≈”¥—∫ ®÷ß∑”„Àâ¡’‚Õ°“ „ à DLT ¢â“ߴ⓬‡¢â“À≈Õ¥≈¡ ¢«“‰¥â ·°π≈«¥∑’Ë„ à¡“„π Bronchial lumen ¢Õß DLT ™à«¬∑”„Àâ√Ÿª√à“ß√«¡∂÷ß§«“¡‚§âßμ—«¢Õß DLT §ß√Ÿª ´÷Ëß„π §”·π–π”®“°‚√ßß“π∑’˺≈‘μ DLT ™π‘¥π’È„Àâ¥÷ß·°π≈«¥ÕÕ° ∂⓪≈“¬¢Õß DLT ºà“π‡ âπ‡ ’¬ß ‚¥¬„Àâ‡Àμÿº≈μ“¡∑ƒ…Æ’«à“ ®–≈¥°“√∫“¥‡®Á∫¢Õ߇¬◊ËÕ∫ÿÀ≈Õ¥§Õ·≈–À≈Õ¥≈¡ ·μà°Á¬—ß ‰¡à¡’°“√√“¬ß“π∑’Ë π—∫ πÿπ·π«§‘¥π’È √«¡∂÷ß®“°°“√»÷°…“ ¢Õß Leiberman D. ·≈–§≥–12 æ∫«à“°“√„ à DLT ™π‘¥æ’«’´’ ¢â“ߴ⓬ ‚¥¬«‘∏’°“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ‡æ‘Ë¡ §«“¡ ”‡√Á®„π°“√„ à DLT „À⇢â“À≈Õ¥≈¡´â“¬‡¡◊ËÕ‡ª√’¬∫ ‡∑’¬∫°—∫«‘∏’ª°μ‘ ‚¥¬∑’ˉ¡à‰¥â‡æ‘Ë¡¿“«–·∑√°´âÕπ®“°°“√„ à DLT ¥â«¬«‘∏’π’È ·μà°“√»÷°…“„π‡√◊ËÕß°“√„ à DLT ¥â«¬«‘∏’π’È¡’ ‡æ’¬ß°“√»÷°…“‡¥’¬«‡∑à“π—Èπ ·≈–»÷°…“„πª√–™“°√ª√–‡∑» ·§π“¥“ ‚¥¬¬—߉¡à¡’°“√»÷°…“„πª√–™“°√‰∑¬ §≥–ºŸâ«‘®—¬®÷ß μâÕß°“√»÷°…“„π§π‰∑¬«à“°“√„ à·°π≈«¥μ≈Õ¥°“√„ à DLT ¢â“ߴ⓬™à«¬‡æ‘Ë¡§«“¡ ”‡√Á®„π°“√„ à DLT „À⇢â“À≈Õ¥≈¡ ´â“¬¡“°°«à“°“√„ à¥â«¬«‘∏’ª°μ‘À√◊Õ‰¡à «—μ∂ÿª√– ß§åß“π«‘®—¬ 1. ‡æ◊ËÕ‡ª√’¬∫‡∑’¬∫§«“¡ ”‡√Á®„π°“√„ à DLT ¢â“ß ´â“¬„À⇢â“À≈Õ¥≈¡´â“¬„πºŸâªÉ«¬∑’ˇ¢â“√—∫°“√ºà“μ—¥∑√«ßÕ° √–À«à“ß«‘∏’°“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ°—∫«‘∏’ª°μ‘ 2. ‡æ◊Ë Õ ‡ª√’ ¬ ∫‡∑’ ¬ ∫§«“¡ ”‡√Á ® „π°“√„ à DLT ¢â“ߴ⓬„À≥âμ”·Àπàß∑’ˇÀ¡“– ¡„πºŸâªÉ«¬∑’ˇ¢â“√—∫°“√ºà“μ—¥ ∑√«ßÕ°√–À«à“ß«‘∏’°“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ °—∫«‘∏’ª°μ‘ 3. ‡æ◊Ë Õ ‡ª√’ ¬ ∫‡∑’ ¬ ∫¿“«–·∑√°´â Õ π®“°°“√„ à DLT ¢â“ߴ⓬„πºŸâªÉ«¬∑’ˇ¢â“√—∫°“√ºà“μ—¥∑√«ßÕ°√–À«à“ß«‘∏’ °“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ°—∫«‘∏’ª°μ‘ «‘∏’°“√»÷°…“ °“√»÷°…“§√—Èßπ’ȉ¥âºà“π°“√æ‘®“√≥“·≈–‰¥â√—∫§«“¡ ‡ÀÁπ™Õ∫®“°§≥–°√√¡°“√®√‘¬∏√√¡°“√«‘®—¬„π¡πÿ…¬å¢Õß ·æ∑¬»“ μ√å ¡À“«‘∑¬“≈—¬‡™’¬ß„À¡à ·≈–‰¥â√—∫§«“¡¬‘π¬Õ¡ ®“°ºŸâªÉ«¬„π°“√‡¢â“√à«¡«‘®—¬‚¥¬≈ß™◊ËÕ„π„∫Õπÿ≠“μ„Àâ∑”°“√ »÷°…“ ‚¥¬‰¥â∑”°“√»÷°…“·∫∫ Randomized controlled trial ªï∑’Ë 33 ©∫—∫∑’Ë 3 °√°Æ“§¡-°—𬓬π 2550 „πºŸªâ «É ¬∑’¡Ë “√—∫°“√ºà“μ—¥∑√«ßÕ°™π‘¥‰¡à‡√àߥà«π ¢Õß‚√ßæ¬“∫“≈¡À“√“™π§√ ‡™’¬ß„À¡à ®”π«π 60 §π ´÷Ëß¡’§ÿ≥ ¡∫—μ‘ μ“¡ Inclusion ·≈– Exclusion criteria ¥—ßμàÕ‰ªπ’È Inclusion criteria 1. ASA class I-III 2. ‡¢â “ √— ∫ °“√ºà “ μ— ¥ ∑√«ßÕ°™π‘ ¥ ‰¡à ‡ √à ß ¥à « π ∑’Ë ®”‡ªìπμâÕß„ à DLT ¢â“ߴ⓬ Exclusion criteria 1. ºŸâªÉ«¬∑’Ë¡’¢âÕÀâ“¡„π°“√„ à DLT ¢â“ߴ⓬13 ‡™àπ ¡’√Õ¬‚√§„π∫√‘‡«≥∑’Ë DLT ºà“π, ¡’°“√μ’∫·§∫¢ÕßÀ≈Õ¥§Õ (Tracheal stenosis) À√◊Õ∑àÕÀ≈Õ¥≈¡¢â“ߴ⓬ (Left main bronchus