CURRICULUM VITAE
Transcription
CURRICULUM VITAE
1 CURRICULUM VITAE LAST NAME : GIANELLO FIRST NAME : Pierre BIRTHDATE : 5 November 1956 (Malmedy): BELGIUM CITIZENSHIP : BELGIAN MARITAL STATUS: Married: Laurette RENARD: M.D., Radiotherapy. Children: Daphné (1984) and Elodie (1988) MEDICAL SCHOOL (1974 to1981) " Facultés Universitaires Notre-Dame de la Paix (Namur: 1974-1977) " Université catholique de Louvain (Woluwe: 1977-1981) " Medical Doctor (June 1981): "Magna Cum Laude" SURGICAL TRAINING 1981 - 1983: General Surgery - Catholic University of Louvain (Saint-Luc Hospital): Department of Surgery Professor P.J. Kestens (Brussels). 1983 - 1984: General Surgery - Hospital "La Croix-Rousse" - Department of Surgery - Professor M.Pouyet, Professor J.Baulieux (Lyon). 1984 - 1985: General Surgery - Catholic University of Louvain (Saint-Luc Hospital): Department of Surgery Professor P.J. Kestens (Brussels). 1985 - 1986: Renal Transplant Unit and Endocrine Surgery - Catholic University of Louvain (Saint-Luc Hospital): Professor G.P.J. Alexandre (Brussels). 1986 - 1987: Experimental Surgery - Catholic University of Louvain (Medical School/Brussels): Professor L. Lambotte and G.P.J. Alexandre. 2 1987 - 1988: Renal Transplant Unit and Endocrine Surgery/Digestive Surgery: Catholic University of Louvain (Saint-Luc Hospital, Brussels): Professor G. Alexandre and Professor P.J.Kestens (Brussels). June 1988: Full trained Surgeon: General Surgery. INAMI : 1 28630 89 140 CLINICAL AND ACADEMIC COURSE 1988 - 1989: Resident - Renal Transplant Unit and Endocrine Surgery: Professor G. Alexandre - Saint-Luc Hospital/Catholic University of Louvain (Brussels). 1989 - 1991: Clinical Member Staff (“Chef de Clinique adjoint”) - Renal Transplant and Pancreas Unit Professor G. Alexandre – Saint-Luc Hospital/Catholic University of Louvain (Brussels). 1991 - 1994: Research Fellow: Transplant Biology Research Center (Professor D.H. Sachs). Massachusetts General Hospital, Surgery, Harvard Medical School, Boston, USA. September 1994: Catholic University of Louvain (Medical School), Brussels: Associate Professor (“Chargé de Cours académique”). February 1996: "Thèse d'Agrégation de l'Enseignement Supérieur"(Ph.D.) at Catholic University of Louvain (Medical School), Brussels. September 1997: Director of the "Laboratory of Experimental Surgery" at Catholic University of Louvain (Medical School), Brussels. June 1999: Vice-President of the Ph.D. School (Clinical Research) - Catholic University of Louvain (Medical School), Brussels. September 1999: President of the Academic Department of Surgery at Catholic University of Louvain (Medical School), Brussels. September 1999-2003: Member of the board of the Belgian Society of Transplantation. June 2000-2006: Member of the board of “Corps Académique (CORA)” at Catholic University of Louvain. October 2000: Professor of Surgery at Catholic University of Louvain (Medical School), Brussels. October 2001-2009: President of the Ph.D. School (Clinical Research). Catholic University of Louvain (Medical School), Brussels 3 October 2001-2009: President of the Animal Ethical Committee. September 2002-2009: Expert member at « Fonds National de la Recherche Scientifique ». FRSM: Commission Clinique. September 2002: President of the Academic Department of Surgery at Catholic University of Louvain (Medical School), Brussels: re-elected. January 2003-2007: President of the “Conseil de gestion de la Recherche” at Catholic University of Louvain (Medical School), Brussels. April 2003-2005: Member of the Jury of “Fondation Erasme” May 2003- : Member of the Jury of “Fondation Saint-Luc” June 2003-2005: Expert of evaluation of “INSERM Laboratories” - France October 2005: Medical School: Full Professor - Catholic University of Louvain (Medical School), Brussels. April 2006: President of the Academic Department of Surgery: re-elected September 2006: President of “Corps Academique (CORA)” of Catholic University of Louvain. September 2007-2009: Dean “responsible for research in Health Sciences Sector” at Catholic University of Louvain (Medical School), Brussels. September 2007- : President of the “Scientific board of Fondation Saint-Luc”. September 2009-January 2011 : Vice-rector for the “Health Sciences Sector” October 2011- : Research coordinator in Health Sciences Sector at Catholic University of Louvain, Brussels. MEMBERSHIP OF SCIENTIFIC SOCIETIES • Member of the Royal Belgian Society of Surgery. • Foreign Assistant of the Claude-Bernard University - Lyon Academy (1984). • Foundator Member of the French Society of Endocrine Surgery. • Member of the Belgian Society of Transplantation • Member of the French Society of Transplantation. • Member of the International Society of Transplantation 4 • Member of the American Society of Transplant Surgeon • Member of the European Society of Transplantation • Member of the European Society of Surgical Research • Member of the American Society of Immunology • Member of the Cell Transplant Society • Member of the board of “International Xenotransplantation Association”. • Member of national « Académie Royale de Médecine de Belgique ». EDITORIAL BOARD AND REVIEWER FOR SCIENTIFIC JOURNALS -Transplantation -Pediatric Transplantation -Xenotransplantation (associated editor) -Regular review for Transplant International, Kidney International, Biomaterials, American Journal of Transplantation, Diabetes, European Surgical Research... PAST EXPERIENCE IN EXPERIMENTAL SURGERY • University of Louvain Medical School (1982). Neurosurgery Unit: Microsurgery - Professor Stroobandt. • University of " La Croix Rousse" Lyon (France) (1983). Experimental Surgery: Oesophageal Surgery: Oesogastrectomy and local Curietherapy. Orthotopic Liver transplantation in beagles: Professor Baulieux, Doctor J.L Peix. • University of Louvain Medical School (1986-1988): Experimental Surgery: 1) Kidney transplantation across a species barrier (xenograft). Study of the mechanisms involved in hyperacute vascular rejection. 2) Study of the effect of atrial natriuretic peptide on ischemically injured kidney. Relationship with hypervolemia and mechanisms. Professor L.Lambotte and Professor G.P.J.Alexandre. • University of Harvard Medical School, Massachusetts General Hospital,Boston,USA (1991 - 1994) - Professor D.H.Sachs: Tolerance to primarily vascularized allografts in miniature swine. 5 Induction of tolerance across a species barrier (pig to non-human primates). AWARDS • "Antonin Poncet" Award, Lyon 1984 Simplified protocol of liver transplantation in Beagles. Barth X., Gianello P. and Peix J.L. • First Poster Price International Society of Transplantation: Helsinki (3-8 august 1986) Cyclosporin A plus low dose steroïds versus conventional therapy in cadaver kidney transplantation : A randomized trial. Gianello P., Squifflet J.P., Pirson Y., Stoffel M. and Alexandre G.P.J. • First Poster Price International Digestive Surgery Congress: (Jerusalem: 1-5 september 1986) Intraoperative ultrasound in biliary and pancreatic tumors. Gigot J.G., Gianello P., Dardenne A., Otte J.B. and Kestens P.J. • Horlait-Dapsens Foundation (1986): to study an experimental model of xenotransplantation in the laboratory of Experimental Surgery. • Association "Professor Jean Morelle" Award: (1989) European Award for promotion in experimental surgery for: "Atrial Natriuretic Factor : a protective substance against acute renal ischemia ? A room for it in kidney transplantation" • "Claude Simon" Award: (1989) Award of the End Stage Kidney Disease League (LIR) for " Beneficial effects of Atrial Natriuretic Peptide on Cyclosporine nephrotoxic side-effects". • Saint Luc" Foundation: (1991): to achieve a research fellowship in Boston, Massachusetts General Hospital, Harvard Medical School. • Euroliver Foundation Prize (1999): Mechanism of tolerance to primarily vascularized allograft in miniature swine • Euroliver Foundation Prize (2001): a study for the better knowledge of the immunological mechanisms involved in xenotransplantation. • “Octave – Dupont Foundation ” Prize (2003), Academie Royale de Médecine : cardiomyoplastie à l’aide de cellules souches stromales médullaires allogéniques dans un modèle porcin de cardiomyopathie ischémique. A. Poncelet, P. Gianello • « Thoratec » from the « Société Française de Transplantation » (2004) : Allogenic stemcells transplantation. 6 • Saint-Luc « Foundation » (2008) : for a research project transplantation. • Saint-Luc « Foundation » (2008) : for a research project on the development of a platform “big animal” in cardiac surgery. Study on porcine model of the coronary arteries, the cellular transplantation and the cardiac valves. • Saint-Luc « Foundation » (2012) : For a research project on the development of the pig islets transplantation with the aim of a clinical application; macroencapsulation and transgenesis of pig islets. on encapsuled islets WORKS PUBLISHED 1. Squifflet J.P., Pirson Y., Gianello P., Van Cangh P., Alexandre G.P.J. 1981. Safe Preservation of Human Renal Cadaver Transplants by Euro-Collins Solution up to 50 Hours. Transplant Proc 13:693-696. 2. Gianello P., Lerut J., Otte J.B., Kestens P.J. 1983. Cancer de l'estomac restant après chirurgie pour maladie ulcéreuse bénigne [Cancer of the gastric stump after surgery for benign ulcers]. Acta Gastroenterol.Belg. 46:27-38. 3. Gianello P., Lerut J., Otte J.B, Kestens P.J. 1983. Cancer de l'estomac restant après chirurgie pour maladie ulcéreuse bénigne. Rev Franç Gastroentérol 192:20-27. 4. Lerut J., Gianello P., Otte J.B, Kestens P.J. 1983. Le traitement des Pseudokystes du pancréas. Lyon Chir 72:154-159. 5. Gianello, P., J. Lerut, J.B. Otte, Kestens P.J. 1984. Les traumatismes du pancréas. [Injuries of the pancreas]. Acta Chir.Belg. 84:170-179. 6. Gianello, P., Squifflet J.P., Pirson Y, Alexandre G.P. 1984. Ischemic necrosis of the allograft ureter. Transplant.Proc. 16:1301-1303. 7. Lerut J., Gianello P., Otte J.B., Kestens P.J. 1984. La valeur de la duodenopancreatectomie céphalique dans les tumeurs du carrefour biliopancréatique [The value of proximal duodenopancreatectomy for tumors of the biliary-pancreatic junction]. Acta Chir.Belg. 84:313-318. 8. Lerut J., Gianello P., Otte J.B., Kestens P.J. 1984. Pancreatic pseudocyst. Analysis of surgical therapy in 58 patients. Acta Chir.Belg. 84:265-271. 9. Lerut J., Gianello P., Otte J.B., Kestens P.J. 1984. Pancreaticoduodenal resection : Surgical Experience and Evaluation of risk factors in 103 patients. Ann Surg 199:432-437. 10. Louagie Y.A., Gianello P., Kestens P.J., Bonbled F., Haot J.G. 1984. Vinylchloride induced hepatic angiosarcoma. Br.J.Surg. 71:322-323. 7 11. Otte J.B., Gianello P., Wese F.X., Claus D., Verellen G., Moulin D. 1984. Diverticulum formation after circular myotomy for esophageal atresia. J.Pediatr.Surg. 19:68-71. 12. Squifflet J.P., Jamart J., Gianello P., Pirson Y., Alexandre G.P. 1984. Successful human kidney preservation by intracellular electrolyte flush followed by cold storage for more than 48 hours. J.Urol. 131:125 13. Squifflet J.P., Gianello P., Pirson Y., Jamart J., Van Vyve E., Alexandre G.P.J. 1984. Successful long-term preservation of human cadaver renal allografts with Euro-Collins' solution. Transplant Proc 16:303-306. 14. Baulieux J., Gianello P., Peix J.L., Goudin J.L., Caillot J.L., Pouyet M. 1984. Les fistules oesophagiennes après cure de Hernie Hiatale. Lyon Chir 80:180-183. 15. Baulieux J., Gianello P., Cazagou J.F., Maillet P. 1985. Les tumeurs langerhansiennes hypo-glycémiantes: à propos de 20 cas. Lyon Chir 81:187-190. 16. Gianello P., Baulieux J., Maillet P. 1985. Les fistules oesophagiennes et gastriques après chirurgie de la jonction oeso-gastrique [Esophageal and gastric fistulas following surgery of the esophagogastric junction]. Acta Chir.Belg. 85:169-178. 17. Grandjean J.P., Dumas P.J., Gianello P., Beurlet J. 1986. Formes sténosantes graves du syndrome de "l'ulcère solitaire du rectum" : A propos de 2 observations. Lyon Chir 82:245-249. 18. Gigot J.F., Puttemans T., Gianello P., Dardenne A.N., Detry R., Otte J.B., Kestens P.J. 1985. Echographie peroperatoire en chirurgie hépato-biliaire :résultats préliminaires. [Intra-operative echography in hepato- biliary surgery. Preliminary results]. Acta Gastroenterol.Belg. 48:434-446. 19. Lerut, J., Gianello P., Otte J.B., Kestens P.J. 1985. Pancreaticoduodenal resection :surgical experience and evaluation of risk factors in 103 patients. In Year Book of Cancer:97-99. 20. Lerut J., Gianello P., Reynaert M., Otte J.B., Kestens P.J. 1985. Les fistules pancréatiques post-opératoires : Etude clinique sur une série de 114 duodénopancréatectomies céphaliques consécutives. Acta Chir Belg 85:205-210. 21. Lerut J., Gianello P., Otte J.B., Kestens P.J. 1985. Follow-up à long terme (3-15 ans) après intervention pour pancréatite chronique. Acta Gastroenterol Belg 48:609-610. 22. Lerut J., Gianello P., Otte J.B., Kestens P.J. 1985. Les anévrismes des branches du tronc coeliaque. J chir 122:93-100. 23. Lerut J., Gianello P., Haot J., Otte J.B., Kestens P.J. 1985. Le cancer ampullaire : à propos de 26 tumeurs réséquées chirurgicalement. Ann Chir 39:1-17. 24. Gigot J.F., Gianello P., Dardenne A.N., Pringot J., Detry R., Otte J.B., Kestens P.J. 1986. Intraoperative ultrasonography in endocrine pancreatic surgery: preliminary results in 6 8 cases of insulinoma. J.Belge.Radiol. 69:57-62. 25. Gigot J.F., Gianello P., Verhelst R., Reynaert M., Otte J.B., Kestens P.J. 1986. Le shunt péritonéo-veineux dans le traitement de l'ascite réfractaire du patient cirrhotique. [Peritoneovenous shunt in the treatment of intractable ascites in cirrhotic patients. UCL experience]. Acta Gastroenterol.Belg. 49:33-49. 26. Lerut J., Kartheuser A., Gianello P., Otte J.B., Kestens P.J. 1986. Les kystes Hydatiques du Foie[Hydatid cysts of the liver]. Acta Chir.Belg. 86:208-215. 27. Squifflet J.P., Pirson Y., Gianello P., Leclercq B., Stoffel M., Jamart J., Alexandre G.P.J. 1986. One haplotype matched related donor kidney transplantation. Analysis of 5 successive protocols. Transplant Proc 18:1093-1096. 28. Gianello P., Squifflet J.P., Pirson Y., Stoffel M., Dereme T., Alexandre G.P. 1987. Cyclosporine-steroids versus conventional therapy in cadaver kidney transplantation: analysis of a randomized trial at two years. Transplant.Proc. 19:1867-1872. 29. Gianello P., Krykstein A., Gigot J.F., Kartheuser A., Van Vyve E., Otte J.B., Kestens P.J. 1987. Les fistules pancréatico-thoraciques dans la pancréatite chronique. Sem Hôp Paris 63:3663-3666. 30. Gianello P., Squifflet J.P., Ponlot R., Stoffel M., Alexandre G.P.J. 1987. Mise en place d'une prothèse aortique et transplantation rénale simultanée. J chir 124:157-160. 31. Gianello P., Squifflet J.P., Pirson Y., Reynaert M., Kestens P.J., Alexandre G.P.J. 1987. Incidence, morbidité et traitement des complications digestives après transplantation rénale. Sem Hôp Paris 63:2105-2112. 32. Squifflet J.P., Pirson Y., Gianello P., Reding R., Latinne D., Veykemans F., and Alexandre G.P.J. 1987. Résultats actuels de la transplantation rénale. Louvain Med 106:11-14. 33. Gianello P., Gigot J.F., Berthet F., Dardenne A.N., Lambotte L., Rahier J., Otte J.B., Kestens P.J.. 1988. Pre- and intraoperative localization of insulinomas: report of 22 observations. World J.Surg. 12:389-397. 34. Gianello P., Squifflet J.P., Pirson Y., Reynaert M., Kestens P.J., Alexandre G.P.J. 1988. Gastroduodenal complications after Transplantation. Clin Transplant 4:221-222. 35. Rombouts J.J., Kallel S., Squifflet J.P., Gianello P., Alexandre G.P., Pirson Y. 1988. Cyclosporin A and osteonecrosis of the femoral head. J.Bone Joint Surg.Am. 70A:1575-1576. 36. Squifflet J.P., Carlier M., Pirson Y., Gianello P., Alexandre G.P. 1988. Effect of furosemide on dialysis requirement following cadaveric kidney transplantation . J.Urol. 139:386 37. Stoffel M., Gianello P., Squifflet J.P., Pirson Y. , and Alexandre G.P.. 1988. Effect of 9-(2-hydroxy-1-[hydroxymethyl] ethoxymethyl) guanine (DHPG) on cytomegalovirus 9 pneumonitis after renal transplantation. Transplantation 46:594-595. 38. Stoffel M., Pirson Y., Squifflet J.P., Lamy M., Gianello P., and Alexandre G.P. 1988. Treatment of cytomegalovirus pneumonitis with ganciclovir in renal transplantation. Transpl.Int. 1:181-185. 39. Gianello P., Squifflet J.P., Mathieu L., Latinne D., Rahier J, Renard L., and Alexandre G.P.J. 1989. Les allogreffes humaines de parathyroÎde. Lyon Chir 85:59-63. 40. Gianello P., Stoffel M., Squifflet J.P., Pirson Y., Alexandre G.P.J. 1989. Ganciclovir for cytomegalovirus infection in renal transplants recipients. Lancet 1:216-217. 