BURHAN GHARAIBEH - University of Pittsburgh

Transcription

BURHAN GHARAIBEH - University of Pittsburgh
BURHAN GHARAIBEH, Ph.D.
Research Assistant Professor
Stem Cell Research Center (SCRC), Department of Orthopaedic Surgery
University of Pittsburgh
Bridgeside Point II Suite 206
450 Technology Drive
Pittsburgh, PA 15219
Tel: 412-648-2716 Fax: 412-648-4066, e-mail: [email protected]
http://www.pitt.edu/~burhan
Education
1997
Texas Tech University, Lubbock, Texas, USA.
Ph.D. in Zoology
Dissertation: “Systematics, distribution, and zoogeography of mammals
of Tunisia”
Advisor: Dr. Robert J. Baker.
1988
Yarmouk University, Irbid, Jordan
M.Sc. in Zoology
Thesis: “Reproduction and growth of three species of Chaetodontidae
(Pisces, Perciformes) in the Gulf of Aqaba”
Advisor: Dr. Neil C. Hulings.
1984
Yarmouk University, Irbid, Jordan
B.Sc. in Biological Sciences
Research Experience
Nov 05- Current
Research Assistant Professor. Stem Cell Research Center,
Department of Orthopaedic Surgery, University of Pittsburgh.
Role: PI, Co-PI, and Co-I on several projects conducted at SCRC.
May 08- Current
Affiliated Faculty at McGowan Institute for Regenerative
Medicine.
Mar 03- Nov 05
Research Specialist. Stem Cell Research Center, Department of
Orthopedic Surgery, University of Pittsburgh.
Apr 01- Mar 03
Post-Doctoral Fellow. Division
Children’s Hospital of Pittsburgh.
June 98- Apr 01
Post-Doctoral Fellow. Department of Human Genetics,
University of Pittsburgh and The Pittsburgh Cytogenetics
Laboratory, Magee-Women’s Hospital of UPMC, Pittsburgh.
Jan 96- Aug 97
Research Assistant. Natural Science Research Lab. The Museum,
Texas Tech University, Lubbock, Texas.
of
Hematology/Oncology,
Teaching Experience
Mar 2002- Current
Research Assistant Professor. Stem Cell Research Center,
Department of Orthopaedic Surgery, University of Pittsburgh.
Teaching Experience: The following block courses: Stem Cells
(Bioengineering- Pathology- MSCMP 3740); Introduction to
Immunobio-therapeutics (Immunology-MSIMM); Research Basis
for Medical Knowledge (Medicine- MSTP). Mentoring duties
include all the graduate students registered in the PhD and M.S.
programs at SCRC, PGY-2 Orthopaedic residents, and
international orthopaedics fellows. I have also mentored over
15 undergraduate students, who rotate in my lab as research
for credit students, volunteers, and summer interns.
Feb 98- June 98
Assistant Professor. Department of Applied Biology, Jordan
University of Science and Technology (JUST), Irbid, Jordan.
Teaching load included the following courses: Animal
Physiology, Seminar, and Introductory Biology. Coordinator for
all general laboratory sessions.
Sep 92- Dec 95
Teaching Assistant. Department of Biological Sciences, Texas
Tech University. Teaching load included the lab periods of
Vertebrate Structure and Development, Comparative Animal
Physiology, and Human Anatomy and Physiology
Sep 90- Dec 91
Teaching Assistant. Department of Applied Biological Sciences,
Jordan University of Science and Technology, Irbid, Jordan.
Teaching load included the lab periods of the following
courses: Invertebrate Zoology, and General Biology.
Sep 88- Sep 90
Jordan Armed Forces. Draftee (compulsory army service).
Royal Wireless Communications Corps. Jordan. Teaching load
included courses in English language for wireless
communications cadets.
Feb 88- Aug 88
Part-time lecturer. Department of Biological Sciences,
Yarmouk University, Jordan. Teaching load included the lab
periods of Marine Biology, and Ecology.
Sep 84- Jan 84
Teaching and Research Assistant. Department of Biological
Sciences, Yarmouk University. Teaching load included the lab
periods of Comparative Chordate Anatomy, and Ecology.
Honors and Awards
2008
Honorary Research Associate, Natural Science Research Laboratory,
Museum of Texas Tech University, Lubbock, Texas.
