research grants 2014-2015
Transcription
research grants 2014-2015
NAME AGENCY JGH Totals (External grants & career awards) Medicine Totals (External grants & career awards) Medicine - Totals Students Operating Grants & Awards AFILALO, Jonathan AFILALO, Jonathan Fondation des maladies du coeur du Canada (FMCC) Fonds de la recherche en santé du Québec (FRSQ) AFILALO, Jonathan Fonds de la recherche en santé du Québec (FRSQ) AFILALO, Jonathan Fonds de la recherche en santé du Québec (FRSQ) AFILALO, Jonathan Instituts de recherche en santé du Canada (IRSC) Fonds de la recherche en santé du Québec (FRSQ) AFILALO, Marc Morand, Grégoire AFILALO, Marc AGULNIK, Jason ALAOUI-JAMALI, Moulay Merchavy, Shlomo Morand, Grégoire ALAOUI-JAMALI, Moulay ALAOUI-JAMALI, Moulay Alkailani, Maisa Ismael GH ALAOUI-JAMALI, Moulay Alkailani, Maisa Ismael GH ALAOUI-JAMALI, Moulay ALAOUI-JAMALI, Moulay ALAOUI-JAMALI, Moulay ALAOUI-JAMALI, Moulay ASSOULINE, Sarit CHU, Tsz Wai MANCINI, Johanna MacNeil, Deanna MANCINI, Johanna CHU, Tsz Wai AUTEXIER, Chantal AUTEXIER, Chantal AUTEXIER, Chantal AUTEXIER, Chantal AUTEXIER, Chantal GOLABI, Nahid AUTEXIER, Chantal AUTEXIER, Chantal AUTEXIER, Chantal AUTEXIER, Chantal AUTEXIER, Chantal GRANTS AND BURSARIES APRIL 1, 2014 - MARCH 31, 2015 TITLE Regroupement de particuliers Jewish Hospital Foundation Recherche suisse contre le cancer (RSC) Crown Family Philanthropies Recherche suisse contre le cancer (RSC) Qatar National Research Fund (QNRF) Qatar National Research Fund (QNRF) Fondation du cancer du sein du Québec Measurements of frailty to identify high-risk elderly patients referred for surgical and transcatheter aortic valve replacement. Mesure de la fragilité pour identifier les patients âgés à haut risque de complications après un remplacement valvulaire aortique chirurgical ou percutané Mesure de la fragilité pour identifier les patients âgés à haut risque de complications après un remplacement valvulaire aortique chirurgical ou percutané Mesure de la fragilité pour identifier les patients âgés à haut risque de complications après un remplacement valvulaire aortique chirurgical ou percutané Measurement of frailty to identify high-risk elderly patients referred for surgical and transcatheter aortic valve replacement Utilisation des services médicaux d'urgence et hospitaliers chez la clientèle âgée de 75 ans et plus : Quel est l'impact de l'accès aux ressources médicales et communautaires de première ligne ? Emergency Department Research. LunGevity Pulmonary Oncology Research. Identifying novel markers of oral cancer progression. External Grants Career Awards 39,075,596 27,568,152 27,568,152 Clinical Research Awards 5,124,688 4,174,821 4,174,821 188,000 188,000 11,126 22,778 1,236 7,527 91,626 1,598 510,706 90,317 5,806 Research of exosomes in tongue cancer. Identifying novel markers of oral cancer progression. Investigation of Novel Therapeutic Targets for Inflammatory Breast Cancer Investigation of Novel Therapeutic Targets for Inflammatory Breast Cancer Études précliniques de molécules anti-métastatiques capables de reprogrammer des cellules invasives du cancer du sein exprimant des marquers EMT/cellules souches. Société de recherche sur le Optimization of novel therapeutic approach targeting breast cancer cell canacer Inc plasticity and epithelial-to-mesenchymal transition for metastatic breast cancer. Instituts de recherche en santé du Investigation of the filamin signaling network's function in cancer Canada (IRSC) progression. Fonds de la recherche en santé du Des interventions pharmacologiques innovantes ciblant la transcription Québec (FRSQ) et la traduction génique entraîneront des réponses significatives dans le traitement des tumeurs lympho-myéloïdes malignes : proposition de deux essais cliniques, qui font le pont entr Université McGill Characterization of the insertion finger domain of telomerase. Fondation Cole Telomerase associated proteins Université McGill Telomerase regulation by sumoylation. Fondation Cole Telomerase associated proteins Fonds de la recherche en santé du Charactérisation d'un domaine unique (Insertion in Fingers