41. Otte J.B., Squifflet J.P., Carlier M.C., de Hemptinne B., Gianello P., Dereme T., Alexandre G.P. 1989. Organ procurement in children--surgical, anaesthetic and logistic aspects. Intensive.Care Med. 15 Suppl 1:S67-S70. 42. Squifflet J.P., Gianello P., Nesa S., Alexandre G.P. 1989. Infants and very young children as kidney donors. Lancet 2:745 43. Gianello P., Ramboux A., Poelaert D., Squifflet J.P., Carlier M., Donckier J., Ketelslegers J.M., Lambotte L., Alexandre G.P.J. 1987. Effets bénéfiques de l'hormone natriurétique cardiaque sur la fonction rénale immédiate après ischémie par clampage chez le rat. Arch Belg Physiol Pharmacol 95:38-39. 44. Donckier J., Gianello P., Berbinschi A., Squifflet J.P., Carlier M., Ketelslegers J.M. 1988. Renal metabolism of Atrial Natriuretic Factor in end stage renal failure. Acta Clin Belg 43:72 45. Gianello P., Janssen T., Chatzopoulos C., Kartheuser A., Lambotte L., Squifflet J.P., Alexandre G.P. 1988. Beneficial effect of piracetam on renal blood flow in ischemically injured kidneys in the rat. Transplant.Proc. 20:914-916. 46. Gianello P., Poelaert D., Ramboux A., Squifflet J.P., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L., Alexandre G. 1988. Beneficial effect of atrial natriuretic factor on ischemically injured kidneys in rats. Transplant.Proc. 20:921-922. 47. Gianello P., Poelaert D., Ramboux A., Squifflet J.P., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L., Alexandre G. 1988. Beneficial effect of atrial natriuretic factor on ischemically injured kidneys in the rat. A new approach to improve early renal function. Transplantation 45:860-863. 48. Gianello P., Squifflet J.P., Carlier M., Jamart J., Pirson Y., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L., Alexandre G.P.. 1988. Beneficial effects of maximal hydration on early renal function after ischemia is mediated by atrial natriuretic factor. Transplant.Proc. 20:923-927. 10 49. Carlier M., Gianello P., Squifflet J.P., Donckier J., Ketelslegers J.M., and Alexandre G.P.. 1989. Correlation between atrial natriuretic peptide levels and cardiac filling pressures in renal transplant recipients. Transplantation 48:700-702. 50. Carlier M., Gianello P., Squifflet J.P., Pirson Y., Alexandre G.P.J. 1989. Effect of perioperative recipient management on initial renal allograft function . Clin Transplant 3:60 51. Gianello P., Squifflet J.P., Carlier M., Jamart J., Pirson Y., Mahy B., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L., Alexandre G.P.J. 1989. Evidence that atrial natriuretic factor is the humoral factor by which volume loading or mannitol infusion produces an improved renal function after acute ischemia. An experimental study in dogs. Transplantation 48:9-14. 52. Gianello P., Ramboux A., Poelart D., Jamart J., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L., Squifflet J.P., Alexandre G.P.. 1989. Prevention of acute cyclosporine nephrotoxicity by atrial natriuretic factor after ischemia in the rat. Transplantation 47:512-515. 53. Gianello, P. 1990. Atrial natriuretic factor: a protective role after acute renal ischaemia? A room for it in kidney transplantation? Acta Chir.Belg. 90:143-150. 54. Gianello P., Besse T., Gustin T., Chatzopoulos C., Lavenne Pardonge E., Ketelslegers J.M., Lambotte L., Squifflet J.P., Alexandre G.P.. 1990. Atrial natriuretic factor, arachidonic acid metabolites and acute renal ischemia: experimental protocol in the rat. Eur.Surg.Res. 22:57-62. 55. Gianello, P. 1990. ANP in the prevention of acute renal failure after transplantation [letter; comment]. Transpl.Int. 3:52 56. Gianello P., Squifflet J.P., Carlier M., Lambotte L., Ketelslegers J.M., Alexandre G.P. 1990. Atrial natriuretic factor: a protective role after acute renal ischemia? Is there room for it in kidney transplantation? Transpl.Int. 3:41-46. 57. Squifflet J.P., Caramuta U., Gianello P., Wese F., Opsomer R.J., Alexandre G.P. 1990. [Results of renal transplantation in children with obstructive uropathy due to malformations]. Acta Urol.Belg. 58:63-71. 58. Squifflet J.P., de Hemptinne B., Gianello P., Balladur P., Otte J.B., Alexandre G.P. 1990. A new technique for en bloc liver and pancreas harvesting. Transplant.Proc. 22:2070-2071. 59. Squifflet J.P., Pirson Y., Poncelet A., Gianello P., Alexandre G.P.. 1990. Unrelated living donor kidney transplantation. Transpl.Int. 3:32-35. 60. Squifflet J.P., Pirson Y., Poncelet A., Gianello P., Alexandre G.P.J. 1990. Unrelated living donor kidney transplantation. In New Developments in Solid Organ Transplantation. F. Claas, H. Gooszen and F. Van der Woude, eds. Boerhave Committee for Postgraduate Medical Education, University of Leiden, p.31-34. 11 61. Squifflet J.P., Vandeleene B., Gianello P., Pirson Y., Alexandre G.P.J. 1991. Pancreas Transplantation at the University of Louvain : Results of 2 successive techniques. Zeit Transplantationsmed 3:86-89. 62. Squifflet J.P., Gianello P., Pacetti G., Alexandre G.P. 1991. Etat actuel de la Transplantation Pancréatique [Current status of pancreas transplantation]. Acta Chir.Belg. 91:96-99. 63. Squifflet J.P., Vandeleene B., Gianello P., Alexandre G.P.J. 1991. Pancreas transplantation at the University of Louvain : results of 2 successive techniques. Eurotransplant Newsletter 90:13-16. 64. Squifflet J.P., Herman D., Piessevaux H., Chatzopoulos C., Gianello P., Piret L., Rahier J., Beckers C., Alexandre G.P.J. 1992. Nodules thyroïdiens et cancers de la thyroïde. Bilan de deux années d'activité chirurgicale. Louvain Medical 111:59-66. 65. Alexandre G.P.J., Squifflet J.P., Latinne D., De Bruyere M., Reding R., Gianello P., Carlier M., Pirson Y. 1987. Present experiences in a serie of 26 ABO-Incompatible Living Donor Renal Allografts. Transplant Proc 19:4538-4542. 66. Alexandre G.P.J., Gianello P., Latinne D., Carlier M., Dewaele A., Van Obbergh L., Moriau M., Marbaix E., Lambotte J.L., Lambotte L., Squifflet J.P. 1989. Plasmapheresis and splenectomy in experimental renal xenotransplantation. In Xenograft 25. M.A. Hardy, ed. Elsevier Science Publications, Amsterdam. 259-262. 67. Latinne D., Squifflet J.P., De Bruyere M., Pirson Y., Gianello P., Sokal G., Alexandre G.P. 1989. Subclasses of ABO isoagglutinins in ABO-incompatible kidney transplantation. Transplant.Proc. 21:641-642. 68. Alexandre G.P.J., Gianello P., Latinne D., Cosyns P., Carlier M., Squifflet J.P. 1991. Pig to baboon model in renal xenotransplantation. Minerva Chirurgica 46(S1):101-106. 69. Alexandre G.P.J., Latinne D., Gianello P., Squifflet J.P. 1991. Preformed cytotoxic antibodies and ABO incompatible grafts. Clin Transplantation 5:583-594. 70. Alexandre G.P.J., Latinne D., Carlier M., Moriau M., Pirson Y., Gianello P.,Squifflet J.P. 1991. ABO-incompatibility and organ transplantation. Transplant Rev 5:230-241. 71. Besse T., Duck L., Latinne D., Gianello P., Squifflet J.P., Lievens M., Tomasi J.P., Lavenne Pardonge E.M., Lambotte L., Alexandre G.P.J., Bazin H. 1994. Effect of plasmapheresis and splenectomy on parameters involved in vascular rejection of discordant xenografts in the swine to baboon model. Transplant.Proc. 26:1042-1044. 72. Latinne D., Gianello P., Smith C.V., Nickeleit V., Kawai T., Beadle M., Haug C., Sykes M., Lebowitz E., Bazin H., Colvin R., Cosimi A.B., Sachs D.H. 1993. Xenotransplantation from pig to cynomolgus monkey: approach toward tolerance induction. Transplant.Proc. 25:336-338. 12 73. Gianello P., Fishbein J., Besse T., Gustin T., Chatzopoulos C., Ketelslegers J.M., Lambotte L., Squifflet J.P. 1994. Measurement of the vasoconstrictive substances endothelin, angiotensin II, and thromboxane B2 in cold storage solution can reveal previous renal ischemic insults. Transpl.Int. 7:11-16. 74. Gianello, P. 1994. Elimination des anticorps naturels dans les xénogreffes discordantes [Elimination of natural antibodies in discordant xenografts]. Pathol.Biol.Paris. 42:225-229. 75. Powelson J., Cosimi A.B., Austen,Jr. W., Bailen M., Colvin R., Gianello P., Sablinski T., Lorf T., Kawai T., Tanaka M., Sachs D. 1994. Porcine-to-primate orthotopic liver transplantation. Transplant.Proc. 26:1353-1354. 76. Tanaka M., Latinne D., Gianello P., Sablinski T., Lorf T., Bailin M., Nickeleit V., Colvin R., Lebowitz E., Sykes M., Cosimi A.B., Sachs D.H. 1994. Xenotransplantation from pig to cynomolgus monkey: the potential for overcoming xenograft rejection through induction of chimerism. Transplant.Proc. 26:1326-1327. 77. Fishbein J.M., Gianello P., Nickeleit V., Vitiello D., Blancho G., Latinne D., Nakajima K., Rosengard B., Colvin R., Sachs D.H. 1993. Interleukin-2 reverses the ability of cyclosporine to induce tolerance to class I disparate kidney allografts in miniature swine. Transplant.Proc. 25:322-323. 78. Gianello P., Fishbein J.M., Sachs D.H. 1993. Tolerance to primarily vascularized allografts in miniature swine. Immunol.Rev. 133:19-44. 79. Fishbein J.M., Rosengard B.R., Gianello P., Nickeleit V., Guzzetta P.C., Smith C.V., Nakajima K., Vitiello D., Hill G.M., Sachs D.H. 1994. Development of tolerance to class II-mismatched renal transplants after a short course of cyclosporine therapy in miniature swine. Transplantation 57:1303-1308. 80. Gianello P., Blancho G., Fishbein J.F., Lorf T., Nickeleit V., Sachs D.H.S. 1994. Mechanism of cyclosporin-induced tolerance to primarily vascularized allografts in miniature swine: Effects of administration of exogenous IL-2. J. Immunol. 153:4788-4797. 81. Rosengard B.R., Fishbein J.M., Gianello P., Ojikutu C.A., Guzzetta P.C., Smith C.V., Sundt T.M., Nakajima K., Hill G.S., Sachs D.H. 1994. Retransplantation in miniature swine. Lack of a requirement for graft adaptation for maintenance of specific renal allograft tolerance. Transplantation 57:794-799. 82. Blancho G., Gianello P., Germana S., Baetsher M., Sachs D.H.S., LeGuern C. 1995. Molecular identification of porcine interleukin-10: regulation of expression in a kidney allograft model. Proc. Natl. Acad. Sci.92: 2800-2804. 83. Gianello P., Fishbein J.F., Rosengard B.R., Lorf T., Vitiello D., Arn J.S., and Sachs D.H.S. 1995. Tolerance to class I disparate renal allografts in miniature swine : Maintenance of tolerance despite induction of specific antidonor CTL responses. Transplantation 59: 772-777. 13 84. Gianello P., Lorf T., Yamada K., Fishbein J.F., Nickeleit V., Vitiello D., Sachs D.H.S.. 1995. Induction of tolerance to renal allografts across single-haplotype MHC disparities in miniature swine. Transplantation 59: 884-890. 85. Giangrande I., Gianello P., Lorf T., Vitiello D., LeGuern C., Sachs D.H.S. 1995. Humoral response of miniature swine tolerant to class I mismatched renal allografts. Transplant Proc.27: 559-560. 86. Gianello,P., Carlier M., Jamart J., Hulhoven R., Bernheim J., Ketelslegers JM., Squifflet JP. 1995. Effect of 1-28α-h atrial Natriuretic peptide on acute renal failure in cadaveric renal transplantation. Clinical Transplantation 9: 481-489. 87. Gianello P., Latinne D., Alexandre GPJ. 1995. Pig to baboon xenograft. Xeno 3: 26-30. 88. Sablinski T., Latinne D., Gianello P., Bergen K.S., Colvin R., Foley A., Hang-Zhou Hong T., Lorf T., Meehan S., Monroy R., Powelson J., Sykes M., Tanaka., Cosimi B., Sachs DH. 1995. Xenotransplantation of pig kidneys to nonhuman primates: development of the model. Xenotransplantation 2: 264-270. 89.Gianello, P., Yamada, K;, Fishbein, J., Lorf, T., Colvin, J., Nickeleit, V., Arn, S., Sachs, D.H.S. 1996. Long-term acceptance of primarily vascularized renal allografts inminiature swine involves:systemic tolerance versus graft adaptation. Transplantation 61: 503-506. 90. Havaux X., Hori S., Soares M., Gianello P., Bazin H., Latinne D. 1996 Processing of IgM-anti-IgM immune complexes by the liver of rat treated by anti-IgM monoclonal antibodies. Transplant. Proc. 28: 574. 91. Gianello P. and Sachs DH. 1996. Effect of MHC matching on the development of tolerance to primarily vascularized renal allografts: a study in miniature swine. Human Immunology 50: 110. 92. Gianello P., Saliez A., Bufkens X., Pettinger R., Misseleyn D., Hori S., Malfroy B., Lambotte L. 1996. EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion induced damage. Transplantation 62: 1664-1666. 93. Kestens P.G.,Gigot JF., Foxius A., Collard.A., Gianello P. 1996. Traitement chirurgical de la pancréatite chronique avec atteinte céphalique prédominante par double dérivation wirsungienne et reperméabilisation canalaire céphalique. Annales de Chirurgie 50: 853-864. 94. Blancho G., Gianello P., Lorf T., Germana S., Mourad G., Sachs D.H.S, LeGuern C. 1997. Molecular and cellular events implicated in local tolerance to kidney allografts in miniature swine. Transplantation 63: 26-33. 95.Bartholomew A., Latinne D., Sachs D., Gianello P., De Bruyère P., Squifflet JP., Alexandre GPJ., Comerford C., Saidman S., Cosimi A. 1997. Utility of Xenografts: lack of correlation between PRA and Natural Antibodies to swine. Xenotransplantation 4: 34-39. 14 96. Gianello P. 1997. Existe-t-il une place pour la thérapie génique en transplantation d'organes? Annales de Chirurgie 51 : 593-604. 97. Yamada K., Gianello P., Ierino F., Shimuzu A., Meehan S., Colvin R., Sachs D.H. 1997. Influence of the thymus on transplantation tolerance in miniature swine. Transplant. Proc. 29: 1076. 98. Sablinski T., Gianello P., Bailin M., Bergen K.S., Emery D.W., Fishman J., Foley A., Hatch T., Hawley B., Kozlowski T., Meehan S., Monroy R., Powelson J., Colvin R., Cosimi B., Sachs DH. 1997. Porcine to monkey bone marrow and kidney xenotransplantation. Surgery 121: 381-391. 99. Hori S., Havaux X., Latinne D., Bazin H., Lambotte L., Gianello P. 1997. Effect of graft preservation and IgM depletion on guinea pig to rat cardiac xenograft survival. Transplantation 63: 1554-1561. 100. Delrivière L., Havaux X., Latinne D., Bazin H., Kamada N., Gianello P. 1997. Administration of exogenous IL-2 abrogates spontaneous tolerance induction to liver allograft in rat but does not affect long term established tolerance. Transplantation 63: 1698-1701. 101. Yamada K., Gianello P., Ierino F., Lorf T., Shimizu A., Meehan S., Colvin R.B., Sachs D.H. 1997.Role of the thymus in transplantation tolerance in miniature swine: I. Requirement of the thymus for rapid and stable induction of tolerance to class-I mismatched renal allografts. J. of Exp. Med. 186, 4: 497-506. 102. Emery DW, Sablinski T, Shimada H, Germana S, Gianello P, Foley A, Shulman S, Arn S, Fishman J, Lorf T, Nickeleit V, Colvin RB, Sachs DH, LeGuern C. 1997. Expression of an allogeneic MHC DRB transgene, through retroviral transduction of bone marrow, induces specific reduction of alloreactivity. Transplantation 64(10):1414-1423 103. Xu Y., Lorf T., Sablinski T., Gianello P., Bailain M., Monroy R., Kozlowski T., Cooper D.K.C., Sachs D.H. 1998. Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galα1-3Galβ1-4βG1c-x immunoaffinity column. Transplantation 65: 172-179. 104. Gigot JF, Jamar F., Ferrant A., van Beers B.E., Lengele B., Pauwels S., Pringot J., Kestens PJ., Gianello P., Detry R. 1998. Inadequate detection of accessory spleens and splenosis with laparoscopic splenectomy. Surgical Endoscopy 12: 101-106. 105. Delrivière L., Gibbs P., Kobayashi E., Goto S., Kamada N., Gianello P. 1998. Detailed Modified Technique for Safer Harvesting and Preparation of Liver Graft in the Rat. Microsurgery 17: 690-696. 106.Delrivière L., Gibbs P., Kobayshi E., Kamada N., Lambotte L., Gianello P. 1998. A new technique of complete thymectomy in adult rats without tracheal intubation. Microsurgery 18:68. 15 107. Delrivière L.,Gibbs P., Kobayashi E., Goto S., Kamada N., Gianello P. 1998. Technical Details for Safer Venous and Biliary Anastomoses for Liver Transplantation in the Rat. Microsurgery 18:12-18. 108. Delrivière L., Havaux X., Latinne D., Hori S., Bazin H., Lambotte L., Gianello P. 1998. Orthotopic liver xenotransplantation from guinea pig to rat: an unsuitable model for anatomical and physiological reasons. Transplantation 66:112-115. 109. Gigot JF., Lengele B., Gianello P., Etienne J., Claeys N. 1998. Present status of laparoscopic splenectomy for hematologic diseases: certitudes and unresolved issues. Semin Laparosc Surg 5(3):147-67. 110. Yamada K., Gianello P., Ierino F., Fishbein J., Lorf T., Shimizu A., Colvin R.B., Sachs D.H. 1999. Role of the thymus in transplantation tolerance in miniature swine: II. Effect of steroids and age on the induction of tolerance to class I mismatched renal allografts. Transplantation 67:458-467. 111. Yamada K., Ierino F., Gianello P., Shimizu A., Colvin R.B., Sachs D.H. 1999. Role of the thymus in transplantation tolerance in miniature swine: III. Surgical manipulation of the thymus interferes with stable induction of tolerance to class I mismatched renal allografts. Transplantation:67:1112-1119. 