docEurofins BioAn methods 2011-12-03
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Eurofins BioAn methods 2011-12-03
01/2012 Eurofins / Available methods - Bioanalysis New New New New New New New Compound 1,25-Dihydroxyvitamin D3 (Calcitriol) 10-Hydroxy-oxcarbamazepine 17-Hydroxyprogesterone 25-Hydroxy vitamin D2, 25-Hydroxy vitamin D3 3-Bromo-pyruvate 6-Hydroxyprogesterone 6-Keto-progesterone 6-Mercaptopurine 6-O-Desmethyl Donepezil Acetyl-L-Leucine & Acetyl-D-Leucine Acetyl-L-Leucine & Acetyl-D-Leucine Acetyl-L-Leucine & Acetyl-D-Leucine Acetylsalicylic acid Acyclovir Acyclovir Acyclovir Adapalene Adenosine Alanine Alfentanyl Alprazolam, α-Hydroxyalprazolam Alprazolam, α-Hydroxyalprazolam Amlodipine Amoxicillin Amoxicillin Amoxicillin Amoxicillin, Ampicillin Anastrozole Androsterone glucuronide Asymmetric dimethylarginine (ADMA) Atracurium Atazanavir Bacitracin Benzoylecgonine Betamethasone Bisnorcymserine Bisnorcymserine Bupivacaine Buprenorphine Butanediol mononitrate (BDMN) Cadaverine Caffein Caffein Caffein Caffein + 4 metabolites Caffein, Paracetamol Calcium ion Candoxatril Candoxatril Candoxatrilat Carbamazepine Carbamazepine epoxide Carboplatin Carboplatin (free) Carboplatin (Pt) Carbosulfan, Carbofuran, 3-Hydroxy-carbofuran Carprofen Carprofen Cefaclor Species Matrix Platform LLOQ Units Human Human Human Human Rat Human Human Dog Human Rat Human Dog Dog Human Human Human Human Porcine Human Dog Human Human Human Human Human Pig Pig Human Human Human Human Human Bovine Human Human Dog Rat Human Rat Minipig Bovine Human Human Pig Human Human Human Human Human Human Human Human Human Human Human Plasma Plasma Plasma Serum Serum Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Serum Urine LCMSMS LC-UV LC-MS/MS LCMSMS LC-MS/MS LC-MS/MS LC-MS/MS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC LCMSMS LC-FLUO LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LC-UV LC-UV LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC LCMSMS LCMSMS GCMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS GCMS LCMSMS LCMSMS LCMSMS LC-UV LCMSMS LC-UV LCMSMS HPLC HPLC HPLC LC-UV HPLC LCMSMS LCMSMS ICP-AES LC-FLUO LCMSMS LCMSMS HPLC 15 6 2,5 5 10 10 10 1 0,2 0,5 1 1 3 10 10 100 pg/mL µg/mL ng/mL ng/mL ug/mL ng/mL ng/mL ng/g ng/mL µg/mL µg/mL µg/mL ng/g ng/mL ng/mL ng/mL ng/mL 10 50 0,1 1 0,2 50 50 50 50 2 5 0,05 20 50 75 5 0,1 µg/mL pg/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL µmol/L ng/mL ng/mL ng/mL µg/mL ng/mL 1 0,2 0,5 10 200 10 150 0,1 25, 50 10 50 50 50 0,5 0,4 50 50 250 25 ng/mL ng/mL ng/mL ng/mL ng/mL µmol/l ng/mL µg/mL ng/mL µmol/L ng/mL ng/mL ng/mL µg/mL µg/mL ng/mL ng/mL ng/mL ng/mL Cat Dog Human 1/8 Serum Plasma Plasma Plasma Urine Plasma Serum Urine Plasma Plasma Plasma Plasma Plasma Plasma Plasma Milk Urine Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Saliva Plasma Urine Plasma Serum Plasma Urine Urine Plasma Plasma Plasma Plasma Plasma Meat, Milk and eggs Plasma Plasma Plasma 01/2012 Eurofins / Available methods - Bioanalysis New Compound Cefaclor Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Cefdinir (CI-983) Ceftaroline Ceftaroline fosamil Ceftiofur Ceftiofur Ceftiofur Ceftiofur Ceftiofur