Domain) de Québec (FRSQ) la transcriptase inverse télomérase dans le maintient des télomères, la survie cellulaire et son implication dans la maladie de la dyskératose congénitale. Fonds de la recherche en santé du Caractérisation des mécanismes controllant la recombinaison Québec (FRSQ) télomérique et la survie des cellules cancéreuses Instituts de recherche en santé du 2nd Canadian Symposium on Telomeres and Genome Integrity Canada (IRSC) Institut de recherche de la Société A haploid genetic screen in human cells to identify genes regulating canadienne du Cancer (IRSCC) chromosome end protection. Université McGill Telomerase regulation. Instituts de recherche en santé du Telomerase regulation. Canada (IRSC) 5,743,324 2,927,850 2,927,850 Industrial Contracts 20,604 24,153 50,545 55,861 30,907 112,912 140,132 8,940 956 5,440 8,154 16,560 18,407 20,000 3,813 16,209 32,212 133,429 1 BARON, Murray Regroupement de compagnies, corporations BARON, Murray Regroupement de compagnies, fondations et particuliers (Canada) BATIST, Gerald Fonds de la recherche en santé du Québec (FRSQ) Sir Mortimer B. Davis - Hôpital Général Juif Princess Margaret Hospital Foundation (The) Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Hoffmann-La Roche Limitée, Canada Instituts de recherche en santé du Canada (IRSC) Regroupement de particuliers Consortium de recherche en oncologie clinique (Q-CROC) Génome Québec Institut de recherche Terry Fox (IRTF) Regroupement de particuliers Fonds de recherche du Québec Société et culture (FRQSC) École nationale d'administration publique (ÉNAP) National Center for Geriatrics and Gerontology (The) (NCGG) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Université de Montréal BATIST, Gerald BATIST, Gerald BATIST, Gerald BATIST, Gerald BATIST, Gerald BATIST, Gerald BATIST, Gerald BATIST, Gerald BATIST, Gerald NEGOITA, Bogdan BATIST, Gerald BELAND, François Lepage, Annick BELAND, François Tsujimoto, Masashi BELAND, François BELAND, François BELAND, François BELAND, François BERGMAN, Howard BERGMAN, Howard BERGMAN, Howard BERGMAN, Howard BERGMAN, Howard MEHDI, Tahiri BERGMAN, Simon BERGMAN, Simon BERGMAN, Simon BERGMAN, Simon BERGMAN, Simon BERGMAN, Simon Saliba, James BLANK, Volker DODARD-FRIEDMAN, Isadore KANNAN, Meenakshi Bhairavi BLANK, Volker BLANK, Volker Instituts de recherche en santé du Canada (IRSC) Fonds de recherche du Québec Santé (FRQS) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Université McGill 56,170 A multicenter, open label study to describe the safety of daily subcutaneous injections of Anakinar (r-metHuIL-1ra) in patients with rheumatoid arthritis. Canadian Scleroderma Research Group. 60,450 Axe thérapies expérimentales / Réseau de recherche sur le cancer 3,163 2009 Ride to Conquer Cancer 21,000 Ride 2009, 2010 Royalty Collaborative Research. 35,000 Segal Research Coordination 100,000 WINTHER Trial - WIN (Worldwid Innovative Network: For Personalized Medicine. Novel strategy to selectively target tumor cell growth and chemosensitivity. Translational Research Center. (Q-CROC-01) - PMPC - Projet mobilisateur: Partenariat pour la médicine personnalisée en cancer du Québec. Réseau en soins de santé personnalisés Q-CROC. Pan-Canadian colorectal cancer consortium (C4) - phase I. 100,000 Oncology Research. Technology use and knowledge transfer. L'évolution conjointe du professionnalisme et de l'organisation des soins dans le contexte du Centre Segal sur le cancer. The methodology comparison of longitudinal study between Canada and Japan. Veillissement et les maladies chroniques de RUIS McGill (Réseau Universitaire Intégré de Santé McGill). Canadian Longitudinal Study on Aging (CLSA) - Mobility Initiative (CMI) An Emerging Team in Mobility in Aging Évaluation des interventions individuelles et sociétales pour promouvoir le vieillissement actif Canadian Longitudinal Study on Aging (CLSA) - Mobility Initiative (CMI) An Emerging Team in Mobility in Aging Plan d'action ministériel sur les troubles cognitifs liés au vieillissement: une évaluation de l'implantation et des résultats des projets initiaux en vue d'une généralisation