2006
NIH NIAMS Spotlight on Research - May 2006. Deasy B, Gharaibeh BM,
Pollett JB, Jones MM, Lucas MA, Kanda Y, Huard J: Long-term selfGharaibeh-2
renewal of postnatal muscle-derived stem cells. Incytes- American
Society of Cell Biology Newsletter: Vol. 16, No. 7, July 2005.
2005
AACR-ASTRAZENECA Scholar in Training Award - April 2005. Pollett J,
Olshanski A, Gharaibeh B, Corsi K, Usas A, Peng H, Huard J:
Pleuripotency, a double-edged sword: mixed differentiation signals
induce tumor formation in vivo. American Association for Cancer
Research 96th Annual Meeting, Anaheim, CA: April 16-20, 2005.
2005
Young Investigator’s Award - June 2005. Payne TR, Oshima H, Okada M,
Gharaibeh B, Momoi N, Tobita K, Keller BB, Peng H, Huard J: Functional
repair of infarcted hearts mediated by skeletal muscle stem cells and
their secretion of VEGF. 2005 FASEB Summer Research Conference:
Skeletal Muscle Satellite and Stem Cells, Tucson, AZ: July 11-16, 2005.
Invention Disclosures
2008
Lavasani M, Gehrmann S, Gharaibeh B, Clark K, Pollett J, Kaufmann R,
Huard J. Role of venous nerve guides in peripheral nerve regeneration.
University of Pittsburgh reference number 01660. March 2008.
Research Grants
Jan 09- Jun 010
Cook MyoSite, Inc. Sponsored project. No cost extension.
Jan 07- Jun 09
Cook MyoSite, Inc. Sponsored project for years 5-6". PI. 30%
(3.6 Calendar months). $250,000 direct costs.
May 09- Mar 011
1R21-HL094402-01 (Tobita, PI) (Gharaibeh, Co-I). Threedimensional cardiac gel bioreactor for functioning
cardiomyocyte induction from human skeletal muscle
derived stem cells.
Jan 03– Dec 04
Research Advisory Committee. Children’s Hospital of
Pittsburgh. “Aberrant DNA Synthesis Mediated by the c-Myc
Oncogenes.” Fellowship Funding. $ 85,000.
1998
Deanship of Scientific Research, Jordan University of
Science and Technology (Principal Investigator). “Natural
History Museum at the Jordan University of Science and
Technology.” Equivalent of $ 18,500.
1996
Section of Mammals, Carnegie Museum of Natural History
(Predoctoral grant). “Study of the systematics, distribution,
and zoogeography of mammals of Tunisia.” $4,000
Journal Publications
2009
1. Huard J, Gharaibeh B, and Usas A. Regenerative medicine based on muscle
derived stem cells. Operative Techniques in Orthopaedics. Accepted.
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2. Alejandro Nieponice, Lorenzo Soletti, Jianjun Guan, Yi Hong, Burhan
Gharaibeh, Timothy M Maul, Johnny Huard, William R. Wagner, and David
A. Vorp. In-vivo Assessment of a Tissue-engineered Vascular Graft
Combining a Biodegradable Elastomeric Scaffold and Muscle-Derived Stem
Cells in a Rat Model. Submitted to Circulation Research.
3. Tomoyuki Matsumoto, Gregory M. Cooper, Burhan Gharaibeh, Laura B.
Meszaros, Guangheng Li, Arvydas Usas, Freddie H. Fu, and Johnny Huard.
Cartilage Repair in a Rat Model of Osteoarthritis through Intraarticular
Transplantation of Muscle-Derived Stem Cells Expressing Bone
Morphogenetic Protein 4 and Soluble Flt-1. Arthritis and Rheumatism. Vol.
60, No (5):1390-405.
4. Matsumoto T, Cooper GM, Gharaibeh B, Meszaros LB, Li G, Usas A, Fu FH,
Huard J. Blocking VEGF as a potential approach to improve cartilage
healing after osteoarthritis. J Musculoskelet Neuronal Interact. 2008 OctDec;8(4):316-7.
