Mathias Stiller

Curriculum Vitae
Mathias Stiller
Dr. rer. nat.
Department of Phylogeography
Senckenberg Museum of Zoology
Königsbrücker Landstrasse 159
D - 01109 Dresden
Email: [email protected]
Phone: +49 1578 0210580
Current position
2013 - present
DAAD funded postdoctoral researcher at the
Senckenberg Museum of Zoology, Königsbrücker Landstrasse 159,
D - 01109 Dresden, and
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6,
D - 04103 Leipzig
Project: “Coevolution of beavers (Castor spec.) and beaver beetles
(Platypsyllus castoris).”
Education / qualifications
2010 - 2013
Postdoctoral research fellow at the
Department of Biology, Pennsylvania State University, University Park,
PA 16802, USA and since April 2012 at the Department of Ecology
and Evolutionary Biology, University of California Santa Cruz, Santa
Cruz, CA 95064.
NSF project: “Understanding the role of environmental change on the
long-term population dynamics of one surviving and two extinct arctic
mammals.”
PI: Dr. Beth Shapiro
2005 - 2009
Ph.D. student at the
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Thesis: “Employing next generation high-throughput sequencing
technology to improve the genetic analysis of extinct Carnivores.”
Supervisors: Prof. Michael Hofreiter and Prof. Svante Pääbo
Grade: 1.2 (magna cum laude)
1999 – 2005
Diploma in Biology (German equivalent to MSc) with specialisation on
Ecology, Zoology, Genetics and Molecular Medicin (Virology).
University of Leipzig, Leipzig, Germany.
Grade: 1.6
Thesis: “Analysis of chemical modifications, as revealed by substitution
patterns in ancient DNA sequences of subfossil wolves.
Supervisors: Prof. Martin Schlegel and Prof. Svante Pääbo
Grade: 1.2
1998 – 1999
Civil service at the „Median Clinic” in Bad Lausick, Germany
1993 – 1998
High school and Abitur at the Friedrich-Schiller Gymnasium in Bad
Lausick, Germany
Grade: 1.7
1986 – 1993
Primary school in Prießnitz, Germany
Grants and scholarships
2013
DAAD Rückkehrstipendium and travel grant
2005 – 2009
Max Planck Society PhD student scholarship
2001
DAAD travel grant for fieldwork in the Mata Atlântica, Brasil
List of publications
Non-peer-reviewed publications:
4
Knapp M., Finstermeier K., Horn S., Stiller M. and Hofreiter M. (2010) „Neue PCRTechnologien für alte DNA.“ BIOspektrum 05/10, 531-535.
3
Münzel S.C., Hofreiter M., Stiller M., Conard N.J., Bocherens H. (2009) „Neue
Ergebnisse zur Paläobiologie der Höhlenbären auf der Schwäbischen Alb
(Chronologie, Isotopie und Paläogenetik).“ Stalactite. Proccedings of the 14th
International Cave Bear Conference.
2
Stiller M., Horn S., Wolf R. and Selter D. (2005) „Über Kleinsäuger aus dem Altkreis
Torgau – erste Ergebnisse aus Gewölluntersuchungen.“ Veröffentlichungen des
Naturkundemuseums Leipzig 2005, 107-112.
1
Horn S., Stiller M. and Wolf R. (2004) „Weitere Analysen zum “simplex” – Muster
des M3 bei Feldmäusen (Microtus arvalis PALLAS) in Nordwest-Sachsen.“
Mitteilungen für sächsische Säugetierfreunde 1/2004, 23-25.
Monographs / book chapter:
6
Stiller M. and Hofreiter M. (2013) „An ancient DNA perspective on the cave bears
from Peştera cu Oase, Romania.“ book chapter in “Life and Death at the Peştera cu
Oase : a setting for modern human emergence” eds. Erik Trinkaus, Silviu Constantin
and João Zilhão, Human Evolution Series of Oxford University Press (OUP):159-167.