Ceftiofur, Desfuroylceftiofur-related residues Ceftiofur, Desfuroylceftiofur-related residues Cephapirin, Desacetylcephapirin Cephapirin, Desacetylcephapirin Cephapirin, Desacetylcephapirin Cephapirin, Desacetylcephapirin Chlorhexidine New Cholesterol (free) Chondroitine sulfate Cimetidine Ciprofloxacin Ciprofloxacin New Ciprofloxacin Ciprofloxacine Cisapride Citizine Clavulanic acid Clobazam Clonazapam Clonazepam, 7-Aminoclonazepam Clonazepam, 7-Aminoclonazepam Cloprostenol Cloprostenol Cloprostenol Cloricromene, Cloricromene acid Cloricromene, Cloricromene acid Cocain Codeine Corapan Cortisol Cortisol, β-Hydroxycortisol Cotinine Cronolone Cronolone Cronolone Cronolone Cronolone Cronolone Cronolone Cronolone Species Matrix Platform Human Dog Human Human Human Human Human Human Rabbit Rat Rat Mouse Mouse Bovine Chicken Chicken Chicken Horse Bovine Bovine Bovine Bovine Bovine Bovine Human Human Urine Plasma Dialysate Fluid Milk Plasma Saliva Serum Urine Plasma Milk Plasma Serum Serum Plasma Fat Liver Muscle Plasma Fat Liver Fat Kidney Milk Muscle Plasma Plasma HPLC HPLC HPLC HPLC HPLC HPLC HPLC HPLC HPLC HPLC HPLC LC-MS/MS LC-MS/MS HPLC HPLC HPLC HPLC HPLC HPLC HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS Human Serum Capill. Electroph. Human Rabbit Rabbit Human Pig Human Human Human Human Human Human Human Bovine Dog Pig Dog Rat & Mouse Human Human Mouse Human Human Human Goat Goat Goat Goat sheep sheep sheep sheep Plasma Eye tissues Plasma Plasma Plasma Plasma Plasma Serum Plasma Plasma Plasma Urine Plasma Plasma Plasma Plasma Plasma Urine Urine Plasma Plasma Urine Saliva Fat Kidney Liver Muscle Fat Kidney Liver Muscle HPLC LCMSMS LCMSMS LCMSMS LCMSMS HPLC LCMSMS HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS GCMS GCMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS 3 0,25 0,25 0,25 0,25 0,25 0,25 0,25 0,25 2/8 LLOQ Units 7,5 50 ng/mL ng/mL 7,5 12,5 2,5 7,5 1 20 5 (4S), 15 (6S) ng/g ng/g ng/mL ng/g ng/mL µg/mL 40 2 1 100 ng/g ng/mL ng/mL ng/mL 0,5 50 10 4 0.1, 0.2 0.1, 0.2 0,05 0,03 0,1 20 5 5 5 10 20 ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL µg/mL µg/mL ng/mL nmol/L ng/mL ng/mL ng/g ng/g ng/g ng/g ng/g ng/g ng/g ng/g µg/mL 01/2012 Eurofins / Available methods - Bioanalysis New Compound Cyclosporin A Cyclosporin, Everolimus, Tacrolimus Cyclosporin, Everolimus, Tacrolimus Cyclosporine A Cytosine β-D-arabinofuranside monophosphate (Ara-CMP) Cytrabine (Ara-C or cytosine β-Darabinofuranoside) DEET Delta-1-Progesterone Dextromethorphan Dextromethorphan (free) Dextromethorphan (total) Dextrorphan Dextrorphan (free) Dextrorphan (total) Diazepam Diclofenac Diclofenac Dideoxyinosine Diflunisal Diflunisal Digoxin Digoxin Digoxin Digoxin Dilitiazem & metabolites Diphencyprone Diphencyprone Diphencyprone Diphencyprone DNOC Docetaxel, Everolimus Domperidone N-oxyde Donepezil Donepezil Donepezil Donepezil Donepezil, 6-O-Desmethyldonepezil Doxorubicin Doxorubicin Doxycyline hydrochloride Enalapril, Enalaprilate Erlotinib (Tarceva) Erythromycine Esomeprazole Ethacrynic acid Ethacrynic acid Ethinylestradiol Ethosuximide Etidronate Everolimus Everolimus Faslodex (Fulvestrant) Faslodex (Fulvestrant) Felodipine Fenofibric acid Fentanyl Finafloxacin