112. Sablinski T., Emery D.W., Monroy R., Hawley R.J., Xu Y., Gianello P., Lorf T., Kozlowski T., Bailin M., Cooper D.K.C., Cosimi A.B., Sachs DH. 1999. Long-term discordant xenogeneic (porcine to primate) bone marrow engraftment in a monkey treated with porcinespecific growth factors. Transplantation: 67: 972-977. 113. Oike F., Talpe S., Otsuka M., Dehoux JP., Lerut J., Otte JB., Gianello P. 2000. A 12day course of FK506 allows long term acceptance of semi-identical liver allograft in inbred miniature swine. Transplantation: 69: 2304-2314. 114. Dehoux JP., Talpe S., Dewolf N., Otsuka M., Oike F., Jamar F., de la Parra B., Latinne D., Bazin H., Gianello P.. 2000. Effects on human and nonhuman primate immune response of a new rat anti-CD2 monoclonal antibody. Transplantation: 69: 2622-2633. 115. Dehoux JP., de la Parra B., Latinne D., Bazin H., Squifflet JP., Gianello P. 2000. Human and non-human primate anti-galactosyl response after injection of rat monoclonal antibody bearing galactosyl epitopes. Xenotransplantation: 7: 109-117. 116. Dehoux JP., Hori S., Talpe S., Bazin H., Latinne D., Soares MP., Gianello P. 2000. Specific depletion of preformed IgM antibodies by administration of anti-μ monoclonal antibody suppresses hyperacute rejection of pig to baboon renal xenografts. Transplantation: 70: 935946. 16 117. Otsuka M., Baru M., Delriviere L., Talpe S., Nur I.,Gianello P. 2000. In vivo liverdirected gene transfer in rats and pigs with large anionic multilamellar liposomes: routes of administration and effects of surgical manipulations on transfection efficiency. Journal of Drug Targeting: 8: 267-279. 118. Gianello P. 2000. Tolerance to primarily vascularized allograft in inbred miniature swine. Bulletin et Mémoires de l’Académie Royale de Médecine de Belgique: 155: 351-352 119. Gianello P. 2001. Preventing Hyperacute Rejection. Graft: 4: 18-22. 120. Oike F., Uryuhara K., Otsuka M., Dehoux JP, Otte JB., Lerut J., Gianello P. 2001. Simplified technique of orthotopic liver transplantation in pigs. Transplantation: 71: 328-331. 121. Talpe S., Oike F., Dehoux JP., Sempoux C., Rahier J., Otte JB., Gianello P. 2001. Posttransplant lymphoproliferative disorder after liver transplantation in miniature swine. Transplantation: 71: 1684-1688. 122. Dehoux J.P., de la Parra B., Latinne D., Bazin H., Gianello P. 2001. Effect in vitro and in vivo of a rat anti -CD2 monoclonal antibody (LO -CD2b) on pig to baboon xenogeneic cellular (T and Natural Killer cells) immune response. Xenotransplantation: 8: 193-201. 123. Gigot J.F., Metairie S., Etienne J., Hormans Y., Beers B.E., Sempoux C., Deprez P., Materne R., Geubel A., Glineur D., Gianello P. 2001. The surgical management of congenital liver cysts. Surg Endosc: 15: 357-363. 124. Dehoux J.P., Legrand E., Saliez A., Gianello P. 2001. Xenotransplantation. Revue de l’association belge des technologues de laboratoire: 28: 224-235. 125. Lalain S., Gianello P., Gouin E., Saï P. 2001. In vitro recognition and impairment of pig islet cells by baboon immune cells: similarity to human cellular reactions. Transplantation: 72: 1541-1548. 126. Gigot J.F., Deprez P., Sempoux C., Descamps C., Metairie S., Glineur D., Gianello P. 2001. Surgical management of intraductal papillary mucinous tumors of the pancreas. Arch Surg: 136: 1256-1262. 127. Lerut J., Cicarelli O., Mauel E., Ghererardyn R., Talpe S., Laterre P.F., Roggen F., Van leeuw V., Otte J.B., Gianello P. 2001. Adult liver transplantation and steroidazathioprine withdrawal in Cyclosporine based immunosuppression - 48-months results of a prospective study. Transplant International, 2001 Dec;14(6):420-8. 128. Dehoux J.P., de La Parra B., Latinne D., Bazin H., Gianello P. 2002. Characterization of baboon anti-porcine IgG antibodies during acute vascular rejection of porcine kidney xenograft. Xenotransplantation, 9(5):338-49. 17 129. Gigot J.F., Mabrut J.Y., Matairie S., Jamar F., Ferrant A., Van Beers B.E., Gianello P. 2002. Failures following laparoscopic splenectomy and their management with special reference to accessory spleens and splenosis. Problems in General Surgery, Vol 19,3, 80-94. 130. Watremez Ch., Roeseler.J., De Kock M., Clerbaux. Th., Detry B., Veriter C., Reynaert M., Gianello P., Jolliet Ph., Liistro G. 2003. An improved porcine model of stable metacholine-induced bronchospasm. Intensive Care Med..Vol 29, 119-125. 131. Donckier V., Loi P., Closset J., Nagy N., Quertinmont E., Le Moine O., Devière J., Goldman M., Gelin M., Gianello P. 2003. Preconditioning of donors with interleukin-10 reduces hepatic ischemia-reperfusion injury after liver transplantation in pigs. Transplantation, 75: 902-904. 132. Watremez C., Liistro G., deKock M., Roeseler J., Clerbaux T., Detry B., Reynaert M., Gianello P., Jolliet Ph. 2003. Effects of helium-oxygen on respiratory mechanics,gas exchange and ventilation-perfusion relationships in a porcine model of stable methacholineinduced brochospasm. Intensive Care Med. 29(9):1560-6. 133. Dehoux J.P., Gianello P. 2003. Xénotransplantation. Ann. Méd. Vét., 147:147-157. 134. Ni J, Moulin P, Gianello P, Feron O, Balligand JL, Devuyst O. 2003. Mice that lack endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis. J Am Soc Nephrol. 14:3205-16. 135. Dehoux J.P., Nizet Y., De La Parra B., Lecuivre C., Vergauwen M., Bazin H., Latinne D., Gianello P. 2003. Cell-mediated cytotoxicity to Porcine aortic endothelial cells is not dependent on Galactosyl residues when baboon peripheral blood lymphocytes are previously primed with pig xenoantigens. Transplantation, 76(12):1675-80. 136. Poncelet A., Gianello P. 2003. Cardiomyoplastie à l’aide de cellules souches stromales médullaires allogéniques dans un modèle porcin de cardiomyopathie ischémique. Bull Mem Acad R Med Belg., 158(5-6):315-320. 137. Ambiru S., Uryuhara K., Talpe S., Dehoux J.P., Jacobbi L., Murphy C.J., Mc. Anulty J., Gianello P. 2004. Improved survival of orthotopic liver allograft in swine by addition of trophic factors to University of Wisconsin solution. Transplantation, 77(2):302-19. 138. Hermoye L., Annet L., Lemmerling Ph., Peeters F., Jamar F., Gianello P., Van Huffel S., Van Beers B.E. 2004. Calculation of the renal perfusion and glomerular filtration rate from the renal impulse response obtained with MRI. Magnetic Resonance in Medicine, 51:1017-25. 18 139. Vagefi P.A., Ierino F.L., Gianello P.R., Shimizu A., Kamano C., Sachs D.H., Yamada K. 2004. Role of the thymus in transplantation tolerance in miniature swine. IV. The thymus is required during the induction phase but not the maintenance phase of renal allograft tolerance. Transplantation, 77:979-985. 140. Uryuhara K., Ambiru S., Dehoux J.P., Oike F.,Talpe S., Gianello P.2004. Thymectomy impairs but does not uniformly abrogate long-term acceptance to semi-identical liver allograft in inbred miniature swine temporarily treated with FK506. Transpantation, 77:1172-1180. 141. Otsuka M., Ambiru S., Uryuhara K., Herman P., Talpe S., Dehoux J.P., Jamar F., Gianello P. 2005. Early biological and immune response to semi-identical liver or kidney allograft in miniature swine. Transplant International, 18:78-88. 142. Dufrane D., Goebbels R.M., Guiot Y., Gianello P. 2005. Is the expression of GalA1,3Gal on porcine pancreatic islets modified by isolation procedure ? Transplantation Proceedings, 37:455-457. 143. Dufrane D., Goebbels R.M., Guiot Y., Squifflet J.P., Henquin J.C., Gianello P. 2005. A simple method using a polymethylpenten chamber for isolation of human pancreatic islets. Pancreas, 30(3):e51-e59. 144. Dufrane D., Goebbels R.M., Fdilat I., Guiot Y., Gianello P. 2005. Impact of porcine islets size on cellular structure and engraftment after transplantation : adult vs young pigs. Pancreas, 30(2):138-147. 145. Vercruysse J., d’udekem d’Acoz Y., Saliez A., Legrand E., Noirhomme P., Gianello P., Jacquet L.-M. 2005. Preliminary study to the development of a right ventricular assist device for the patients with univentricular heart : an animal model. Transplantationsmedizin, 17:S131-S135. 146. Lerut J., Van Thuyne V., Mathijs J., Lemaire J., Talpe S., Roggen F., Ciccarelli O., Zuckermann M., Goffette P., Hope J., Gianello P., Bazin H., Cornet A., Rahier J., Latinne D. 2005. Anti-CD2 monoclonal antibody and Tacrolimus in in adult liver transplantation. Transplantation, 80(9):1186-1193. 147. Dufrane D., van Steenberghe M., Guiot Y., Goebbels R.M., Saliez A., Gianello P. 2006. Streptozotocin-induced diabetes in large animals (pig/primates): role of GLUT2 transporter and β-cell plasticity. Transplantation, 81(1):36-45. 148. Dufrane D. , van Steenberghe M., Goebbels R-M., Saliez A., Guiot Y., and Gianello P. 2006. The influence of implantation site on the biocompatibility and survival of Alginate encapsulated pig islets in rats. Biomaterials, 27:3201-3208. 149. Dufrane D., Goebbels R.M., Saliez A., Guiot Y., and Gianello P. 2006. Six month survival of microencapsulated pig islets and alginate biocompatibility in primates : proof of concept. Transplantation, 81:1345-1353. 19 150. Dufrane D., D’hoore W., Goebbels R.M., Saliez A., Guiot Y., Gianello P. 2006. Parameters favouring successful adult pig islet isolations for xenotransplantation in “pig-toprimate” model. Xenotransplantation, 13(3):204-214. 151. Johansson H., Goto M., Dufrane D., Siegbahn A., Elgue G., Gianello P., Korsgren O., Nilsson B. 2006. Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation. American Journal of Transplantation, 6:305-312. 152. Poncelet A., Vercruysse J., Saliez A., Gianello P. 2007. Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo. Transplantation, 83(6):783-790. 153. Dehoux J.P., Gianello P. 2007. The importance of large animal models in transplantation. Frontiers in Bioscience, 12:4864-4880. 154. Cozzi E., Gianello P., Soulilou J.P. 2007. A new start for xenotransplantation research in the European Union. Xenotransplantation, 14(3):196-197 155. Machiels B., Gillet L., Nascimento Brito S.D., Drion P., Delforge C., Nizet Y., Gianello P., Bona C., Costes B., Markine-Goriaynoff N., Vanderplasschen A. 2007. Natural antibody--complement dependent neutralization of bovine herpesvirus 4 by human serum. Microbes and infection, 9(14-15):1530-1537 156. Boudry C., Buldgen A., Portetelle D., Gianello P., Théwis A., Leterme P., Dehoux J.P. 2007. Effect of bovine colostrum supplementation on cytokine mRNA expression in weaned piglets. Livestock Science, 108(1-3):295-298. 157. Okumi M., Fishbein J., Griesemer A., Gianello P., Hirakata A., Nobori S., Moran S., Samelson-Jones E., Shimizu A., Sachs D., Yamada K. 2008. Role of persistence of antigen and indirect recognition in the maintenance of tolerance to renal allografts. Transplantation, 85(2):270-280. 158. Dufrane D., Mourad M., van Steenberghe M., Goebbels R.M., Gianello P. 2008. Regeneration of abdominal wall musculofascial defects by a human acellular collagen matrix. Biomaterials, 29:2237-2248. 159. Dufrane D., Gianello P. 2007. Correction d’un diabète de type I chez le primate par greffe d’îlots pancréatiques porcins encapsulés. Bulletin et Mémoires de l’Académie royale de Médecine de Belgique, 162:439-450. 160. Dufrane D., Gianello P. 2008. Pig islet xenotransplantation into a nonhuman primate model [Overview]. Transplantation, 86(6):753-760. 161. Goto M., Tjernberg J., Dufrane D., Elgue G., Brandhorst D., Brandhorst H., Wennberg L., Kurokawa Y., Satomi S., Lambris J. Gianello P., Korsgren O., Nilsson B. 2008. Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation. Xenotransplantation, 15:225-234. 20 162. Poncelet A., Nizet Y., Vercruysse J., Hiel A.L., Saliez A., Gianello P. 2008. Inhibition of humoral response to allogeneic porcine mesenchymal stem cell with 12 days of tacrolimus. Transplantation, 86:1586-1595. 163. Lerut J., Mathys J., Verbaandert C., Talpe S., Ciccarelli O., Lemaire J., Bonaccorsi-Riani E., Vanthuyne V., Hetsch N., Roggen F., Reyck C., Goffette P., Latinne D., Orlando G., Rahier J., Sempoux C., Wallemacq P., Laterre P.F., Gianello P. 2008. Tacrolimus monotherapy in liver transplantation. One-year of a prospective, randomized, double-blind, placebo-controlled study. Annals of surgery, 248(6):956-967. 164. Lerut J., Bonaccorsi-Riani E., Finet P., Gianello P. 2009. Minimization of steroids in liver transplantation [Review]. Transplant International, 22(1):2-19. 165. Poncelet A., Dufrane D., Gianello P. 2009. Cellular Xenotransplantation [Review]. Current Opinion in Organ Transplantation, 14 (2):168-174. 166. Dehoux J.P., Gianello P. 2009. Accommodation and antibodies. Transplant Immunology, 21:106-110. 167. Dufrane D., Maillart J.F.,Aouassar N.,Goebbels R.M.,Guiot Y.,Gianello P. 2009. Native pancreatic α-cell adaptation in Streptozotocin-induced diabetic primates: importance for pig islet xenotransplantation. Xenotransplantation, 16(3):152-163. 168. Fawzi-Grancher S.,Goebbels R.M., Bigare E.,Cornu O.,Gianello P.,Delloye C., Dufrane D. 2009. Human tissue allograft processing: impact on in vitro and in vivo biocompatibility. Journal of Materials Science : Materials in Medicine, 20:1709-1720. 169. Dufrane D., Gianello P. 2009. Pig islets for clinical islet xenotransplantation [Review]. Current Opinion in Nephrology and Hypertension, 18(6):495-500. 170. Vériter S., Mergen J.,Goebbels R.M., Aouassar N., Grégoire C., Jordan B., Levêque P., Gallez B., Gianello P., Dufrane D. 2010. In Vivo selection of biocompatible alginates for islet encapsulation and subcutaneous transplantation. Tissue Engineering Part A, 16(5):1503-1513. 171. Flamez D., Roland I., Berton A., Kutlu B., Dufrane D., Beckers MC., De Waele E., Rooman I., Bouwens L., Clark A., Lonneux M., Jamar JF., Goldman S., Maréchal D., Goodman N., Gianello P., Van Huffel C., Salmon I. and Eizirik DL. 2010. A genomicbased approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cells specific biomarker. Diabetologia, 53(7):13721383. 172. Dufrane D., R.M. Goebbels, Gianello P. 2010. Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates Up to 6 months Without Immunosuppression. Transplantation, 90 (10):1054-1062. 21 173. Poncelet A., Hiel A.-L., Vercruysse J., Hermans D., Zech F., Gianello P. 2010. Intracardiac allogeneic mesenchymal stem cell transplantation elicits neoangiogenesis in a fully immunocompetent ischemic swine model. European journal of cardio-thoracic surgery, 38:781-787. 174. Igarashi Y., D’hoore W., Goebbels R.M., Gianello P., Dufrane D. 2010. Beta-5 Score to evaluate pig islet graft function in a primate preclinical model. Xenotransplantation, 17(6):449-459. 175. Dufrane D., Gianello P. 2011. Islets Xenotransplantation. Louvain Médical, 130(3):S13-S21. 176. Nizet Y, Gillet L, Schroeder H, Lecuivre C, Louahed J, Renauld JC, Gianello P, Vanderplasschen A. 2011. Antibody production by injection of living cells expressing non self antigens as cell surface type II transmembrane fusion protein. Journal of Immunological Methods, 367:70-77. 177. Veriter S., Aouassar N., Adnet P.Y., Paridaens M.S., Stuckman C., Jordan B., Karroum O., Gallez B., Gianello P., Dufrane D. 2011.The impact of hyperglycemia and the presence of encapsulated islets on oxygenation within a bioartificial pancreas in the presence of mesenchymal stem cells in a diabetic wistar rat model. Biomaterials, 32(26):5945-5946. 178. Schubert T., Xhema D., Veriter S., Schubert M., Behets C., Delloye C., Gianello P., Dufrane D. 2011. The enhanced performance of bone allografts using osteogenicdifferentiated adipose-derived mensenchymal stem cells. Biomaterials, 32(34):8880-8891. 179. Navez J., Yeung R., Remue C., Descamps C., Navez B., Gigot JF., Starkel P., Philippe M., Jouret-Mourin A., Van de Weerdt ML., Zech F., Gianello P., Deprez PH. 2012. Acute-phase response in pigs undergoing laparoscopic, transgastric or transcolonic notes peritoneoscopy with us or eus exploration. Acta Gastro-enterologica Belgica, 75(1):2834. 180. Dufrane D., Gianello P. 2012. Pig islet for xenotransplantation in humans: Structural and physiological compatibility for human clinical application. Transplantation Reviews, 26:183-188. 181. Dufrane D., Gianello P. 2012. Macro- or microencapsulation of pig islets to cure type 1 diabetes [Editorial]. World Jounal of Gastroenterology, 18(47):6885-6893. 182. Schubert T., Poilvache H., Galli C., Gianello P., Dufrane D. 2012. Galactosyl-knockout engineered pig as a xenogenic donor source of adipose MSCs for bone regeneration. Biomaterials, 34(13):3279-3289. 183. Schubert T., Lafont S., Beaurin G., Grisay G., Behets C., Gianello P., Dufrane D. 2013. Critical size bone defect reconstruction by an autologous three-dimensional osteogeniclike tissue made of differentiated adipose mesenchymal stem cells: proof of concept in two preclinical pig models. Biomaterials, 34(13):4428-4438. 