Répertoire

D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
THROMBOSIS
Area: Cardiovascular and metabolic diseases
TARGETED PATHOLOGY/PATHOLOGIES
>V
enous thromboembolic disease
>L
ower limb obstructive arteriopathy (chronic lower limb
critical ischemia)
METHODOLOGY RESOURCES
>M
edical networks dedicated to thrombosis: Thrombose
Picardie-Côte d’Opale network RTVN network, HTAVASC
network, Normandy networks
> Associations for vascular medicine medical continuing
education (ARMV)
> Inter-regional vascular medicine network
>N
ational thrombosis network
INDUSTRY PARTNERS
Bayer,
Boehringer,
GlaxoSmithKline,
Léo,
Sanofi-Aventis,
Daiichi Sankyo…
ACTIVE PATIENT POPULATION
Patients monitored for rare thrombophilias in the 4
University Hospitals and the associated hospitals: cohort
of 1,100 patients.
PARTNER DEPARTMENTS
Cardiology, surgery and vascular medicine departments,
haemostasis, internal medicine, radiology and any other
department concerned by this pathology.
TEAMS
Project co-ordinator:
Dr Marie-Antoinette SEVESTRE
Unité de médecine vasculaire
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.45.59.30
Fax:+33 3.22.45.53.38
M [email protected]
Local contact people:
AMIENS
Dr MA SEVESTRE
m [email protected]
CAEN
Dr A. LEQUERREC - m [email protected]
Laboratoire d’hépatologie - Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
S +33 2.31.06.50.58 - Fax: +33 2.31.06.50.15
Dr C. LE HELLO - m [email protected]
Service de Médecine vasculaire - Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
S +33 2.31.06.49.05 - Fax: +33 2.31.94.53.45
LILLE
Pr B. JUDE - m [email protected]
Laboratoire d’hématologie - Hôpital cardiologique
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.48.91 - Fax: +33 3.20.44.69.89
Dr N. TRILLOT - m [email protected]
Service d’Hématologie - Hôpital Cardiologique
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.59.39 - Fax: +33 3.20.44.68.50
ROUEN
Pr H. LEVESQUE - m [email protected]
Service de médecine interne
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.90.03 - Fax: +33 2.32.88.90.26
Dr JY Borg - m [email protected]
Service Hématologie - Bâtiment IBC
CHU Rouen ,1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.02.49
ARC co-ordinator:
Mohamed AIT AMER MEZIANE
m [email protected]
S +33 3.22.45.60.00 - Fax: +33 3.22.45.53.38
ARC/TEC CeNGEPS:
Isabelle ROUGEAUX - m [email protected]
Amélie BREANT - m [email protected]
Yacine TOURE - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
RENAL FAILURE
Network of Clinical Research for the Treatment
of Chronic Renal Failure and its Complications
Area: Cardiovascular and metabolic diseases
TARGETED PATHOLOGY/PATHOLOGIES
Chronic Renal failure (CRF) and its complications (metabolic, hematologic,
osteoarticular and cardiovascular complications)
METHODOLOGY RESOURCES
>F
rench-speaking transplantation society
>N
ephrology society
>R
enal transplantation Association for research and teaching (ASTRE)
> REIN Register: Network for Epidemiology and Information on Nephrology
>A
BMs CRISTAL register
>D
atabases of the network’s transplantation centres
kidney pyramid nephrocalcinosis /
Néphrocalcinose
INDUSTRY PARTNERS
Novartis, Roche, Astellas, Wyeth, Genzyme, Sandoz, Boehringer, Lilly…
ACTIVE PATIENT POPULATION
Patients treated and followed for a Chronic Renal Disease at all stages,
including the terminal stage when they are under dialysis or have had a
kidney transplant.
Cohort of 10,000 patients.
PARTNER DEPARTMENTS
Nephrology, haemodialysis and transplantation departments of hospital
universities in the network and general hospitals in the region.
Kidney pyramid
cross-section x 400
Human kidney, Masson-Goldner
trichrome staining
TEAMS
Project co-ordinator:
Pr Gabriel CHOUKROUN
Service de néphrologie, médecine interne,
dialyse, transplantation, réanimation
CHU d’Amiens - Hôpital Sud
Avenue René Laennec,
80054 Amiens Cedex 1
S +33 3.22.45.58.62 - Fax: +33 3.22.45.53.62
M [email protected]
Local contact people:
AMIENS
LILLE
Pr G. CHOUKROUN
m [email protected]
Pr C. NOEL
m [email protected]
Service de néphrologie, transplantation
Hôpital A. Calmette - CHRU de Lille
59037 Lille Cedex
S +33 3.20.44.41.42 - Fax: +33 3.20.44.57.81
CAEN
Pr JP RYCKELYNCK
m [email protected]
Service de néphrologie,
hémodialyse, transplantation
Hôpital Côte de Nacre
CHU de Caen
14033 Caen Cedex
S +33 2.31.27.25.76 - Fax: +33 2.31.93.23.43
ROUEN
Pr M. GODIN
m [email protected]
Service de néphrologie, transplantation
CHU de Rouen
1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.90.53 - Fax: +33 2.32.88.91.15
ARC co-ordinator:
Chacha KADI
m [email protected]
S +33 3.22.45.60.00 (ext 50562)
Fax: +33 3.22.45.54.96
ARC/TEC CeNGEPS:
Mohamed OUETHRANI
m [email protected]
Carole ZINI
m [email protected]
Marcellin BELLONET
m [email protected]
Marie-France JOINT
m [email protected]
Nephron capillary bed
(Coloured scanning electron
microscope image)
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
PAH
Network for innovative therapy for Primary Pulmonary Arterial Hypertension
Area: Cardiovascular and metabolic diseases
TARGETED PATHOLOGY/PATHOLOGIES
Primary Pulmonary Arterial Hypertension associated
with systemic diseases
INDUSTRY PARTNERS
Actélion, GSK, Pfizer, MSD…
ACTIVE PATIENT POPULATION
152 patients in Caen
141 patients in Rouen
11 patients in Amiens
110 patients in Lille
PARTNER DEPARTMENTS
Haemodynamic assessment platform (cardiac
catheterization, scintigraphy, echocardiography, cardiac
MRI)
Pneumologists, cardiologists
TEAMS
Project co-ordinator:
Pr Eric HACHULLA
Service de médecine interne
Hôpital Jeanne de Flandre
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.42.95 - Fax: +33 3.20.44.54.59
M [email protected]
Dr Pascal DE GROOTE
Service de cardiologie
Hôpital cardiologique
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.53.70 - Fax: +33 3.20.44.48.81
M [email protected]
Local contact people:
AMIENS
Pr V. JOUNIEAUX - M [email protected]
Service de pneumologie
CHU d’Amiens Nord
80054 Amiens Cedex 1
S +33 3.22.45.59.09 – Fax: +33 3.22.45.60.59
CAEN
Pr G. ZALCMAN - M [email protected]
Service de pneumologie
CHU de Caen
Hôpital Côte de Nacre, 14033 Caen Cedex
S +33 2.31.06.46.77 – Fax: +33 2.31.06.53.21
Dr E. BERGOT - M [email protected]
Pôle Coeur – vaisseaux – poumons
Hôpital Côte de Nacre – CHU de Caen
14033 Caen Cedex
S +33 2.31.06.46.77 – Fax: +33 2.31.06.53.21
LILLE
Dr E. HACHULLA - M [email protected]
ROUEN
Dr F. BAUER - M [email protected]
Service de cardiologie – CHU de Rouen
Hôpital C. Nicolle
1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.82.32 – Fax: +33 2.32.88.04.21
ARC co-ordinator:
Amandine VERHAEGHE
M [email protected]
S +33 3.20.44.50.48 ext. 29 256 – Fax: +33 3.20.44.40.62
ARC/TEC CeNGEPS:
Natacha SOBOLAK - M [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
HEART FAILURE
Area: Cardiovascular and metabolic diseases
TARGETED PATHOLOGY/PATHOLOGIES
Heart failure with a preserved ejection fraction (HFPEF)/
with a poor ejection fraction / complicated with PAH
METHODOLOGY RESOURCES
Network combining methodologists (Rouen), the various
DRCs and the network head (Rouen) in co-operation with
the investigators.