5
Stiller M. (2012) „Case Study: Targeted high-throughput sequencing of
mitochondrial genomes from extinct cave bears via direct multiplex PCR sequencing
(DMPS).” book chapter in: Methods in Molecular Biology 2012(840):171-6.
4
Knapp M., Stiller M. and Meyer M. (2012) „Barcoding for multiplex high-throughput
sequencing of ancient DNA.” book chapter in: Methods in Molecular Biology
2012(840):155-70.
3
Stiller M. and Fulton T.L. (2012) „Multiplex PCR amplification of ancient DNA.” book
chapter in: Methods in Molecular Biology 2012(840):133-41.
2
Fulton T.L. and Stiller M. (2012) „PCR Amplification, Cloning, and Sequencing of
Ancient DNA.” book chapter in: Methods in Molecular Biology 2012(840):111-9.
1
Stiller M. (2011) “Chronological and Systematic Position of Cave Bear Fauna from
Ajdovska jama near Krško (Slovenia)” book chapter in monograph ed. Rabeder G. &
Pacher M. Verlag der Österreichischen Akademie der Wissenschaften (20):79-86.
Peer-reviewed publications:
23 Stiller M.*, Molak M.*, Prost S., Rabeder G., Baryshnikov G., Rosendahl W., Münzel
S., Bocherens H., Grandal-d'Anglade A., Hilpert B., Germonpré M., Stasyk O.,
Pinhasi R., Rohland N., Mohandesan E., Ho S.Y.W., Hofreiter M. and Knapp M.
(2013) „Mitochondrial DNA diversity and evolution of the Pleistocene cave bear
complex.” submitted to Quaternary International.
22 Orlando L.*, Ginolhac A.*, Zhang G.*, Froese D., Albrechtsen A., Stiller M., Schubert
M., Cappellini E., Petersen B., Moltke I., Johnson P.L., Fumagalli M., Vilstrup J.T.,
Raghavan M., Korneliussen T., Malaspinas A.S., Vogt J., Szklarczyk D., Kelstrup
C.D., Vinther J., Dolocan A., Stenderup J., Velazquez A.M., Cahill J., Rasmussen M.,
Wang X., Min J., Zazula G.D., Seguin-Orlando A., Mortensen C., Magnussen K.,
Thompson J.F., Weinstock J., Gregersen K., Røed K.H., Eisenmann V., Rubin C.J.,
Miller D.C., Antczak D.F., Bertelsen M.F., Brunak S., Al-Rasheid K.A., Ryder O.,
Andersson L., Mundy J., Krogh A., Gilbert M.T., Kjær K., Sicheritz-Ponten T., Jensen
L.J., Olsen J.V., Hofreiter M., Nielsen R., Shapiro B., Wang J., Willerslev E. (2013)
„Horse molecular evolution as revealed by a 700,000 year old genome.” Nature
499(7456):74-8.
21 Bocherens H., Bridault A., Drucker D.G., Hofreiter M., Münzel S.C., Stiller M., and
van der Plicht J. (2013) „The last of its kind? Radiocarbon, ancient DNA and stable
isotope evidence from a late cave bear (Ursus spelaeus ROSENMÜLLER, 1794)
from Rochedane (France).” accepted to Quaternary International.
20 Prost S., Klietmann J., Stiller M., Nagel D., Rabeder G. and Hofreiter M. (2013)
„Size matters – morphological and phylogenetical analysis of late glacial shrews
(Sorex araneus and S. tundrensis).” Global Change Biology doi: 10.1111/gcb.12153.
19 Cahill J.A., Green R.E., Fulton T.L., Stiller M., Jay F., Ovsyanikov N., Salamzade R.,
St. John J., Stirling I., Slatkin M. and Shapiro B. (2013) „Genomic evidence for island
population conversion resolves conflicting theories of polar bear evolution.” PLoS
Genetics 9(3): e1003345.
18 Vilstrup J.T., Seguin-Orlando A., Stiller M., Ginolhac A., Raghavan M., Nielsen
S.C.A., Weinstock J., Froese D., Vasiliev S.K., Ovodov N.D., Clary J., Helgen K.M.,
Fleischer R.C., Cooper A., Shapiro B. and Orlando L. (2013) „Mitochondrial
phylogenomics of modern and ancient equids.” PLoS ONE 8(2): e55950.
doi:10.1371/journal.pone.0055950.