22 184. Vériter S., Aouassar N., Beaurin G., Goebbels R.M., Gianello P., Dufrane D. 2012. Improvement of Pig Islet Function by In Vivo Pancreatic Tissue Remodeling: A “HumanLike” Pig Islet Structure With Streptozotocin Treatment. Cell Transplantation, in press. 185. Vériter S., Gianello P., Igarashi Y., Beaurin G., Ghyselinck A., Aouassar N., Jordan B., Gallez B., Dufrane D. 2012. Improvement of subcutaneous bioartificial pancreas vascularization and function by co-encapsulation of pig islets and mesenchymal stem cells in primates. Cell Transplantation, in press. 186. Vériter S., Gianello P., Dufrane D. 2013. Bioengineered Sites for Islet Cell Transplantation. Current diabetes reports, in press. BOOK CHAPTER 1. Baulieux, J. and P. Gianello. 1985. Les hémorragies dans les sigmoïdites aiguës. In : Travaux scientifiques du 86 ème Congrès Français de Chirurgie. Actualités Chirurgicales 2. Chirugie abdominale et digestive; Editions Masson; Paris: 28-32. 2. Baulieux, J. and P. Gianello. 1985. Les diverticules de l'œsophage : aspects chirurgicaux. In Actualités digestives médico-chirurgicales. 6ème série. Editions Masson, Paris:8-16. 3. Gianello, P., Squifflet, J.P., Mathieu, L.,Latinne, D.,Rahier, J., and Alexandre, G.P.J. 1987. Les allogreffes humaines de parathyroÎde. In Pathologie Parathyroïdienne et Apport de la Cryoconservation. Collection Fondation Merieux, Lyon.107-109. 4. Gianello, P. 1992. La conservation d'organes: physiopathologie des lésions liées à l'ischémie, la reperfusion et la conservation d'organes. In Collection d'anesthésiologie et de réanimation : Le prélèvement d'organes. P. Lang and D. Houssin, eds. Masson. 95-115. 5. Soares, M., Havaux, X., Cormont, F., Nisolle, F., Besse, T., Gianello, P., Latinne, D. and Bazin, H. 1997. The use of anti-μ mAb in xenotransplantation: potential approach to overcome vascular rejection. In Xenotransplantation, Second Ed. Ed. Spring-Verlag; Editor: D.K.C. Cooper, E.Kemp, JL Platt, DJG.White. Chap.29, 399-410. 6. Gianello, P., Soares, M., Latinne, D. 1998. Xenotransplantation. In Handbook of Vertebrate Immunology, Ed. Academic Press, Edited by Pastoret P.P., Griebel P., Bazin H., Govaerts. Chapter XVIII. , 619-634. 7. Dufrane, D. and Gianello, P. 2009. Microencapsulated islet xenotransplantation in the pig to primate model. In The Bioartificial Pancreas and Other Biohybrid Therapies, Publisher : Transworld Research Network. Edited by Hallé J.P., de Vos P., Rosenberg L. 451-469. ISBN : 978-81-7895-415-8 8. Dufrane, D. and Gianello, P. 2013. Pig islet xenotransplantation. In Transplantologia praktyczna, T.4. [Transplantology T.4 Practical advances in transplantation], Publisher : Oxford University Press. Authors : Leszek P., Foroncewicz B., Mucha K.Chapter 2, 15-34. ISBN : 97883-01-17324-1 23 9. Gianello, P. 2012. Xenotransplantation: past, present and future. In Solid organ transplantation in the regenerative medicine era, Publisher : Elsevier. Edited by Dr Orlando. Submitted. MEMBER OF JURY 1994: Master in Biomedical Science. Université catholique de Louvain. The one-third partial hepatectomy: a model to study various factors influencing liver regeneration by Gong Jian-Ping. 1997: Master in Biomedical Science. Université catholique de Louvain. Non-small cell lung cancer: general concepts and influence of compromised lung function on operative morbidity and mortality by Kwasi T.Etey, M.D. 1997: European Master in Society, Science and Technology. Université catholique de Louvain et Université Louis Pasteur de Strasbourg. Xenotransplantation: organs for everyone by Valérie Ulsemer. 1997: Ph.D. Thesis. Université catholique de Louvain B Faculté de Médecine B Département de Chirurgie B Service de Chirurgie Digestive. Laparoscopic surgery in hepatic, biliary and hematologic diseases: advantages, limits and complications by Jean-François Gigot, MD. 1998. Université catholique de Louvain - Faculté de Médecine - Service d’anesthésiologie Postoperative analgesia after orthopaedic limb surgery: are peripheral nerve blocks efficient techniques? By François J. Singelyn, MD. 1999: Ph.D. Thesis. Université catholique de Louvain. Induction d’une tolérance aux antigènes Tindépendants de type 2 chez la souris adulte à l’aide d’anticorps monoclonaux anti-Ig by A.Alami Chentoufi. 1999: Habilitation à diriger la recherche. Université de Nantes- Faculté de Médecine. Intracellular expression in pig cells of anti-alpha1,3galactosyltransferase single-chain FV antibodies reduces Gal alpha1,3Gal expression and inhibits cytotoxicity mediated by anti-Gal xenoantibodies by B. Vanhove. 1999. Université catholique de Louvain- Faculté de Médecine-Cardiologie. Etude de la réactivité des vaisseaux mammaires et gastro-épiploïques pour pontage coronaire by O.Gurné M.D. 2000: Ph.D. Thesis. Université de Nantes -Faculté de Médecine. Etude des anticorps anti-gal et anti-HLA en xénotransplantation by Nathalie Barreau. 2000: Ph.D. Thesis. University of Leuven (Medical School): Laboratory for experimental transplantation. Mechanism of T-Cell independent and dependent Xenograft tolerance in an athymic rat model by Gu-Liang XIA, MD. 2000. Ph. D. Thesis. Université catholique de Louvain (Medical school): Mont-Godinne University Hospital. Gastrointestinal motility disorders in critical illness: characterisation, pathophysiological considerations and clinical implications by Alain-M. Dive, MD. 24 2000. Ph.D. Thesis. Université catholique de Louvain (Faculté de Médecine) Etude des mécanismes de l’effet immunosuppresseur d’un anti-corps monoclonal anti-CD2 (LOCD2a) by Yannick Nizet. 2000. Ph.D. Thesis. Université Libre de Bruxelles (Faculté de Médecine) : Laboratoire d’immunologie expérimentale. Rôle de l’IL-4, de l’IL-5 et des éosinophiles dans les rejets des greffes de peau chez la souris by Alain Le Moine 2001. Université catholique de Louvain - Faculté de Médecine. Interventional cardiac catheterization in children: indications and limits by Caroline Ovaert, M.D. 2001. Ph.D. Thesis. University of Groningen. Human T cell responses in Xenotransplantation : an in vitro study of a human anti-pig model by S.Popma. 2001. Habilité à diriger la Recherche. Université de Nantes. Les gros modèles en xénotransplantation by G.Blancho. 2001. Ph.D. Thesis. Université de Nantes. Etude de la réponse immune aux îlots de pancréas porcins chez l’homme et le primate by S.Lalain. 2001. Ph.D. Thesis. Université catholique de Louvain - Faculty of medicine - Experimental surgery and immunology units. Development of rat monoclonal antibodies to prevent hyperacute and acute rejection of vascularized xenograft in a pig-to-baboon model by Jean-Paul Dehoux. 2001. Ph.D. Thesis. Université catholique de Louvain - Faculty of medicine – Interventional cardiac catheterization in children: indications and limits by Caroline Ovaert, M.D.. 2001. Master in Biomedical Science. Université catholique de Louvain (Institut interfacultaire des Sciences). Physical and chemical processing for a human dura mater substitute: in vitro biocompatibility to clinical application by Denis Dufrane. 2001. Master in Biomedical Science. Université catholique de Louvain (Faculté de Médecine) Ecole des Sciences Biomédicales. Comparaison de l’effet Nébivolol versus Aténol sur l’expression des NO-Synthases dans les cellules myocardiques by Alexandra Mory. 2002. Université catholique de Louvain - Faculté de Médecine - Département de pédiatrie Laboratoire d’Hépatologie Pédiatrique Epstein-Barr virus infection and related posttransplant lympho-proliferative diseases in pediatric liver transplant recipients by Françoise Smets,M.D. 2002. Ph.D. Thesis. Université catholique de Louvain - Cliniques universitaires Saint-Luc Département de Médecine interne et services associés. Positron emission tomography using 18Ffluorodeoxyglucose in patients with suspected tumour reccurence: diagnostic value and impact on patient management by Max Lonneux,M.D. 2002. Ph.D.Thesis. Université de Nantes. Xénogreffe d’îlots de Langerhans dans le diabète non autoimmun: intérêt du transfert de gène de molécules immunosuppressives dans les modèles porc/rat et rat/souris by Nicolas Potiron. 25 2002. Ph.D. Thesis. Université catholique de Louvain – Faculty of medicine – Pediatric department – Laboratoire d’hépatologie pédiatrique – Epstein-Barr virus infection and related posttransplant lymphoproliferative diseases in pediatric liver transplant recipients by Françoise Smets, M.D. 2002. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universtaires Saint-Luc – Département de Médecine Interne et services associés – Positron emission tomography using 18 F-fluorodeoxyglucose in patients with suspected tumour reccurence: diagnostic value and impact on patient management by Max Lonneux, M.D. 2002. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universitaires Saint-Luc – Département de Chirurgie et services associés – Mycophenolic acid monitoring and its application in kidney transplantation by M. Mourad, M.D. 2003. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universitaires Saint-Luc – Département des Soins Intensifs et des Urgences – Noninvasive positive pressure ventilation in the management of patients with acute respiratory failure in the emergency department by F. Thys, M.D. 2003. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universitaires Saint-Luc – Chirurgie plastique – Centre des Malformations Vasculaires – New clinical and molecular genetic criteria for infantile hemangiomas and venous malformations by L. M. Boon, M.D. 2003. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universitaires Saint-Luc – Départements de Radiologie et d’Imagerie Médicale – Etude quantitative de la microcirculation hépatique par résonance magnétique et scanographie by R. Materne, M.D. 2003. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universitaires Saint-Luc – Service des Urgences – Cliniques Universitaires de Mont-Godinne – Département RéanimationUrgences – Non invasive positive pressure ventilation for exacerbation of chronic obstructive pulmonary patient by D. Vanpee, M.D. 2003. Ph.D. Thesis. Université catholique de Louvain – Cliniques Universitaires Saint-Luc Départements de Radiologie et d’Imagerie Médicale – Détermination de l’apport et des limites de l’échographie dans le diagnostic des affections intestinales aiguës de l’adulte by E. Danse, M.D. 2004. Ph.D. Thesis. University of Leuven – Faculty of Medicine – Laboratory for Experimental Transplantation – Studies of T or B lymphocyte activation or tolerance in xenotransplantation by Y. Yan, M.D. 2004. Ph.D. Thesis. University of Nantes – Faculty of Medicine – Models of xeno and allo – transplantation in the baboon by J. Ashton-Chess, M.D. 2004. Ph.D. Thesis. University of Leuven – Faculty of Medicine – Mechanisms of tolerance after donor blood transfusion in rats by Kobayashi, M.D. 26 2006. Ph. D. Thesis. Université catholique de Louvain – Laboratory of Experimental Surgery – Encapsulation of pig islets by alginate matrix to correct streptozotocin-induced diabetes in primates without immunosuppression by Denis Dufrane, M.D. 2011. Ph. D. Thesis. Université catholique de Louvain – Cardiovascular Department – Laboratory of Experimental Surgery and Transplantation – Intracardiac allogeneic mesenchymal stem cell (MSC) transplantation. Can we translate the “in vivo” immune properties of MSC into an “in vivo” inflammatory model without immunosuppression? By Alain Jean Poncelet, MD. 2012. Ph.D. Thesis. Université catholique de Louvain – Institut de Recherche expérimentale et Clinique – Laboratory of Experimental Surgery and Transplantation – Improvement of a subcutaneous bioartificial pancreas : study of different alginate compositions and improvement of islets survival and function. By Mrs Sophie Veriter. PARTICIPATION TO CONGRESS AND SCIENTIFIC SOCIETIES XVth EUROPEAN SURGICAL RESEARCH - BRUSSELS - Ist may 1980 INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY - BOSTON 29 june to 5 july 1980 1. Squifflet J.P., Pirson Y., Gianello P., Van Cangh P. and Alexandre G.P.J. Safe preservation of human renal cadaver transplants by Euro-Collins solution up to 50 hours. THEME EUROPEEN A NICOSIE - CHYPRE - 12 Septembre 1982 Président : Prof. P. Mallet-Guy. 2. Lerut J., Gianello P., Otte J.B. et Kestens P.J. Le traitement des pseudokystes du pancréas. SOCIETE ROYALE BELGE DE GASTRO-ENTEROLOGIE - BRUXELLES - 26 Février 1983 3. Gianello P., Lerut J., Otte J.B. et Kestens P.J. Le cancer du moignon gastrique après chirurgie pour maladie ulcéreuse bénigne. 4. Lerut J., Gianello P., Otte J.B. et Kestens P.J. Les pseudokystes du pancréas : à propos de 64 cas. INTERNATIONAL CONGRESS OF ORGAN PROCUREMENT-MAASTRICHT- 14 to 16 april 1983 5. Squifflet J.P., Gianello P., Pirson Y., Jamart J., Van Vyve E. and Alexandre G.P.J. Successful long-term preservation of human cadaver renal allografts with Euro-Collins solution. CONGRES BELGE DE CHIRURGIE - BRUXELLES - 20 avril 1983 6. Gianello P., Lerut J., Otte J.B. et Kestens P.J. Les traumatismes du pancréas. 27 SOCIETE BELGE DE GASTRO-ENTEROLOGIE - BRUXELLES - 7 Mai 1983 7. Lerut J., Gianello P., Otte J.B. et Kestens P.J. Les tumeurs du carrefour bilio-pancréatique : la valeur de la duodeno-pancréatectomie céphalique. 30th ANNUAL CONGRESS INTERNATIONAL OF "BRITISH ASSOCIATION OF PEDIATRIC SURGEONS" - LONDRES - 20 to 22 july 1983 8. Otte J.B., Gianello P., Moulin D., Verellen G., Claus D. and Wese F.X. Pseudodiverticular dilatation after myotomy for esophageal atresia repair. INTERNATIONAL COLLEGE OF SURGEONS - ANVERS - September 1983 - "The Prothesis in Surgery" 9. Lerut J., Reynaert M., Gianello P., Otte J.B. and Kestens P.J. Peritoneo-venous drainage in refractory ascites (Le Veen and Denver Shunt). FIRST CONGRESS OF E.S.O.T. - ZURICH - 23 to 25 November 1983 10. Gianello P., Squifflet J.P., Pirson Y. and Alexandre G.P.J. Ischemic necrosis of the allograft ureter. REUNION ANNUELLE DES SOCIETE ROYALE BELGE DE GASTRO-ENTEROLOGIE, DE CHIRURGIE ET DE RADIOLOGIE - LEUVEN - 10 Décembre 1983 11. Lerut J., Gianello P., Otte J.B. et Kestens P.J. Les anévrismes du tronc coeliaque. SOCIETE DE CHIRURGIE DE LYON - LYON - 15 Décembre 1983 12. Baulieux J., Gianello P., Peix J.L., Gaudin J.L., Caillot J.L. et Pouyet M. Les fistules oesophagiennes après cure de hernie hiatale. COLLOQUE MENSUEL HOPITAL DE LA CROIX-ROUSSE (CHU) - LYON - 20 Janvier 1984 13. Gianello P. et Baulieux J. Les diverticules pharyngo-oesophagiens (Zenker) JOURNEES ANNUELLES MEDICO-CHIRURGICALES - NICE - 3 au 5 Février 1984 14. Gianello P. et Baulieux J. Les diverticules de l'oesophage : aspects chirurgicaux. JOURNEES ANNUELLES LYONNAISES DE CHIRURGIE - LYON - 23 au 24 Février 1984 15. Baulieux J., Peix J.L. et Gianello P. Drainage des anastomoses colo-rectales basses par drains de shirley. 28 COLLOQUE MENSUEL HOPITAL DE LA CROIX-ROUSSE - LYON - 27 mars 1984 16. Gianello P. et Kestens P.J. Les traumatismes fermés du pancréas. CONGRES BELGE DE CHIRURGIE - BRUXELLES - 4 mai 1984 17. Gianello P., Baulieux J. et Maillet P. Les fistules oesophagiennes et gastriques après chirurgie de la jonction oeso-gastrique. 18. Lerut J., Gianello P., Otte J.B. et Kestens P.J. Les fistules pancréatiques postopératoires : étude clinique d'une série de 114 DPC consécutives. 8th WORLD CONGRESS OF THE COLLEGIUM INTERNATIONALE CHIRURGIE DIGESTIVAE - AMSTERDAM - 11 to 14 September 1984 19. Lerut J.P., Gianello P., Reynaert M., Otte J.B. and Kestens P.J. Pancreatic fistula after pancreaticoduodenal resection. 20. Lerut J.P., Gianello P., Reynaert M., Otte J.B. and Kestens P.J. Correlation between histopathology and survival in and ampullary tumors. 21. Lerut J.P., Gianello P., Reynaert M., Otte J.B. and Kestens P.J. Ampullary cancer : experience in 26 surgically resected tumors. 22. Lerut J.P., Gianello P., Otte J.B. and Kestens P.J. Pancreatico-duodenal resection, surgical experience in 103 patients : evaluation of risk factors. 86ème CONGRES FRANCAIS DE CHIRURGIE, AFC - PARIS - 24 au 27 septembre 1984 23. Baulieux J. et Gianello P. Les hémorragies dans les sigmoïdites aiguës. CYCLE DE PERFECTIONNEMENT EN GASTRO-ENTEROLOGIE -U.C.L- 19 au 22 novembre 1984 24. Collard J.M., Gianello P., Otte J.B. et Kestens P.J. Résultats de la chirurgie anti-reflux. REUNION ANNUELLE DES SOCIETE BELGE DE GASTRO, DE CHIRURGIE ET DE RADIOLOGIE -BRUXELLES - 8 décembre 1984 25. Lerut J.P., Gianello P., Otte J.B. and Kestens P.J. Le traitement chirurgical de la pancréatite chronique : à propos de 100 cas. 9èmes JOURNEES FRANCOPHONES D'HEPATOLOGIE ET DE GASTROENTEROLOGIE - BRUXELLES - 11 au 14 mars 1985 26. Grandgean J.P., Dumas P.J., Gianello P. et Beurlet J. Formes sténosantes graves du syndrome de l'ulcère solitaire du rectum. A propos de 2 observations. 