INDUSTRY PARTNERS
Biorad, Philips, General Electric, the pharmaceutical
industry (RESMED, NOVARTIS, BAYER…)
ACTIVE PATIENT POPULATION
Patients with heart failure with a preserved ejection
fraction (>200)
PARTNER DEPARTMENTS
Radiology, biology, function testing
Local contact people:
AMIENS
Pr C. TRIBOUILLOY
m [email protected]
Service de cardiologie B - Hôpital Sud - CHU d’Amiens
2 place Victor Pauchet, 80054 Amiens Cedex 1
S +33 3.22.45.58.85 - Fax: +33 3.22.45.54.58
CAEN
Pr G. GROLLIER - m [email protected]
Service de cardiologie - Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
S +33 2.31.06.44.17 - Fax: +33 2.31.06.44.18
Dr R. SABATIER - m [email protected]
Service de cardiologie - Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
S +33 2.31.06.30.50 - Fax: +33 2.31.06.44.18
LILLE
Pr C. BAUTERS - m [email protected]
Pôle cardiologie & maladies vasculaires
Hôpital cardiologique
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.50.45 - Fax: +33 3.20.44.48.81
ROUEN
Dr F. BAUER (Pr C. THUILLEZ)
m [email protected]
Collagen MRI
Collagen
Ultrasound
TEAMS
Project co-ordinator:
Dr Fabrice BAUER (Pr Christian THUILLEZ)
Unité INSERM U644
22 bd Gambetta, 76183 Rouen
S +33 2.35.14.83.68 - Fax: +33 2.35.14.83.65
m [email protected]
ARC co-ordinator:
Charlotte VALLET
m [email protected]
S +33 2.32.88.88.62 - Fax: +33 2.32.88.09.52
ARC/TEP CeNGEPS:
Ahmed RAHMANI - m [email protected]
Laëtitia DELASSUS - m [email protected]
Marie-France JOINT - m [email protected]
Mohamed OUETHRANI - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
HEPATITIS C
Area: Inflammatory and immunologic diseases
TARGETED PATHOLOGY/PATHOLOGIES
Chronic Hepatitis C (liver cancer and cirrhosis)
METHODOLOGY RESOURCES
Research network in the hepatic infectious virological area
combining hepatologists, infectiologists and virologists.
Local contact people:
INDUSTRY PARTNERS
AMIENS
Roche, Glaxo-Smith-Kline, Schering-Plough…
ACTIVE PATIENT POPULATION
Clinical centre Amiens Caen
Number of HCV
200
438
patients in 2010
Lille
200
Rouen Total
462
1300
PARTNER DEPARTMENTS
Technical platforms: molecular biology platform
Dr D. CAPRON - m [email protected]
Service d’hépatologie
CHU d’Amiens Nord - 80054 Amiens Cedex 1
S +33 3.22.66.82.07 - Fax: +33 3.22.66.82.18
CAEN
Pr T. DAO - m [email protected]
Service d’hépatologie - Hôpital Côte de Nacre
CHU de Caen - 14033 Caen Cedex
S +33 2.31.06.45.44 - Fax: +33 2.31.06.45.45
LILLE
Dr V. CANVA - m [email protected]
Service des maladies de l’appareil digestif et nutrition
Hôpital C.Huriez - CHRU de Lille - 59037 Lille Cedex
S +33 3.20.44.55.97 - Fax: +33 3.20.44.55.64
ROUEN
Pr G. RIACHI - m [email protected]
Service d’hépato-gastroentérologie et de nutrition
CHU de Rouen - 1 rue de Germont - 76031 Rouen Cedex
S +33 2.32.88.81.01 - Fax: +33 2.35.15.16.23
Severe viral
chronic hepatitis C
Severe steatosis
TEAMS
Project co-ordinator:
Pr Gilles DUVERLIE
Centre de Ressources Biologiques
CHU d’Amiens
3 rue des Louvels, 80054 Amiens Cedex 1
S +33 3.22.82.79.17 - Fax: +33 3.22.82.79.28
M [email protected]
ARC co-ordinator:
Karim DAHACHE - m [email protected]
S +33 3.22.66.80.00 ext 60077 - Fax: +33 3.22.66.79.11
ARC/TEC CeNGEPS:
Mohamed OUETHRANI - m [email protected]
Virginie SUFFYS - m [email protected]
Anthony GALLEGO - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
MICINOR
Area: Inflammatory and immunologic diseases
TARGETED PATHOLOGY/PATHOLOGIES
Chronic inflammatory intestinal diseases, Crohn’s
disease and ulcerative colitis.
METHODOLOGY RESOURCES
> Clinical investigation centres (Lille, Rouen) and BasseNormandie clinical research centre (Caen)
> Digestive Inflammatory Affection Therapeutic Study
Group (GETAID)
> INTESTINFO network
INDUSTRY PARTNERS
Shering Plough, Teva pharmaceutical, Abbott, Txcell…
ACTIVE PATIENT POPULATION
Ca. 4,000 patients with Crohn’s disease and 2,000
patients with ulcerative colitis in the active population.
PARTNER DEPARTMENTS
Pathophysiology, pharmacogenetics
Local contact people:
AMIENS
Pr J-L DUPAS - m [email protected]
Service d’hépato-gastro-entérologie
Hôpital Nord - CHU d’Amiens
Place Victor Pauchet, 80054 Amiens Cedex
S +33 3.22.66.82.14 - Fax: +33 3.22.66.82.19
CAEN
Pr J-M REIMUND - m [email protected]
LILLE
Pr J-F COLOMBEL
m [email protected]
Service des maladies de l’appareil digestif
et de la nutrition - Pôle médecine
Hôpital C. Huriez, 59037 Lille Cedex
S +33 3.20.44.53.20 - Fax : +33 3.20.44.56.82
ROUEN
Pr E. LEREBOURS - m [email protected]
Service d’hépato-gastro-entérologie et nutrition
Pôle viscéral
CHU de Rouen - Hôpital C. Nicolle
1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.81.01 - Fax: +33 2.35.15.16.23
TEAMS
Project co-ordinator:
Pr Jean-Marie REIMUND
Service d’hépato-gastro-entérologie
CHU de Caen - Hôpital Côte de Nacre
14033 Caen Cedex
S +33 2.31.06.45.41
Fax: +33 2.31.06.45.45
M [email protected]
ARC co-ordinator:
Guillaume DELAVAL - m [email protected]
S +33 2.31.06.54.32 - Fax: +33 2.31.06.45.45
ARC/TEC CeNGEPS:
Sylvie BRUCATO - m [email protected]
Catherine CUNISSE - m [email protected]
Anthony GALLEGO - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
HIV
Unité interrégionale network / AMPHORE study
Area: Inflammatory and immunologic diseases
TARGETED PATHOLOGY/PATHOLOGIES
AIDS (HIV-1 infection)
METHODOLOGY RESOURCES
>D
RCI of the 4 University Hospitals (CHUs)
>N
adis® database