stenosis) ·≈–≈—°…≥–√Ÿª√à“ߢÕß∫√‘‡«≥À≈Õ¥§Õ∑’Ë ·¬°‡ªìπÀ≈Õ¥≈¡¢â“ߴ⓬·≈–¢â“ߢ«“∑’˺‘¥ª°μ‘ (distorted carinal architecture) í À“„π°“√„ à∑Õà ™à«¬À“¬„® â «É ¬∑’§Ë “¥«à“®–¡’ª≠ 2. ºŸª ≈”∫“° ‰¥â·°à ºŸâªÉ«¬∑’Ë¡’ª√–«—μ‘ºà“μ—¥∫√‘‡«≥§Õ ¡’ª√–«—μ‘ ‰¥â√∫— √—ß ’√°— …“∫√‘‡«≥§Õ√à«¡°—∫¡’ª√–«—μ°‘ “√„ à∑Õà ™à«¬À“¬„® ¬“° ·≈–°√–¥Ÿ° —πÀ≈—ß à«π§Õ‰¥â√—∫∫“¥‡®Á∫ μ√«®√à“ß°“¬ æ∫«à“ Mallampati classification III-IV13, Inter-incisor gap < 3 ´¡. Thyromental distance < 6 ´¡. ·≈–¡’°“√®”°—¥ ¢Õß°“√°â¡·≈–·Àßπ¢âÕμàÕ atlanto-occipital ºŸâªÉ«¬∑—ÈßÀ¡¥ 60 §π ∂Ÿ°·∫àßÕÕ°‡ªìπ 2 °≈ÿà¡ Ê ≈– 30 §π ‚¥¬°“√ ÿà¡·≈–„™â sealed envelope ”À√—∫ allocation concealment ‚¥¬ C-group ‡ªìπ°≈ÿà¡§«∫§ÿ¡ ‰¥â√—∫ °“√„ à DLT ¢â“ߴ⓬¥â«¬«‘∏’ª°μ‘ §◊Õ °“√„ à DLT ‚¥¬ ¥÷ß·°π≈«¥ÕÕ°‡¡◊ËÕ bronchial cuff ¢Õß DLT ºà“π‡ âπ‡ ’¬ß ·≈â « À≈— ß ®“°π—È π À¡ÿ π DLT ∑«π‡¢Á¡π“Ãî°“ 90o ·≈â«¥—π 14 DLT ‡¢â“‰ª®π√Ÿâ ÷°«à“¡’·√ßμâ“π ·≈â«®÷ßÀ¬ÿ¥ à«π S-group ‡ªìπ°≈ÿà¡»÷°…“‰¥â√—∫°“√„ à DLT ¢â“ߴ⓬‡À¡◊Õπ«‘∏’ª°μ‘ ·μà ®–¥÷ß·°π≈«¥ÕÕ°°ÁμàÕ‡¡◊ËÕ„ à DLT ‡ √Á® ºŸªâ «É ¬‰¥â√∫— ÕÕ°´‘‡®π 100% ºà“πÀπâ“°“°π“π 3-5 π“∑’ ®“°π—Èππ” ≈∫¥â«¬ Thiopentone 3-5 mg/kg ∫√‘À“√ ¬“∑“ßÀ≈Õ¥‡≈◊Õ¥¥” À≈—ß®“°π—Èπ„À⬓À¬àÕπ°≈â“¡‡π◊ÈÕ°≈ÿà¡ nondepolarizing §◊Õ Vecuronium 0.1-0.2 mg/kg ∫√‘À“√ ¬“∑“ßÀ≈Õ¥‡≈◊Õ¥¥” „™â‡«≈“ª√–¡“≥ 3 π“∑’ „π°“√™à«¬ À“¬„®ºà“πÀπâ“°“°·≈–Õ“®„™âÕÿª°√≥凪î¥∑“߇¥‘πÀ“¬„®∑“ß ª“°À“°¡’ § «“¡®”‡ªì π À≈— ß ®“°π—È π „ à DLT ‚¥¬·æ∑¬å ª√–®”∫â“πªï∑’Ë 2 À√◊Õ 3 À√◊ÕÕ“®“√¬å·æ∑¬å ‚¥¬‡≈◊Õ°¢π“¥ (French number) μ“¡«‘∏’¢Õß Hannallah15 μ“¡ Appendix Vol. 33, No. 3, July-September 2007 1 À≈—ß®“°„ à DLT ·≈â« «‘ —≠≠’·æ∑¬å∑’Ë¡’§«“¡™”π“≠„π °“√„™â FOB ´÷Ë߉¡à∑√“∫«à“ºŸâªÉ«¬Õ¬Ÿà„π°≈ÿà¡„¥„™â FOB μ√«® Õ∫μ”·ÀπàߢÕß DLT «à“Õ¬Ÿ„à πμ”·Àπàß∂Ÿ°μâÕß·≈–‡À¡“– ¡ À√◊Õ‰¡à ‚¥¬°“√ àÕß FOB ºà“π‡¢â“‰ª„π tracheal lumen ®π ‡ÀÁπ carina ∂ⓇÀÁπ bronchial lumen ‡¢â“‰ª„πÀ≈Õ¥≈¡´â“¬ ·≈–‡ÀÁπ à«π∫π ÿ¥¢Õß bronchial cuff ´÷ßË ¡’ ø’ “Ñ Õ¬Ÿ„à πÀ≈Õ¥≈¡ ´â“¬·≈–Õ¬Ÿà∫√‘‡«≥„μâμàÕ carina ‡≈Á°πâÕ¬ (just below carina) ∂◊Õ«à“μ”·Àπàß∂Ÿ°μâÕß À√◊Õ∂â“¡Õ߉¡à‡ÀÁπ bronchial cuff · ¥ß«à“‡¢â“‰ª„πÀ≈Õ¥≈¡´â“¬≈÷°‡°‘π‰ª ·≈–∂â“¡Õ߇ÀÁπ bronchial cuff Õ¬Ÿà∫π carina ∂◊Õ«à“μ◊Èπ‡°‘π‰ª „π™à«ß‡«≈“√–À«à“ߺà“μ—¥¡’°“√‡ΩÑ“μ‘¥μ“¡≈—°…≥– ∑“ß§≈‘π‘°¢ÕߺŸâªÉ«¬«à“¡’¿“«–·∑√°´âÕπ∑’Ë√ÿπ·√ß®“°°“√„ à DLT §◊Õ ¡’°“√©’°¢“¥¢ÕßÀ≈Õ¥§ÕÀ√◊ÕÀ≈Õ¥≈¡ À√◊Õ¡’°“√ ©’°¢“¥¢ÕßÀ≈Õ¥‡≈◊Õ¥ Palmonary À√◊Õ‰¡à √–À«à“ß°“√„ à DLT