29 SOCIETE ROYALE BELGE DE GASTRO-ENTEROLOGIE - BRUXELLES - 11 mai 1985 27. Gigot J.F., Dardenne A., Gianello P., Otte J.B. et Kestens P.J. L'échographie peropératoire en chirurgie hépato-biliaire. Xème COURS INTERNATIONAL D'IMMUNOLOGIE ET TRANSPLANTATION LYON - Juin 1985 28. Squifflet J.P., Gianello P., Pirson Y., Jamart J., Westelinck K. and Alexandre G.P.J. Ciclosporin versus Azathioprine and ALG for secondary renal allografts : A randomized Trial. 87ème CONGRES FRANCAIS DE CHIRURGIE - PARIS - 23 au 26 septembre 1985 29. Kestens P.J., Gianello P. et Lambotte L. Expérience du pancréas artificiel dans les tumeurs endocrines. SOCIETE BELGE DE GASTRO-ENTEROLOGIE - BRUXELLES - Octobre 1985 30. Gigot J.F., Gianello P., Verhelst B., Reynaert M., Otte J.B. et Kestens P.J. Shunts péritonéoveineux pour Ascite Réfractaire chez le patient cirrhotique. IIème CONGRES DE L'E.S.O.T. - MUNICH - 27 au 29 novembre 1985 31. Gianello P., Squifflet J.P., Pirson Y., Leclercq B., Jamart J., Latinne D. and Alexandre G.P.J. One Haplotype Matched Living Related Donor Transplantation Analysis of 5 successive Protocols. SOCIETE ROYALE BELGE DE GASTRO-ENTEROLOGIE. BRUXELLES - 1 mars 1986. 32. Gigot JF, Gianello P, Dardenne A, Detry R, Otte JB, Kestens PJ. Apport de de l'échographie peropératoire dans la chirurgie du pancréas endocrine et exocrine: résultats préliminaires. Xèmes JOURNEES FRANCOPHONES D'HEPATOLOGIE ET DE GASTROENTEROLOGIE - NICE - 10 au 14 mars 1986 33. Gianello P., Lerut J., Otte J.B. et Kestens P.J. La chirurgie de la pancréatite chronique : Resection versus drainage. Suivi à long terme de 100 patients opérés. 34. Gianello P., Squifflet J.P., Pirson Y., Alexandre G.P.J. et Kestens P.J. Attitude thérapeutique face aux complications digestives dans une population à haut risque : A propos de 812 transplantations rénales. 35. Gianello P., Lerut J., Otte J.B. et Kestens P.J. La duodéno-pancréatectomie céphalique : Evaluation des facteurs de risques chez 114 patients. 30 36. Gigot JF, Gianello P, Dardenne A, Otte JB, Kestens PJ. L'échographie peropératoire dans la chirurgie du pancréas endocrine: résultats préliminaires à propos de 6 insulinomes. CONGRES BELGE DE CHIRURGIE - BRUXELLES - Avril 1986 37. Gianello P., Squifflet J.P., Reynaert M., Pirson Y., Kestens P.J. et Alexandre G.P.J. Poster : Les complications digestives en Transplantation rénale. - A propos de 812 greffes rénales. XI INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY HELSINKI - 3 au 8 août 1986 38. Gianello P., Squifflet J.P., Pirson Y., Stoffel M. and Alexandre G.P.J. Poster: Ciclosporin A plus low dose steroids versus conventional therapy in cadaver kidney transplant : A randomized trial. 9th WORLD CONGRESS OF THE COLLEGIUM INTERNATIONAL CHIRUGIAE DIGESTIVAE (C.I.C.D.) - JERUSALEM - 31 august to 5 september 1986 39. Gianello P., Squifflet J.P., Pirson Y., Carlier M., Vandeleene B., Reynaert M. and Alexandre G.P.J. Nine Human pancreas transplants : Results and Management. 40. Gigot J.F., Gianello P., Dardenne A., Lambotte L., Otte J.B. and Kestens P.J. Pre and Intraoperative localization of a series of 21 insulinoma patients. 41. Gigot J.F., Gianello P., Dardenne A.N., Detry R., Otte J.B. and Kestens P.J. Poster : Intraoperative Ultrasound in Biliary and Pancreatic Tumors. 42. Lambotte L., Salliez A., Gianello P., Otte J.B. and Kestens P.J. Increased Sensitivity of glucose monitoring during insulinoma surgery. 43. Gianello P., Lerut J., Gigot J.F., Otte J.B. and Kestens P.J. Anevrysms of the branches of the coeliac axis. LYON - 14 - 15 novembre 1986 - SYMPOSIUM : " La survie à long terme de l'insuffisance rénale chronique et transplantation". 44. Gianello P., Pirson Y., Squifflet J.P. et Alexandre G.P.J. Analyse multifactorielle de la survie à long terme de 419 greffés rénaux. SOCIETE FRANCAISE DE CHIRURGIE DIGESTIVE - TOULOUSE - 5/12/86 45. Gigot JF, Gianello P, Dereme T, Detry R, Otte JB, Kestens PJ. Apport de l'échographie peropératoire en chirurgie tumorale bilio-pancréatique. 31 SOCIETE ROYALE BELGE DE RADIOLOGIE - BRUXELLES- 13/12/86. 46. Gigot JF, Gianello P, Dereme T, Detry R, Otte JB, Kestens PJ. L'échographie dans les tumeurs bilio-pancréatiques. JOINT MEETING OF GASTROENTEROLOGY - BRUSSELS - 20 to 21 february 1987 47. Gianello P., Gigot J.F., Dardenne A.N., Lambotte L., Rahier J., Otte J.B. and Kestens P.J. Pre- and intraoperative localization of insulinomas : report of 22 observations. 48. Van Vyve E., Gigot J.F., Gianello P., Reynaert M., Pringot J., Otte J.B. and Kestens P.J. Retroperitoneal laparotomy in the treatment of infected necrosis following acute necrotic pancreatitis. 49. Gigot J.F., Gianello P., Dereme T., Detry R., Otte J.B. and Kestens P.J. Intraoperative ultrasonography : a usefull method in liver surgery. 50. Gianello P., Gigot J.F., Dereme T., Pringot J., Otte J.B. and Kestens P.J. Poster :The role of intraoperative investigations in the surgery of chronic pancreatitis. 51. Gigot J.F., Labaki L., Gianello P., Detry R., Otte J.B. and Kestens P.J. Poster : Segmental portal hypertension in chronic pancreatitis. SEMAINE FRANCOPHONE DE PATHOLOGIE DIGESTIVE -PARIS- 28 février au 4 mars 1987 52. Gianello P., Gigot J.F., Dardenne A., Lambotte L., Dereme T., Rahier J., Otte J.B. et Kestens P.J. Valeur prédictive des examens pré- et per-opératoires dans la localisation des insulinomes. 53. Gigot J.F., Gianello P., Dereme T., Dardenne A., Detry R., Otte J.B. et Kestens P.J. Apport de l'échographie peropératoire en chirurgie tumorale bilio-pancréatique. 54. Gigot J.F., Gianello P., Dereme T., Pringot J., Otte J.B. et Kestens P.J. Apport des investigations radiologiques pré- et peropératoires la chirurgie de la pancréatite chronique. 55. Van Vyve E., Reynaert M., Gianello P., Gigot J.F., Otte J.B. et Kestens P.J. La laparostomie rétropéritonéale dans le traitement des nécroses infectées sur pancréatite aiguë sévère. 56. Gigot J.F., de Neve de Roden A., Gianello P., Dereme T., Detry R., Therasse G., Otte J.B. et Kestens P.J. Apport de l'échographie peropératoire en chirurgie cancérologique digestive. 32 SOCIETE BELGE DE PHYSIOLOGIE ET DE PHARMACOLOGIE FONDAMENTALES ET CLINIQUES -LIEGE - 21 mars 1987 57. Gianello P., Ramboux A., Poelaert D., Squifflet J.P., Carlier M., Donckier J., Ketelslegers J.M., Lambotte L. et Alexandre G.P.J. Effets bénéfiques de l'hormone natriurétique cardiaque sur la fonction rénale immédiate après ischémie par clampage chez le rat. ABO INCOMPATIBILITY IN TRANSPLANTATION - PHILADELPHIE - 29 to 31 march 1987 58. Alexandre G.P.J., Squifflet J.P., De Bruyere M., Latinne D., Reding R., Gianello P., Carlier M. and Pirson Y. Present experience in a serie of 26 ABO-Incompatible Living Donor Renal Allografts. 14TH BELGIAN COUNCIL FOR LABORATORY ANIMAL SCIENCE - BRUSSELS ATTITUDE OF RESEARCHER FACED WITH EXPERIMENTATION - 30 April 1987 59. Gianello P. Expérimentation animale en transplantation rénale; existe-t-il une alternative ? SANDIMMUM IN ORGAN TRANSPLANTATION - GENVAL - 9 mai 1987 60. Squifflet J.P., Gianello P., Stoffel M. and Alexandre G.P.J. Ciclosporin A plus low dose steroids versus conventional therapy in cadaver kidney transplantation : analysis of a randomized trial at three year. CONGRES BELGE DE CHIRURGIE - BRUSSELS - 9 mai 1987 61. Collard J.M., Gianello P., Fiasse R., Otte J.B. et Kestens P.J. La chirurgie du reflux gastrooesophagien. HEPATO-PANCREATO-BILIARY SURGERY Course and Conference: LUND, 15-19 june 1987 62. Gianello P., Gigot J.F., Dereme T., Pringot J., Otte J.B. and Kestens P.J. Poster : The role of intraoperative investigations in the surgery of chronic pancreatitis. 63. Gigot J.F., Labaki L., Gianello P., Detry R., Otte J.B. and Kestens P.J. Poster : Segmental portal hypertension in chronic pancreatitis. DEUXIEME SYMPOSIUM INTERNATIONAL SUR TRANSPLANTATIONS - MARSEILLE - 15 au 17 juin 1987 LES GREFFES ET 64. Alexandre G.P.J., Squifflet J.P., De Bruyere M., Latinne D., Reding R., Gianello P., Carlier M. and Pirson Y. Present experience of a serie of 26 ABO incompatible living donor renal allografts. 33 65. Gianello P., Ramboux A., Poelaert D., Squifflet J.P., Carlier M., Donckier J., Ketelslegers J.M., Lambotte L. et Alexandre G.P.J. Effets bénéfiques de l'hormone natriurétique cardiaque sur la fonction rénale immédiate après ischémie par clampage chez le rat. 66. Gianello P., Squifflet J.P., Stoffel M. et Alexandre G.P.J. Ciclosporin A + low dose steroids versus conventional therapy in cadaver kidney. COLLEGE INTERNATIONAL DES CHIRURGIENS - STRASBOURG - 19 au 20 juin 1987 67. Gianello P., Gigot J.F., Pringot J., Otte J.B. et Kestens P.J. Apport des investigations radiologiques pré- et peropératoires dans la chirurgie de la pancréatite chronique. SYMPOSIUM CHIRURGIE ENDOCRINE-FONDATION MERIEUX: LYON - 21 novembre 1987 68. Gianello P., Mathieu L., Latinne D., Rahier J., Squifflet J.P. et Alexandre G.P.J. Les allogreffes parathyro,oïdiennes humaines. THIRD INTERNATIONAL CONGRESS OF ORGAN PROCUREMENT - BARCELONE 2 to 4 December 1987 69. Gianello P., Janssens T., Chatzopoulos C., Kartheuser A., Lambotte L., Squifflet J.P. and Alexandre G.P.J. Beneficial effect of Piracetam on renal blood flow in ischemically injured kidneys in the rat. 70. Gianello P., Poelaert D., Ramboux A., Squifflet J.P., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L. and Alexandre G.P.J. Beneficial effect of "Atrial Natriuretic Factor" on ischemically injured kidneys in the rat. 71. Gianello P., Squifflet J.P., Carlier M., Jamart J., Pirson Y, Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L. and Alexandre G.P.J. Beneficial effect of maximal hydration on early renal function after ischemia is mediated by Atrial Natriuretic factor. EUROPEAN SOCIETY OF SURGICAL RESEARCH - BOLOGNE - 2 to 5 May 1988 72. Gianello P., Janssens T., Chatzopoulos C., Kartheuser A., Lambotte L., Squifflet J.P. and Alexandre G.P.J. Beneficial effect of Piracetam on renal blood flow in ischemically injured kidneys in the rat. 73. Gianello P., Squifflet J.P., Carlier M., Jamart J., Mahy B., Pirson Y., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L. and Alexandre G.P.J. Is Atrial Natiuretic Factor the humoral factor by which volume loading or Mannitol infusion produces an improved renal function recovery after ischemia ? 34 26ème JOURNEE DE CHIRURGIE HEPATO-BILIAIRE - PARIS 18-21 MAY 1988 74. Gigot JF, Gianello P, Fiasse R, Dardenne A, Pringot J, Rahier J, Otte JB, Kestens PJ. Les tumeurs endocrines du pancréas: approche diagnostique et thérapeutique. SECOND WORLD CONGRESS ON HEPATO-PANCREATO-BILIARY SURGERY, AMSTERDAM - 2 JUNE 1988. 75. Gigot JF, Gianello P, Van Beers B, Pringot J, Dardenne A, Otte JB, Kestens PJ. The role of intraoperative investigations in the surgery of chronic pancreatitis. AMERICAN SOCIETY OF TRANSPLANT SURGEONS - CHICAGO - 3 to 5 June 1988 76. Gianello P., Ramboux A., Poelaert D., Jamart J., Berbinschi A., Donckier J., Ketelslegers J.M., Lambotte L., Squifflet J.P. and Alexandre G.P.J. Atrial Natriuretic Factor prevents acute Ciclosporine Nephrotoxicity after ischemia in the rat. XII INTERNATIONAL CONGRESS OF THE TRANSPLANT SOCIETY - SIDNEY 14 to 19 August 1988 77. Gianello P., Janssens T., Chatzopoulos C., Kartheuser A., Lambotte L., Squifflet J.P. and Alexandre G.P.J. Beneficial effect of Piracetam on renal blood flow in ischemically injured kidneys in the rat. 78. Gianello P., Squifflet J.P., Carlier M., Jamart J., Mahy B., Pirson Y., Berbinschi A., Donckier J., Kestelslegers J.M., Lambotte L. and Alexandre G.P.J. Is Atrial Natriuretic Factor the humoral factor by which volume loading or Mannitol infusion produces an improved renal function recovery after ischemia ? 79. Gianello P., Ramboux A., Poelaert D., Jamart J., Berbinschi A., Donckier J., Kestelslegers J.M., Lambotte L., Squifflet J.P. and Alexandre G.P.J. Atrial Natriuretic Factor prevents acute Ciclosporine Nephrotoxicity after ischemia in the rat. XIX INTERNATIONAL CONGRESS OF INTERNAL MEDICINE - BRUXELLES - 15 Août 1988 80. Donckier J., Gianello P., Berbinschi A., Squifflet J.P., Carlier M. and Kestelslegers J.M. Renal metabolism of Atrial Natriuretic factor in and stage renal failure. X WORLD CONGRESS OF THE COLLEGIUM INTERNATIONALE CHIRURGIAE DIGESTIVAE - COPENHAGEN - 31 AUGUST 1988. 81. Gigot JF, Gianello P, Van Beers B, Pringot J, Dardenne A, Otte JB, Kestens PJ. The role of intraoperative investigations in the surgery of chronic pancreatitis. 35 10Th ANNUAL MEETING OF THE INTERNATIONAL HEPATO-BILIARYPANCREATIC ASSOCIATION - NICE - 13 SEPTEMBER 1988. 82. Gigot JF, Gianello P, Van Beers B, Pringot J, Dardenne A, Otte JB, Kestens PJ. The role of intraoperative investigations in the surgery of chronic pancreatitis. 83. Gigot JF, Gianello P, Pringot J, Dardenne A, Lambotte L, Otte JB, Kestens PJ. Pre and intraoperative localization of a series of 22 insulomas patients. GEZAMENLIJKE VERGADERING-NEDERLANDSE VEREINING VOOR HEELKUNDE EN KONINKLIJK BELGISH GENOOTSHAP VOOR HEELKUNDE AMSTERDAM - 23 OCTOBER 1988. 84. Kestens PJ, Otte JB, de Hemptinne B, Gigot JF, Gianello P. State of the art on hepato-biliopancreatic surgery. PROGRES RECENTS EN GASTRO-ENTEROLOGIE - BRUXELLES - 21 au 22 octobre 1988 85. Gianello P., Gigot J.F., Mourad M., Blouard E., Fernez P., Dive Ch., Otte J.B. et Kestens P.J. Résultats du traitement chirurgical de la pancréatite chronique. Etude rétrospective de 128 patients. 86. Gigot J.F., Gianello P., Dive Ch., Prignot J., Otte J.B. et Kestens P.J. Apport des investigations pré- et per-opératoires dans l'élaboration d'un traitement chirurgical de la pancréatite chronique. XXIVth CONGRESS OF THE EUROPEAN SOCIETY FOR SURGICAL RESEARCH 28 to 31 May 1989 - BRUSSELS 87. Gianello P. Workshop "Microcirculation" 31 may 89. Improvement of microcirculation in ischemically injured kidneys. 2nd INTERNATIONAL CONGRESS ON PANCREATIC TRANSPLANTATION - 20 to 22 September 1989, MINNEAPOLIS AND ISLET 88. Squifflet J.P., Gianello P., Pirson Y., Jamart J., Reynaert M., Van Obbergh L. and Alexandre G.P.J. Segmental pancreatico jejunostomy versus whole pancreatico-duodenocystostomy for human pancreas transplantation. Formation post-graduée en endocrinologie et nutrition - 29 septembre 89 -BRUSSELS. 89. Gianello P. L'A.N.F. dans la greffe rénale et chez le patient sous cyclosporine. Perspectives thérapeutiques. 36 INTERNATIONAL COLLEGE OF SURGEONS - ANTWERPEN - 29 au 30 septembre 1989 90. Gigot J.F., Kestens P.J., Gianello P., Pringot J., Dardenne A., Mathurin P., Charlier M., Lambert A.E., Lambotte L. L'Insulinome. 91. Squifflet J.P., Gianello P., Pirson Y., Vandeleene B., Reynaert M. and Alexandre G.P.J. Transplantation pancréatique : expérience clinique. IVth CONGRESS OF THE EUROPEAN SOCIETY FOR ORGAN TRANSPLANTATION -BARCELONA -1 to 4 November 1989 92. Squifflet J.P., De Hemptinne B., Gianello P., Balladur P., Otte J.B. and Alexandre G.P.J. A new technique for "en-bloc" liver and pancreas harvesting. JOURNEE SCIENTIFIQUE "HYGIENE HOSPITALIERE" 10 Novembre 1989 - ECOLE DE SANTE PUBLIQUE - U.C.L. - BRUXELLES 93. Gianello P. et Lamy M. Transplantation rénale et C.M.V. 83ème CONGRES FRANÇAIS D'UROLOGIE - PARIS - 15-17 NOVEMBRE 1989. 94. Caramuta V., Squifflet J.P., Gianello P., Wese F.X., Opsomer R.J. et Alexandre G.P.J. Résultats de la transplantation rénale dans les uropathies malformatives. DIPLOME D'ETUDE APPROFONDIE DE TRANSPLANTATION - PARIS - HOPITAL COCHIN, AVRIL 1990. 95. Gianello P. L'ischémie rénale et la reperfusion post-ischémique. ENSEIGNEMENT INTERUNIVERSITAIRE D'ENDOCRINOLOGIE. FNRS ET SOCIETE BELGE D'ENDOCRINOLOGIE. BRUXELLES 4 MAI 1991 96. P.Gianello, A Berbinschi, JP Squifflet, M Carlier, GPJ Alexandre. ANF et Endotheline dans l'ischémie rénale aigue et la transplantation rénale. CONGRES BELGE DE CHIRURGIE ENDOCRINIENNE, PANCREATIQUE ET SURRENALIENNE - BRUXELLES - 5 MAI 1990. 97. Squifflet J.P., Gianello P., Alexandre G.P.J. Etat actuel de la transplantation pancréatique. SOCIETY FOR ORGAN SHARING. ROME - JUIN 1991. 98. D Latinne, M Moriau, M Carlier, Y Pirson, C Lecomte, JP Squifflet, P.Gianello. Human ABO-incompatible kidney transplantation. 37 FIRST INTERNATIONAL CONGRESS ON XENOTRANSPLANTATION. MINNEAPOLIS 25-28 AUGUST 1991. 99. P Gianello, D Latinne, JP Squifflet, M Carlier, L Lambotte, GPJ Alexandre. Long term survival in discordant renal xenotransplantation. ENSEIGNEMENT INTERUNIVERSITAIRE D'ENDOCRINOLOGIE. BRUXELLESSEPTEMBRE 1991. 