Publications clés

Membres de l’équipe
Signalisation cellulaire et oncogenèse
Jacques Ghysdael Directeur de recherche CNRS
EQUIPE GHYSDAEL
Chef d'équipe
Tél : +33 1 69 86 31 52
Publications clés
Année de publication : 2017
Rocchetti F, Tran Quang C, Maragno AL, Nguyen J, Lasgi C, Ghysdael J. (2017 Jan 1)
The calcineurin protein phosphatase is dispensable for BCR-ABL-induced B-ALL
maintenance, propagation and response to dasatinib.
Leukemia : DOI : 10.1038/leu.2016.269
Année de publication : 2016
Amélie Trinquand, Nuno R Dos Santos, Christine Tran Quang, Francesca Rocchetti, Benedetta
Zaniboni, Mohamed Belhocine, Cindy Da Costa de Jesus, Ludovic Lhermitte, Melania Tesio,
Michael Dussiot, François-Loïc Cosset, Els Verhoeyen, Françoise Pflumio, Norbert Ifrah, Hervé
Dombret, Salvatore Spicuglia, Lucienne Chatenoud, David-Alexandre Gross, Olivier Hermine,
Elizabeth Macintyre, Jacques Ghysdael, Vahid Asnafi (2016 Sep 6)
Triggering the TCR Developmental Checkpoint Activates a Therapeutically
Targetable Tumor Suppressive Pathway in T-cell Leukemia.
Cancer discovery : 972-85 : DOI : 10.1158/2159-8290.CD-15-0675
Année de publication : 2015
Diana Passaro, Marta Irigoyen, Claire Catherinet, Stéphanie Gachet, Cindy Da Costa De Jesus,
Charlène Lasgi, Christine Tran Quang, Jacques Ghysdael (2015 Jun 8)
CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute
Lymphoblastic Leukemia.
Cancer cell : 769-79 : DOI : 10.1016/j.ccell.2015.05.003
INSTITUT CURIE, 20 rue d’Ulm, 75248 Paris Cedex 05, France | 1
Membres de l’équipe
Signalisation cellulaire et oncogenèse
C Tran Quang, S Leboucher, D Passaro, L Fuhrmann, M Nourieh, A Vincent-Salomon, J Ghysdael
(2015 Feb 26)
The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases
and is essential to survival and metastasis of mammary cancer cells.
Cell death & disease : e1658 : DOI : 10.1038/cddis.2015.14
Année de publication : 2014
D Bellanger, V Jacquemin, M Chopin, G Pierron, O A Bernard, J Ghysdael, M-H Stern (2014 Feb 1)
Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia.
Leukemia : 417-9 : DOI : 10.1038/leu.2013.271
Année de publication : 2013
S Gachet, E Genescà, D Passaro, M Irigoyen, H Alcalde, C Clémenson, S Poglio, F Pflumio, A Janin,
C Lasgi, S Dodier, M Soyer, G Duménil, J Ghysdael (2013 Dec 1)
Leukemia-initiating cell activity requires calcineurin in T-cell acute
lymphoblastic leukemia.
Leukemia : 2289-300 : DOI : 10.1038/leu.2013.156
Michaela Waibel, Vanessa S Solomon, Deborah A Knight, Rachael A Ralli, Sang-Kyu Kim, KellieMarie Banks, Eva Vidacs, Clemence Virely, Keith C S Sia, Lauryn S Bracken, Racquel CollinsUnderwood, Christina Drenberg, Laura B Ramsey, Sara C Meyer, Megumi Takiguchi, Ross A
Dickins, Ross Levine, Jacques Ghysdael, Mark A Dawson, Richard B Lock, Charles G Mullighan,
Ricky W Johnstone (2013 Nov 27)
Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven
malignancies and overcome acquired resistance to JAK2 inhibitors.
Cell reports : 1047-59 : DOI : 10.1016/j.celrep.2013.10.038
Année de publication : 2010
C Virely, S Moulin, C Cobaleda, C Lasgi, A Alberdi, J Soulier, F Sigaux, S Chan, P Kastner, J
Ghysdael (2010 Jun 1)
Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates
with BCR-ABL in a transgenic model of acute lymphoblastic leukemia.
Leukemia : 1200-4 : DOI : 10.1038/leu.2010.63
INSTITUT CURIE, 20 rue d’Ulm, 75248 Paris Cedex 05, France | 2