ºŸâªÉ«¬∑ÿ°§π‰¥â√—∫°“√‡ΩÑ“√–«—ß √–¥—∫§«“¡Õ‘Ë¡μ—«¢ÕßÕÕ°´‘‡®π„π‡≈◊Õ¥·¥ß¥â«¬ Pulse oximeter „ÀâÕ¬Ÿà„π™à«ß 94-100% §«“¡¥—π‚≈À‘μ·≈–Õ—μ√“°“√ ‡μâπ¢ÕßÀ—«„®‰¡à„Àâ‡æ‘Ë¡¢÷ÈπÀ√◊Õ≈¥≈ß¡“°°«à“ 20% ®“°√–¥—∫ ª°μ‘¢ÕߺŸâªÉ«¬ ·≈–§≈◊Ëπ‰øøÑ“À—«„®„ÀâÕ¬Ÿà„π‡°≥±åª°μ‘ ∑”°“√∫—π∑÷°¢âÕ¡Ÿ≈∑—Ë«‰ª¢ÕߺŸâªÉ«¬ μ”·ÀπàߢÕß DLT ∑’Ë„ à„π§√—Èß·√° ‚¥¬·∫à߇ªìπ„ à‰¥âμ”·Àπà߇À¡“– ¡ À√◊Õ„ à‡¢â“À≈Õ¥≈¡¢â“ߢ«“ ‡¢â“À≈Õ¥≈¡¢â“ߴ⓬·μàμ◊ÈπÀ√◊Õ ≈÷°‡°‘π‰ª À√◊Õ„ à‡¢â“À≈Õ¥Õ“À“√ ®”π«π§√—Èß„π°“√„ à DLT ®π ”‡√Á® ºŸâ„ à DLT „π§√—Èß·√° √–¬–‡«≈“∑’Ë„™â„π°“√„ à DLT ®π ”‡√Á® (μ—Èß·μà‡√‘Ë¡„ à Laryngoscope ®π∂÷ß„ à DLT ‡¢â“ À≈Õ¥≈¡´â“¬‰¥âμ”·Àπà߇À¡“– ¡‚¥¬°“√¬◊π¬—π®“° FOB) ·≈–¿“«–·∑√°´âÕπ∑’Ë√ÿπ·√ß®“°°“√„ à DLT ¢π“¥μ—«Õ¬à“ß §”π«≥¢π“¥μ— « Õ¬à “ ß®“°Õ— μ √“¢Õß°“√„ à DLT ¢â“ߴ⓬‡¢â“À≈Õ¥≈¡¢«“ ®“°°“√»÷°…“∑’ˇ§¬¡’¡“°àÕπ4 ´÷Ëß æ∫√âÕ¬≈– 20 °”Àπ¥ α = 0.05 ·≈– β = 0.2 ·≈–°”Àπ¥ «à“°“√„ à·°π≈«¥μ≈Õ¥°“√„ à DLT “¡“√∂≈¥Õ—μ√“¢Õß °“√„ à‡¢â“À≈Õ¥≈¡¢«“√âÕ¬≈– 50 „™â‚ª√·°√¡ STATA „π °“√§”π«≥À“¢π“¥μ—«Õ¬à“߉¥â 30 §πμàÕ°≈ÿà¡ °“√«‘‡§√“–Àå∑“ß ∂‘μ‘ «‘‡§√“–ÀåÀ“§«“¡·μ°μà“ߢÕß§à“‡©≈’ˬ¢ÕߢâÕ¡Ÿ≈ æ◊Èπ∞“πºŸâªÉ«¬√–À«à“ß°≈ÿà¡ ª√–°Õ∫¥â«¬ Õ“¬ÿ πÈ”Àπ—° à«π Thai Journal of Anesthesiology 163 Ÿß ·≈–√–¬–‡«≈“∑’Ë„™â„π°“√„ à DLT ®π ”‡√Á® ¥â«¬ t-test for independent group «‘‡§√“–ÀåÀ“§«“¡·μ°μà“ߢÕߢâÕ¡Ÿ≈ æ◊Èπ∞“πÕ◊Ëπ Ê √–À«à“ß°≈ÿà¡ ª√–°Õ∫¥â«¬ ‡æ», ASA physical status, Mallampati classification, laryngoscopic view ¢â“ߴ⓬ ·≈–ª√–‡¿∑¢ÕߺŸâ„ à DLT ¥â«¬ Chi-squre ·≈– Fisher’s exact test À“§«“¡·μ°μà“ߢÕß §«“¡ ”‡√Á ® ¢Õß°“√„ à DLT ¢â “ ß´â “ ¬‡¢â “ À≈Õ¥≈¡´â “ ¬ √–À«à“ß°≈ÿࡥ⫬ Fisher’s exact test «‘‡§√“–Àå‚¥¬„™â‚ª√·°√¡ SPSS version 13.0 ‚¥¬ p < 0.05 ∂◊Õ«à“¡’§«“¡·μ°μà“ß°—πÕ¬à“ß¡’π—¬ ”§—≠∑“ß ∂‘μ‘ ¢π“¥¢Õß DLT º≈°“√»÷°…“ ºŸâªÉ«¬∑’Ë∑”°“√»÷°…“∑—ÈßÀ¡¥¡’ 60 §π ∑—Èß Õß°≈ÿà¡ ‰¡à¡’§«“¡·μ°μà“ß°—πÕ¬à“ß¡’π—¬ ”§—≠∑“ß ∂‘μ‘„π¥â“πÕ“¬ÿ ‡æ» πÈ”Àπ—° à«π Ÿß ASA physical status ™π‘¥°“√ºà“μ—¥ Mallampati classification ¥—ß· ¥ß„πμ“√“ß∑’Ë 1 ¢π“¥¢Õß DLT √–¥—∫ª√– ∫°“√≥å¢ÕߺŸâ„ à DLT laryngoscopic view ®”π«π§√—Èß·≈–√–¬–‡«≈“∑’Ë„ à DLT ®π ”‡√Á® ¥—ß· ¥ß‰«â μ“¡μ“√“ß∑’Ë 2 §«“¡ ”‡√Á®¢Õß°“√„ à DLT §”π«≥®“° √âÕ¬≈–¢ÕߺŸâªÉ«¬∑’Ë “¡“√∂„ à DLT ‡¢â“À≈Õ¥≈¡´â“¬ ”‡√Á® „π§√—Èß·√°æ∫«à“ S-group ¡’§«“¡ ”‡√Á®¡“°°«à“ C-group Õ¬à“ß¡’π—¬ ”§—≠∑“ß ∂‘μ‘ (97% vs 74%, p = 0.026) ¥—ß · ¥ß‰«âμ“¡μ“√“ß∑’Ë 3 ·μàæ∫«à“°“√„ à DLT „À≥âμ”·Àπàß ∑’ˇÀ¡“– ¡°—π√–À«à“ß S-group °—∫ C-group §◊Õ (20% vs 13%, p = 0.733) ¥—ß· ¥ß‰«âμ“¡μ“√“ß∑’Ë 4 °“√»÷°…“§√—ßÈ π’‰È ¡àæ∫¿“«–§«“¡Õ‘¡Ë μ—«¢ÕßÕÕ°´‘‡®π „π°√–· ‡≈◊Õ¥μË”°«à“ 90% „π√–À«à“ß°“√„ à DLT ·≈–°“√ „™â FOB ¬◊π¬—πμ”·ÀπàߢÕß DLT „π√–À«à“ß°“√™à«¬À“¬„® ¥â«¬ OLV ‚¥¬„™â√–¥—∫§«“¡‡¢â¡¢âπ¢ÕßÕÕ°´‘‡®π√–À«à“ß 60-100% æ∫«à“§«“¡Õ‘Ë¡μ—«¢ÕßÕÕ°´‘‡®πμË”°«à“ 90% „π C-group ®”π«π 1 √“¬ ®÷ߙ૬À“¬„®¥â«¬ªÕ¥∑—Èß Õߢâ“ß √–¥—∫§«“¡Õ‘Ë¡μ—«¢ÕßÕÕ°´‘‡®π‡æ‘Ë¡¢÷Èπ‡ªìπ 100% ·≈–‰¥âπ” FOB ¬◊π¬—πμ”·ÀπàߢÕß DLT ´È” æ∫«à“‰¡à¡’°“√‡ª≈’Ë¬π ·ª≈ß ®÷߉¥â„™â continuous positive airway pressure (CPAP) „πªÕ¥∑’Ë∂Ÿ°¬ÿ∫·ø∫ ∑”„Àâ “¡“√∂™à«¬À“¬„®¥â«¬ OLV ‰¥â ‚¥¬‰¡à¡’¿“«–ÕÕ°´‘‡®π„π°√–· ‡≈◊Õ¥μË” ·≈–‰¡à√∫°«π°“√ ºà“μ—¥ „π°“√»÷°…“§√—Èßπ’ȉ¡àæ∫ºŸâªÉ«¬∑’Ë¡’¿“«–·∑√°´âÕπ∑’Ë √ÿπ·√ß®“°°“√„ à DLT Table 1 Patient’s data S-group (n = 30) C-group (n = 30) p-value 49.1 ± 16.8 47.7 ± 14.9 0.333 13 (43%) 12 (40%) 1.000 Weight (kg) 56.4 ± 10.7 52.6 ± 8.5 1.534 Height (cm) 163.2 ± 8.6 160.5 ± 8.5 1.222 Patient’s data Age (year) Sex Male 0.210 ASA physical status 1 17 (56%) 11 (37%) 2 10 (33%) 17 (56%) 3 3 (9%) 2 (7%) 1.000 Mallampati Classification 164 1 10 (33%) 11 (37%) 2 20 (67%) 19 (63%) «‘ —≠≠’ “√ ªï∑’Ë 33 ©∫—∫∑’Ë 3 °√°Æ“§¡-°—𬓬π 2550 Table 2 Data about DLT intubation S-group (n = 30) Data C-group (n = 30) p-value 0.510 ¢π“¥ DLT Fr35 10 (33%) 12 (40%) Fr37 9 (30%) 8 (27%) Fr39 11 (37%) 10 (33%) 19/9/2 (63%/30%/7%) 15/11/4 (50%/37%/13%) ºŸâ„ à DLT (R2/R3/Staff) 0.170 1.670 Laryngoscopic view grade 1 24 (80%) 21 (70%) grade 2 6 (20%) 9 (30%) 0.080 Number of intubation (§√—Èß) 1-2 30 (100%) 26 (86%) 3-4 0 (0%) 4 (14%) 190.8 ± 88.1 207.4 ± 88.7 0.460 S-group (n = 30) C-group (n = 30) P-value 29 (97%) 22 (74%) 0.026 1 (3%) 8 (26%) Duration of intubation (seconds) Table 3 Success rate DLT Position of left-DLT Correct bronchus (LMS)* Incorrect bronchus (RMS) or esophagus Table 4 Position of left-DLT in Left mainstem Bronchus (%) S-group (n = 29) C-group (n = 22) P-value Proper position 6 (20%) 4 (13%) 0.733 Out too far 3 (10%) 2 (7%) 20 (67%) 16 (54%) Left mainstem bronchus In too far «‘®“√≥å °“√„ à DLT „À≥âμ”·Àπàß∑’ˇÀ¡“– ¡‡æ◊ËÕ°“√™à«¬ À“¬„®¥â«¬ OLV ¡’§«“¡ ”§—≠„Àâ°“√√–ß—∫§«“¡√Ÿâ ÷° ”À√—∫ °“√ºà“μ—¥∑√«ßÕ° ‡π◊ËÕß®“°æ∫«à“ “‡Àμÿ∑’Ë∑”„À⇰‘¥¿“«– ÕÕ°´‘‡®π„π°√–· ‡≈◊Õ¥μË”√–À«à“ߙ૬À“¬„®¥â«¬ OLV §◊Õ Vol. 33, No. 3, July-September 2007 μ”·ÀπàߢÕß DLT ‰¡à‡À¡“– ¡ ´÷Ëßæ∫∫àÕ¬°«à“ “‡Àμÿ®“° ‚√§ªÕ¥‡¥‘¡¢ÕߺŸâªÉ«¬16 °“√»÷°…“§√—Èßπ’Èæ∫«à“ §«“¡ ”‡√Á®¢Õß°“√„ à DLT ™π‘¥ left Rüsch-Endobronchial tube ‡¢â“À≈Õ¥≈¡´â“¬¥â«¬ «‘∏’°“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ Ÿß°«à“«‘∏’ª°μ‘ ´÷Ëß Thai Journal of Anesthesiology 165 ‡À¡◊Õπ°—∫°“√»÷°…“¢Õß Leiberman D. ·≈–§≥–12 ∑’Ë„™â DLT ™π‘¥ left BronchoCathTM Endobronchial tube ‚¥¬ §«“¡ ”‡√Á®∑’‡Ë æ‘¡Ë ¢÷πÈ Õ“®‡°‘¥®“°°“√∑’·Ë °π≈«¥∑”„Àâ§«“¡‚§âß ¢Õß DLT §ß√ŸªÕ¬Ÿà¢≥–„ ஓ°À≈Õ¥§Õ‡¢â“ ŸàÀ≈Õ¥≈¡´â“¬ ®÷ß∑”„Àâ “¡“√∂„ àÀ≈Õ¥≈¡´â“¬‰¥â ”‡√Á®¡“°¢÷Èπ „π°“√»÷°…“§√—Èßπ’È æ∫§«“¡≈⡇À≈«„π°“√„ à DLT ¥â«¬«‘∏ª’ °μ‘√Õâ ¬≈– 26 „°≈⇧’¬ß°—∫°“√»÷°…“¢Õß Leiberman 12 D. ·≈–§≥– ∑’Ëæ∫°“√„ à‡¢â“À≈Õ¥≈¡¢â“ߢ«“√âÕ¬≈– 23 ¥â«¬«‘∏’ª°μ‘ ´÷Ëß„°≈⇧’¬ß°—∫∑’Ë Smith ·≈–§≥–4 ‰¥â√“¬ß“π‰«â §◊Õ√âÕ¬≈– 20 §«“¡≈⡇À≈«¥—ß°≈à“«Õ“®‡°‘¥®“°°“√¥÷ß·°π ≈«¥ÕÕ°¢≥–∑’Ë Bronchial cuff ºà“π‡ âπ‡ ’¬ß°àÕπ∑’Ë®–¥—π DLT ‡¢â“À≈Õ¥≈¡ ´÷ËßÕ“®‡°‘¥°“√∫‘¥‡∫’Ȭ«¢Õß DLT ·≈–∑” „Àâ Bronchial angle ‡ ’¬‰ª DLT ®÷߇¢â“ ŸàÀ≈Õ¥≈¡¢«“·∑π πÕ°®“°π’È DLT Õ“®‡§≈◊ËÕπÀ≈ÿ¥ÕÕ°¡“Õ¬Ÿà„πÀ≈Õ¥Õ“À“√‰¥â ®“°°“√¥÷ß·°π≈«¥∑’Ë¡’§«“¡·¢ÁßÕÕ° ‚¥¬‡©æ“–∂â“¡’°“√„ à DLT ∑’Ë≈÷°‰¡àæÕÀ√◊Õ„ à “√À≈àÕ≈◊Ëπ∑’Ë·°π≈«¥πâÕ¬‡°‘π‰ª ∑” „Àâ¥÷ß·°π≈«¥ÕÕ°‰¥â¬“° ·¡â«“à °“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑Õà À≈Õ¥§Õ®–™à«¬ ‡æ‘¡Ë §«“¡ ”‡√Á®„π°“√„ à DLT ¢â“ߴ⓬‡¢â“ ŸÀà ≈Õ¥≈¡´â“¬¡“° °«à“¢â“ߢ«“ ·μà°Áæ∫°“√„ à DLT „À≥âμ”·Àπàß∑’ˇÀ¡“– ¡ πâÕ¬„π∑—Èß Õß°≈ÿà¡ ´÷ËßÕ“®‡°‘¥®“°§«“¡™”π“≠¢ÕߺŸâ„ à ‡π◊ËÕß ®“°∑—Èß Õß°≈ÿà¡„ à‚¥¬·æ∑¬åª√–®”∫â“πªï∑’Ë 2 ·≈–ªï∑’Ë 3 ‡ªìπ à«π„À≠à ¥—ßπ—Èπ°“√„ à·°π≈«¥‰«âμ≈Õ¥¢≥–„ à DLT ®÷ߙ૬ „Àâ„ à‡¢â“À≈Õ¥≈¡∂Ÿ°¢â“ß ·μàÕ“®‰¡à™à«¬„Àâ„ à‰¥âμ”·Àπàß§«“¡ ≈÷°∑’ˇÀ¡“– ¡ ¥—ßπ—Èπ°“√„™â FOB ‡æ◊ËÕ¬◊π¬—πμ”·ÀπàߢÕß DLT ®÷߬—ß¡’§«“¡®”‡ªìπÕ¬Ÿà Õ¬à“߉√°Áμ“¡°“√„ à·°π≈«¥ μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§ÕÕ“®∑”„À⇰‘¥°“√∫“¥‡®Á∫¢Õ߇¬◊ËÕ∫ÿ À≈Õ¥§Õ·≈–À≈Õ¥≈¡ ‰ª®π∂÷ß¿“«–·∑√°´âÕπ∑’Ë√ÿπ·√ß§◊Õ °“√©’°¢“¥¢Õß∑àÕÀ≈Õ¥≈¡·≈–À≈Õ¥‡≈◊Õ¥ pulmonary ‚¥¬ ¡’√“¬ß“π«à“ °“√©’°¢“¥¢Õß∑àÕÀ≈Õ¥≈¡ —¡æ—π∏å°—∫§«“¡¥—π ¿“¬„π bronchial cuff17-21 „π°“√»÷°…“§√—Èßπ’ȉ¡à‰¥â„™â FOB àÕߥŸ°“√∫“¥‡®Á∫¢Õ߇¬◊ËÕ∫ÿÀ≈Õ¥§Õ·≈–À≈Õ¥≈¡À≈—߇ √Á® ºà“μ—¥ ·μஓ°°“√μ‘¥μ“¡ºŸâªÉ«¬‰¡àæ∫°“√∫“¥‡®Á∫®π‡°‘¥°“√ ©’°¢“¥¢Õß∑àÕÀ≈Õ¥≈¡ ·≈–®“°°“√»÷°…“¢Õß Leiberman D. ·≈–§≥–12 æ∫«à“°“√∫“¥‡®Á∫¢Õ߇¬◊ÕË ∫ÿÀ≈Õ¥≈¡·≈–À≈Õ¥§Õ ∑’Ëæ∫§◊Õ °“√¡’®ÿ¥‡≈◊Õ¥ÕÕ°À√◊Õ∫«¡·¥ß ∫√‘‡«≥ Bronchial 17-21 ‚¥¬„π cuff ‡∑à“π—Èπ ´÷Ëß Õ¥§≈âÕß°—∫∑’ˇ§¬√“¬ß“π‰«â °≈ÿ¡à ∑’„Ë à¥«â ¬«‘∏„’ à·°π≈«¥μ≈Õ¥°“√„ à∑Õà À≈Õ¥§Õ·≈–«‘∏ª’ °μ‘ 166 «‘ —≠≠’ “√ ‰¡à·μ°μà“ß°—πÕ¬à“ß¡’π¬— ”§—≠∑“ß ∂‘μ‘ ·≈–‰¡àæ∫°“√©’°¢“¥ ¢Õ߇¬◊ËÕ∫ÿÀ≈Õ¥§Õ·≈–°“√©’°¢“¥¢ÕßÀ≈Õ¥≈¡ √ÿª °“√„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ‡æ‘Ë¡§«“¡ ”‡√Á®„π°“√„ à DLT ¢â“ߴ⓬‡¢â“À≈Õ¥≈¡´â“¬¡“°°«à“°“√ „ à¥â«¬«‘∏’ª°μ‘ ·μà‰¡à¡’º≈μàÕμ”·Àπàß∑’ˇÀ¡“– ¡¢Õß∑àÕ„π À≈Õ¥≈¡·≈–‰¡àæ∫¿“«–·∑√°´âÕπ∑’Ë√ÿπ·√ß °‘μμ‘°√√¡ª√–°“» ß“π«‘®—¬π’ȉ¥â√—∫∑ÿπ π—∫ πÿπ®“°§≥–·æ∑¬»“ μ√å ¡À“«‘ ∑ ¬“≈— ¬ ‡™’ ¬ ß„À¡à ·≈–¢Õ¢Õ∫§ÿ ≥ ∫ÿ § ≈“°√¿“§«‘ ™ “ «‘ —≠≠’«‘∑¬“ §≥–·æ∑¬»“ μ√å ¡À“«‘∑¬“≈—¬‡™’¬ß„À¡à ∑’Ë„Àâ §«“¡√à«¡¡◊Õ§√—Èßπ’ȇªìπÕ¬à“ߥ’ ‡Õ° “√Õâ“ßÕ‘ß 1. Benumof JL, Partridge BL, Salvatierra C, Keating J. Margin of safety in positioning modern double-lumen endotracheal tube. Anesthesiology 1987 ; 67 : 729-38. 2. Shulman GB. Connelly NR. Double lumen tube placement with Bullard laryngoscope. Can J Anaesth 1999 ; 46 : 232-4. 3. Klien U, Karzai W, Bloos F et al. Role of fiberoptic bronchoscopy in conjunction with the use of double-lumen tubes for thoracic anesthesia : a prospective study. Anesthesiology 1998 ; 88 : 346-50. 4. Smith GB, Hirsch NP, Ehrenwerth J. Placement of doublelumen endobronchial tubes. Correlation between clinical impressions and bronchoscopic findings. Br J Anaesth 1986 ; 58 : 1317-20. 5. Ehrenwerth J. Pro : Proper positioning of a double-lumen endobronchial tube can only be accomplished with endoscopy. J Cardiothorac Anesth 1988 ; 2 : 101-4. 6. Alliaume B, Coddens J, Deloof T. Reliability of auscultation in positioning of double-lumen endobronchial tubes. Can J Anaesth 1992 ; 39 : 687-90. 7. Lewis JW, Serwin JP, Gabriel FS, Bastanfar M, Jacoben G. The utility of a double-lumen tube for one-lung ventilation in a variety of noncardiac thoracic surgical procedures. J Cardiothorac Vasc Anesth 1992 ; 6 : 705-10. 8. Slinger PD. Fiberoptic bronchoscopic positioning of double-lumen tubes. J Cardiothorac Anesth 1989 ; 3 : 486-96. 