progressive au Québec. Assessing care models implemented in primary health care for persons with Alzheimer's disease and related disorders Canadian Longitudinal Study on Aging (CLSA) ou Étude longitudinale canadienne sur le vieillissement (ELCV) suite du projet 41901 Canadian Consortium on Neurodegeneration in Aging - Full Proposal Understanding surgical recovery in elderly patients and its association with quality care. Fonds de la recherche en santé du Optimisation de la qualité des soins et du rétablissement chirurgical Québec (FRSQ) chez les personnes âgées Research Foundation Sir Mortimer Surgical research. B. Davis, Jewish General Hospital Hôpital Saint Mary's, Montréal Understanding the association between perioperative recovery processbased quality indicators and surgical recovery in the elderly. Instituts de recherche en santé du Assessing care models implemented in primary health care for persons Canada (IRSC) with Alzheimer's disease and related disorders Instituts de recherche en santé du Understanding surgical recovery in elderly patients and its association Canada (IRSC) with quality of care. Société d'entreprise et de gestion Role of CNC and Maf transcription in mammalian gene regulation, (SEG) (Liban) stress response and tumorigenesis. Université McGill The role of the NFE2L3 transcription factor in breast cancer. Université McGill Role of Nrf3 transcription factor in carcinogenesis. 153,556 157,368 645,967 721,052 1,101,794 1,765,807 797 4,368 8,820 284 371 696 1,238 9,693 45,499 65,300 194,964 15,055 25,374 8,000 22,600 38,999 212,214 2,102 5,011 6,989 2 BURY, Marina BLANK, Volker Université McGill BLANK, Volker BLANK, Volker BLANK, Volker Société canadienne du Cancer Société canadienne du Cancer Fondation du cancer du sein du Québec Instituts de recherche en santé du Canada (IRSC) Fondation des Maladies du Coeur du Québec Bayer Canada Inc. Instituts de recherche en santé du Canada (IRSC) Fondation des maladies du coeur du Canada (FMCC) Instituts de recherche en santé du Canada (IRSC) National Institutes of Health (NIH) (USA) BLANK, Volker BLOSTEIN, Mark BLOSTEIN, Mark BLOSTEIN, Mark BLOSTEIN, Mark RONCERO, Carlos RONCERO, Carlos Role of the transcription factor NFE 2L3 in cellular stress response and tumorigenesis. Novel regulatory pathways controlling hematopoietic stem cell fate. Novel regulatory pathways controlling hematopoietic stem cell fate. Contrôle de l'invasion de cellules de sein cancéreuses par des facteurs de transcription de type CNC. Regulation and function of NFE2L3: Linking transcription factor activity to carcinogenesis. Prospective cohort study on the safety of peri-operative management of dabigatran. Treatment of DVT, PE and SPAF. Pharmacogenomic Study of Warfarin. Role of gas6 and inflammation in the pathophysiology of venous thromboembolism. BLOSTEIN, Mark Plane-wave quantitative ultrasound imaging of blood mechanical properties BLOSTEIN, Mark U01HL087229 - Bridging anticoagulation in patients who Require temporary Interruption of warfarin therapy for an elective invasive proceDure or surGEry(BRIDGE) trial. BLOSTEIN, Mark Fondation des maladies du coeur Role of gas6 and inflammation in the pathophysiology of venous du Canada (FMCC) thromboembolism. BORCHERS, Christoph Université McGill The Segal McGill Chair in Molecular Oncology at McGIll University and the Jewish General Hospital. BORCHERS, Christoph Université McGill The Segal McGill Chair in Molecular Oncology at McGIll University and the Jewish General Hospital. BORCHERS, Christoph Université McGill The Segal McGill Chair in Molecular Oncology at McGIll University and the Jewish General Hospital. BORCHERS, Christoph Sir Mortimer B. Davis - Hôpital The Segal McGill Chair in Molecular Oncology at McGIll University and Général Juif the Jewish General Hospital. BORCHERS, Christoph Université McGill The Segal McGill Chair in Molecular Oncology at McGIll University and the Jewish General Hospital. BORCHERS, Christoph Sir Mortimer B. Davis - Hôpital The Segal McGill Chair in Molecular Oncology at McGIll University and Général Juif the Jewish General Hospital. BOUTROS, Marylise