Auteurs

Clinical effectiveness of endometriosis treatment in adolescent girls
Abstract ID : 1513
Soumis par : Le 2016-02-23 04:54:04
Nom de la catégorie : SEUD CONGRESS
Typologie : Poster
Statut : validé
Autorisation de diffusion : Yes/Oui
------------------------------------Context
Endometriosis is the most common cause of secondary dysmenorrhea in adolescence. At laparoscopy endometriosis is
diagnosed in 45 - 70% of adolescent girls with chronic pelvic pain [1,2,3,4]. Hormone therapy is based on the ability of
drugs to induce atrophic changes in the tissues of endometrioid heterotopias.
Objective
Assessment of endometriosis treatment effectiveness in adolescent girls with combined oral estrogen-progestin
preparation containing 30 mcg ethinyl estradiol and 2 mg dienogest for 6 months in a cyclic 21-day mode.
Methods
We examined 52 adolescent girls with endometriosis, including MRI and laparoscopy.
Patients
52 adolescent girls with endometriosis
Results
Among the enrolled girls disorders of menstrual function in form of dysmenorrhea was observed in 36 girls (69.2% ±
6.4), dysmenorrhea combined with menorrhagia - in 16 (30.8% ± 6.4) girls. MRI revealed adenomyosis in 40.4% ± 6.8
(21) of cases, in 48.1% ± 6.9 (25) - endometrioid cyst, in 11.5% ± 4.4 (6) cases - combination of adenomyosis with
endometrioid cyst with diameter up to 5.0 cm. During laparoscopy in 9 (37.5%) cases endometrioid cysts were observed,
in 6 (25.0%) cases - endometrioid cysts combined with focal adenomyosis, in 9 (37.5%) cases - adenomyosis combined
with peritoneal endometriosis. After the treatment reduction of the dysmenorrhea severity was noted in 46 (88.5%)
cases, menorrhagia was reduced in 9 (56.3%) cases. Adverse events of the therapy included nausea (5 – 9.6%),
heartburn (3 – 5.8%).
Conclusions
Using of oral contraceptive containing dienogest was quite effective with minimal side effects, accompanied by decrease
in clinical symptoms of endometriosis.
References
1. Harel Z. Journal of Pediatric and Adolescent Gynecology. 2006; vol.19:no.6: 363-371
2. Propst A.M., Laufer M.R. Endometriosis in Adolescents Incidence, Diagnosis and Treatment. J Reprod Med. 1999; 44:
751-757.
3. Laufer M.R., Goldstein D.P. Pelvic pain, dysmenorrhea and premenstrual syndrome. Pediatric and Adolescent
Gynecology.1998;4: 363-410.
4. A. Adamian L., Kulakov VI, Andreev, EN Endometriosis. Medicine, 2006; 416 p.
------------------------------------Mots clefs : endometriosis treatment, adolescent
Auteurs :
Références : , , ,
Auteurs
Gulzhachan Omarova 1, Shynar Saduakassova 1, Sh Begniyazova 1, Sholpan Aliyeva 1,
1. Gynecological, Kazakh National Medical University named by S.D. Asfendiyarov, Almaty, KAZAKHSTAN
Auteurs (raw format)
Omarova Gulzhachan - email : [email protected] Etablissement : Kazakh National Medical University
named by S.D. Asfendiyarov Service : Gynecological Ville : Almaty Pays : KAZAKHSTAN Présentateur : Oui
Saduakassova Shynar - email : [email protected] Etablissement : Kazakh National Medical University
named by S.D. Asfendiyarov Service : Gynecological Ville : Almaty Pays : KAZAKHSTAN Présentateur : Non
Begniyazova Sh - email : [email protected] Etablissement : Kazakh National Medical University named
by S.D. Asfendiyarov Service : Gynecological Ville : Almaty Pays : KAZAKHSTAN Présentateur : Non
Aliyeva Sholpan - email : [email protected] Etablissement : Kazakh National Medical University named
by S.D. Asfendiyarov Service : Gynecological Ville : Almaty Pays : KAZAKHSTAN Présentateur : Non