5. Mitra Lavasani, Jonathan B Pollett; Arvydas Usas; Sebastian Gehrmann; Aiping
Lu; Burhan Gharaibeh; Kathrine A Clark; Bin Sun; Robert A Kaufmann;
Bruno Péault; Robert J Goitz; and Johnny Huard. Muscle and Blood VesselDerived Progenitor Cells Actively Participate in the Functional
Regeneration of Peripheral Nerve. Presubmission edits.
6. Clause, K, JP Tinney, LJ Liu, B Gharaibeh, KL Fujimoto, WR Wagner, JC Ralphe,
BB Keller, J Huard, and K Tobita. 2009. Cardiomyocyte induction from
skeletal muscle derived stem cells using cell aggregates and a threedimensional gel bioreactor. Tissue Eng Part C Methods. 2009 Jul 14.
2008
7. Gharaibeh, B, Lu, A, J Tebbets, Zheng, B, Feduska, A, Crisan, M, Peault, B,
Cummins, J and Huard. 2008. Isolation of murine muscle-derived stem
cells by differential adherence characteristics (The Preplate Technique).
Nature Protocols. 3(9):1501-9.
8. Matsumoto T, Cooper GM, Gharaibeh B, Meszaros LB, Li G, Usas A, Fu FH,
Huard J. Blocking VEGF as a potential approach to improve cartilage
healing after osteoarthritis. J Musculoskelet Neuronal Interact. 2008 OctDec;8(4):316-7.
9. Matsumoto, T., Cooper, G. M., Gharaibeh, B., Meszaros, L. B., Li, G., Usas, A.,
Fu, F. H., and Huard, J. Blocking VEGF as a potential approach to improve
cartilage healing after OA. Accepted in Arthritis and Rheumatism.
10. Matsumoto, T., Cooper, G.M., Gharaibeh, B., Meszaros, L.B., Li, G., Usas, A.,
Fu, F.H., and Huard, J. 2008. Cartilage repair after osteoarthritis through
intra-articular transplantation of muscle stem cells expressing BMP4 and
sFlt1. Arthritis and Rheumatism. In Press.
11. Clause K, Tinney JP, Liu LJ, Gharaibeh B, Fujimoto KL, Wagner WR, Ralphe JC,
Keller BB, Huard J, Tobita K. 2007. Functioning engineered cardiac tissue
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from skeletal muscle-derived stem cells. CIRCULATION RESEARCH, Volume:
101(5): E56-E56.
2007
12. Zheng, B, B Cao, M Crisan, B Sun, G Li, A Logar, S Yap, JB Pollett, L Drowley, T
Cassino, B Gharaibeh, BM Deasy, J Huard, and B Peault. 2007. Prospective
identification of myogenic endothelial cells in human skeletal muscle.
Nature Biotechnology. 25:1025-34.
13. Pollett, JB, KA Corsi, KR Weiss, GM Cooper, DA Barry, B Gharaibeh, and J
Huard. 2007. Malignant transformation of multipotent muscle-derived cells
by concurrent differentiation signals. Stem Cells. 25:2302-11.
14. Deasy, BM, A Lu, JC Tebbets, JM Feduska, RC Schugar, JB Pollett, B Sun, KL
Urish, BM Gharaibeh, B Cao, RT Rubin, and J Huard. 2007. A role for cell
sex in stem cell-mediated skeletal muscle regeneration: female cells have
higher muscle regeneration efficiency. J Cell Biol. 177:73-86.
15. Clause, K, JP Tinney, LJ Liu, B Gharaibeh, KL Fujimoto, WR Wagner, JC Ralphe,
BB Keller, J Huard, and K Tobita. 2007. Functioning engineered cardiac
tissue from skeletal muscle-derived stem cells. Circulation Research.
101:E56-E56.
2005
16. Deasy BM, Gharaibeh BM, Pollett JB, Jones MM, Lucas MA, Kanda Y, Huard J.
2005. Long-Term Self-Renewal of Postnatal Muscle-derived Stem Cells. Mol
Biol Cell. Jul;16(7): 3323-33.
17. Oshima H, Payne TR, Urish KL, Sakai T, Ling Y, Gharaibeh B, Tobita K, Keller
BB, Cummins JH, Huard J. 2005. Differential myocardial infarct repair
with muscle stem cells compared to myoblasts. Molecular Therapy. 12(6):
1130-1141.