17 Germonpré M., Sablin M.V., Després V., Hofreiter M., Lázničková-Galetováe M.,
Stevens R.E. and Stiller M. (2013) „Palaeolithic dogs and the early domestication of
the wolf: a reply to the comments of Crockford and Kuzmin (2013).” Journal of
Archeological Sciences 40:786-792.
16 Ginolhac A., Vilstrup J., Stenderup J., Rasmussen M., Stiller M., Shapiro B., Zazula
G., Froese D., Steinmann K.E., Thompson J.F., AL-Rasheid K.A.S., Gilbert T.,
Willerslev E. and Orlando L. (2012) „Improving the performance of true-Single
Molecule Sequencing for ancient DNA.” BMC Genomics 13(1):177.
15 Letts B., Fulton T.L., Stiller M., Andrews T., MacKay G., Popko R. and Beth Shapiro
(2012) „Ancient DNA Reveals Genetic Continuity in Mountain Woodland Caribou of
the Mackenzie and Selwyn Mountains, Northwest Territories, Canada.” Arctic 65:8094.
14 Döppes D., Rabeder G. and Stiller M. (2011) „The Middle Wurmian Warm Period in
the High Alps.” Quaternary International 245(2):193-200.
13 Münzel S.C., Stiller M., Hofreiter M., Mittnik A., Conard N.J. and Bocherens H.
(2011) „Pleistocene bears in the Swabian Jura (Germany): genetic replacement,
ecological displacement, extinctions and survival.” Quaternary International
245(2):225-237.
12 Bocherens H., Stiller M., Hobson K.A., Pacher M., Rabeder G., Burns J.A., Tütken
T. and Hofreiter M. (2011) „Niche partitioning between two sympatric genetically
distinct cave bears (Ursus spelaeus and Ursus ingressus) and brown bear (Ursus
arctos) from Austria: isotopic evidence from fossil bones.” Quaternary International
245(2):238-248.
11 Prost S., Knapp M., Stiller M., Flemmig J. and Hofreiter M. (2010) „A phantom
extinction? Ancient DNA suggests that the extinct Don hare was an ecomorph of the
extant mountain hare.” Journal of Evolutionary Biology 23(9):2022-9.
10 Prost S., Smirnov N., Fedorov V., Sommer R., Stiller M., Nagel D., Knapp M. and
Hofreiter M. (2010) “Influence of climate warming on arctic mammals? New insights
from ancient DNA studies of the Collared Lemming Dicrostonyx torquatus.” PLoS
ONE 5(5):e10447.
9
Stiller M., Baryshnikov G., Bocherens H., Grandal d'Anglade A., Hilpert B., Münzel
S.C., Pinhasi R., Rabeder G., Rosendahl W., Trinkaus E., Hofreiter M. and Knapp M.
(2010) “Withering away – 25,000 years of genetic decline preceded cave bear
extinction.” Molecular Biology and Evolution 27(5):975-8.
8
Stiller M., Knapp M., Stenzel U., Hofreiter M. and Meyer M. (2009) „Direct multiplex
sequencing (DMPS) – a novel method for targeted high-throughput sequencing of
ancient and highly degraded DNA.” Genome Research 19(10), 1843-8.
7
Germonpré M., Sablin M.V., Stevens R.E., Hedges R.E.M., Hofreiter M., Stiller M.
and Jaenicke-Despres V. (2009) “The Belgian, Ukrainian and Russian fossil large
canids in comparison with recent dogs (Canis familiaris) and wolves (Canis lupus)
and Pleistocene dogs: osteometry, stable isotopes and ancient DNA.” Journal of
Archaeological Science 36, 473–490. (among the ten most cited papers in JAS from
2007-2010)
6
Richards M.P., Pacher M., Stiller M., Quilès J., Hofreiter M., Constantin S., Zilhão J.
and Trinkaus E. (2008) “Isotopic evidence for omnivory among European cave
bears: Late Pleistocene Ursus spelaeus from the Peştera cu Oase, Romania.”