Institut de Recherche du Centre Natural history of diverticular abscess managed with non-operative Universitaire de Santé de McGill intent. CHALIFOUR, Lorraine Fondation des Maladies du Coeur Endocrine disruptor re-programming of the heart: mechanism and du Québec implications for the progression to disease. CHEN-TOURNOUX, Annabel Instituts de recherche en santé du MITNEC B5: Non-isotope based imaging modalities vs 99mTc SPECT Canada (IRSC) myocardial perfusion imaging (MPI) to detect myocardial ischemia in patients at high risk for ischemic cardiovascular events. CHERTKOW, Howard Société Alzheimer du Canada Anomia in Alzheimer's disease: what causes an inability to name objects and how could the situation be improved? CHERTKOW, Howard Société Alzheimer du Canada Anomia in Alzheimer's disease: what causes an inability to name objects and how could the situation be improved? CHERTKOW, Howard Société Parkinson Canada Comparing the nature and evolution of Mild Cognitive Impairment in individuals with and without Parkinson's disease CHERTKOW, Howard Instituts de recherche en santé du Comparing the nature and evolution of Mild Cognitive Impairment in Canada (IRSC) individuals with and without Parkinson's disease CHERTKOW, Howard Fonds de la recherche en santé du Consortium pour l'identification précoce de la Maladie d'Alzheimer Québec (FRSQ) Québec (CIMA-Q). CHERTKOW, Howard Instituts de recherche en santé du Canadian Consortium on Neurodegeneration in Aging. Canada (IRSC) CHERTKOW, Howard Instituts de recherche en santé du CCNA Agreement 1393: KT activities carried out by the CCNA Canada (IRSC) knowledge transfer cross-cutting program CCP. (Dalhousie University, Halifax, Nova Scotia - Ken Rockwood) CHERTKOW, Howard Instituts de recherche en santé du H. Chertkow-Expession of interest for CCNA. Canada (IRSC) CHERTKOW, Howard Instituts de recherche en santé du CCNA Agreement 1391: Issues in rural dementia care. (University of Canada (IRSC) Saskatchewan, Saskatoon, College of Nursing, Saskatoon, Saskatchewan -Debra Morgan). CHERTKOW, Howard Alberta Prion Research InstituteCCNA Agreement 1388: Protein misfolding, sub-project 3D. (The Alberta Ingenuity Alberta Innovates - Bio Solutions (AI-Bio) - The Alberta Prion Research Institute (APRI) - Andriy Kolavenko) 15,055 14,881 83,791 86,302 136,772 2,139 22,000 25,000 33,874 34,849 37,866 104,255 7,418 15,082 4,932 14,178 15,034 43,224 4,000 7,418 8,562 17,330 24,170 1,250 7,535 8,332 10,440 15,000 17,705 25,000 30,000 3 CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard COHEN, Albert Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Fonds de la recherche en santé du Québec (FRSQ) Instituts de recherche en santé du Canada (IRSC) National Institutes of Health (NIH) (USA) Weston Brain Institute Instituts de recherche en santé du Canada (IRSC) Regroupement de particuliers Instituts de recherche en santé du Canada (IRSC) QUEEN'S UNIVERSITY PENNER, Jamie COHEN, Albert COHEN, S Robin LAFOREST, Esther COHEN, S Robin BEAUCHEMIN, Antoine COHEN, S Robin Instituts de recherche en santé du Canada (IRSC) COHEN, S Robin COHEN, S Robin Réseaux de centres d'excellence du Canada (RCE) Max Bell Foundation Lu, Chang EISENBERG, Mark Université McGill Touma, Lahoud EISENBERG, Mark Harel-Sterling, Lee EISENBERG, Mark Instituts de recherche en santé du Canada (IRSC) Université McGill GRANDI, Sonia EISENBERG, Mark Instituts de recherche en santé du Canada (IRSC) EISENBERG, Mark Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) EISENBERG, Mark EISENBERG, Mark EISENBERG, Mark EISENBERG, Mark EISENBERG, Mark EISENBERG, Mark ERNST, Pierre-Paul ERNST, Pierre-Paul Vincent, Sophie FILION, Kristian Vincent, Sophie FILION, Kristian Regroupement de particuliers Instituts de recherche en santé du Canada (IRSC) Université McGill Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Université McGill Instituts de recherche en santé du Canada (IRSC) The impact of beta-amyloid burden on cognition in normal aging. 