18. Payne TR, Oshima H, Sakai T, Ling Y, Gharaibeh B, Cummins J, Huard J. 2005.
Regeneration of dystrophin-expressing myocytes in the mdx heart by
skeletal muscle stem cells. Gene Ther. Aug;12(16): 1264-74.
2000
19. Saunders, WS, M Shuster, X Huang, BM Gharaibeh, AH Enyenihi, I Petersen, and
SM Gollin. 2000. Chromosomal Instability and Cytoskeletal Defects in Oral
Cancer Cells. Proceeding of the National Academy of Sciences, 97(1): 303308.
20. Rifai, L, WN Al-Melhim, BM Gharaibeh and ZS Amr. 2000. The diet of the desert
Eagle Owl, Bubo bubo ascalaphus, in the Eastern desert of Jordan. Journal
of Arid Environments. 44: 369-372.
21. Gharaibeh, BM and DA Schlitter. 1997. Mammals of the Holy Land (book
review). Journal of Mammalogy, 78(4): 1290-1291.
22. Gharaibeh, BM and C Jones. 1996. Myosciurus pumilio, the West African pygmy
squirrel. Mammalian Species, 523: 1-3.
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23. Gharaibeh, BM and M Qumsiyeh. 1995. Otonycteris hemprichii, Hemprich's
long-eared bat. Mammalian Species, 517: 1-4.
24. Goetze, JR, FD Yancey, II, C Jones, and BM Gharaibeh. 1995. Noteworthy
records of mammals from the Edwards Plateau of central Texas. Texas
Journal of Science, 47(1): 3-8.
25. Yancey, FD, II, JR Goetze, BM Gharaibeh, and C Jones. 1995. Distributional
records of small mammals from the Southwestern Rolling Plains of Texas.
Texas Journal of Science, 47(2): 101-105.
26. Gharaibeh, BM and NC Hulings. 1990. Reproduction of Chaetodon austriacus, C.
fasciatus and C. paucifasciatus (Chaetodontidae, Perciformes) in the
Jordan Gulf of Aqaba. Environmental Biology of Fishes, 29: 67-72.
Book Chapters
1. Gharaibeh B, L Drowley, and J Huard. 2009. Muscle derived stem cells: a
model for stem cell therapy in regenerative medicine. In Stem Cells and
Regenerative Medicine: From Embryology to Tissue engineering. Humana
Press. (K. Appasani and R.K. Appasani, Eds.). Accepted.
2. Gharaibeh, BM and C Jones. 1999. Mephitis macroura. Pp. 186-188, in The
Smithsonian Book of North American Mammals. Smithsonian Institution
Press. (D. Wilson and S. Ruff, Eds.). 750 pp.
3. Hugh H Genoways (Editor) Robert J Baker (Editor) Burhan M Gharaibeh
(Illustrator) Terry A. Vaughan (Illustrator). 1996. Contributions in
Mammalogy : A Memorial Volume Honoring Dr. J Knox Jones, JR. Museum
of Texas Tech University. 315 pp.
Proceedings
1. Baker, RJ, B Albin, RD Bradley, JJ Bull, J Burns, KA Clark, G Edson, RE Estrada,
E Farley, CB Fedler, BM Gharaibeh, RL Hammer, C Jones, R Monk, JT
Montford, G Moore, NC Parker, J Raulings, A Sansom, DJ Schmidly, RW
Sims, H Wichman, and FD Yancey. 1996. Natural Science database:
Resource Management and Public Health. Proceedings of the 4th Annual
Conference of the Organization of Fish and Wildlife Information Managers.
July 1996: 10-20.
Recent Abstracts and Posters
2009
1. 1. Wei He, Alejandro Nieponice, Lorenzo Soletti, Burhan Gharaibeh, Yi Hong,
Mihaela Crisan, Bruno Peault, William R. Wagner, David A. Vorp. TissueEngineered Vascular Grafts from Human Pericytes. NHLBI Symposium on
Cardiovascular Regenerative Medicine. Submitted.
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2. Xiang G; Wang B; Gharaibeh B; Huard J. Cardiogenic Differentiation of Skeletal
Muscle-derived Stem Cells induced by Wnt11 Gene Transfer. NHLBI Symposium
on Cardiovascular Regenerative Medicine. Submitted.
3. Aki Osawa, Tomoyuki Matsumoto, Seiji Kubo, Burhan Gharaibeh, Alison Logar,
Arvydas Usas, Hisashi Kurosawa, Christopher Harner, Johnny Huard.