> TECs as part of COREVIH
INDUSTRY PARTNERS
Boerhinger, Laboratoire Roche, Johnson & Johnson,
Gilead, MDS, Tibotec, VIIV Healthcare…
ACTIVE PATIENT POPULATION
Picardy: 1,086 patients
Lille region: 2,331 patients
Haute-Normandie: 1,077 patients
Caen CHU: 751 patients
PARTNER DEPARTMENTS
>P
icardy: CHU d’Amiens, CH d’Abbeville, CH de SaintQuentin, CH de Soissons, CH de Laon, CH de Chauny,
CH de Château-Thierry, CH de Creil, CH de Beauvais,
CHS de Clermont, CH de Compiègne, CH de Senlis,
CH de Noyon
> Lille region: CH de Tourcoing, CH de Valenciennes,
CH de Lens, CH de Boulogne, CH de Dunkerque, CH
de Douai, CHRU de Lille, maison médicale Moulins
> Normandy: CH de Dieppe, CH d’Evreux-Vernon, unité
de consultation Val de Reuil, Groupe Hospitalier du
Havre, CHU de Rouen, CHU de Caen
TEAMS
Project co-ordinator:
Dr Françoise BORSA-LEBAS
Service des maladies infectieuses et
tropicales - CHU Charles Nicolle
1 rue de Germont - 76031 Rouen Cedex
S +33 2.32.88.66.19 - Fax: +33 2.32.88.86.42
M [email protected]
Local contact people:
AMIENS
Pr JL SCHMIT - m [email protected]
Service des maladies infectieuses et tropicales
CHU d’Amiens - Place Victor Pauchet
80054 Amiens Cedex 1
S +33 3.22.66.88.13 - Fax: +33 3.22.66.88.14
CAEN
Dr S. DARGERE - m [email protected]
Service des maladies infectieuses
Hôpital Côte de Nacre - 14033 Caen Cedex
S +33 2.31.06.47.18 - Fax: +33 2.31.06.54.39
TOURCOING
Dr Eric SENNEVILLE - m [email protected]
Service régional universitaire des maladies
infectieuses et du voyageur
CH de Tourcoing - 59200 Tourcoing
S +33 3.20.69.48.48 - Fax : +33 3.20.69.46.15
ROUEN
Dr F. BORSA-LEBAS
m [email protected]
ARC co-ordinator:
Hicham SOUFI - m [email protected]
S +33 2.32.88.88.62 - Fax: +33 2.32.88.09.52
ARC/TEC CeNGEPS:
Kadidja AMRANI - m [email protected]
Mohamed OUETHRANI - m [email protected]
Mourad AGOULI - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4-3C
HEPATOCELLULAR
CARCINOMA
RICH network: Réseau des Investigateurs pour le Carcinome
Hépatocellulaire (Hepatocellular carcinoma investigator’s network) - formerly CARNOR network
Area: Cancer
TARGETED PATHOLOGY/PATHOLOGIES
Hepatocellular carcinoma
METHODOLOGY RESOURCES
National network of 41 centres treating Hepatocellular
carcinomas in France (RICH).
INDUSTRY PARTNERS
Abbott, AMGEN, Bayer, Novartis, Pfizer, Roche, …
ACTIVE PATIENT POPULATION
Estimated at 600 new patients per year
PARTNER DEPARTMENTS
Treating advanced cancers,
curing small cancers!
Imaging and biology, Hepato-Gastroenterology
dept., digestive surgery, oncology and radiotherapy,
anatomopathology, epidemiology, CyberKnife,
biostatistics unit (Amiens & Rouen University Hospitals)
TEAMS
Project co-ordinator:
Dr Jean-Claude BARBARE
DRCI, CHU Amiens Nord
1 Place Victor Pauchet
80054 Amiens Cedex 1
S +33 3.22.66.80.60
Fax : +33 3.22.66.87.52
M [email protected]
ARC co-ordinator:
Amandine BELLENGUEZ
m [email protected]
m [email protected]
S +33 3.22.66.77.33 - Mobile: +33 6.78.45.58.71
Fax: +33 3.22.66.79.11
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4-3C
THORACIC CANCER
Area: Cancer
TARGETED PATHOLOGY/PATHOLOGIES
Primary bronchial cancer and mesothelioma
METHODOLOGY RESOURCES
>R
egional co-ordination of clinical research dedicated to thoracic cancers
>N
ational anatomopathological group MESOPATH (mesothelioma BRC)
>C
o-ordination of the National Programme for the Monitoring of
Mesothelioma (PNSM)
>N
ational Register of Cancers for Calvados, Manche and Somme
>N
ational Register of Mesotheliomas, MESONAT (Pr GALATEAU-SALLE,
CHU, Caen)
>C
ancerology Clinical Research Units in the Caen University Hospital
(CHU), and the CRLCCs of Caen & Lille
bronchial tumour
>U
RC of the French-Speaking Intergroup of Thoracic Cancerology (IFCT)
INDUSTRY PARTNERS
Merck, GSK, Lilly, Roche, MSD, Sanofi-Aventis, Pierre Fabre…
ACTIVE PATIENT POPULATION
Patients suffering from bronchial cancer or mesothelioma in the NorthWest region and treated by one of the 7 teams in the network.
Cohort of workers exposed to asbestos on the work place (Haute Normandie
& Basse Normandie)
PARTNER DEPARTMENTS
Imaging and radiotherapy technical support centres (CHU and CRLCC in
Caen, Rouen, Amiens & Lille)
Pathological anatomy departments (Caen, Rouen, Amiens, Lille)
Thoracic surgery departments (Caen, Rouen, Amiens, Lille)
Nuclear medicine departments (Caen, Rouen, Amiens, Lille)
ER3 INSERM “Cancers et populations” (Pr G. LAUNOY, CHU, Caen)
Phase I Centres: CRLCC Lille, CRLCC Caen, Caen CHU
Tumour banks of Caen Basse Normandie, and Lille
Biostatistics Unit, Rouen CHU
Mesothelioma
TEAMS
Project co-ordinator:
Pr Gérard ZALCMAN
Service de pneumologie
CHU de Caen - Hôpital Côte de Nacre,
14033 Caen Cedex
S +33 2.31.06.46.77
Fax: +33 2.31.06.53.21
M [email protected]
Local contact people:
AMIENS
LILLE
Pr V. JOUNIEAUX
m [email protected]
Service de pneumologie et
réanimation respiratoire, Hôpital Sud
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.45.59.09 - Fax: +33 3.22.45.60.59
Pr A. SHERPEREEL
m [email protected]
CHRU de Lille - Hôpital Calmette,
59037 Lille Cedex
S +33 3.20.44.40.11 - Fax: +33 3.20.44.47.09
CAEN
Pr G. ZALCMAN
m [email protected]
Dr A. RIVIERE
m [email protected]
CRLCC Caen / François Baclesse
Rue du Général Harris
14076 Caen Cedex 05
S +33 2.31.45.50.13 - Fax: +33 2.31.45.50.35
ARC co-ordinnator:
Christophe ROUILLON
m [email protected]