100. P.Gianello. L'hyperparathyroidie. Le cancer médullaire de la thyroide. INTERNATIONAL CONGRESS OF TRANSPLANTATION : PARIS-AUGUST 1992. 101. JF. Fishbein, Gianello P. Interleukin-2 reverses the ability of cyclosporine to induce tolerance to class I disparate kidney allografts in miniature swine. 102. D.Latinne, Gianello P. Xenotransplantation from pig to monkey: an approach toward tolerance induction. XENOGRAFT MEETING: ANNECY-MARCH 1993 103. T.Besse, L.Duck, D.Latinne, P.Gianello, J.P.Squifflet, M.Lievens, J.P. Tomasi, E.M. Lavenne-Pardonge, L.Lambotte, G.P.J Alexandre, H.Bazin. Effect of plasmapheresis and splenectomy on parameters involved in vascular rejection of discordant xenografts in the swine to baboon model. II INTERNATIONAL CONGRESS ON XENOTRANSPLANTATION : CAMBRIDGESEPTEMBER 26-29 1993. 104. Tanaka M, Latinne D, Gianello P et al : Xenotransplantation from pig to cynomolgus monkey: the potential for overcoming xenograft rejection trough induction of chimerism. 105. Powelson J, Cosimi AB, Austen W Jr, Bailin M, Colvin R, Gianello P et al : Porcine to primate orthotopic liver transplantion. LILLY CONFERENCE ON XENOTRANSPLANTATION: PARIS-OCTOBER 12 1993. 106. P Gianello. Elimination of preformed xenoantibodies. AMERICAN SOCIETY OF TRANSPLANT PHYSICIANS: CHICAGO-MAY 16-18, 1994 107. Sablinski T, Smith CV, Gianello P, Fishbein JM, Foley A, Nickeleit V, Colvin RB, Sachs DHS.: Tolerance to fully MHC mismatched renal allografts in chimeric swine. AMERICAN SOCIETY OF TRANSPLANT SURGEONS: CHICAGO-MAY 18-20, 1994 108. Gianello P, Blancho G, Fishbein JM, Lorf T, Vitiello D, Sachs DHS. Mechanism of Cyclosporin-induced tolerance to primarily vascularized renal allografts in miniature swine. 38 109. Powelson J, Cosimi AB, Austen W, Bailin M, Colvin R, Eason J, Gianello P, Kawai T, Tanaka T, Sablinski T, Sachs DHS. Kidney and liver xenotransplantation from pig to monkey. XVth WORLD CONGRESS OF THE TRANSPLANTATION SOCIETY: KYOTOAUGUST 28 - September 2, 1994. 110. Gianello P., Blancho G., Fishbein J., Lorf T., Nickeleit V., Vitiello D., Arn J.S, Leguern C., Sachs D.H. Mechanism of Cyclosporine-induced tolerance to primarily vascularized allografts in miniature swine. 111. Sablinski T., Emery DW., Gianello P., Shimada H., Lorf T., Foley A., Nickeleit V., Arn S., Colvin R., Leguern C., Sachs DHS. Induction of transplantation tolerance in miniature swine through allogenic MHC gene transfer. 112. Sachs DHS., Sablinski T., Arn S.J., Bailin M., Colvin R., Eason J., Gianello P., Kawai T., Lorf T., Nickeleit V., Powelson J., Sykes M., Tanaka M., Cosimi A.B. Pig to monkey kidney xenotransplantation by a mixed chimerism approach. 113. Giangrande I., Gianello P., Lorf T., Vitiello D., Leguern C., Sachs DHS. Humoral response of miniature swine tolerant to class I mismatched renal allografts. SOCIETE FRANCAISE DE TRANSPLANTATION : PARIS, DECEMBER 1-2, 1994. 114. Gianello P., Blancho G., Fishbein J., Lorf T., Vitiello D., Nickeleit V., Sachs DH. Tolérance spécifique et définitive à une allogreffe de rein au travers d’une incompatibilité d’antigènes de classe 1 : étude des mécanismes de tolérance chez le porc miniature. Symposium on "TOLERANCE INDUCTION": COLORADO, JANUARY 22-25, 1995 115. Sablinski T., Emery DW., Gianello P., Shimada H., Lorf T., Foley A., Nickeleit V., Arn S., Colvin R., Leguern C., Sachs DH. Genetic engineering approach to transplantation tolerance in miniature swine. AMERICAN SOCIETY OF TRANSPLANT SURGEONS: CHICAGO, MAY, 17-19, 1995. 116. Gianello P., Yamada K., Fishbein J., Lorf T., Nickeleit V., Sachs DH. Long term acceptance of primary vascularized renal allografts in miniature swine involves systemic tolerance and does not require graft adaptation. SOCIETE FRANCAISE D'EXPERIMENTATION ANIMALE : PARIS, JUNE 14-16, 1995. 117. Gianello P. Modèles porcins et xénogreffes XIII INTERNATIONAL CONGRESS OF NEPHROLOGY : MADRID, JULY 2-6, 1995. 118. Gianello P., Carlier M., Jamart J., Hulhoven R., Bernheim J., Ketelslegers JM., Bernard A., 39 Squifflet JP. Effect of atrial natriuretic peptide (ANP) on acute renal failure in cadaveric renal transplantation. 4TH BASIC SCIENCES SYMPOSIUM OF THE TRANSPLANTATION SOCIETY. LEIDEN, SEPTEMBER 17-20, 1995. 119. Gianello P., Blancho G., Fishbein J., LeGuern C., Sachs DH. Mechanism of tolerance to primarily vascularized allografts in miniature swine. 120. Blancho G., Gianello P., Germana S., Sachs DH., LeGuern C. Cytokine expression in a model of tolerance to a renal allograft in miniature swine. THE THIRD INTERNATIONAL CONGRESS FOR XENOTRANSPLANTATION. BOSTON, SEPTEMBER 27-OCTOBER 1, 1995 121. Sablinski T., Gianello P., Lorf T., Emery D., Bailin M., Meehan S., Monroy R., Colvin R., Cosimi A., Sachs D. Pig to monkey kidney transplantation. 122. Sablinski T., Lorf T., Monroy R., Bailin M., Gianello P., Cosimo A., Sachs D. Absorption of preformed primate anti-swine antibodies by extracorporeal perfusion through Gal α(1,3) Gal columns. 123. Havaux X., Hori S., Soares M., Gianello P., Latinne D., Bazin H. Clearance of IgM and antiμ immune complexes by kupffer cells in rats treated with anti-μ monoclonal antibodies. 124. Sablinski T., Emery D., Hawley B., Monroy R., Gianello P., Lorf T., Bailin M., Cosimi A., Sachs D. Long-term discordant xenogeneic (porcine to primate) bone marrow chimerism in a monkey treated with porcine-specific stem cell factor and IL-3. SOCIETE FRANCAISE DE TRANSPLANTATION: PARIS, NOVEMBER 30 DECEMBER 1, 1995. 125. Gianello P., Carlier M., Jamart J., Ketelslegers JM., Bernard A., Squifflet JP. Effet de l’Hormone Natriurétique Cardiaque (HNC) sur l’incidence de la nécrose tubulaire aigüe (NTA) en transplantation rénale à partir de rein de cadavre. JAPANESE SOCIETY OF SURGERY, TOKYO, APRIL 10-12, 1996. 126. Gianello P., Blancho G., Fishbein J., LeGuern C., Sachs DH. Mechanism of tolerance to primarily vascularized allografts in miniature swine XV AMERICAN SOCIETY OF TRANSPLANT PHYSICIANS, DALLAS, MAY 1996. 127. Yamada, K., Gianello, P., Ierino,F., Shimizu, A., Meehan S., Colvin R., Sachs D.H. Influence of the thymus on transplantation in miniature swine. 128. Yamada, K., Gianello,P., Fishbein, J., Lorf, T., Shimizu A., Colvin R., Sachs, D.H. Steroid 40 administration intereferes with the induction of transplant tolerance by cyclosporine. 8ème JOURNEE DE BICETRE - PARIS, JUNE 6 1996 129. Gianello P., Squifflet JP. Faut-il reperfuser les reins avant de les greffer? UNIVERSITY OF GöTTINGEN - 2 JULY 1996 130. Gianello P. ABO-incompatible living related kidney transplantation: experience at UCL. XVI INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY BARCELONA, August 25-30, 1996. 131. Yamada K., Gianello P., Ierino F., Shimizu A., Meehan S., Colvin R., Sachs D. Influence of the thymus on transplantation tolerance in miniature swine. 132. Leguern C., Emery D., Sablinski T., Gianello P., Yasumoto A., Shimada H., Germana S., Sonntag K.C., Arn S., Sachs D. Gene therapy of immune tolerance in a preclinical model. THE 4TH INTERNATIONAL CONGRESS FOR XENOTRANSPLANTATION- NANTES, September 7-11, 1997. 133. Xu,Y., Awwad, M., Kozlowski T., Ierino,F., Lorf T., Sablinski T., Latinne D., Gianello P., Cooper DKC., Sachs, DH. Prevention of sensitization to new antigen specificities in non-human primates exposed to porcine antigens. 134. Delrivière L., Havaux X., Gianello P., Gibbs P. Orthotopic liver transplantation from guinea pig to rat is not a usable model because of fundamental anatomico-physiological differences between the species. BELGIAN COUNCIL FOR LABORATORY ANIMAL SCIENCE DIEPENBEEK, October 3, 1997. 135. P.Gianello: The use of transgenic animals for xenotransplantation. AMERICAN SOCIETY OF TRANSPLANT SURGEONS: CHICAGO, May, 13-15, 1998. 136. P.Gianello, S.Hori, JP Dehoux., S Talpe, F Cormont, H Bazin, D.Latinne. In baboon, a complete elimination of the circulating IgM by anti-μ monoclonal antibody allows a pig kidney xenograft to survive up to six days without additional immunosuppression. XVII INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY MONTREAL July 12-17, 1998. 137. F.Oike, S Talpe, M.Otsuka, JP Dehoux, J Lerut, JB Otte, P.Gianello. A twelve day course of FK506 allows long term acceptance of semi-identical liver allograft in inbred miniature swine. 41 138. JP Dehoux, P.Gianello, S.Hori, JP Dehoux., S Talpe, F Cormont, H Bazin, D.Latinne. In baboon, a complete elimination of the circulating IgM by anti-μ monoclonal antibody allows a pig kidney xenograft to survive up to six days. 139. JP Dehoux, N Dewolf, S Talpe, F Cormont, M Otsuka, F Oike, D Latinne, H Bazin, P Gianello. In vitro and in vivo effects on both human and nonhuman primate allogeneic response of a new rat anti-CD2 monoclonal antibody (LO-CD2b). (Poster) ASPECTS SCIENTIFIQUES ET SOCIO-CULTURELS DES XENOGREFFES. PARIS October 29-30, 1998. 140. P.Gianello. Aspects scientifiques des essais cliniques. PREMIERES JOURNEES DE CHIRURGIE DE NOVEMBRE. BRUSSELS, November 20,1998. 141. P.Gianello. Existe-il un avenir pour les xénogreffes? SIXTH MEETING OF THE EUROPEAN WORKING GROUP ON HUMAN GENE TRANSFER AND THERAPY. JERUSALEM, November 21-24, 1998 142. M. Otsuka, P. Gianello, I. Nur, M.Baru. In vivo gene transfer by liposome-encapsulated DNA into liver following transplantation, resection and ischemia. BELGIAN TRANSPLANTATION SOCIETY, LEUVEN, March 13, 1999. 143. O. Ciccarelli, E. Mauel, R. Gheerardyn, P.F. Laterre, F. Roggen, P. Gianello, V. Van Leeuw, J.B. Otte, J.P. Lerut. Steroid withdrawal and adult liver transplantation (LT). AMERICAN SOCIETY OF TRANSPLANTATION. CHICAGO May, 15-19, 1999. 144. J.Lerut,PF Laterre, O.Cicarelli, F.Roggen, B.Fraipont, S.Talpe, C.Sempoux, P.Gianello, JB Otte, J.Hope, H.Bazin, D.Latinne. The use of tacrolimus and anti-CD2 antibody LO-CD2a in adult liver transplantation: preliminary results of a prospective randomized study. 145. K.Yamada, J.Fishbein, P.Gianello,F.Ierino, A.Shimizu, B.Colvin, D.H.Sachs. Influence of the thymus on sensitization and the requirment of antigen for the maintenance of tolerance to renal allografts in miniature swine. 146. J.Lerut, E.Mauel, R.Ghererardyn, O.Cicarelli, PF.Laterre, F.Roggen, P.Gianello, V.Van leeuw, JB Otte. Adult liver transplantation: steroid withdrawal ...and even more. 4-years results of a prospective study. AMERICAN SOCIETY OF TRANSPLANT SURGEON. CHICAGO, May, 19-21,1999. 147. M.Otsuka, M.Baru, I.Nur, P.Gianello. DNA gene transfer into rat and pig liver by liposomal vector. 42 148. F.Oike, S.Talpe, M.Otsuka, JP Dehoux, J.Lerut, JB Otte, P.Gianello. A twelve day course of FK506 allows long term acceptance of semi-identical liver allograft in inbred miniature swine. EUROPEAN CONGRESS OF TRANSPLANTATION. OSLO, June 19-24, 1999 149. M.Otsuka, M.Baru, I.Nur, P.Gianello. DNA gene transfer into rat and pig liver by liposomal vector. 150. F.Oike, S.Talpe, M.Otsuka, JP Dehoux, J.Lerut, JB Otte, P.Gianello. A twelve day course of FK506 allows long term acceptance of semi-identical liver allograft in inbred miniature swine. 151. JP Dehoux, S.Hori, S Talpe, F Cormont, H Bazin, D.Latinne, P.Gianello. In baboon, the complete elimination of the circulating IgM by anti-μ monoclonal antibody allows a pig kidney xenograft to survive up to six days. 152. JP.Dehoux, S.Talpe, D.Latinne, H.Bazin, P.GIanello. Effect of a new rat monoclonal antibody which recognizes the CD2 in both human and non-human primates. 153. JP Dehoux, M Otsuka, S Talpe, F Cormont, F Oike, Della Parra B, H. Bazin, D Latinne, P Gianello. In vitro and in vivo effects on both human and nonhuman primate allogeneic response of a new rat anti-CD2 monoclonal antibody (LO-CD2b). (Poster) V. CONGRESS OF XENOTRANSPLANTATION. NAGOYA, October 24-28, 1999 154. JP Dehoux, S.Hori, S Talpe, H Bazin, D.Latinne, P.Gianello. In baboon, a complete elimination of the circulating IgM by anti-μ monoclonal antibody allows a pig kidney xenograft to survive up to six days. POSTRANSPLANT IMMUNOSUPPRESSION: NEW PARADIGMS MINNEAPOLIS, October 20-23,1999. 155. F.Oike, S.Talpe, M.Otsuka, JP Dehoux, J.Lerut, JB Otte, P.Gianello. A twelve day course of FK506 allows long term acceptance of semi-identical liver allograft in inbred miniature swine. ANNUAL MEETING OF THE BELGIAN TRANSPLANTATION SOCIETY. LIEGE, April 1, 2000. 156. F.Oike, S.Talpe, M.Otsuka, JP Dehoux, J.Lerut, JB Otte, P.Gianello. A twelve day course of FK506 allows long term acceptance of semi-identical liver allograft in inbred miniature swine. 157. JP Dehoux, S.Hori, S Talpe, H Bazin, D.Latinne, P Gianello. In baboon, the specific elimination of circulating IgM by anti-μ monoclonal antibody allows a pig kidney xenograft to survive up to six days. 43 XVIII INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY. ROME, August 27 - September 1, 2000. 158. J Lerut, S Talpe, F Roggen, R Gheerardyn, O Ciccarelli, PF Laterre, JB Otte, J Hope, H Bazin, P Gianello, D Latinne. One year results of tacrolimus (TAC) and anti-CD2 antibody (BTI322) in adult liver transplantation (LT). 159. JP Dehoux, B de la Parra, D Latinne, H Bazin, JP Squifflet, P Gianello. Identification of αgalactosyl epitopes on rat monoclonal antibodies and assessment of the anti-galactosyl human or nonhuman primate response. 160. Lerut, J., Talpe, S. Gheeradyn, R., Roggen, F., Ciccarelli, O., Laterre P.F., Otte, J.B., Hope, J., Latinne, D., Rahier, J., Gianello, P. The "seven-up" score in adult liver transplantation (LT): An easy tool to define the real need of allograft rejection treatment. 161. V Donckier, J Closset, O Le Moine, N Nagy, E Quertinmont, S Narula, M Goldman, J Devière, M Gelin, P Gianello. Interleukin-10 attenuates ischemia-reperfusion injury in liver transplantation in pig. WORLD CONGRESS ON LUNG HEALTH AND 10TH ERS ANNUAL CONGRESS, FLORENCE, August 30 - September 3, 2000. 162. P Gianello. Xenografting. INTERNATIONAL SYMPOSIUM ON TOLERANCE INDUCTION TO VASCULARIZED ALLOGRAFTS, BRUSSELS, October 28, 2000. 163. P Gianello. Tolerance to vascularized allograft in inbred miniature swine model. THE EUROPEAN MEDICAL SCIENTIFIC SYMPOSIUM TRANSPLANTATION, AMSTERDAM, November 11-12, 2000. ON ORGAN 164. P. Gianello. Xenotransplantation. 8TH UNITED EUROPEAN GASTROENTEROLOGY WEEK, BRUSSELS, November 2530, 2000. 165. P. Gianello. The future of xenotransplantation. MEETING AT CAMBRIDGE UNIVERSITY, Addenbrokers Hospital, December 14, 2000. 166. P Gianello. Tolerance to vascularized allograft in inbred miniature swine model. 44 IIIème CONGRES DE LA SOCIETE FRANCOPHONE DE RECHERCHE CLINIQUE ET BIOLOGIQUE EN TRANSPLANTATION, GENEVE, December 14 - 16, 2000 167. JP Dehoux, S Hori, S Talpe, H Bazin, D Latinne, P Gianello. L’élimination des anticorps préformés d’isotype IgM, et non d’isotype IgG, permet à une xénogreffe rénale porcine de survivre chez le babouin plus de 6 jours sans immunosuppression. 168. JP Dehoux, B de la Parra, D Latinne, H Bazin, JP Squifflet, P Gianello. Human and nonhuman primate anti-Galactosyl response after injection of rat mAb bearing Galactosyl epitopes. (Poster) BELGIAN TRANSPLANTATION SOCIETY, BRUSSELS, March 17, 2001. 169. JP Dehoux, B de la Parra, D Latinne, H Bazin, P Gianello. Effect in vitro and in vivo of a rat anti-CD2 monoclonal antibody (LO-CD2b) on pig to baboon xenogeneic cellular (T and Natural Killer cells) immune response. SOCIETE ROYALE BELGE DE GASTRO-ENTEROLOGIE, PRESIDENT, BRUSSELS, June 2, 2001. JOURNEE DU 170. P Gianello. Tolérance immunologique et transplantation hépatique. VI CONGRESS OF THE INTERNATIONAL XENOTRANSPLANTATION ASSOCIATION, CHICAGO, September 29 - October 3, 2001. 171. JP Dehoux, B de la Parra, D Latinne, H Bazin, JP Squifflet, P Gianello. Human and nonhuman primate anti-Galactosyl response after injection of rat mAb bearing Galactosyl epitopes. (Poster) 172. JP Dehoux, B de la Parra, D Latinne, H Bazin, P Gianello. Characterization of baboon antiporcine IgG antibodies after rat anti-μ monoclonal antibody treatment. (Poster) 173. JP Dehoux, B de la Parra, D Latinne, H Bazin, P Gianello. Effect in vitro and in vivo of a rat anti-CD2 mAb on pig to baboon xenogeneic cellular (T and natural killer cells) immune response. (Poster) X CONGRESS EUROPEAN SOCIETY FOR ORGAN TRANSPLANTATION, LISBOA, October 6 - 11, 2001. 174. JP Dehoux, B de la Parra, H Bazin, D Latinne, P Gianello. Effect in vitro and in vivo of a rat anti-CD2 monoclonal antibody (LO-CD2b) on pig to baboon xenogeneic cellular (T and Natural Killer cells) immune response. 175. JP Dehoux, B de la Parra, JP Squifflet, H Bazin, D Latinne, P Gianello. Human and nonhuman anti-galactosyl response after injection of rat monoclonal antibody bearing galactosyl epitopes. 