Species Matrix Platform LLOQ Units Human Human Human Human Whole blood DBS Whole blood BAL LCMSMS LCMSMS LCMSMS LCMSMS 1 5, 0.4, 0.2 5, 0.4, 0.3 1 ng/mL ng/ml ng/mL ng/mL Dog/Human Plasma LC-MS/MS 50 ng/mL Dog/Human Plasma LC-MS/MS 50 ng/mL Rat Human Human Human Human Human Human Human Human Human Human Human Human Human Human Human Human Human Human Human Human Rat Rat Human Human Rat Dog Human Mouse Rat Human Rat Rat or Mouse Human Human animal Human Human Human Human Human Human Dog/Human Human Human animal Human Human Human Human Human Plasma Plasma Plasma Urine Urine Plasma Urine Urine Plasma Plasma Urine Plasma Plasma Urine Plasma Urine Plasma Urine Plasma Plasma Urine Plasma Urine Whole blood Whole blood Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Urine Plasma Plasma Plasma Whole blood Whole blood Plasma Plasma Plasma Plasma Plasma Plasma HPLC LC-MS/MS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC HPLC HPLC HPLC LCMSMS LCMSMS LCMSMS LCMSMS LC-UV LCMSMS LCMSMS LCMSMS LCMSMS HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LC-FLUO LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC GCMS HPLC LC-MS/MS LCMSMS LCMSMS LCMSMS LCMSMS GCMS LCMSMS LCMSMS LCMSMS 0,5 25 3 3 25 3 3 10 100 100 100 100 100 0,1 0,5 0,1 1 5 0,95 0,95 0,927 0,93 10 1, 0.2 0,5 0,5 0,2 0,5 0,5 0.2, 0.2 4 ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL nmol/L nmol/L ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL nmol/L nmol/L ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL µg/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL pg/mL ng/mL 3/8 50 0,5 1 30 10 100 100 5 20 50 0,4 0,1 1 0,25 0,5 25 20 5 01/2012 Eurofins / Available methods - Bioanalysis New Compound Finafloxacin Finasteride New Flucinolone acetonide Flunixin Flunixin Fluocinolone Acetonide Fluocinolone Acetonide Fluocinolone Acetonide Flurbiprofen Furosemide Furosemide Gabapentin Gabapentine, Flurbiprofen Gamma-hydroxybutyric acid (GHB) Gamma-hydroxybutyric acid (GHB) Gamma-hydroxybutyric acid (GHB) Ganciclovir Ganciclovir Gefitinib (Iressa) Gefitinib (Iressa) Gefitinib (Iressa) Gefitinib (Iressa), o-desmethyl metabolite Gefitinib (Iressa), o-desmethyl metabolite Gefitinib (Iressa), o-desmethyl metabolite Hydroxy Citric Acid Hydroxy-mitoglitazone (chiral) Hydroxy-mitoglitazone (chiral) Hydroxy-mitoglitazone (chiral) Ibuprofen Ibuprofen Ibuprofen Ibuprofen Ibuprofen (chiral) Ibuprofen (hydrolyzed and non-hydrolyzed) Ibuprofen metabolites (chiral, hydrolyzed and nonhydrolyzed) Indapamide Indole propionic acid (IPA) Indole propionic acid (IPA) Indomethacin Indomethacin New Iohexol Ioxilan Ioxilan Itraconazole Ketamine Ketamine Ketamine Ketamine, Norketamine Ketoconazole Ketoprofen Ketoprofen Lacidipine Lacosamide Lamotrigine Laudanosine L-Dopa Leflunomide Leukotriene E4 (LTE4) Species Matrix Platform LLOQ Units Human Human Human Human Human Rabbit Rabbit Rabbit Urine Plasma Plasma Plasma Urine Aqueous humour Retina Vitreous humour 100 ng/mL 1 100 100 0,4 2 0,4 ng/mL ng/mL ng/mL ng/mL ng/g ng/mL Human Human Human Human Human Minipig Rat Human Human animal Human Human Human Human Human Rat Human NHP Rat Human Human Human Dog Human Human Plasma Urine Plasma Plasma Plasma Plasma