36,429 Assessing care models implemented in primary health care for persons with Alzheimer's disease and related disorders Entre le laboratoire et le chevet : validation de bio-marqueurs optimisés par résonance magnétique pour le diagnostic clinique précoce et le prognostic dans la maladie d'Alzheimer. Alzeimer's disease cooperative study - project #1. 38,999 60,000 Clinical assessment of patients with AD and NEC individuals. 89,774 Development and validation of tau protein in saliva as an indicator for early Alzheimer's Disease. Anomia in Alzeimer's Disease: Untangling sematic components and delivering therapy with rTMS. Alzheimer's Research. Canadian Consortium on Neurodegeneration in Aging - Full Proposal Integrating a quality of life asessment and practice support system in palliative homecare. Inflammatory bowel disease. Development and feasibility testing of a home-based physical activity intervention for family caregivers of people with advanced cancer. Exploring the implementation of a provisional program to train nurse champions in a cardiac palliative approach. Exploring how advanced cancer patients experience high or low existential well-being: A mixed-methods study. Integrating quality of life assessments into acute care for older adults with chronic life-limiting illness. Caring for the caregiver: Implementation of an evidence-based novel service for family caregivers of cancer patients at the end of life The safety and efficacy of ABSORB bioresorbable vascular scaffold: A systematic review. Apixaban and the risk of bleeding: a meta-analysis of randomized controlled trials. Pharmacological options for stroke prevention among patients undergoing trans-aortic valve implantation (TAVI). A population-based analysis of the trends in treatment and management of patients with acute myocardial infarction complicated by cardiogenic shock. Hypertensive Disorders in Pregnancy and the Risk of Subsequent Cardiovascular Disease Optimizing physician training in motivational communication (MC) skills for health behavior change Optimizing physician training in motivational interviewing (MI) to improve MI compentency, patient health behaviors, and morbidity among patients with cardiovascular and chronic lung disease Population Level Evaluation of Ablation Therapies in Atrial Fibrillation The efficacy and safety of smoking cessation interventions in patients with cardiovascular disease: A meta-analysis of randomized controlled trials. The clinical, regulatory, and ethical implications of electornic cigarettes: A knowledge synthesis grant. Evaluating the efficacy of E-cigarette use for smoking cessation (E3) trial. CIHR - Quebec Respiratory Health Training Program The impact of a brief motivational intervention on adherence behavior in asthmatics: A randomized controlled trial Long-term outcomes for stenting versus endarterectomy for carotid stenosis: A meta-analysis of randomized controlled trials. Long-term outcomes for stenting versus endarterectomy for carotid stenosis: A meta-analysis of randomized controlled trials. 49,984 112,720 153,303 286,562 2,526,092 4,242 36,440 4,167 11,831 19,992 5,436 31,495 1,000 2,834 3,125 35,000 35,000 4,339 4,540 17,211 49,980 91,484 161,604 8,125 11,783 2,000 2,834 4 FILION, Kristian FILION, Kristian FILION, Kristian FILION, Kristian WU, Mona FOULKES, William David WITKOWSKI, Leora FOULKES, William David WITKOWSKI, Leora WU, Mona FOULKES, William David FOULKES, William David Di Iorio, Massimo FOULKES, William David WITKOWSKI, Leora FOULKES, William David Rivera Polo, Barbara FOULKES, William David FOULKES, William David De Kock, Leanne WU, Mona FOULKES, William David FOULKES, William David FOULKES, William David Rivera Polo, Barbara FOULKES, William David ZAYED, Nadia FOULKES, William David WITKOWSKI, Leora FOULKES, William David Rivera Polo, Barbara FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David Instituts de recherche en santé du Canada (IRSC) Fonds de la recherche en santé du Québec (FRSQ) Fonds de la recherche en santé du Québec (FRSQ) Instituts de recherche en santé du Canada (IRSC) Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Sir Mortimer B. Davis - Hôpital Général Juif Société canadienne du Cancer Université McGill The cardiovascular