S +33 2.31.06.57.72
or +33 2.31.06.54.37
Fax: +33 2.31.06.53.64
ARC/TEC CeNGEPS:
Ahmed RAHMANI
m [email protected]
Karim HAMON
m [email protected]
Emmanuel GIRARD
m [email protected]
Sophie DANET
m [email protected]
Carine BOYENVAL
m [email protected]
Eric WASIELEWSKI
m [email protected]
Sandrine DAMIE-DUCORNET
m [email protected]
Aurélie CLERMONT
m [email protected]
Dr E. DANSIN
m [email protected]
CRLCC Lille / Centre Oscar Lambret
Département de cancérologie générale
Rue Frédéric Combemale, BP 307,
59020 Lille Cedex
S +33 3.20.29.59.20 - Fax: +33 3.20.29.59.63
ROUEN
Pr L. THIBERVILLE
m [email protected]
Service de pneumologie - CHU de Rouen
Hôpital C. Nicolle - 1 rue de Germont,
76031 Rouen Cedex
S +33 2.32.88.82.47 - Fax: +33 2.32.88.82.40
Pr B. DUBRAY
m [email protected]
CRLCC Rouen / Centre Henri
Becquerel
Service de radiothérapie, rue
d’Amiens, 76038 Rouen Cedex 1
S +33 2.32.08.22.62 - Fax: +33 2.32.08.25.04
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4-3C
EARLY-PHASE
CLINICAL TRIALS
Early-phase (phases I - IIa) clinical trials Oncology Network
Network head labelled by InCA in 2010
Area: Cancer
TARGETED PATHOLOGY/PATHOLOGIES
Any cancer pathology: solid tumours or haematological malignancy
METHODOLOGY RESOURCES
>N
etwork relying on structures dedicated to clinical investigation
>C
o-ordination of the network integrated into a clinical research unit
> Co-operation with the data processing centre of Cancéropôle Nord-Ouest
> Participation in co-operative organisations: FNCLCC, GELA, GELARC,
GORTEC, GETTEC, IFCT, GFPC, FFCD, EORTC…
INDUSTRY PARTNERS (among other companies)
AB Science, Access Pharma, Amgen, Astra Zeneca, Boehringer Ingelheim,
BMS, Eisai, GSK, Johnson & Johnson, Lilly, Merck, Pfizer, Pierre Fabre,
Roche, Sanofi Aventis…
ACTIVE PATIENT POPULATION
>A
ny patient with a cancer pathology that has escaped standard treatment
>A
potential 150 patients per year could be included
PARTNER DEPARTMENTS
Radiology: CT scan, PET-scanner, MRI
Nuclear medicine: cardiac scintigraphy, bone scintigraphy
Clinical laboratory: anatomopathology, haematology, biochemistry,
molecular biology, oncogenetics
Fundamental research, and transfer laboratories
Tumour banks
Hospital pharmacies
TEAMS
Project co-ordinator:
Pr Florence JOLY
CRLCC Caen, Centre François Baclesse
Unité de Recherche Clinique
3 avenue du Général Harris
14076 Caen Cedex 05
S +33 2.31.45.50.02 - Fax: +33 2.31.45.50.97
M [email protected]
Local contact people:
AMIENS
LILLE
ROUEN
Dr JC BARBARE
M [email protected]
Direction de la recherche
clinique et de l’innovation
CHU d’Amiens Nord
80054 Amiens Cedex
S +33 3.22.66.80.60 - Fax: +33 3.22.66.87.52
Pr C. LIBERSA
M [email protected]
Centre d’investigation clinique
Hôpital cardiologique
CHRU Lille, 59037 Lille Cedex
S +33 3.20.44.68.91 - Fax: +33 3.20.44.68.90
Pr JP MAROLLEAU
M [email protected]
Service d’hématologie, Hôpital Sud
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.45.60.00 - Fax: +33 3.22.45.85.95
Pr M. HEBBAR
M [email protected]
Service d’oncologie médicale
Hôpital C. Huriez - CHRU Lille,
59037 Lille Cedex
S +33 3.20.44.54.79 - Fax: +33 3.20.44.50.23
Pr P. MICHEL
M [email protected]
Service d’hépato-gastro-entérologie
CHU Rouen, Hôpital Charles Nicolle
Pavillon Derocque
76031 Rouen Cedex
S +33 2.32.88.64.56 - Fax: +33 2.32.88.83.32
Pr B. CHAUFFERT
M [email protected]
Service d’oncologie médicale
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.45.54.99 - Fax: +33 3.22.45.57.43
CAEN
Pr G. ZALCMAN
M [email protected]
Centre de recherche clinique
de Basse-Normandie
CHU de Caen, avenue de la Côte
de Nacre, 14033 Caen Cedex
S +33 2.31.06.46.77 - Fax: +33 2.31.06.53.64
Pr F. JOLY
M [email protected]
Dr K. GUNZER
M [email protected]
Unité de recherche clinique
CRLCC Caen
Centre François Baclesse
3 avenue du Général Harris,
14076 Caen Cedex 05
S +33 2.31.45.50.02 - Fax: +33 2.31.45.51.58
Dr S. LHEUREUX
M [email protected]
Unité de recherche clinique
CRLCC Caen
Centre François Baclesse
3 avenue du Général Harris,
14076 Caen Cedex 05
S +33 2.31.45.50.02 - Fax: +33 2.31.45.51.58
Dr N. PENEL
M [email protected]
Oncologie médicale
Centre Oscar Lambret
Rue Frédéric Combemale
BP 307 - 59020 Lille Cedex
S +33 3.20.29.59.18 - Fax: +33 3.20.29.59.71
Pr A. ADENIS
M [email protected]
Unité de recherche clinique
CLCC Lille, Centre Oscar Lambret,
3 rue Frédéric Combemale
BP 307, 59020 Lille Cedex
S +33 3.20.29.59.59 - Fax: +33 3.20.29.59.71
ARC co-ordinator:
Emmanuel GIRARD
M [email protected]
S +33 2.31.45.50.02
Fax: +33 2.31.45.51.58
Pr H. TILLY
M [email protected]
CRLCC, Centre Henri Becquerel
Rue d’Amiens
76038 Rouen Cedex 1
S +33 2.32.08.22.22 - Fax: +33 2.32.08.22.70
Dr O. BREHAR
M [email protected]
Service d’hématologie
CLCC Rouen
Centre Henri Becquerel,
rue d’Amiens, 76038 Rouen Cedex 1
S +33 2.32.08.22.20 - Fax: +33 2.32.08.25.69
Dr C. MOLDOVAN
M [email protected]
Service oncologie
Centre Henri Becquerel,
rue d’Amiens
76038 Rouen Cedex 1
S +33 2.32.08.24.64 - Fax: +33 2.32.08.25.01
ARC/TEC CeNGEPS:
Sandrine DAMIE-DUCORNET
M [email protected]
Sabine LORIVEL
M [email protected]
Aurélie CLERMONT
M [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4-3C
SARCOMAS
Area: Cancer
TARGETED PATHOLOGY/PATHOLOGIES
Sarcomas in adults
METHODOLOGY RESOURCES
Network including the inter-region’s departments
involved in the treatment of sarcomas.