Characterization of Human Meniscus-Derived Vascular Stem Cells; Comparison
of Periphery and Inner cells. 55th Annual Meeting of ORS. Poster No. 1375 Las
Vegas. Feb 22-25. 2009
4. Aiping Lu, Mitra Lavasani, Joseph Feduska, Jinhong Zhu, Burhan Gharaibeh, Laura
Niedernhofer, Johnny Huard. Defective Proliferation and Myogenic
Differentiation of Muscle-Derived Stem Cells Isolated from a Murine Model of
Accelerated Aging. Paper No. 353. ORS. Las Vegas. Feb 22-25. 2009.
5. Tomoyuki Matsumoto, Gregory Cooper, Burhan Gharaibeh, Laura Meszaros,
Guangheng Li, Arvydas Usas, Freddie Fu, Johnny Huard. Cartilage Repair after
Osteoarthritis through Intra-articular Injection of Muscle Stem Cells Expressing
BMP4 and sFlt1. Poster No. 1367. ORS. Las Vegas. Feb 22-25. 2009
2008
6. Tomoyuki Matsumoto, Gregory M. Cooper, Burhan Gharaibeh, Laura B. Meszaros,
Guangheng Li, Arvydas, Usas, Freddie H. Fu, Johnny Huard. Blocking VEGF as a
Potential Approach To Improve Cartilage Healing after OA. ASGT 11th Annual
Meeting. Boston, Massachusetts May 28–June 1, 2008, USA. Oral Abstract # 74.
Oral Abstract Sessions
7. Gharaibeh B, Tebbets J, Lu A, Lavasani M, Tobita K, Phillippi J, Wagner W, Huard
J. Isolation of Muscle Derived Cells from Various Mammalian Species by the
Preplate Technique. The Orthopaedic Research Society (ORS) 54th Annual
Meeting; March 2-5, 2008; San Francisco, CA.
8. Lavasani M, Gehrmann S, Gharaibeh B, Clark K, Pollett J, Kaufmann R, Goitz R,
Huard J. Role of Venous Nerve Guides in Peripheral Nerve Regeneration. The
Orthopaedic Research. Society (ORS) 54th Annual Meeting; March 2-5, 2008;
San Francisco, CA.
9. Matasumoto T, Cooper G, Gharaibeh B, Meszaros L, Li G, Usas A, Fu F, Huard J.
Blocking VEGF as a potential approach to improve cartilage healing after OA.
American Society of Gene Therapy (ASGT) 11th Annual Meeting; May 28 – June 1,
2008; Boston, MA.
10. Zhu, J, Li, Y, Gharaibeh, B, Huard, J. The use of follistatin to improve the
transplantation of muscle-derived stem cells. New Directions in Biology &
Disease of Skeletal Muscle. April 27- April 30, 2008. New Orleans, LA.
11. Gupta, N, Soletti, L, Nieponice, A, Gharaibeh, B, Konig, G, Guan, J, Hong, Y,
Huard, J, Wagner, W R, and Vorp, D. Preclinical Evaluation of an Autologous
Stem Cell-Based Tissue-Engineered Vascular Graft in a Pig Model. Vascular
Annual Meeting. June 4-8, 2008. San Diego, CA.
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12. Lorenzo Soletti, Alejandro Nieponice, Burhan Gharaibeh, Nav Y Gupta, Jianjun
Guan, Yi Hong, Johnny Huard, William R Wagner, and David A Vorp.
Development of a Tissue-Engineered Vascular Graft in Rat and Pig Models.
ISACB. 2008. Bordeaux, France.
13. Alejandro Nieponice, NavYash Gupta, Lorenzo Soletti, Burhan Gharaibeh, Bridget
M. Deasy, Jianjun Guan, Johnny Huard, William R. Wagner and David A. Vorp.
Development of a tissue engineered vascular graft fabricated with musclederived stem cells and a biodegradable elastomeric scaffold in an in-vivo model.
Eastern Vascular Society. Sept. 2008. Boston, MA.