45 176. JP Dehoux, B de la Parra, D Latinne, H Bazin, P Gianello. Characterization of baboon antiporcine IgG antibodies after rat anti-μ monoclonal antibody treatment. (Poster) 177. M Otsuka, S Ambiru, K Uryuhara, P Herman, S Talpe, JP Dehoux, P Gianello. Comparison of the early immune response in untreated semi-identical recipients of orthotopic liver and kidney allograft in miniature swine. (Poster) 178. K Uryuhara, F Oike, P Herman, S Talpe, M Otsuka, S Ambiru, JP Dehoux, J Lerut, JB Otte, P Gianello. A 12-day course of FK506 allows long-term tolerance of semi-identical liver allograft in inbred miniature swine. (Poster) EUROCONFERENCES PASTEUR: INSTITUT PASTEUR, PARIS, JUIN 2002 179. Les xénogreffes: où est-on? P.Gianello AMERICAN SOCIETY OF TRANSPLANTATION: Washington, MAY 2003 180. The thymus is required during the induction phase but not the maintenance phase of renal allograft tolerance to miniature swine. P.A.Vagefi, F.Ierino,A.Shimlizu,P.R.Gianello,DH.Sachs, K.Yamada. 9TH CONGRESS OF THE INTERNATIONAL PANCREAS AND ISLET TRANSPLANT ASSOCIATION: Dublin, JULY 11, 2003 181. Porcine pancreatic islets: influence of age on histomorphometry and consequences for In Vivo transplantation. D. Dufrane, R.M. Goebbels, Y. Guiot, J. Rahier, P. Gianello. 17TH FORUM FOR APPLIED BIOTECHNOLOGY: Gent, SEPTEMBER 18-19, 2003 182. Xenotransplantation: how far are we ? P. Gianello ESOT ETCO 2003: Venice, SEPTEMBER 20-24, 2003 183. Thymectomy interferes but does not uniformly abrogate tolerance to semi-identical liver allograft in inbred miniature swine. (Poster) K. Uryuhara, S. Ambiru, J.P. Dehoux, F. Oike, S. Talpe, P. Gianello. 184. Improved survival of orthotopic liver allograft in swine by addition of trophic factors to UW solution. (Poster) S. Ambiru, K. Uryuhara, S. Talpe, J.P. Dehoux, M. van Steenberghe, L. Jacobbi, C. Murphy, J. McAnulty, P. Gianello. 185. Early biological and immune response to semi-identical liver or kidney allograft in miniature swine M. Otsuka, S. Ambiru, K. Uryuhara, P. Herman, S. Talpe, J.P. Dehoux, F. Jamar and P. Gianello. 46 186. Spontaneous baboon cell-mediated cytotoxicity to PAECs : the role of Galactosyl residues. J.P. Dehoux, Y. Nizet, B. de la Parra, C. Lecuivre, H. Bazin, D. Latinne, P. Gianello. 187. Porcine pancreatic islets: influence of age on histomorphometry and consequences for In Vivo transplantation. D. Dufrane, R.M. Goebbels, Y. Guiot, J. Rahier, P. Gianello. VII CONGRESS OF THE IXA: Glasgow, SEPTEMBER 30-OCTOBER 4, 2003 188. Spontaneous baboon cell-mediated cytotoxicity to PAECs : the role of Galactosyl residues. (Poster) J.P. Dehoux, Y. Nizet, B. de la Parra, C. Lecuivre, H. Bazin, D. Latinne, P. Gianello. 189. Porcine pancreatic islets: influence of age on histomorphometry and consequences for In Vivo transplantation. (Poster) D. Dufrane, R.M. Goebbels, Y. Guiot, J. Rahier, P. Gianello. BELGIAN TRANSPLANTATION SOCIETY, ANNUAL MEETING, Brussels, MARCH 11, 2004 190. Diabetes induction in large animal models (pig/monkey) : limitation of streptozotocin (Poster). D. Dufrane, M. van Steenberghe, R.M. Goebbels, Y. Guiot, A. Saliez, P. Gianello. XX INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY, Vienna, SEPTEMBER 5-10, 2004 191. Spontaneous baboon cell-mediated cytotoxicity to paecs : the role of galactosyl residues (Poster). J.P. Dehoux, Y. Nizet, B. de la Parra, C. Lecuivre, H. Bazin, D. Latinne, P. Gianello. 192. A simple method using a polymethylpenten chamber for isolation of human pancreatic islets (Poster). D. Dufrane, R.M. Goebbels, Y. Guiot, J.P. Squifflet, P. Gianello. 193. Does isolation procedure modify the expression of Gal alpha 1,3Gal on porcine pancreatic islets (Poster). R.M. Goebbels, Y. Guiot, P. Gianello, D. Dufrane. 194.Pig islets isolation : control of all parameters in view to obtain a high successful isolation outcome (Poster). P. Gianello, R.M. Goebbels, Y. Guiot, D. Dufrane. 195. In juvenile pigs, diabetes induction by Sreptozotocin is not an appropriate model for islets transplantation but is an interesting “in vivo” model for pancreatic ductal transdifferentiation (Poster). 47 P. Gianello, M. van Steenberghe, R.M. Goebbels, A. Saliez, Y. Guiot, D. Dufrane. 196. Three month immune protection of microencapsulated porcine islets transplanted in primates without immunosuppression : preliminary results (Poster). D. Dufrane, R.M. Goebbels, A. Saliez, M. van Steenberghe, P. Gianello. 197. Ultrastructure of porcine pancreatic islets from young and adult pig prior to and after isolation: potential impact on cellular engraftment (Poster). M. van Steenberghe, R.M. Goebbels, Y. Guiot, P. Gianello, D. Dufrane. 198. Tacrolimus monotherapy TAC-mono in 100 adult liver transplant LT recipients: one year results of a prosepective, randomized, blinded, placebo-controled, single centre study. J. Lerut, J. Mathys, J. Lemaire, V. Van Thuyne, S. Talpe, C. Sempoux, C. Verbaandert, O. Ciccarelli, G. Orlando, R. Roggen, C. De Reyck, J. Rahier, P. Gianello, P. Wallemacq, D. Latinne. 199. Tacrolimus (TAC) and anti-CD2A antibody (BTI-322) in adult liver transplantation (LT) : five years results of a prospective randomized study (Poster). J. Lerut, V. Van Thuyne, J. Mathys, J. Lemaire, R. Gheerardyn, O. Ciccarelli, S. Talpe, J. Rahier, F. Roggen, C. De Reyck, H. Bazin, P. Gianello, J. Hope, D. Latinne. 4EME CONGRES DE LA SOCIETE FRANCOPHONE DE TRANSPLANTATION, Bruxelles, NOVEMBER 18-20, 2004 200. Une méthode simple d’isolement d’îlots de Langerhans humaine à l’aide d’une chambre de polymethylpentène. D. Dufrane, R.M. Goebbels, Y. Guiot, J.P. Squifflet, P. Gianello. 201. Micro-encapsulation d’îlots porcins : isolement d’îlots de Langerhans porcins. D. Dufrane, R.M. Goebbels, Y. Guiot, P. Gianello. 202. Micro-encapsulation d’îlots porcins : limite de la Streptozotocine pour l’induction du diabète dans les gros modèles animaux (porc / primates) : Rôle du GLUT-2 et des cellules bêta précurseurs. D. Dufrane, M. van Steenberghe, R.M. Goebbels, Y. Guiot, A. Saliez, P. Gianello. 203. Micro-encapsulation d’îlots porcins : trois mois de protection immunitaire pour des îlots de Langerhans porcins “micro-encapsulés” et transplantés à des primates non-immunodéprimés : résultats préliminaires. D. Dufrane, M. van Steenberghe, R.M. Goebbels, A. Saliez, P. Gianello. 204. Cytotoxicité cellulaire xénogénéique de lymphocytes de babouin vis-à-vis de cellules endothéliales aortiques porcines : l’importance des résidus galactosyl. J.P. Dehoux, Y. Nizet, B. de la Parra, C. Lecuivre, H. Bazin, D. Latinne, P. Gianello. 10th WORLD CONGRESS OF IPITA (INTERNATIONAL PANCREAS ANS ISLET TRANSPLANT ASSOCIATION), Geneva, MAY 4-7, 2005. 48 205. Six-month immune protection of porcine islets transplanted in primates without any immunosuppression : preliminary results. D. Dufrane, R.M. Goebbels, A. Saliez, Y. Guiot, P. Gianello. 206. Streptozotocin-induced diabetes in large animals (pigs/primates) : role of Glut2 transporter and β-cell plasticity. D. Dufrane, M. van Steenberghe, Y. Guiot, R. Goebbels, A. Saliez, P. Gianello. 207. Parameters significantly influencing the yield of pig islets during isolation (Poster). D. Dufrane, R.M. Goebbels, Y. Guiot, P. Gianello. 208. Rat kidney subcapsular space is a more appropriate site than peritoneum or subcutaneous space to transplant pig encapsulated islets (Poster). D. Dufrane, R.M. Goebbels, A. Saliez, P. Gianello. 8th INTERNATIONAL XENOTRANSPLANTATION CONGRESS (IXA) 2005, Göteborg, SEPTEMBER 10-14, 2005 . 209. Six-month immune protection of porcine islets transplanted in non-diabetic Cynomolgus monkeys without immunosuppression. D. Dufrane, R.M. Goebbels, A. Saliez, Y. Guiot, P. Gianello. 210. Rat kidney subcapsular space is a more appropriate site than peritoneum or subcutaneous space to transplant pig encapsulated islets (Poster). D. Dufrane, R.M. Goebbels, A. Saliez, P. Gianello. 211. Streptozotocin-induced diabetes in large animals (Pigs/Primates): role of GLUT-2 transporter and β-cell plasticity (Poster). D. Dufrane, M. van Steenberghe, Y. Guiot, R.M. Goebbels, A. Saliez, P. Gianello. 12TH CONGRESS OF THE EUROPEAN SOCIETY FOR ORGAN TRANSPLANTATION (ESOT 2005), Geneva, OCTOBER 15-19, 2005 212. Six-month immune protection of porcine islets transplanted in non-diabetic primates without any immunosuppression. D. Dufrane, R.M. Goebbels, A. Saliez, Y. Guiot, P. Gianello. 213. Parameters significantly influencing the yield of pig islets during isolation. D. Dufrane, R.M. Goebbels, Y. Guiot, P. Gianello. 214. Cellular immune unresponsiveness to porcine mesenchymal stem cells (MSC). A. Poncelet, J. Vercruysse, A. Saliez, P. Gianello. 215. Streptozotocin-induced diabetes in large animals (Pigs/Primates): role of GLUT-2 transporter and β-cell plasticity (Poster). D. Dufrane, M. van Steenberghe, Y. Guiot, R.M. Goebbels, A. Saliez, P. Gianello. 5e CONGRES ANNUEL DE LA SOCIETE FRANCOPHONE DE TRANSPLANTATION, 49 Tours, DECEMBER 7-10, 2005 216. Survie et fonction d’îlots de porc encapsulés après transplantation chez le primate nondiabétique et diabétique. D. Dufrane, R.M. Goebbels, A. Saliez, P. Gianello. 25th WORKSHOP OF THE AIDPIT STUDY GROUP, Pisa, FEBRUARY 5-7, 2006 217. Survival and function of encapsulated pig islets after transplantation in non-diabetic and diabetic primates. D. Dufrane, R.M. Goebbels, A. Saliez, P. Gianello. 218. Parameters favoring successful adult pig islets isolations for xenotransplantation in “pig to primate” model. D. Dufrane, W. D’hoore, R.M. Goebbels, A. Saliez, Y. Guiot, P. Gianello. 219. Implantation site significantly influences the biocompatibility and survival of alginate encapsulated pig islets in rats (Poster). D. Dufrane, M. van Steenberghe, R.M. Goebbels, A. Saliez, P. Gianello. THE INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION 26th ANNUAL MEETING AND SCIENTIFIC SESSIONS, Madrid, APRIL 5-8, 2006 220. In vivo immune responses to intracardiac allogeneic porcine mesenchymal stem cell (MSC) transplantation : are tolerogenic regimen required ? A. Poncelet, J. Vercruysse, A. Saliez, P. Gianello. 8TH INTERNATIONAL CONGRESS OF THE CELL TRANSPLANT SOCIETY, Milano, MAY 18-20, 2006 221. Survival and function of encapsulated pig islets after transplantation in non-diabetic and diabetic primates. D. Dufrane, R.M. Goebbels, A. Saliez, P. Gianello. 222. Parameters favoring successful adult pig islets isolations for xenotransplantation in “pig to primate” model (Poster). D. Dufrane, W. D’hoore, R.M. Goebbels, A. Saliez, Y. Guiot, P. Gianello. THE EUROPEAN CHAPTER OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY (TERMIS-EU) MEETING, Rotterdam, OCTOBER 8-11, 2006 223. In vivo biocompatibility of chemically and physically human collagen substitute (Poster). D. Dufrane, M. van Steenberghe, R.M. Goebbels, P. Gianello. 50 BELGIAN TRANSPLANTATION SOCIETY – ANNUAL MEETING, Brussels, MARCH 27, 2007 224. Ph.D. Thesis Session : Université catholique de Louvain – Laboratoire de Chirurgie Expérimentale – Encapsulation of pig islets by alginate matrix to correct streptozotocin-induced diabetes in primates without immunosuppression by Denis Dufrane, M.D.- President of Ph.D. Thesis : P. Gianello. SOCIETY FOR ARTIFICIAL ORGANS ANS SUPPORT SYSTEMS - 1ST ANNUAL TUYOD CONGRESS, Istanbul, JUNE 15-17, 2007 225. Six month control of diabetes by transplantation of encapsulated pig islets in diabetic primates without immunosupppression. D. Dufrane, R.M. Goebbels, P. Gianello. CTS (CELL TRANSPLANT SOCIETY)– IPITA (INTERNATIONAL PANCREAS AND ISLET TRANSPLANT ASSOCIATION) – IXA (INTERNATIONAL XENOTRANSPLANTATION ASSOCIATION) 2007 JOINT CONFERENCE, Minneapolis, SEPTEMBER 15-20, 2007 Xenotransplantation 2007, 14 (5) : 406-407, 441, 467 226. Six month control of diabetes by transplantation of encapsulated pig islets in diabetic primates without immunosupppression. D. Dufrane, R.M. Goebbels, P. Gianello. 227. Encapsulation of pig islets by alginate matrix to correct streptozotocin-induced diabetes in primates without immunosuppression. P. Gianello, D. Dufrane. 228. β-score as a tool for pre-clinical model in islets xenotransplantation (Poster). D. Dufrane, W. D’hoore, R.M. Goebbels, G. Beaurin, P. Gianello. 229. Native pancreatic α-cells adaptation in streptozotocin-induced diabetic primates : importance for islets transplantation (Poster). D. Dufrane, J.F. Maillart, R.M. Goebbels, P. Gianello. ESOT / ETCO 2007 (13TH ESOT Congress & 15TH ETCO Congress), Prague, SEPTEMBER 30 – OCTOBER 3, 2007 230. Six month control of diabetes by transplantation of encapsulated pig islets in diabetic primates without immunosupppression. D. Dufrane, R.M. Goebbels, P. Gianello. 231. β-score as a tool for pre-clinical model in islets xenotransplantation : a primate study (Poster). D. Dufrane, W. D’hoore, R.M. Goebbels, G. P. Gianello. 51 232. Native pancreatic α-cells adaptation in streptozotocin-induced diabetic primates : importance for islets transplantation (Poster). D. Dufrane, J.F. Maillart, R.M. Goebbels, Y. Guiot, P. Gianello. 233. In vivo immune response to allogeneic porcine mesenchymal stem cell (MSC) transplantation : a 12-day course of FK-506 abbrogates humoral response (Poster). A. Poncelet, J. Vercruysse, A. Saliez, P. Gianello. SEANCE ORDINAIRE MENSUELLE DE L’ACADEMIE ROYALE DE MEDECINE DE BELGIQUE 2007, Bruxelles, OCTOBER 20, 2007 234. Correction d’un diabète de type I chez le primate par greffe d’îlots pancréatiques porcins encapsulés. D. Dufrane, P. Gianello AMERICAN HEART ASSOCIATION’S SCIENTIFIC SESSIONS 2007, Orlando, NOVEMBER 4-7, 2007 235. In vivo immune response to allogeneic porcine mesenchymal stem cell (MSC) transplantation : a 12-day course of FK-506 abbrogates humoral response (Poster). A. Poncelet, J. Vercruysse, A. Saliez, P. Gianello ROYAL BELGIAN SOCIETY OF SURGERY, ENDOCRINE SECTION AND KIDNEY/PANCREAS AND ORGAN PROCUREMENT COMMITTE - 25 YEARS OF PANCREAS TRANSPLANTATION IN BELGIUM, Liège, NOVEMBER 15, 2007 236. Encapsulation : Where are we ? D. Dufrane, P. Gianello BELGIAN TRANSPLANTATION SOCIETY – ANNUAL MEETING, Brussels, MARCH 20, 2008 237. Regeneration of muscular defects by a composite graft made of mesenchymal stem cells and human acellular collagen matrix. D. Dufrane, M. van Steenberghe, R.M. Goebbels, C. Lecuivre, C. Galli, P. Gianello 238. Macroencapsulation of human parathyroid tissue for treatment of hypoparathyroidism : an in vivo study. M. Mourad, R.M. Goebbels, N. Bouyer, P. Gianello, D. Dufrane ASSOCIATION DE LANGUE FRANCAISE POUR L’ETUDE DU DIABETE ET DES MALADIES METABOLIQUES (ALFEDIAM) – DIABETOLOGIE, CONGRES FRANCOPHONE ANNUEL, Brussels, MARCH 25-28, 2008 239. Correction du diabète chez le primate par transplantation d’îlots de Langerhans porcins encapsulés sans immunosuppresseurs. D. Dufrane, R.M. Goebbels, G. Beaurin, P. Gianello 52 INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION, 28th ANNUAL MEETING AND SCIENTIFIC SESSIONS, Boston, APRIL 9-12, 2008 240. Intracardiac allogeneic porcine mesenchymal stem cell (MSC) transplantation only elicit neoangiogenesis in viable myocardium. A. Poncelet, A.L. Hiel, D. Hermans, P. Camby, P. Gianello ROCHE SYMPOSIUM – DIABETES : FROM RESEARCH TO MEDICAL PRACTICE -, La Hulpe, APRIL 26, 2008 241. Islets encapsulation for diabetes treatment. D. Dufrane, P. Gianello 11. MINISYMPOSIUM XENOTRANSPLANTATION DER DEUTSCHEN ARBEITSGEMEINSCHAFT XENOTRANSPLANTATION (DAX), Berlin, JUNE 6, 2008. 242. Correction of diabetes in primates by macroencapsulated pig islets. P. Gianello TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY (TERMIS-EU) ANNUAL MEETING, Porto, JUNE 22-26, 2008 243. In vivo immune response to allogeneic porcine Mesenchymal Stem Cell (MSC) transplantation : a 12-day course of FK-506 abbrogates humoral response. A. Poncelet, J. Vercruysse, A. Saliez, P. Gianello 244. Regeneration of muscular defects by a composite graft made of mesenchymal stem cells and human acellular collagen matrix. M. van Steenberghe, R.M. Goebbels, C. Lecuivre, C. Galli, P. Gianello, D. Dufrane 245. Six month control of diabetes by transplantation of encapsulated pig islets in diabetic primates without immunosuppression. D. Dufrane, R.M. Goebbels, G. Beaurin, P. Gianello 246. Does administration of immunosuppressive drugs impact on the immunomodulatory properties of Mesenchymal Stem Cells (MSC): Insights from an in vitro study (Poster). A. Poncelet, Y. Nizet, C. Lecuivre, J. Vercruysse, P. Gianello 247. Macroencapsulation of human parathyroid tissue for treatment of hypoparathyroidism : in vivo study (Poster). D. Dufrane, R.M. Goebbels, N. Bouyer, P. Gianello, M. Mourad 248. Regeneration of abdominal wall musculofascial defect by a human acellular colagen matrix (Poster). D. Dufrane, M. Mourad, M. van Steenberghe, R.M. Goebbels, P. Gianello 53 4th EUROPEAN CONGRESS OF THE INTERNATIONAL FEDERATION FOR MEDICAL AND BIOMEDICAL ENGINEERING, Antwerp, NOVEMBER 23-27, 2008. 