INDUSTRY PARTNERS
Bayer, Novartis, Pharmamar, Sanofi Aventis, Ariad/
Merck, Infinity, Pfizer, Amgen, IDM Pharma, Celgene,
Roche…
ACTIVE PATIENT POPULATION
398 patients with soft tissue and bone sarcomas in 2008,
with the exception of GISTs
PARTNER DEPARTMENTS
> Imaging and radiotherapy technical support centres
> Anatomy pathology departments
> Anatomy pathology & biomolecular departments:
Inter-regional expert centres (RReps)
> Hospital pharmacies
> Chemotherapy
ARC co-ordinator:
Pauline SMIS - M [email protected]
S +33 3.20.29.59.35 (poste 6808) - Fax : +33 3.20.29.59.71
ARC/TEC CeNGEPS:
Sophie DANET - M [email protected]
Sabine LORIVEL - M [email protected]
TEAMS
Project co-ordinator:
Dr Nicolas PENEL
Oncologie médicale
Centre Oscar Lambret
Rue Frédéric Combemale - BP 307
59020 Lille Cedex
S +33 3.20.29.59.18 - Fax: +33 3.20.29.59.71
M [email protected]
Local contact people:
AMIENS
Pr C. KRZISCH - M [email protected]
Oncologie - Hôpital Sud
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.45.56.40 - Fax: +33 3.22.82.54.26
Pr A. GABRION - M [email protected]
Service d’orthopédie - traumatologie - Hôpital Sud
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.66.83.10 - Fax: +33 3.22.61.81.00
Pr B. CHAUFFERT - M [email protected]
Oncologie médicale - Hôpital Sud
CHU d’Amiens, 80054 Amiens Cedex
S +33 3.22.45.54.99 - Fax: +33 3.22.45.56.76
CAEN
Pr C. VIELPEAU - M [email protected]
Service d’orthopédie - hôpital Côte de Nacre
CHU Caen, 14033 Caen Cedex
S +33 2.31.06.46.61 - Fax: +33 2.31.06.48.91
Dr C. DELCAMBRE-LAIR - M [email protected]
CRLCC Caen / CAC François Baclesse - Oncologie
Rue du Général Harris, 14076 Caen Cedex 05
S +33 2.31.45.50.30 - Fax: +33 2.31.45.50.80
LILLE
Pr C. MAYNOU - M [email protected]
Service orthopédie - hôpital Roger Salengro
CHRU Lille, 59037 Lille Cedex
S +33 3.20.44.68.00 - Fax: +33 3.20.44.67.71
Dr N. PENEL - M [email protected]
ROUEN
Pr F. DUJARDIN - M [email protected]
Service d’orthopédie - CHU de Rouen
Hôpital C. Nicolle, 1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.80.63 - Fax: +33 2.32.88.83.17
Dr C. GUILLEMET - M [email protected]
CRLCC Rouen - CAC Centre Henri Becquerel
Oncologie - Rue d’Amiens, 76038 Rouen Cedex 1
S +33 3.32.08.22.41 - Fax: +33 3.32.08.25.01
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4-3C
DIGESTIVE
ONCOLOGY
CANDI network: CANcérologie DIgestive
Area: Cancer
TARGETED PATHOLOGY/PATHOLOGIES
Cancer of the oesophagus, of the stomach, of the
pancreas, metastases of colorectal cancer
METHODOLOGY RESOURCES
Cyberknife Nord-Ouest
INDUSTRY PARTNERS
AB Science, Roche…
ACTIVE PATIENT POPULATION
437 patients potentially included each year
PARTNER DEPARTMENTS
> Surgical teams, radiologists, anatomical pathologists
> Imaging, nuclear medicine and chemotherapy
ARC co-ordinator
Anthony GALLEGO
M [email protected]
S +33 2.32.88.82.55 - Fax: +33 2.35.15.16.23
ARC/TEC CeNGEPS:
Christophe ROUILLON - M [email protected]
Edith LESIEU - M [email protected]
Justine LEROOY - M [email protected]
Aurélie CLERMONT - M [email protected]
TEAMS
Project co-ordinator:
Pr Pierre MICHEL
Service d’hépato-gastro-entérologie
Hôpital Charles Nicolle
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.86.10
Fax: +33 2.35.15.16.23
M [email protected]
Local contact people:
AMIENS
Pr JL DUPAS - M [email protected]
Service d’hépato-gastro-entérologie - CHU d’Amiens Nord
Place Victor Pauchet, 80054 Amiens Cedex 1
S +33 3.22.66.82.14 - Fax: +33 3.22.66.82.19
CAEN
Pr T. DAO - M [email protected]
Service d’hépato-gastro-entérologie
Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
S +33 2.31.06.45.44 - Fax: +33 2.31.06.45.45
Dr JH JACOB - M [email protected]
CRLCC Caen / François Baclesse
Rue du Général Harris, 14076 Caen Cedex 05
S +33 2.31.45.50.16 - Fax: +33 2.31.45.50.83
LILLE
Pr M. HEBBAR - M [email protected]
Service d’oncologie médicale - Hôpital Huriez
CHRU Lille, 59037 Lille Cedex
S +33 3.20.44.54.79 - Fax: +33 3.20.44.50.23
Pr A. ADENIS - M [email protected]
CRLCC Lille / Centre Oscar Lambret
Rue Frédéric Combemale, BP 307, 59020 Lille Cedex
S +33 3.20.29.59.35 - Fax: +33 3.20.29.59.36
ROUEN
Dr I. IWANICKI-CARON
M [email protected]
Service d’hépato-gastro-entérologie
CHU de Rouen - Hôpital C. Nicolle
1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.81.01 - Fax: +33 2.35.15.16.23
Dr A. BENYOUCEF - M [email protected]
CRLCC Rouen / Centre Henri Becquerel
Service de radiothérapie
Rue d’Amiens, 76038 Rouen Cedex 1
S +33 2.32.08.22.22 - Fax: +33 2.32.08.22.70
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4-3C
UROLOGIC
ONCOLOGY
RECH-URO-G4 network
Area: Cancer
TARGETED PATHOLOGY/PATHOLOGIES
Urologic tumours (kidney, bladder, prostate)
METHODOLOGY RESOURCES
> Network relying on the urology departments of the
4 University Hospitals (CHUs) and the oncology
departments of the 3 Cancer-fighting Centres (CLCCs)
> Common database containing patients with a urological
tumour
INDUSTRY PARTNERS
Glaxo-Smith-Kline, IPSEN, Steba biotech, Novartis,
Allergan, Astellas, Pfizer, Sanofi, Wilex, AstraZeneca,
Takeda…
PARTNER DEPARTMENTS
Imaging, nuclear medicine and chemotherapy
ARC co-ordinator:
Rassa PEGAHI - M [email protected]
S +33 2.32.88.13.15 - Fax: +33 2.32.88.14.84
ARC/TEC CeNGEPS:
Ahmed RAHMANI - M [email protected]
Sophie DANET - M [email protected]
Dina BERT - M [email protected]
Edith LESIEU - M [email protected]
Aurélie CLERMONT - M [email protected]
TEAMS
Project co-ordinator:
Pr Christian PFISTER
Service d’urologie
Hôpital Charles Nicolle
CHU Rouen, 76031 Rouen Cedex
S +33 2.32.88.81.63 - Fax: +33 2.32.88.04.41
M [email protected]
Local contact people:
AMIENS
Pr F. SAINT - M [email protected]
Service d’urologie et transplantation
CHU d’Amiens Nord, 80054 Amiens Cedex 1
S +33 3.22.45.59.52 - Fax: +33 3.22.45.57.91
Dr C. PIPROT - M [email protected]
Service d’oncologie
CHU d’Amiens Nord, 80054 Amiens Cedex 1
S +33 3.22.45.54.99 - Fax: +33 3.22.45.57.43
CAEN
Pr H. BENSADOUN - M [email protected]
Service d’urologie
Hôpital Côte de Nacre, 14033 Caen Cedex
S +33 2.31.06.48.44 - Fax: +33 2.31.06.49.57
Pr F. JOLY - M [email protected]
CRLCC Baclesse - Unité d’oncologie
Rue du Général Harris, 14076 Caen Cedex 5
S +33 2.31.45.50.02 - Fax: 0 +33 2.31.45.50.97
LILLE
Pr A. VILLERS - M [email protected]
Service d’urologie - Hôpital C. Huriez
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.66.13 - Fax: +33 3.20.44.51.43
Dr A. CATY - M [email protected]
CRLCC Oscar Lambret - unité d’oncologie
Rue Frédéric Combemale - BP 307, 59020 Lille Cedex
S +33 3.20.29.59.42 - Fax: +33 3.20.29.55.00
ROUEN
Dr F. DI FIORE - M [email protected]
Unité d’oncologie uro-digestive
CHU Rouen, 76038 Rouen Cedex 1
S +33 2.32.88.13.53 - Fax: +33 2.32.88.13.54
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
MULTIPLE
SCLEROSIS
Axial T2weighted
cross section
presenting
MS lesions
SEP Network
Area: Neurological & mental disorders
TARGETED PATHOLOGY/PATHOLOGIES
CAEN
Multiple sclerosis (MS)
Pr G. DEFER - m [email protected]