9. Benumof JL. The positioning of a double-lumen endobronchial tube should be routinely determined by fiberoptic bronchoscopy. J Cardiothorac Vasc Anesth 1993 ; 7 : 513-4. ªï∑’Ë 33 ©∫—∫∑’Ë 3 °√°Æ“§¡-°—𬓬π 2550 16. Inoue S, Nishimine N, Kitaguchi K, Furuva H, Taniguchi S. Double lumen tube location predicts tube malposition and hypoxemia during one lung ventilation. Br J Anaesth 2004 ; 92 : 195-201. 17. Wagner DL, Gammage GW, Wong ML. Tracheal rupture following the insertion of a disposable double-lumen endotracheal tube. Anesthesiology 1985 ; 63 : 698-700. 18. Burton NA, Fall SM, Lyons T, Graeber GM. Rupture of the left main-stem bronchus with a polyvinylchloride double-lumen tube. Chest 1983 ; 83 : 928-9. 19. Foster JM, Lau OJ, Alimo EB. Ruptured bronchus following endobronchial intubation. A case report. Br J Anaesth 1983 ; 55 ; 687-8. 20. Heiser M, Steinberg JJ, MacVaugh H 3rd, Klineberg PL. Bronchial Rupture, a complication of use of the Robertshaw double-lumen tube. Anesthesiology 1979 ; 51 : 88. 21. Guernelli N, Bragaglia RB, Briccoli A, Mastrorilli M, Vecchi R. Tracheobronchial ruptures due to cuffed Carlens tube. Ann Thorac Surg 1979 ; 28 : 66-7. 10. Brodsky JB. Con : proper positioning of a double-lumen endobronchial tube can only be accomplished with the use of endoscopy. J Cardiothorac Anesth 1988 ; 2 : 105-9. 11. »‘√‘≈—°…≥å ÿ¢ ¡ªÕß. °“√„À⬓√–ß—∫§«“¡√Ÿâ ÷° ”À√—∫°“√ºà“μ—¥ ∑√«ßÕ°. Õ—ß°“∫ ª√“°“√√—μπå, «√¿“ ÿ«√√≥®‘π¥“, ∫√√≥“∏‘°“√. μ”√“«‘ —≠≠’«‘∑¬“. æ‘¡æå§√—Èß∑’Ë 3. °√ÿ߇∑æœ : ”π—°æ‘¡æå°√ÿ߇∑æ ‡«™°“√ 2548 ; 234-64. 12. Leiberman D, Littleford J, Horan T, Unruh H. Placement of left double-lumen endobronchial tubes with or without a stylet. Can J Anaesth 1996 ; 43 : 238-42. 13. Mallampati SR. Airway management. In : Barash PG, Cullen BF, Stoelting RK, eds Clinical anesthesia. 3rd ed. Philadelphia : Lippincort-Raven 1996 : 573-92. 14. Benumof JL. Separation of the two lungs (Double-Lumen Tube and Bronchial Blocker Intubation). In : Benumof JL, ed. Anaesthesia for Thoracic Surgery. 2nd ed. Philadelphia : W.B. Saunders Company 1995 : 330-89. 