Plasma Plasma Urine Plasma Jejunal fluid Plasma Plasma Skin Tumor tissue Plasma Plasma Plasma Plasma Plasma Serum Urine Plasma Plasma Serum LCMSMS HPLC LCMSMS HPLC HPLC LCMSMS LCMSMS LCMSMS HPLC HPLC HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC HPLC LCMSMS HPLC HPLC LC-MS/MS HPLC HPLC 100 100 1,5 50, 25 100 100 500 40 100 1 0,5 0,5 1 6, 12 6, 12 100 000 50 50 50 5 5 5 ng/mL ng/mL µg/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL µg/mL ng/mL ng/mL ng/g ng/g ng/g ng/mL ng/mL ng/mL ng/mL µg/mL µg/mL Human Urine GC Human Human Human Human Human Human Human Human Human Guinea Pig Guinea Pig Guinea Pig Guinea Pig Human Human Human Human Human Human Human Rat Human Human Whole blood Plasma Urine Plasma Urine Plasma Plasma Urine Plasma CSF Perilymph Plasma Perilymph Plasma Plasma Urine Plasma Plasma Plasma Plasma Plasma Plasma Urine LCMSMS LCMSMS LCMSMS HPLC HPLC LC-UV LC-UV LC-UV LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC LCMSMS LCMSMS LCMSMS HPLC LCMSMS LCMSMS LCMSMS 1 10 10 100 100 10 0,2 1 2 0,2 2 0,2 0.2, 0.4 2 100 100 0,1 5 25 20 ng/mL ng/mL ng/mL ng/mL ng/mL µg/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL 10 5 ng/mL pg/ml 4/8 01/2012 Eurofins / Available methods - Bioanalysis New Compound Leuprolide Leuprolide Leuprolide Levetiracetam Levonorgestrel Lidocaine Lorazepam Meclofenamic acid Meclofenamic acid Mefenamic acid Mefenamic acid Metformin Metformin Methotrexate Methotrexate Methotrexate Methotrexate + 7-OH metabolite Midazolam, OH-midazolam Mitoglitazone, Hydroxy-mitoglitazone Mitoglitazone, Hydroxy-mitoglitazone Mitoglitazone, Hydroxy-mitoglitazone Mitoglitazone, Hydroxy-mitoglitazone Mitotan Mitotan, DDD, DDA Modafinil R & S Morphine Mycophenolic acid (free MPA) Mycophenolic acid (MPA), MPAG Mycophenolic acid (MPA), MPAG Mycophenolic acid (MPA), MPAG Mycophenolic acid (MPA), MPAG Mycophenolic acid (MPA), MPAG, AcMPAG N-acetyl-DL-Leucine Nalbuphine Naproxen Naproxen Naproxen Naproxen Naproxen R and S Netilmicin Netilmicin Nicotine, Cotinine Nifedipine Nimoxine Nisin Norgestomet Norgestomet Norgestomet Norgestomet Olanzapine Omeprazole Oseltamivir, Oseltamivir acid Oxaliplatin (Pt) Oxyphenylbutazone Oxyphenylbutazone Paclitaxel New Patent blue V Perempanel Peroxide Number Species Matrix Platform LLOQ Units Dog Human Rat Human Human Human Human Human Human Human Human Human Human Monkey Mouse Rat Human Human Human Mouse NHP Rat Dog Dog Human Human Human Dog Human Human Human Mouse Human Human Human Rat Dog Minipig Human Rabbit Rabbit Human Human Human Bovine Bovine Bovine Bovine Bovine Human Human Human Human Human Human Swab Other Human Corn Oil Plasma Serum Plasma Plasma Plasma Plasma Plasma Plasma Urine Plasma Urine Plasma Urine Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Urine Plasma Urine Plasma Plasma Urine Serum Plasma Plasma Urine Plasma Plasma Plasma Plasma Eye tissues Plasma Plasma Plasma Plasma Milk Fat Kidney Liver Muscle Plasma Plasma Plasma Plasma Plasma Urine Other Buffer Whole blood LCMSMS LCMSMS LCMSMS LCMSMS GCMS GCMS LCMSMS HPLC HPLC HPLC HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS GCMS GCMS LCMSMS GCMS LCMSMS HPLC HPLC LCMSMS HPLC LCMSMS LCMSMS LCMSMS HPLC LCMSMS