Proceedings of the National Academy of Sciences, USA 105(2), 600-604.
5
Krause J., Unger T., Noçon A., Malaspinas A-S., Orestis Kolokotronis S., Stiller M.,
Spriggs H., Dear P-H., Briggs A-W., Bray S., O’Brien S., Rabeder G., Matheus P.,
Cooper A., Slatkin M., Pääbo S. and Hofreiter M. (2008) “Mitochondrial genomes
reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene
boundary.” BMC Evolutionary Biology 2008, 8:220.
4
Valdiosera C.E., Garcia N., Anderung C., Dalén L., Crégut-Bonnoure E., Kahlke RD., Stiller M., Brandström M., Thomas M.G., Arsuaga J.L., Götherström A. and
Barnes I. (2007) “Staying out in the cold: glacial refugia and mitochondrial DNA
phylogeography in ancient European brown bears. Molecular Ecology 16(24), 5140–
5148.”
3
Bradley B. J., Stiller M., Doran-Sheehy D. M., Harris T., Chapman C. A. Vigilant L.
and Poinar H. (2007) “Plant DNA sequences from feces: potential means for
assessing diets of wild primates.” American Journal of Primatology 69(6), 699-705.
2
Römpler H., Dear P. H., Krause J., Meyer M., Rohland N., Schöneberg T., Spriggs
H., Stiller M. and Hofreiter M. (2006) “Multiplex amplification of ancient DNA.” Nature
Protocols 1(2), 720-728.
1
Stiller M., Green R. E., Ronan M., Simons J. F., Du L., He W., Egholm M., Rothberg
J. M., Keates S. G., Ovodov N. D., Antipina E. E., Baryshnikov G. F., Kuzmin Y. V.,
Vasilevski A. A., Wuenschell G. E., Termini J., Hofreiter M., Jaenicke-Després V. and
Pääbo S. (2006) “Patterns of nucleotide misincorporations during enzymatic
amplification and direct large-scale sequencing of ancient DNA.” Proceedings of the
National Academy of Sciences, USA 103(37), 13578-84.
Conference / seminar contributions
Oral presentations:
6
Hofreiter M., Stiller M., Baryshnikov G. and Rabeder G. (2012) “Mitochondrial DNA
diversity and evolution of the late Pleistocene cave bear complex.” 18th International
Cave Bear Symposium, Baile Herculane, Romania, September 20th-22nd, 2012.
5
Stiller M. (2010) “Employing next generation high-throughput sequencing
technologies to improve the genetic analysis of extinct animals.” Invited talk in the
seminar series of the Institute of Molecular Evolutionary Genetics, Department of
Biology, Pennsylvania State University, USA, October 13th, 2010.
4
Pacher M., Stuart A.J., Baryshnikov G., Stiller M., Kosintsev P. and Vorobiev A.
(2009) “Cave bears of the Ural Mountains – a survey based on direct radiocarbon
dates, aDNA and morphometrical analysis.” 15th International Cave Bear
Symposium, Spisska Nova Ves, Slovakia, September 17th-20th, 2009.
3
Stiller M. (2009) “Targeted high-throughput sequencing of ancient mitochondrial
genomes.” Joint workshop of the EBD-CSIC & MPI-EVA in Sevilla, Spain, January
7th-8th, 2009.
2
Stiller M. (2008) “Progress in Cave Bear Genetics.” 14th International Cave Bear
Symposium, Appenzell, Switzerland, September 18th-22nd, 2008.
1
Stiller M. (2006) “Ancient DNA and stable isotopes from the cave bears of Peştera
cu Oase, Romania.” 12th International Cave Bear Symposium, Aridea, Greece,
November 2nd-5th, 2006.