14. Kelly C. Clause, Joseph P. Tinney, Li J. Liu, Burhan Gharaibeh, Johnny Huard,
Jonathan A. Kirk, Sanjeev G. Shroff, Kazuro L. Fujimoto, William R. Wagner,
John C. Ralphe, Bradley B. Keller, Kimimasa Tobita. Cardiomyocyte induction
from skeletal muscle derived stem cells using cell aggregates and a threedimensional cardiac gel bioreactor. ISSCR 2008. Philadelphia, PA.
2007
15. Kelly Clause, Joseph P Tinney, Li J Liu, Burhan Gharaibeh, Kazuro L Fujimoto,
William R Wagner, John C Ralphe, Bradley B Keller, Johnny Huard, Kimimasa
Tobita. Functioning Engineered Cardiac Tissue from Skeletal Muscle–Derived
Stem Cells. 4th Annual Symposium of the American Heart Association Council
on Basic Cardiovascular Sciences. July 30–August 2, 2007. Keystone Conference
Center, Keystone, CO.
16. Clause KM, Tinney JP, Gharaibeh B, Fujimoto KL, Wagner WR, Keller BB, Huard J,
Kimimasa T. Functioning engineered cardiac tissue from skeletal musclederived stem cells. McGowan Institute for Regenerative Medicine Retreat; 2007
Mar 5-6; Nemacolin Woodlands Resort, Farmington, PA.
2006
17. Zheng B, Cao B, Sun B, Li GH, Gharaibeh B, Crisan M, Logar A, Peault B, Huard J.
Myogenic-endothelial cells, vessel-associated myogenic progenitors from human
skeletal muscle, possess high myogenic potential. The Orthopaedic Research
Society 52nd Annual Meeting; 2006 Mar 19-22; Chicago, IL.
2005
18. Deasy, BM, Aiping Lu , Karin Corsi, Jonathan Pollett , Anne Olshanski, Ken Urish,
Jessica C. Tebbets, Burhan M. Gharaibeh, and Johnny Huard. Sex differences
in muscle stem cells. FASEB Conference, Muscle satellite and stem cells, 4th
International Meeting. June 2005. Tuscon, AZ.
19. Deasy BM, Lu A, Tebbets JC, Urish KM, Gharaibeh BM, Payne TR, Kekre N, Jones
MM, Rubin RT, and Huard J. Sex-related Differences Between Male And Female
Muscle-derived Stem Cells. 51st Annual Orthopedic Research Society Meeting.
2005. Washington, D.C.
20. Nieponice, A., Deasy, B.M., Gharaibeh, B., Soletti, L., Guan, J., Huard, J.,
Wagner, W.R., Vorp, D.A. Characterization of Muscle Derived Stem Cells within
a Novel Tissue Engineered Vascular Graft. Tissue Engineering Society
International, December 2005, Shanghai, China.
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21. Nieponice A, Gharaibeh B, Soletti L, Deasy BM, Guan J, Huard J, Wagner WR, and
Vorp DA. Assessment of a tissue engineered vascular graft fabricated with
muscle-derived stem cells and a biodegradable elastomeric scaffold. ISCAB
22. Oshima H, Payne TR, Urish KL, Sakai T, Ling Y, Gharaibeh B, Tobita K, Keller BB,
Cummins JH, Huard J. June 2005. Muscle stem cells provide superior infarct
repair when compared with myoblasts. American Society of Gene Therapy’s 8th
Annual Meeting. St. Louis, MO.
23. Oshima H, Payne TR, Urish KL, Sakai T, Ling Y, Gharaibeh B, Tobita K, Keller BB,
Cummins JH, Huard J. June 2005. Improved myocardial infarct repair with
muscle stem cells compared with myoblasts. Regenerate Conference. Atlanta,
GA.
24. Payne TR, Oshima H, Okada M, Gharaibeh B, Momoi N, Tobita K, Keller BB, Peng H,
Huard J. June 2005. Functional repair of infarcted hearts mediated by skeletal
muscle stem cells and their secretion of VEGF. FASEB Conference on Skeletal
Muscle and Stem Cells. Tucson, AZ.
25. Payne TR, Oshima H, Okada M, Gharaibeh B, Urish K, Tobita K, Momoi N, Keller BB,
Peng H, Huard J. June 2005. Skeletal muscle stem cells for cardiac repair;
survival, differentiation, angiogenesis, and VEGF expression. International
Society for Stem Cell Research 3rd Annual Meeting, San Francisco, CA.
26. Pollet JB, Olshanski A, Gharaibeh B, Corsi K, Usas A, Peng H, and Huard J.
Pleuripotency, a double edged sword: mixed differentiation signals induce
tumor formation in vivo. American Association for Cancer Research, 96th
Annual Meeting, April 16-20, 2005, Anaheim, CA.
27. Pollett JB, Olshanski A, Gharaibeh B, Corsi K, Usas A, Peng H, Huard J. Coexpression of BMP4 and Noggin in vivo induces tumor formation in a dosedependent manner. The Orthopaedic Research Society 51st Annual Meeting;
2005 Feb 20-23; Washington, DC.
28. Urish K, Deasy BM, Payne TR, Oshima H, Kekre N, Tebbets J, Gharaibeh B, Lu A,
Piganelli J, Huard J. Resistance to stress is an indicator of the regenerative
capacity of skeletal stem cells. 3rd Annual Meeting of the International Society
for Stem Cell Research. June 2005, San Francisco, CA.
2004
29. Deasy, B.M, Gharaibeh, B.M., Jones M.M., Lucas, M.A., Huard J. (2004) LongTerm Proliferation Potential Of Muscle-Derived Stem Cells: Muscle-derived
Stem Cells Have Highly Extended, But Not Unlimited, Expansion Capability.
International Society for Stem Cell Research June, 2004. Boston, MA.
30. Deasy, B.M., Gharaibeh, B.M., M. Jones, A. Lu, J. Tebbets, J. Huard. (2004).
Gender Differences in Transplantation Efficiency using Muscle-derived Stem
Cells for Muscular Dystrophy. American Society for Gene Therapy. June 2004.
Minneapolis, MN.
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31. Deasy, B.M, Gharaibeh, B.M., Jones M.M., Lucas, M.A., Huard J. (2004) Musclederived Stem cells display and extended but not unlimited, expansion
capability: Implication for Muscle Regeneration. American Society for Gene
Therapy. June 2004. Minneapolis, MN.
32. Payne TR, Oshima H, Sakai T, Ling Y, Gharaibeh B, Cummins JH, Huard J. May
2004. “Muscle stem cells deliver dystrophin and adopt a cardiac phenotype
through both differentiation and fusion in the dystrophic (mdx) heart. American
Society of Gene Therapy Conference, Minneapolis, MN. Molecular Therapy.
Volume 9. Supplement 1.
33. Deasy, B.M, Gharaibeh, BM, Jones, M, Lucas, M, Huard, J. 2004. Long-term
proliferation potential of Muscle-derived stem cells. The 2cd Annual Meeting of
the International Society of Stem Cell Research, Jun 10-13, Boston, MA.
34. Deasy, B.M, Gharaibeh, BM, Jones, M, Lu, A, Tebbets, J, Huard, J. 2004. Gender
differences in transplantation efficiency using muscle-derived stem cells for
muscular dystrophy. The 7th annual Meeting of the American Society of Gene
Therapy, Minneapolis, MN.
35. Deasy, B.M, Gharaibeh, BM, Jones, M, Lucas, M, Huard, J. 2004. Muscle-derived
stem cells display an extended but not unlimited, expansion capability:
implication for muscle regeneration. The 7th annual Meeting of the American
Society of Gene Therapy, Minneapolis, MN.
2000
36. Kochmar S, Bay C, Gharaibeh B, Surti U. June 22-25, 2000. 47,XX, +inv
dup(15)(q12) in a patient with severe mental retardation and dysmorphic
features. Poster Presentation. The Association of Genetic Technologists 25th
Anniversary Meeting, Scottsdale, Arizona. Abstract # 31.
37. McPherson EW, Clemens MM, Kochmar S, Gharaibeh B, Surti U. October 3-7, 2000.
Supernumerary ring chromosome 11 mosaicism causing retinal colobomas.
Poster Presentation. The American Society of Human Genetics 50th Annual
Meeting, Philadelphia. Abstract # 846.
38. Huang X, Shuster M, Godfrey TE, Saunders WS, Gharaibeh BM, Gollin SM. October
3-7, 2000. Gene amplification occurs via breakage-fusion-bridge cycles in oral
cancer cells. Poster Presentation. The American Society of Human Genetics 50th
Annual Meeting, Philadelphia. Abstract # 314.