LC-MS/MS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS ICP-AES HPLC HPLC LCMSMS LCMSMS LCMSMS 0,025 0,025 0,025 3 10 0,1 0,1 100 100 100 100 2 5 1 5 1 1 0,1 0.5, 5 5, 50 5, 50 5, 50 50 50 0,1 5 2,5 1 100 0.1, 1 1 6 50 0,2 100 100 ng/g ng/g ng/g µg/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL µg/mL ng/mL ng/g ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL µg/mL ng/mL µg/mL ng/mL µg/mL µg/mL ng/g ng/mL ng/mL ng/mL ng/mL 5000 200 Various 5 0,1 0,5 5 ng/mL ng/mL ng/g ng/mL ng/mL ng/mL ng/mL 0,1 0,1 0,1 0,1 0,5 0,5 0.1, 1 250 100 100 50 0,1 1 ng/g ng/g ng/g ng/g ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL pg/ml µg/mL ng/mL 5/8 01/2012 Eurofins / Available methods - Bioanalysis New Compound Phenobarbital Phenserine Phenserine Phenserine Phenserine Phenserine Phenserine Phenserine Phenserine Phenserine Phenserine tartrate Phenserine tartrate Phenserine tartrate Phenylbutazone Phenylbutazone New Phenylephrine Phenytoin Pinaverium bromide Pioglitazone, Hydroxy-pioglitazone Pioglitazone, Hydroxy-pioglitazone Pioglitazone, Hydroxy-pioglitazone Pioglitazone, Hydroxy-pioglitazone Piracetam Posiphen Posiphen Posiphen Posiphen Posiphen Prednisolone Prednisolone, Prednisone Prednisone Pregabalin Primidone Probenecid Probenecid Probenecid Probenecid Procainamide, N-Acetylprocainamide Progesterone Propoxyphene Propranolol, 4-Hydroxypropranolol New Prostaglandin E2 (PGE2) Puerarin Pyrixycam Pyruvic acid Pyruvic acid Ranitidine Remifentanil Remifentanil + metabolite Rheine Rheine Rheine Rheine Rheine Rheine Rifampicin Risperidone, 9-Hydroxyrisperidone S-Adenosyl Methionine (SAM) Salbutamol Species Matrix Platform LLOQ Units Human Dog Dog Human Human Human Mouse NHP Rat Rat Dog Human Rat Human Human Dog Human Human Human Mouse NHP Rat Human Dog Human Mouse NHP Rat Human Human Human Human Human Dog Human Human Rat Human Human Human Human Human Dog Human Cat Dog Human Sheep Human Dog Human Human Human Rabbit Rat Human Human Dog Human Plasma Plasma Urine CSF Plasma Urine Plasma Plasma Plasma Urine Plasma Plasma Plasma Plasma Urine Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Plasma Urine Plasma Plasma Plasma Plasma Plasma Urine Plasma Plasma Plasma Plasma Plasma Whole blood Whole blood Plasma Plasma Synovial fluid Urine Plasma Plasma Plasma Plasma Plasma Plasma HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC LCMSMS HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC HPLC HPLC HPLC HPLC HPLC LC-MS/MS LC-UV LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC LCMSMS LCMSMS LC-FLUO LC-FLUO LCMSMS LC-FLUO LC-FLUO LCMSMS LCMSMS HPLC LCMSMS GCMS 1,5 µg/mL 100 100 250 0,5 1 2, 2 5, 50 5, 50 5, 50 3 ng/mL ng/mL pg/mL µg/mL ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL 1 0.5, 1 0,5 0,5 2,5 ng/mL ng/mL ng/mL µg/mL µg/mL 100 100 ng/mL ng/mL 0,5 2, 5 0,5 10 80 50 1000 1000 10 0,1 0,1 5 20 20 250 5 5000 0,1 2 20 1 ng/mL ng/mL ng/mL pg/mL ng/g ng/mL ng/g ng/g ng/mL ng/mL ng/mL ng/mL ng/mL ng/ml ng/mL ng/mL ng/mL µg/mL ng/mL ng/g nmol/L 6/8 01/2012 Eurofins / Available methods - Bioanalysis New New New New New New New New New Compound Salbutamol Salictlic acid Salicylic acid Salicylic acid Serotonin Sildenafil, N-desmethyl-sildenafil