METHODOLOGY RESOURCES
>3
MS networks exist:
> RBN-SEP (Basse Normandie network for the
treatment of MS)
> RES-SEP (Eure-Seine MS network)
> G-SEP (Northern MS study & research group)
> I nter-regional neuroradiological co-operation
Pharmaceutical companies: Biogen Idec, Genmab,
Genzyme, Lilly, Lundbeck, Merck Serono, Novartis,
Peptimmune, Sanofi Aventis, Bayer Schering Pharma,
Teva, Roche…
CROs: Covance, i3 research, PRA, Quintiles, PPD,
Thérapharm…
ACTIVE PATIENT POPULATION
RR
900
2,300
750
PP
250
200
SP
350
1,000
250
Dr N. DERACHE - m [email protected]
Service de neurologie - Niveau 13
CHU de Caen
Hôpital Côte de Nacre
14033 Caen Cedex
S +33 2.31.06.46.21 - Fax: +33 2.31.06.46.27
LILLE
Pr P. VERMERSCH - m [email protected]
Service de neurologie générale et pathologie
Hôpital Salengro
59037 Lille Cedex
S +33 3.20.44.57.65 - Fax: +33 3.20.44.44.84
INDUSTRY PARTNERS
Centre
Caen
Lille
Rouen
Local contact people:
Cohort
1,500
3,500
1,000
PARTNER DEPARTMENTS
Multimodal technical platforms: MRI, CIC, CRC
TEAMS
Project co-ordinator:
Pr Gilles DEFER
Service de neurologie - CHU de Caen
Hôpital Côte de Nacre
14033 Caen Cedex
S +33 2.31.06.46.21 - Fax: +33 2.31.06.46.27
M [email protected]
ROUEN
Pr D. HANNEQUIN - m [email protected]
Département de neurologie
CHU de Rouen
76031 Rouen Cedex
S +33 2.32.88.87.40 - Fax: +33 2.32.88.87.41
Dr L. IASCI - m [email protected]
Service de pédiatrie néonatale et réanimation
CHU de Rouen
Hôpital C. Nicolle
1 rue de Germont
76031 Rouen Cedex
S +33 2.32.88.82.62 - Fax: +33 2.32.88.01.24
ARC co-ordinator:
Arnaud LEROUX - m [email protected]
S +33 2.31.06.52.94 - Fax: +33 2.31.06.46.27
ARC/TEC CeNGEPS:
Rachida MAKOURI - m [email protected]
Hicham SOUFI - m [email protected]
Laurence BELLENGIER - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
ALZHEIMER
Area: Neurological & mental disorders
TARGETED PATHOLOGY/PATHOLOGIES
Alzheimer’s Disease and Related Diseases
METHODOLOGY RESOURCES
> Inter-regional network of memory clinics
>C
ohorts of patients
> 4 complementary Memory Resource & Research Centres
(CMRR)
>N
ational Reference Centre for younger patients
INDUSTRY PARTNERS
Bayer, Bioprojet, Bristol-Myers-Squibb, Eisai, Exhonit
Therapeutics, GlaxoSmithKline, IPSEN, Janssen, Lundbeck,
Medivation, Neurochem, Novartis, Roche, Sanofi-Aventis,
Servier, Wyeth-Elan…
ACTIVE PATIENT POPULATION
6,000 cases of Alzheimer disease in the inter-region
PARTNER DEPARTMENTS
> Technical support centres and local laboratories:
structural (CT Scan, 1.5 & 3T MRI) and functional (TEMP,
PET) imaging, neuropsychology, biochemistry (CSF
biomarkers) and molecular biology, clinical genetics and
neuropathology centre
> 4 Clinical Investigation Centre (CIC) and 1 Biological
Resource Centre (CRB)
>A
natomopathological confirmation of clinical diagnoses
>P
artnership with family association
TEAMS
Project co-ordinator:
Pr Florence PASQUIER
Centre Mémoire de Ressources
et de Recherche (CMRR)
Hôpital R. Salengro
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.60.21
Fax: +33 3.20.44.60.22
M [email protected]
Local contact people:
CAEN
Dr Vincent DE LA SAYETTE
m [email protected]
Centre Mémoire de Ressources et de Recherche
(CMRR)
Hôpital Côte de Nacre, 14033 Caen Cedex
S +33 2.31.06.46.25 - Fax: +33 2.31.06.51.16
AMIENS
Pr Olivier GODEFROY
m [email protected]
Service de neurologie
CHU d’Amiens Nord, 80054 Amiens Cedex 1
S +33 3.22.66.82.42 - Fax: +33 3.22.66.82.44
ROUEN
Pr Didier HANNEQUIN
m [email protected]
Département de neurologie
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.87.40 - Fax: +33 2.32.88.87.41
LILLE
Pr Florence PASQUIER
m [email protected]
ARC co-ordinator:
Laëtitia BREUILH - m [email protected]
S +33 3.20.44.59.62 (ext 38282) - Fax: +33 3.20.44.54.93
ARC/TEC CeNGEPS:
Marcellin BELLONET
m [email protected]
Rachida MAKOURI - m [email protected]
Violette SOREL - m [email protected]
Amandine COMMARE
m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
PARKINSON
Area: Neurological & mental disorders
TARGETED PATHOLOGY/PATHOLOGIES
Parkinson’s disease and related parkinsonian syndromes
METHODOLOGY RESOURCES
>E
xisting health care networks:
> Normandy neurologist Association
> Picardy neurologist Association
> Lille Region network of university, hospital and private
neurologists: PEP Nord 62
> Regional approved research teams:
> Amiens: Laboratoire neurosciences fonctionnelles
& pathologies, EA 4559 (director: Murielle
BOUCART)
> L ille: UMR 837 INSERM, JParc, équipe 6,
“événements moléculaires associés aux stades
précoces de la maladie de Parkinson” (director:
Pr Alain DESTEE)
> Lille: Laboratoire neurosciences fonctionnelles &
pathologies, EA 4559 (director: Murielle BOUCART)
- Université Lille Nord de France
> Rouen: CIC/CRB 0204 (director: Pr Jacques WEBER)
& INSERM U614 (director: Thierry FREBOURG)
> Caen: Unité INSERM U919 (director: Pr Denis
VIVIEN)
INDUSTRY PARTNERS
Novartis Pharma, Boehringer-Ingelheim, GlaxoSmithKline,
Euthérapie, Abbott, Lundbeck, UCB Pharma, Teva, BMS,
WYETH, ADDS…
PARTNER DEPARTMENTS
Neuroradiology (MRI), clinical neurophysiology (potentials
and EEG), sleep medecine unit (polysomnography), walk
analysis system
Neuropsychologists and psychiatrists
TEAMS
Project co-ordinator:
Pr Luc DEFEBVRE
Service de neurologie A, Hôpital Salengro
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.67.30 - Fax: +33 3.20.44.66.80
M [email protected]
Local contact people:
AMIENS
Pr P. KRYSTKOWIAK
m [email protected]
Service de neurologie
CHU d’Amiens Nord, 80054 Amiens Cedex
S +33 3.22.66.82.40 - Fax: +33 3.22.66.82.44
CAEN
Pr G DEFER - m [email protected]
Service de neurologie - Niveau 13 - Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
S +33 2.31.06.46.21 - Fax: +33 2.31.06.46.27
LILLE
Pr L. DEFEBVRE - m [email protected]
Dr D. DEVOS - m [email protected]
Département universitaire de pharmacologie médicale
Faculté de médecine, 1 place de Verdun, 59045 Lille Cedex
S +33 3.20.44.54.49 - Fax: +33 3.20.44.68.63
Pr Alain DESTEE - m [email protected]
Service de neurologie et pathologie du mouvement
Hôpital Salengro, 59037 Lille
S +33 3.20.44.67.52 - Fax: +33 3.20.44.66.80
ROUEN
Dr D. MALTETE - m [email protected]
Service de neurologie
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.67.49 - Fax: +33 2.32.88.84.22
ARC co-ordinator:
Francine NISET - m [email protected]
Tel: +33 3.20.44.67.52 (ext 32313) - Fax: +33 3.20.44.67.26
ARC/TEC CeNGEPS:
Marcellin BELLONET
m [email protected]
Rachida MAKOURI - m [email protected]
Ingrid FAUCOMPRE - m [email protected]
Amandine COMMARE
m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / SIRENE NETWORK / G4
NEUROVASCULAR
Network: SIRENE (Stroke Inter REgional NEtwork)
Area: Neurological & mental disorders
TARGETED PATHOLOGY/PATHOLOGIES
> Acute or chronic neurovascular pathologies (including
vascular dementia)
> Migraine and headaches
METHODOLOGY RESOURCES
> Inter-regional network combining the neurology
departments of all 4 University Hospitals (CHUs) and