1999
39. Gharaibeh, B. M., X. Huang, W. S. Saunders, I. Petersen, S. M. Gollin. October
19-23, 1999. Endoreduplication in oral squamous cell carcinoma (OSCC). Poster
Presentation. The American Society of Human Genetics 49th Annual Meeting,
San Francisco. Abstract # 890.
40. Huang, X., W.S. Saunders, B. M. Gharaibeh, M. Shuster, A. H. Enyehini, and S. M.
Gollin. October 19-23, 1999. Aneuploidy, chromosomal instability, and
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cytoskeletal defects in oral squamous cell carcinoma (OSCC) cells. The
American Society of Human Genetics 49th Annual Meeting, San Francisco.
Abstract # 902.
1998
41. Gharaibeh, B. M. May 18, 1998. G-banding data for Meriones shawi (Duvernoy,
1842) and a reevaluation of the phylogeny of the jirds (Rodentia, Gerbillidae).
The First Annual Scientific Day of the Faculty of Science & Arts, Jordan
University of Science and Technology, Irbid, Jordan.
1995
42. Gharaibeh, B. M. March 31, 1995. Geographic variation in the elephant shrew
Elephantulus rozeti (Mammalia, Macrosclididae) from Tunisia. 9th Annual
Graduate Research Forum, Department of Biological Sciences, Texas Tech
University, Lubbock, Texas.
Article and Grant Editor and Reviewer
1.
2.
3.
4.
Article Review. Journal of Mammalogy
Book Review. Texas Tech Press.
Grant Review. Arizona Science Foundation.
Grant Review. Leeds University. England.
Invited Speaker
February 8-9, 2009
October 21, 2007
June 11, 2007
Growth Factors in Sports Medicine Symposium. ASPETAR,
Qatar Orthopaedic and Sports Medicine Hospital. Doha,
Qatar.
International Biotechnology-Engineering Meeting. School of
Engineering, Tecnológico de Monterrey (ITESM), Campus
Cuernavaca, Mexico.
Continuing Medical Education (CME) Program, Department
of Pediatrics, Hamad Medical Corporation, Doha, Qatar..
Public Relations
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Interview with Aljazeera Network TV Network. November 29th, 2008
Pittsburgh Tribune-Review. December 2, 2008. Stem-cell rules address safety,
ethics. http://www.pittsburghlive.com/x/pittsburghtrib/search/s_601408.html
University of Pittsburgh Service Committees
2009- Current
Faculty Senate, University of Pittsburgh. Commonwealth
Relations and Community Relations Committees
2007- Current
Institutional Review Board (IRB), the
Pittsburgh and UPMC. Standing Member
2004- Current
Animal Research and Care Committee (ARCC), Children’s
Hospital of Pittsburgh Member.
University
Professional Societies Memberships
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of
2008- Current
2004- Current
2004- Current
1999- Current
1999- 2005
1993- 2000
1993- 1998
1993- 1998
1993- 1998
1988-1992
1996-1998
1996-1998
American Society for Gene Therapy
Orthopedic Research Society
International Stem Cell Research Society
American Society of Human Genetics
Pittsburgh Cytogenetics Club
American Society of Mammalogists
Texas Society of Mammalogists
Texas Academy of Sciences
Southwestern Association of Naturalists
Royal Society for the Conservation of Nature, Jordan
Tunisian Life Sciences Society, Tunisia
Tunisian Scientific Consortium, Tunisia
Community Outreach
Design consultant. Science Advisory Committee, Pittsburgh Tissue Engineering
Initiative, McGowan Institute for Regenerative Medicine and Carnegie Science
Center. “If A Star Fish Can Grow An Arm, Why Can’t I ?” Opening April 2009.
Popular science presentations. Stem cells, bioethics, and regenerative medicine.
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Pittsburgh Public School Gifted Program, Pittsburgh.
Pittsburgh Tissue Engineering Initiative Teacher-Workshop, Central Catholic High School,
Pittsburgh.
Advanced Placement Class, Central Catholic High School, Oakland, Pittsburgh.
Temple Mount Sinai Adult Education Program, Squirrel Hill, Pittsburgh.
Languages (Other than English)
Spanish- intermediate level.
French- basic knowledge.
Arabic- native fluency.
Reference are furnished upon request
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