Silybinin A & B Silybinin hemisuccinate A & B Simvastatin, Simvastatin β-hydroxyacid Sirolimus (Rapamycin) Solifenacine (Vesicare) Solifenacine (Vesicare) Spinosyn A, Spinosyn D, Milbemycin A3, Milbemycin A4 Spinosyn A, Spinosyn D, Milbemycin A3, Milbemycin A4 Sucrose Sufentanil Sulindac Sulindac Tacrolimus Tamoxifen Tamoxifen Tamoxifen E isomer Tamoxifen Z isomer Tamoxifen, 4-OH-Tamoxifen Tazarotene, Tazarotenic acid Terbutaline Teriflunomide (A77 1726) Testosterone (free) Testosterone, Dihydrotestosterone, 3-αAndrostanediol Theophylline Thyroxine (T4), Triiodothyronine (T3) Thyroxine (T4), Triiodothyronine (T3) Tiagabine Tianeptine, MC5 metabolite Tobramycin Tobramycin Tolbutamide Tolterodine, DD01 (5-HMT) Tolterodine, DD01 metabolite Tolterodine, DD01 metabolite Topiramate Trichloroacetic acid Triciribine (TCN) Triciribine phosphate (TCNP) Triptolide Triptolide Triptolide, Tripdiolide Tryptophane Tulathromycine Tulathromycine Tylosine A Tylosine D Tyramine Uracil-1-β-D-arabinofuranoside (Ara-U) Uracil-1-β-D-arabinofuranoside monophosphate (Ara-UMP) Species Matrix Platform LLOQ Units Human Dog Human Human Human Human Human Human Human Human Human Human Urine Plasma Plasma Urine Plasma Plasma Plasma Plasma Plasma Whole blood Plasma Urine GCMS LCMSMS HPLC HPLC LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS 10 30 100 100 0,15 1, 0.5 5 25 50 0,5 0,5 0,5 nmol/L ng/g ng/mL ng/mL ng/mL ng/mL ng/mL ng/mL pg/mL ng/mL ng/mL ng/mL Mouse Brain LCMSMS Mouse Plasma LCMSMS Dog Dog Human Human Human Human Rat Human Human Mouse Human Human Human Human Plasma Plasma Plasma Urine Whole blood Plasma Plasma plasma plasma Plasma Plasma Plasma Plasma Plasma LCMSMS LCMSMS HPLC HPLC LCMSMS LCMSMS LCMSMS LC-MS/MS LC-MS/MS LCMSMS GCMS GCMS LCMSMS LCMSMS 100 50 100 100 0,2 5 2 10 10 0.5, 0.5 0.02, 0.50 1 10 1 ng/mL pg/mL ng/mL ng/mL ng/mL ng/mL ng/mL pg/mL pg/mL ng/mL ng/mL nmol/L ng/mL pg/ml Human Plasma LCMSMS 20 pg/ml Human Human Human Human Human Rabbit Rabbit Human Human Human Human Human Rat Human Human Human Rat Rat Human Bovine Swine Pig Pig Human Dog Serum Plasma Plasma Plasma Plasma Eye tissues Plasma Plasma Serum Plasma Serum Plasma Plasma Plasma Plasma Plasma Tissues Plasma Plasma Liver Kidney Faeces Faeces Plasma Plasma HPLC LCMSMS LCMSMS LCMSMS LC-UV LCMSMS LCMSMS LCMSMS LCMSMS GCMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS HPLC LC-MS/MS 1 1, 0.5 10, 0.5 10 10 40, 300 5 1,5 µg/mL ng/mL ng/mL ng/mL ng/mL ng/g ng/mL ng/mL 0,3 ng/mL 1,3 500 1 10 2 20 6,12 5 ng/mL ng/mL ng/g ng/g ng/g ng/g ng/g µg/mL 0,3 1,5 µg/g µg/g 50 ng/mL Dog Plasma LC-MS/MS 50 ng/mL 7/8 01/2012 Eurofins / Available methods - Bioanalysis New Compound Species Matrix Platform LLOQ Units Ursodeoxycholic acid (ursodiol) Valganciclovir Valganciclovir Valproic acid Verapamil, Norverapamil Vinflunine Human Human Human Human Human Human Plasma Plasma Urine Whole blood Plasma Whole blood LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS LCMSMS 50 10 100 10 10 0,25 ng/mL ng/mL ng/mL µg/mL ng/mL ng/mL Vistarem Human Urine LC-UV 34,8 µmol/L Warfarin (R, S) Zonisamide ZT-1, Huperzine A Human Human Dog Plasma Plasma Plasma LCMSMS LCMSMS LCMSMS 25 5 1, 0.2 ng/mL µg/mL ng/mL 8/8