3 General Hospitals
> Cohorts of patients
> Approved research teams
> Strokavenir national network
INDUSTRY PARTNERS
Sanofi Aventis, Boehringer Ingelheim, MSD, Lundbeck…
ACTIVE PATIENT POPULATION
3,000 patients per year with a CVA treated in the acute
phase and followed up to identify and treat long term
consequences (epilepsy, depression, dementia)
PARTNER DEPARTMENTS
Imaging departments, CRBs, medical laboratories
(biomarkers), medical pharmacology, France AVC
ARC co-ordinator:
Anne-Marie BORDET
M [email protected]
S +33 3.20.44.41.45 (ext 30003) - Fax: +33 3.20.44.57.11
ARC/TEC CeNGEPS:
Marcellin BELLONET
M [email protected]
Rachida MAKOURI - M [email protected]
Martine BURGEAT - M [email protected]
Hicham SOUFI - M [email protected]
TEAMS
Project co-ordinator:
Pr Didier LEYS
Service de neurologie vasculaire
Hôpital R. Salengro, CHRU de Lille
59037 Lille Cedex
S +33 3.20.44.68.13 - Fax: +33 3.20.44.60.28
m [email protected]
Local contact people:
AMIENS
Pr O. GODEFROY - M [email protected]
Service de neurologie
CHU d’Amiens Nord, 80054 Amiens Cedex 1
S +33 3.22.66.82.42 - Fax: +33 3.22.66.82.44
Dr S CANAPLE - M [email protected]
Service de neurologie
CHU d’Amiens Nord, 80054 Amiens Cedex 1
S +33 3.22.66.82.42 - Fax: +33 3.22.66.82.44
Dr C LAMY - M [email protected]
Service de neurologie
CHU d’Amiens Nord, 80054 Amiens Cedex 1
S +33 3.22.66.82.42 - Fax: +33 3.22.66.82.44
ROUEN
Pr D. HANNEQUIN - M [email protected]
Département de neurologie
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.87.40 - Fax: +33 2.32.88.87.41
Dr E. MASSARDIER - M [email protected]
Département de neurologie
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.87.40 - Fax: +33 2.32.88.87.41
Dr A. TRIQUENOT - M [email protected]
Département de neurologie
CHU de Rouen, 76031 Rouen Cedex
S +33 2.32.88.87.40 - Fax: +33 2.32.88.87.41
CAEN
Pr F. VIADER - M [email protected]
Service de neurologie - Niveau 13
Hôpital Côte de Nacre, 14033 Caen Cedex
S +33 2.31.06.46.24 - Fax: +33 2.31.06.51.16
Pr G. DEFER - M [email protected]
Service de neurologie - Niveau 13
Hôpital Côte de Nacre, 14033 Caen Cedex
S +33 2.31.06.46.24 - Fax: +33 2.31.06.51.16
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
BIOMECHANICS
OF PROSTHESES
Theme: Orthopedic traumatology
TARGETED PATHOLOGY/PATHOLOGIES
Migration and wear of articular prostheses (total
prosthesis of the primary hip following an inflammatory
or degenerative disease)
METHODOLOGY RESOURCES
>N
etwork of the orthopedic and traumatology surgery
teams in the G4
> Clinical Orthopedic Research Centre in Caen
(Roentgen Stereophotogrammetric Analysis (RSA) Medisspecials software - LEIDEN, The Netherlands)
INDUSTRY PARTNERS
Industrial contracts with SERF and Stryker
ACTIVE PATIENT POPULATION
> 18-80 year old men or women suffering from an
inflammatory or degenerative hip disease requiring
a total prosthesis of the hip
> Early indicators of the quality of the prostheses:
Analysis of stereophotogrammetric images at D7 ± 2,
6 months + 1, 12 months ± 1, 24 months ± 1
Local contact people:
AMIENS
Pr P. MERTL - m [email protected]
Service de chirurgie orthopédique
Hôpital Nord - CHU d’Amiens
Place Victor Pauchet, 80054 Amiens Cedex
S +33 3.22.66.83.10 - Fax: +33 3.22.66.84.90
CAEN
Pr C. VIELPEAU - m [email protected]
Dr B. LEBEL - m [email protected]
LILLE
Pr H. MIGAUD - m [email protected]
Service de chirurgie orthopédique
Hôpital Roger Salengro, 59037 Lille Cedex
S +33 3.20.44.68.28 - Fax: +33 3.20.44.66.07
ROUEN
Pr F. DUJARDIN - m [email protected]
Département d’orthopédie traumatique
CHU de Rouen - Hôpital C. Nicolle
1 rue de Germont, 76031 Rouen Cedex
S +33 2.32.88.80.63 - Fax: +33 2.32.88.83.17
PARTNER DEPARTMENTS
> R adiology departments for the acquisition of
stereophotogrammetric images
> Digital analysis of the stereophotogrammetric images
by the Clinical Orthopedic Research Centre of the Caen
University Hospital
TEAMS
Project Co-ordinators:
Pr Claude VIELPEAU
Pôle de l’appareil locomoteur
CHU de Caen
Hôpital Côte de Nacre, 14033 Caen Cedex
S +33 2.31.06.46.61
Fax: +33 2.31.06.48.91
M [email protected]
Dr Benoît LEBEL
M [email protected]
Project leader:
Jean-Jacques DUTHEIL - m [email protected]
S +33 2.31.06.53.51 - Fax: +33 2.31.06.53.50
ARC Network:
Sami CHAALAN - m [email protected]
S +33 2.31.06.53.52 - Fax: +33 2.31.06.53.50
Research Engineer:
Solène GOUZY - m [email protected]
S +33 2.31.06.57.71 - Fax: +33 2.31.06.53.50
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
NEONATOLOGY
Neonatology Research & Teaching Network
Theme: Neonatal paediatrics
TARGETED PATHOLOGY/PATHOLOGIES
> Hyaline membrane disease in full-term or close to
full-term children
> Premature children with hypothyroxinemia
> Microvascular endothelium and neonatal brain injuries
>C
ardiorespiratory pathology of prenatal origin
>T
he perinatal period and toxic hazards (environment,
cannabis and/or alcohol abuse)
> Follow-up of new borns with neurological risks as part
of the regional networks
METHODOLOGY RESOURCES
> G4’s “Journées paramédicales de néonatalogie”
symposium
> French National Institute of Industrial Environment
and Hazards (INERIS)
> Perinatal networks
INDUSTRY PARTNERS
CHIESI Laboratories
ACTIVE PATIENT POPULATION
Total of births for the four regions: ca. 110,000 births
per year
PARTNER DEPARTMENTS
> Paediatric nurses, midwives, psychologists and
neonatologists
> Physiologists, biologists, paediatricians, gynaecologists
and toxicologists
TEAMS
Project co-ordinator:
Pr Laurent STORME
Pôle de médecine néonatale
Hôpital Jeanne de Flandre
CHRU de Lille - 59037 Lille Cedex
S +33 3.20.44.61.99 - Fax: +33 3.20.44.62.36
M [email protected]
Local contact people:
AMIENS
Dr G. KRIM - m [email protected]
Service de médecine néonatale
CHU d’Amiens Nord, 80054 Amiens Cedex 1
Et EA 4285 UMI 01 Unité mixte INERIS
Université de Picardie Jules Verne
S +33 3.22.66.80.00
CAEN
Pr Bernard GUILLOIS - m [email protected]
Service de néonatalogie - Hôpital Côte de Nacre
CHU de Caen, 14033 Caen Cedex
Et UMR 6232, GIP CYCERON
boulevard Henri Becquerel, BP 5229
14074 Caen Cedex 5
S +33 2.31.27.25.64
LILLE
Pr L. STORME - m [email protected]
ROUEN
Pr S. MARRET - m [email protected]
Service de pédiatrie néonatale et réanimation
Centre d’éducation fonctionnelle - CHU de Rouen
Et EA 4307, Institut hospitalo-universitaire de recherche
médicale et d’innovation
Université de Rouen, 76031 Rouen Cedex
S +33 2.32.88.89.90
ARC co-ordinator:
Laurent BEGHIN - m [email protected]
S +33 3.20.44.68.91 (ext 31490) - Fax: +33 3.20.44.68.90
Céline CLAIRET - m [email protected]
S +33 3.20.44.60.58
ARC/TEC CeNGEPS:
Hakim SEBAOUI - m [email protected]
Yacine TOURE - m [email protected]
Nathalie MESTRE - m [email protected]
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
ENDOMETRIOSIS
CIRENDO Network: Cohorte Inter Régionale des Femmes Atteintes d’Endométriose
(Inter-regional cohort of women suffering from endometriosis)
Theme: Gynaecology, fertility: genital, digestive and urinary endometriosis.