15. Hannallah MS, Benumof JL, McCarthy PO, Liang M. Comparison of three techniques to inflate the bronchial cuff of left polyvinylchloride double-lumen tubes. Anesth Analg 1993 ; 77 : 990-4. Appendix 1 Selection of Left Rüsch-Endobronchial tube Height (cm) Female Male < 165 cm. 35 Fr. 37 Fr. 165-179 cm 37 Fr. 39 Fr. > 179 cm 39 Fr. 41 Fr. Vol. 33, No. 3, July-September 2007 Thai Journal of Anesthesiology 167 °“√»÷°…“‡ª√’¬∫‡∑’¬∫§«“¡ ”‡√Á®„π°“√„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ¢â“ߴ⓬¥â«¬«‘∏’°“√„ à·°π≈«¥μ≈Õ¥ °“√„ à∑àÕÀ≈Õ¥§Õ°—∫«‘∏’ª°μ‘ ∫∑§—¥¬àÕ ¿Ÿ¡‘À≈—ß ∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ‡ªìπÕÿª°√≥å ”§—≠„π°“√™à«¬À“¬„®·∫∫«‘∏’·¬°ªÕ¥ ·μà∂â“μ”·ÀπàߢÕß∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√ŸÕ¬Ÿà „πμ”·Àπàß∑’ˉ¡à‡À¡“– ¡ ®–¡’º≈°√–∑∫μàÕ¿“«–ÕÕ°´‘‡®π„π°√–· ‡≈◊Õ¥ «—μ∂ÿª√– ß§å ‡æ◊ËÕ‡ª√’¬∫‡∑’¬∫§«“¡ ”‡√Á®°“√„ à∑àÕ À≈Õ¥§Õ™π‘¥ Õß√Ÿ¢â“ߴ⓬„πÀ≈Õ¥≈¡¢â“ߴ⓬ √–À«à“ß°“√„ à·°π≈«¥μ≈Õ¥°“√„ à°—∫«‘∏’ª°μ‘ «‘∏’°“√ ºŸâªÉ«¬®”π«π 60 §π ¡“ ºà“μ—¥∑√«ßÕ°∑’ˉ¡à‡√àߥà«π ‚¥¬°“√™à«¬À“¬„®¥â«¬«‘∏’·¬°ªÕ¥ (one-lung ventilation) ·≈–„™â∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ¢â“ߴ⓬ ºŸâªÉ«¬∑—ÈßÀ¡¥∂Ÿ°·∫àßÕÕ°‡ªìπ 2 °≈ÿà¡ Ê ≈– 30 §π ‚¥¬ C-group ‡ªìπ°≈ÿà¡§«∫§ÿ¡ ‰¥â√—∫°“√„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ¢â“ߴ⓬ ¥â«¬«‘∏’ª°μ‘ §◊Õ°“√„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ ‚¥¬¥÷ß·°π≈«¥ÕÕ°‡¡◊ËÕ bronchial cuff ¢Õß∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ ºà“π‡ âπ‡ ’¬ß ·≈â«À≈—ß®“°π—ÈπÀ¡ÿπ∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ∑«π‡¢Á¡π“Ãî°“ 90o ·≈â«¥—π∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ‡¢â“‰ª®π√Ÿâ ÷°«à“¡’·√ßμâ“π ·≈â«®÷ß À¬ÿ¥ à«π S-group ‡ªìπ°≈ÿà¡»÷°…“‰¥â√—∫°“√„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ¢â“ߴ⓬‡À¡◊Õπ«‘∏’ª°μ‘ ·μà®–¥÷ß·°π≈«¥ÕÕ°°ÁμàÕ‡¡◊ËÕ„ à∑àÕ À≈Õ¥§Õ™π‘¥ Õß√Ÿ‡ √Á® À≈—ß®“°π—Èπ®–μ√«® Õ∫μ”·Àπàß∑’ˇÀ¡“– ¡¢Õß∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ¥â«¬°≈âÕß àÕßÀ≈Õ¥≈¡™π‘¥„¬·°â« π”· ß (fiberoptic bronchoscope) º≈°“√»÷°…“ §«“¡ ”‡√Á®„π°“√„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ„π°≈ÿà¡ s-group Ÿß°«à“„π°≈ÿà¡ c-group (97% vs 74 %, p = 0.02) ·≈–°“√„ àπ—Èπ∑àÕÀ≈Õ¥§ÕÕ¬Ÿà„πμ”·Àπàß∑’ˇÀ¡“– ¡„π°≈ÿà¡ s-group ·≈– c-group Õ¬Ÿà∑’Ë 20% ·≈– 13% μ“¡≈”¥—∫ (p = 0.73) ‰¡àæ∫¿“«–·∑√°´âÕπ∑’Ë√ÿπ·√ß∑—Èß Õß°≈ÿà¡∑’Ë»÷°…“ √ÿª §«“¡ ”‡√Á®¢Õß°“√„ à∑àÕÀ≈Õ¥ §Õ™π‘¥ Õß√Ÿ¢ÕߺŸâªÉ«¬∑’Ë “¡“√∂„ à∑àÕÀ≈Õ¥§Õ™π‘¥ Õß√Ÿ‡¢â“À≈Õ¥≈¡´â“¬ ”‡√Á®æ∫«à“ °≈ÿà¡∑’Ë„ à·°π≈«¥μ≈Õ¥°“√„ à∑àÕÀ≈Õ¥§Õ ™π‘¥ Õß√Ÿ ¡’§«“¡ ”‡√Á®¡“°°«à“°≈ÿà¡∑’Ë„ à¥â«¬«‘∏’ª°μ‘Õ¬à“ß¡’π—¬ ”§—≠∑“ß ∂‘μ‘ 168 «‘ —≠≠’ “√ ªï∑’Ë 33 ©∫—∫∑’Ë 3 °√°Æ“§¡-°—𬓬π 2550