249. In vivo biocompatibility selection alginates for bioartificial pancreas transplantation. S. Veriter, J. Mergen, R.M. Goebbels, B. Gallez, P. Gianello, D. Dufrane 250. Six months control of diabetes by transplantation of encapsulated pig islets in diabetic primates without immunosuppression. D. Dufrane, R.M. Goebbels, G. Beaurin, P. Gianello THE TERMIS-NA (TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY-NORTH AMERICA) ANNUAL CONFERENCE & EXPOSITION, San Diego, California, DECEMBER 7-10, 2008 251. Pre-Conference Worshop : Tissue Engineering and Biomaterials Technologies (Sponsored by JDRF and Forecast Technology Group Inc), December 7, 2008 Diabetes correction by pig islet monolayer device in non-human primates. P. Gianello, D. Dufrane 252. Transplantation of composite stem cells and collagen matrix to reconstitute muscular defect (Poster). D. Dufrane, M. van Steenberghe, D. Xhema, R.M. Goebbels, C. Lecuivre, C. Galli, P. Gianello 253. In vivo biocompatibility selection alginates for bioartificial pancreas transplantation (Poster). S. Veriter, J. Mergen, R.M. Goebbels, B. Gallez, P. Gianello, D. Dufrane 254. Diabetes correction by Monolayer pig islets device in Non-Human Primates (Poster). D. Dufrane, R.M. Goebbels, P. Gianello UNIVERSITY OF CALIFORNIA, IRVINE (UCI)/CERCO CO-CONFERENCE, San Diego, California, DECEMBER 11, 2008 255. Clinical research on macroencapsulated islets at University of Louvain. D. Dufrane, P. Gianello BELGIAN TRANSPLANTATION SOCIETY - ANNUAL MEETING 2009, Brussels, MARCH 5, 2009. 256. In vivo selection of alginates for a subcutaneous bioartificial pancreas. S. Veriter, J. Mergen, R.M. Goebbels, N. Aouassar, B. Jordan, P. Levêque, B. Gallez, P. Gianello, D. Dufrane 54 257. The standardization of human pancreatic donors for islet isolations : relation between donor parameters and pancreas structure. D. Dufrane, R.M. Goebbels, N. Aouassar, W. d’Hoore, C. Sempoux, Y. Guiot, D. Van Deynse, M. Mourad, P. Gianello INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION – 29th ANNUAL MEETING AND SCIENTIFIC SESSIONS, Paris, APRIL 22-25, 2009. 258. Immune modulatory properties of mesenchymal stem cells are independent of their derived-tissue of origin and are maintained across xenogeneic barriers (Poster 404). A. Poncelet, Y. Nizet, D. Dufrane, J. Vercruysse, C. Lecuivre, P. Gianello Journal of Heart and lung transplantation 2009, 28(2):S205-S206. 259. Immunosuppressive or immunogenic ? Culture medium strongly influences the in vitro immunomodulatory properties of mesenchymal stem cells (MSC) (Poster). A. Poncelet, P. Gianello, J. Vercruysse, C. Lecuivre, Y. Nizet INTERNATIONAL SYMPOSIUM XENOTRANSPLANTATION – DFGTRANSREGIO RESEARCH GROUP XENOTRANSPLANTATION TOGETHER WITH THE 12th MINISYMPOSIUM XENOTRANSPLANTATION OF THE GERMAN WORKING GROUP XENOTRANSPLANTATION (DAX), Berlin, JUNE 04-05, 2009. 260. Islet cell xenotransplantation : update on recent progress and future perspectives. D. Dufrane, P. Gianello 15th N.A.T. (NANTES/TRANSPLANTATION/ACTUALITES) – BETA CELL REPLACEMENT IN DIABETES, Nantes, JUNE 18th-19th, 2009. 261. L’encapsulation d’îlots xenogéniques. D. Dufrane, P. Gianello 262. In vivo selection of alginates for a subcutaneous bioartificial pancreas (Poster). S. Vériter, J. Mergen, R.M. Goebbels, N. Aouassar, B. Jordan, P. Levêque, B. Gallez, P. Gianello, D. Dufrane 263. The standardization of human pancreatic donors for islet isolations : relation between donor parameters and pancreas structure (Poster). D. Dufrane, R.M. Goebbels, N. Aouassar, W. D’Hoore, C. Sempoux, Y. Guiot, D. Van Deynse, M. Mourad, P. Gianello TTS NEW KEY OPINION LEADER (nKOL) MEETINGS 2009 – Jackson Hole, Wyoming, USA, JULY 16th-19th, 2009. 264. Encapsulated pig islet transplants in non-human primates. D. Dufrane, P. Gianello 55 THE 2009 TRANSPLANTATION RESEARCH INSTITUTE JOINT SYMPOSIUM – Seoul, Corée du Sud, SEPTEMBER 12th, 2009. 265. Pig islets encapsulation : pre-clinical to clinical studies. D. Dufrane, P. Gianello IPITA-IXA 2009 – THE TRANSPLANTATION SOCIETY JOINT MEETING INTERNATIONAL PANCREAS AND ISLET TRANSPLANT ASSOCIATION, INTERNATIONAL XENOTRANSPLANTATION ASSOCIATION, Venice, Italy, OCTOBER 12-16, 2009. 266. The standardization of human pancreatic donors for islet isolation : relation between donor parameters and pancreas structure. D. Dufrane, R.M. Goebbels, N. Aouassar, W. D’Hoore, C. Sempoux, Y. Guiot, D. Van Deynse, M. Mourad, P; Gianello 267. A scoring to evaluate the function of islet grafs in a primate preclinical model. D. Dufrane, R.M. Goebbels, Y. Igarashi, W. D’Hoore, P. Gianello 268. Islet xenotransplantation. P. Gianello, D. Dufrane 269. SLM alginate 3% v/v is optimal for a subcutaneous pig islets monolayer cellular device. S. Veriter; J. Mergen, R.M. Goebbels, N. Aouassar, B. Jordan, P. Levêque, B. Gallez, P. Gianello, D. Dufrane 270. Effect of diabetes on oxygenation and neovascularization for subcutaneous encapsulated islets (Poster). S. Vériter, N. Aouassar, P.Y. Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 271. In vivo incrase of alpha cells in pig islets by low dose of stz improves insulin secretion (Poster). S. Vériter, N. Aouassar, R.M. Goebbels, G. Beaurin, P.Y. Adnet, J. Baert, P. Gianello, D. Dufrane 272. Pig xenogenic adipose-derived mesenchymal stem cells for bone reconstruction (Poster). D. Xhema, M. Schubert, R.M. Goebbels, C.B. Wydemans, B. Lengelé, C. Delloye, C. Galli, P Gianello, D. Dufrane 2009 SEOUL FORUM ON XENOTRANSPLANTATION, XENOTRANSPLANTATION RESEARCH CENTER, Seoul, Corée du Sud, NOVEMBER 21, 2009. 273. Islet cell xenotransplantation : update on recent progress and future perspectives. D. Dufrane, P. Gianello 56 AMERICAN TRANSPLANT CONGRESS 2010, San Diego, USA, MAY 1-5, 2010. 274. Can Mesenchymal Stem Cells improve early neovascularisation of subcutaneous encapsulated islets ? S. Veriter, N. Aouassar, P.Y. Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 275. In Vivo increase of Alpha Cells in pig islets by low dose of Streptozotocin improves insulin secretion (Poster) S. Veriter, N. Aouassar, R.M. Goebbels, G. Beaurin, P.Y. Adnet, P. Gianello, D. Dufrane 276. The standardization of human pancreatic donors for islets isolation : relation between donor parameters and pancreas structure (Poster). D. Dufrane, R.M. Goebbels, N. Aouassar, W. D’Hoore, C. Sempoux; Y. Guiot, D. Van Deynse, M. Mourad, P. Gianello. 277. Effect of diabetes on oxygenation and neovascularization for subcutaneous encapsulated islets (Poster) S. Veriter, N. Aouassar, P.Y. Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 278. β5-score to evaluate islet grafts function in a primate pre-clinical model (Poster). Y. Igarashi, R.M. Goebbels, W. D’Hoore, P. Gianello, D. Dufrane DIGESTIVE DISEASE WEEK, New Orleans, LA, USA, MAY 1-5, 2010. 279. Prospective comparison of full thickness resection of submucosal tumours with and without a new grasping device to help triangulation : the Endolifter (Poster). P.H. Deprez, J. Navez, B. Navez, J.F. Gigot, E. Legrand, P. Gianello, C.P.R. Yeung 18TH MEETING OF THE BENELUX EPR (ELECTRONIC PARAMAGNETIC RESONANCE) SOCIETY, Brussels, JUNE 1ST , 2010. 280. Can Mesenchymal Stem Cells Improve Early Neovascularization of Subcutaneous Encapsulated Islets (Poster) ? S. Veriter, N. Aouassar, M.S. Paridaens, C. Stuckmann, P.Y. Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 16th N.A.T. (Nantes/actualites/transplantation) MEETING – NEW FINDINGS IN XENOTRANSPLANTATION AND VASCULAR CYTOPROTECTION, Nantes, France, JUNE 17th-18th, 2010. 281. Pig islet xenotransplantation. P. Gianello 282. In vivo increase of alpha cells in pig islets by low dose of streptozotocin improves insulin secretion (Poster). S. Veriter, N. Aouassar, G. Beaurin, P.Y. Adnet, P. Gianello, D. Dufrane 57 283. A scoring to evaluate the function of islet grafts in a primate preclinical model (Poster). Y. Igarashi, W. D’hoore, R.M. Goebbels, P. Gianello D. Dufrane XENOME EU NETWORK. INTRODUCTORY COURSE ON TRANSLATIONAL RESEARCH, Glasgow, Scotland, JULY 8th – 9th, 2010. 284. Pig islets for xenotransplantation: islets physiology to in vivo functionality. D. Dufrane, P. Gianello XENOME MONTH 48 MEETING, Lisbon, Portugal, OCTOBER 4th-5th; 2010. 285. Xenome : Engineering of the Porcine Genome for Xenotransplantation. Studies in Primates : a Step Towards Clinical Application. Pig Islets Xenotransplantation. P. Gianello, D. Dufrane 4TH WARSAW TRAINING COURSE OF PRACTICAL TRANSPLANTOLOGY, Warsaw, Poland, OCTOBER 22th –23th; 2010. 286. Pig Islets Xenotransplantation. P. Gianello, D. Dufrane 18TH UNITED EUROPEAN GASTROENTEROLOGY WEEK (UEGW), Barcelona, Spain, OCTOBER 23th – 27th, 2010. 287. Prospective comparison of full thickness resection of submucosal tumours with and without a new grasping device to help triangulation : the endolifter (Poster). P. Deprez, B. Navez, J.F. Gigot, E. Legrand, P. Gianello, R.C. Yeung L’ACADEMIE ROYALE DE MEDECINE DE BELGIQUE ET LA KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIE, SYMPOSIUM Don d’organes et Transplantation : où en sommes-nous en Belgique? Brussels, DECEMBER 9th, 2010. 288. Recherche scientifique en Belgique en transplantation d’organes. A. Lemoine, P. Gianello, D. Monbaliu 1st JOINT AIDPIT AND EPITA WORKSHOP, Innsbruck, Austria, JANUARY 23rd – 25th, 2011. 289. Can mesenchymal stem cells improve early neovascularization of subcutaneous encapsulated islets? S. Veriter, N. Aouassar, MS. Paridaens, PY Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 290. Effect of diabetes and islets on oxygenation and neovascularization for subcutaneous bioartificial pancreas (Poster). S. Veriter, N. Aouassar, PY Adnet, B. Jordan, B Gallez, P. Gianello, D. Dufrane 58 291. The standardization of human pancreatic donors for islets isolation: relation between donor parameters and pancreas structure (Poster). D. Dufrane, R.M. Goebbels, N. Aouassar, W. D’Hoore, C. Sempoux, Y. Guiot, D. Van Deynse, M. Mourad , P. Gianello 8e CONGRES UCL D’ENDOCRINO-DIABETOLOGIE, Woluwé, Belgique, MARCH 5th, 2011. 292. Greffe d’îlots dans le diabète de type 1. D. Dufrane, P. Gianello 24TH ANNUAL MEETING OF THE EUROPEAN MUSCULO-SKELETAL ONCOLOGY SOCIETY (EMSOS), GHENT, BELGIUM, MAY 18TH-20TH, 2011. 293. The safety of human autologous adipose mesenchymal stem cells for bone tissue reconstruction after tumour resection: genetic stability to osteogenic differentiation. D. Dufrane, H. Antoine-Poirel, D. Xhema, N. Aouassar, R.M. Goebbels, W. Andre, G. Ameye, P. Gianello, P.L. Docquier, C. Delloye, D. Dufrane. 13TH WORLD CONGRESS OF INTERNATIONAL PANCREAS AND ISLET TRANSPLANT ASSOCIATION (IPITA), PRAGUE, CZECH REPUBLIC, JUNE 1ST4TH, 2011. 294. Mesenchymal stem cells improve early neovascularization of subcutaneous bioartificial pancreas. S. Veriter, N. Aouassar, M.S. Paridaens, P.Y. Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 295. Oxygenation of subcutaneous bioartificial pancreas : effect of diabetic state and islet encapsulation. S. Veriter, N. Aouassar, P.Y. Adnet, B. Jordan, B. Gallez, P. Gianello, D. Dufrane 296. Gal Kock-out pig islets can modulate the humoral response after the transplantation of macroencapsulated pig islets in diabetic primates. Y. Igarashi, S. Veriter, P. Gianello, D. Dufrane 297. Islets graft preparation in an ISO 9001-certified laboratory for a safety clinical application (Poster). R.M. Goebbels, N. Aouassar, D. Xhema, D. Dufrane 59 VIème CONGRES DE LA SOCIETE FRANCAISE DE BIO INGENIERIE CELLULAIRE ET TISSULAIRE (SFBCT), REIMS, FRANCE, SEPTEMBER 28th, 2011. 298. Amélioration des allogreffes osseuses par cellules souches mésenchymateuses: cellules souches adipeuses vs. cellules souches de moelle osseuse, non-différenciées vs. différenciation ostéogénique (oral + poster). T. Schubert, D. Xhema, S. Veriter, M. Schubert, C. Behets , C. Delloye , P. Gianello, D. Dufrane CTS-IXA 2011 JOINT INTERNATIONAL CONGRESS, MIAMI, USA, OCTOBER 23rd-26th, 2011. 299. Islet xenotransplantation without immunosuppression. P. Gianello 300. Improvement of Bone Allograft by Mesenchymal Stem Cells: undifferentiated vs. Osteogenic Adipose / Bone marrow stem cells. T. Schubert, D. Xhema, S. Veriter, M. Schubert, C. Behets, C. Delloye, P. Gianello, D. Dufrane 301. Pig as a large animal model for bone tissue engineering development. T. Schubert, D. Xhema, G. Beaurin, P.Y. Adnet, P. Gianello, D. Dufrane 302. Islets and mesenchymal stem cells co-encapsulation can improve subcutaneous bioartificial pancreas survival in diabetic primates S. Veriter, N. Aouassar, D. Xhema, G Beaurin, PY Adnet, Y. Igarashi, P. Gianello, D. Dufrane 303. Gal Kock-out pig islets can modulate the humoral response after the transplantation of macroencapsulated pig islets in diabetic primates. Y. Igarashi, S.Veriter, P. Gianello, D. Dufrane 304. In Vivo study of humoral/cellular immune responses to osteoblastic differentiated Adipose Mesenchymal Stem Cell xenografts: Galactosyl-Knock Out vs. Gal positive pigs (Poster). T. Schubert, D. Xhema, H. Poilvache, P. Gianello, D. Dufrane 86ème CONGRES DE LA SOCIETE FRANCAISE DE CHIRURGIE ORTHOPEDIQUE ET TRAUMATOLOGIQUE (SOFCOT), PARIS, FRANCE, NOVEMBER 7th-11th, 2011. 305. Amélioration des allogreffes osseuses par cellules souches mésenchymateuses: cellules souches adipeuses vs. cellules souches de moelle osseuse, non-différenciées vs. différenciation ostéogénique. T. Schubert, D. Xhema, S. Veriter, M. Schubert, C. Behets , C. Delloye , P. Gianello, D. Dufrane 60 306. Modèle animal porcin en ingénierie tissulaire osseuse. T. Schubert, D. Xhema, G. Beaurin, P.Y. Adnet, P. Gianello, D. Dufrane 2nd JOINT AIDPIT AND EPITA WINTER SYMPOSIUM & 31st AIDPIT Worshop, IGLS/INNSBRUCK, AUSTRIA, JANUARY 29th-31st, 2012. 307. New developments in islet xenotransplantation. P. Gianello 308. Co-encapsulation of porcine islets and mesenchymal stem cells can improve subcutaneous bioartificial pancreas in diabetic primates. S. Veriter, N. Aouassar, D. Xhema, G. Beaurin, P.Y. Adnet, Y. Igarashi, P. Gianello, D. Dufrane BELGIAN TRANSPLANTATION SOCIETY - ANNUAL MEETING 2012, BRUSSELS, BELGIUM, MARCH 29th, 2012. 309. In vivo study of humoral/cellular immune responses to osteoblastic differentiated adipose mesenchymal stem cell xenografts : galactosyl-knock out vs. gal positive pigs. T. Schubert, D. Xhema, H. Poilvache, C. Galli, P. Gianello, D. Dufrane 310. Improvement of subcutaneous bioartificial pancreas vascularization and function by coencapsulation of islets and mesenchymal stem cells in diabetic rats/primates. S. Veriter, N. Aouassar, D. Xhema, G. Beaurin, P.Y. Adnet, Y. Igarashi, P. Gianello, D. Dufrane 311. Diabetes control by encapsulated human islets allotransplantation in the subcutaneous tissue : 1 year follow-up for safety and functionality. D. Dufrane, M. Mourad, B. Vandeleene, E. Goffin, P. Gianello, D. Xhema, N. Aouassar, R.M. Goebbels. (Abstract) JOURNEE DE LA SOCIETE FRANCAISE DE RECHERCHE ORTHOPEDIQUE ET TRAUMATOLOGIQUE, PARIS, FRANCE, MARCH 30th, 2012. 312. Mise au point de pertes osseuses irréversibles au niveau fémoral et vertébral dans un modèle pré-clinique porcin. T. Schubert, D. Xhema, S. Lafont, G. Beaurin, C. Delloye, P. Gianello, D. Dufrane AMERICAN TRANSPLANT CONGRESS 2012 – 12TH JOINT ANNUAL MEETING OF THE AMERICAN SOCIETY OF TRANSPLANT SURGEONS AND THE AMERCIAN SOCIETY OF TRANSPLANTATION, BOSTON, USA, JUNE 2nd-6th; 2012. 313. Pancreatic Islet Xenotransplantation. P. Gianello 61 eCM XIII (eCELLS AND MATERIALS) CONGRESS 2012 : BONE FIXATION, REPAIR & REGENERATION, DAVOS, SWITZERLAND, JUNE 24th-26th, 2012. 314. Pig as large animal model for cell therapy in bone tissue engineering. T. Schubert, D. Xhema, S. Lafont, G. Beaurin, P. Gianello, D. Dufrane 20TH ANNIVERSARY ANNUAL MEETING OF EUROPEAN ORTHOPAEDIC RESEARCH SOCIETY (EORS) 2012, AMSTERDAM, THE NETHERLANDS, SEPTEMBER 26th-28th, 2012. 315. Potential of osteoblastic differentiated Adipose Mesenchymal Stem Cells for bone tissue engineering in a porcine pre-clinical model (Oral + Poster). T. Schubert, S. Lafont, G. Beaufin, C. Delloye, P. Gianello, D. Dufrane XXIIEMES JOURNEES LILLY DIABETE (JLD), PARIS, FRANCE, JANUARY 24th25th, 2013. 316. Encapsulation et xéno-greffes. P. Gianello DON D’ORGANES ET TRANSPLANTATION AU QUOTIDIEN - 6EME JOURNEE DE PARTENARIAT – CENTRE DE TRANSPLANTATION D’ORGANES UCL, CHU MONT-GODINNE-DINANT, YVOIR, BELGIUM, FRIDAY 19th, 2013. 317. Perspectives futures en transplantation : apport de la recherche. P. Gianello CONGRES ANNUEL DE LA SOCIETE DE PHARMACO-TOXICOLOGIE CELLULAIRE (SPTC) – CELLULES ET TOXIQUES EN 3D : LA VISION DU FUTUR, CHATENAY-MALABRY, FRANCE, JUNE 6th-7th, 2013. 318. Greffes d’ïlots de Langerhans. P. Gianello