TARGETED PATHOLOGY/PATHOLOGIES
Pelvic endometriosis causing pain or infertility
METHODOLOGY RESOURCES
Cohorts:
> Risk factors for the development of pelvic endometriosis, of predictive
factors of recurrence of pain after surgical treatment, of predictive factors
of postoperative fertility.
> Efficiency of postoperative medicated treatment in preventing recurrence.
> Functional consequences of techniques for the surgical treatment of
rectal endometriosis.
> Consequences of the surgical treatment of ovarian endometriomas on
fertility.
INDUSTRY PARTNERS
Ovary endometriosis
Co-operation with PlasmaSurgical SARL in the development and the
assessment of a new technique for the surgical treatment of ovarian
endometriomas through ablation using plasma energy.
Co-operation with BayerScheringPharma and Ipsen companies with a view to
therapeutic trials concerning new indications for certain existing molecules.
ACTIVE PATIENT POPULATION
Cohort of 900 women with pelvic endometriosis
PARTNER DEPARTMENTS
>P
athological anatomy departments of the Rouen, Caen, Amiens & Lille
University Hospital (CHU)
>D
igestive surgery department, urologic surgery department, pain clinic,
imaging department of the Rouen CHU
> Gynaecology departments of Elbeuf, Dieppe, Belvédère & Saint-Pierre
hospitals, and Mathilde, Saint-Hilaire et Europe private hospitals in Rouen
> Gynaecology, obstetrics and reproductive medicine, polyclinique, ClermontFerrand CHU
> Biostatistics Unit, Rouen CHU
Rectal endometriosis
TEAMS
Project co-ordinator:
Dr Horace ROMAN
Clinique gynécologique et obstétricale
CHU de Rouen
76031 Rouen Cedex
S +33 2.32.88.87.54
Fax: +33 2.35.98.11.49
M [email protected]
ARC co-ordinator:
Amélie BREANT
M [email protected]
S +33 2.32.88.88.62
Fax: +33 2.32.88.09.52
Local contact people:
LILLE
CAEN
Dr P. COLLINET
M [email protected]
Clinique de gynécologie
Hôpital Jeanne de Flandre
CHRU de Lille
59037 Lille Cedex
S +33 3.20.44.63.88
Fax: +33 3.20.44.64.32
Dr A. CHERET-BENOIST
M [email protected]
Gynécologie obstétrique
CHU de Caen
14033 Caen Cedex
S +33 2.31.27.25.33
Fax: +33 2.31.27.23.37
ROUEN
Dr H. ROMAN
M [email protected]
AMIENS
Pr P. MERVIEL
M [email protected]
Service de gynécologie,
Obstétrique et médecine
de la reproduction
CHU d’Amiens
124 rue Camille Desmoulins
80054 Amiens
S +33 3.22.53.36.62
D.I.R.C Nord Ouest : Amiens, Caen, Lille, Rouen
CLINICAL INVESTIGATION NETWORKS / G4
PAEDIATRICS
RCP - Paediatric Clinical Research network
Theme: Paediatrics
TARGETED PATHOLOGY/PATHOLOGIES
Endocrinal and phosphocalcic metabolism affections
METHODOLOGY RESOURCES
>N
ational network of paediatric CIC INSERM
(Co-ordinator: Pr Evelyne JACQZ-AIGRAIN, CIC Hôpital Robert Debré,
48 bd Serrurier, 75019 Paris - m [email protected])
>N
ational RCP (Recherche Clinique Pédiatrique) network
>R
eferring paediatricians in the main specialties
(endocrinology, gastroenterology, pneumology, neonatology, surgery...)
>P
harmacology and developmental pharmacology expertise
>E
pidemiological expertise in the G4 network
(Pr Jacques BENICHOU, biostatisticien, unité INSERM U657
d’épidémiologie, CHU Charles Nicolle, 76031 Rouen Cedex
S +33 2.32.88.89.90 - m [email protected])
>M
ethodology platform
(Dr Berhouz KASSAI - m [email protected],
S +33 4.78.78.57.74 – Fax: +33 4.78.77.69.17)
INDUSTRY PARTNERS
Ipsen Biotech, Novartis Pharma Novonordisk, Novo Nordisk, Pfizer…
ACTIVE PATIENT POPULATION
100 patients per month in the active population
PARTNER DEPARTMENTS
Phenopups research platform - Plethysmographic platform
Genetics, biochemistry, imaging (bone densitometry scan),
Biostatistics unit, Rouen CHU
TEAMS
Project co-ordinator:
Pr Eric MALLET
Pédiatrie médicale - Hôpital Charles Nicolle,
1 rue de Germont
CHU de Rouen
76031 Rouen Cedex
Tel: +33 2.32.88.81.00 - Fax: +33 2.32.88.81.88
M [email protected]
Local contact people:
AMIENS
CAEN
Pr B. BOUDAILLIEZ
m [email protected]
Service de pédiatrie
CHU d’Amiens Nord
80054 Amiens Cedex 1
S +33 3.22.66.82.66 - Fax: +33 3.22.66.87.30
Pr ML KOTTLER
m [email protected]
Département génétique
et reproduction
Hôpital Clemenceau
CHU de Caen, 14033 Caen Cedex
S +33 2.31.27.24.17 - Fax: +33 2.31.27.26.58
Dr H. BONY
m [email protected]
Service pédiatrie 1 - Hôpital Nord
1 Place Victor Pauchet
80054 Amiens Cedex 1
S +33 3.22.66.82.66 - Fax: +33 3.22.66.87.30
Pr J. BROUARD
m [email protected]
Service de pédiatrie
CHU Clemenceau, 14033 Caen Cedex
S +33 2.31.27.25.94
LILLE
Pr J. WEILL
m [email protected]
Endocrinologie pédiatrique
Hôpital Jeanne de Flandre
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.46.95 - Fax: +33 3.20.44.60.14
ARC co-ordinator
Sylvie BLASQUEZ
m [email protected]
Catherine FONTAINE
m [email protected]
S +33 2.32.88.82.17 - Fax: +33 2.32.88.83.73
ARC/TEC CeNGEPS
Laurent BEGHIN
m [email protected]
Céline CLAIRET
m [email protected]
Yacine TOURE
m [email protected]
Isabelle POPOV
m [email protected]
Pr F. GOTTRAND
m [email protected]
CIC 9301 - Hôpital Jeanne de Flandre
CHRU de Lille, 59037 Lille Cedex
S +33 3.20.44.61.26 - Fax: +33 3.20.44.66.80
ROUEN
Pr E. MALLET
m [email protected]