Poster presentations:
10 Cahill J.A., Green R.E., Fulton T.L., Stiller M., Jay F., Ovsyanikov N., Salamzade R.,
St. John J., Stirling I., Slatkin M. and Shapiro B. – presented by Cahill J.A. –
„Genomic evidence for island population conversion resolves conflicting theories of
polar bear evolution.” Cold Spring Harbor, Biology of Genomes meeting, New York,
USA, May 7th-11th, 2013.
9
Stiller M., Cahill A.J., Froese D., St. John J., Wooller M., Wayne R.K., Zazula G. and
Shapiro B. „Targeted high-throughput sequencing of ancient DNA on a population
level scale.” Annual meeting of the Society of Molecular Biology and Evolution
(SMBE), Dublin, Ireland, June 23rd-26th, 2012.
8
Orlando L., Ginolhac A., Raghavan M., Vilstrup J., Rasmussen M., Stiller M., Zazula
G., Froese D., Thompson J.F., Steinmann K., Kapranov P., AL-Rasheid K.A.S., Kui
W., Yuen K., Luo Y., Qian Z., Schubert M., Johnson P., Moltke I., Lindgreen S., Vogt
J.K., Petersen B., Hofreiter M., Gilbert T., Sicheritz-Ponten T., Krogh A., Zhang G.,
Shapiro B., Wang J. and Willerslev E. – presented by Orlando L. – „Ancient horse
genomes In the next-next generation sequencing era.” International Plant and
Animal Genome (PAG XX) Conference, San Diego, USA, January 14th-18th, 2012.
7
Döppes D., Rabeder G. and Stiller M. – presented by D. Döppes – „War es im
Mittelwürm in den Alpen wärmer als heute?” 12. Österreichischer Klimatag
“AustroClim”, Vienna, Austria, September 21st-22nd, 2011.
6
Döppes D., Rabeder G. and Stiller M. – presented by D. Döppes – „The Middle
Wurmian Warm Period in the High Alps.” OIS 3 Stage Conference, Brno, Czech
Republic, March 15th-17th, 2010.
5
Münzel S.C., Stiller M., Pacher M. and Athen K. – presented by S.C. Münzel –
„Genetic results versus morphological and biometrical analysis – the case of Ursus
spelaeus (sensu lato).” Conference of the International Council for Archaeozoology
(ICAZ), Paris, France, August 23rd-28th, 2010.
4
Stiller M., Döppes D., Sher A., Sotnikova M., Baryshnikov G., Abramov A.,
Kosintsev P.A., Willerslev E., Germonpré M., Ivanoff D., Nussbaumer M., Sommer
R.S., Constantin S. and Hofreiter M. “Wolverine (Gulo gulo) population dynamics
through space and time.” Society for Molecular Biology and Evolution meeting,
Barcelona, Spain, June 5th-8th, 2008.
3
Stiller M., Stenzel U., Hofreiter M. and Meyer M. – presented by M. Meyer – „Highthroughput targeted sequencing of ancient and forensic DNA.” CSHL meeting: The
Biology of Genomes, New York, USA, May 6th-10th, 2008.
2
Stiller M., Knapp M., Hofreiter M. and Meyer M. “Resolving the phylogenetic
relationships among cave bears by using whole mitochondrial genome sequences.”
13th International Cave Bear Symposium, Brno, Czech Republic, September 20th24th, 2007.
1
Stiller M., Hofreiter M., Zilhão J., Constantin S., Quilès J., Richards M. and Trinkaus
E. “Ancient DNA and stable isotopes from the cave bears of Peştera cu Oase,
Romania.” IV International Mammoth Conference, Yakutsk, Russia, June 18th-22nd,
2007.
Scientific service
Former member of the Climate and Diversity Committee in the Biology Department of
the Pennsylvania State University (2010-2012)
Reviewing of scientific manuscripts on behalf of: Proceedings of the Royal Society
London Series B, Proceedings of National Academy of Sciences USA, Molecular
Biology and Evolution, Journal of Archeological Sciences, PLoS ONE and
Naturwissenschaften.
Scientific evaluation of research grant proposals for the Polish Academy of Sciences and
the Deutsche Forschungsgemeinschaft.