safety of varenicline: A population-based cohort study. Une évaluation populationelle des effets cardiovasculaires indésirables des médicaments Une évaluation populationelle des effets cardiovasculaires indésirables des médicaments A population-based assessment of the cardiovascular effects of 5-alpha reductase inhibitors. DICER1 mutations occurring in childhood anaplastic sarcoma of kidney. New cases of small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). AACR Annual Meeting 2014. Towards creation of a dileri plezotropic tumour predisposition cell model. Université McGill Deciphering the role of deep-intronic variants in mutation negative DICER1-associated phenotypes. Fonds de la recherche en santé du Facteurs Génétiques du Cancer de l'Ovaire Non-Épithéliale Québec (FRSQ) Université McGill James McGill Professorship Award. Ministère de l'Éducation, du Loisir 1)Characterization of rare variants in hereditary colorectal syndromes. et du Sport (MELS) (Québec) 2) Dicer1, microRNA and childhood cancer. Université McGill James McGill Professorship Award. Université McGill DICER Research. Fonds de la recherche en santé du In vitro modelling of DICER1-linked tumours Québec (FRSQ) Fundación Alfonso Martín 1)Characterization of rare variants in hereditary colorectal syndromes. Escudero 2) Dicer1, microRNA and childhood cancer. Université McGill Suscephbilité génétique au cancer du sein dans la population canadienne québecoise. Fonds de la recherche en santé du Recherche des mutations causales dans les tumeurs rares de l'ovaire. Québec (FRSQ) Fundación Alfonso Martín 1)Characterization of rare variants in hereditary colorectal syndromes. Escudero 2) Dicer1, microRNA and childhood cancer. Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. Fonds de la recherche en santé du Simulation du coût/efficacité et du coût/utilité du dépistage des gènes Québec (FRSQ) de prédisposition au cancer du sein Instituts de recherche en santé du A research and knowledge network on genetic health services and Canada (IRSC) policy: building on the APOGEE-Net and CanGeneTest experiences. Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. National Institutes of Health (NIH) PROSTATE CANCER SUSCEPTIBILITY: THE ICPCG STUDY (USA) Ministère des relations Identification de nouveaux gènes de susceptibilité à la néoplasie internationales du Québec colorectale Université McGill James McGill Professorship Award. Société canadienne du Cancer Nomination for the Canadian Cancer Society's O. Harold Warwick Prize in Cancer Control Research Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. Génome Canada Personalised risk stratification for prevention and early detection of breast cancer. Alliance canadienne pour la Risk factor analysis of hereditary breast and ovarian cancer recherche sur le cancer du sein Identification de nouveaux gènes de susceptibilité à la néoplasie Ministère de l'enseignement colorectale supérieur, de la recherche, de la science et de la technologie (MESRST) 60,000 3,709 11,291 59,384 146 500 850 1,000 1,000 1,236 1,236 3,654 3,764 3,786 4,176 5,208 7,418 8,352 17,495 101 244 245 351 812 1,003 1,061 1,230 1,854 2,500 2,942 3,125 3,742 4,604 4,833 5 Identification de nouveaux gènes de susceptibilité à la néoplasie colorectale 5,501 James McGill Professorship Award. Identification of new colorectal cancer susceptibility genes Genome-wide approach to dissect driver pathways in small cell carcinoma of the ovary, hypercalcaemic type Axe banque de tissus et de données BTD / Réseau de recherche sur le cancer / projet "Tumeurs sein / ovaire 26380 5,646 6,355 8,288 FOULKES, William David Fonds de la recherche en santé du Axe banque de tissus et de données BTD / Réseau de recherche sur le Québec (FRSQ) cancer / projet "Tumeurs sein / ovaire 26380 8,755 FOULKES, William David Fondation du cancer du sein du Québec 9,523 FOULKES, William David Ministère de l'enseignement supérieur, de la recherche, de la science et de la technologie (MESRST) Fondation du cancer du sein du Québec FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David FOULKES, William David Alpuche Lazcano, Sergio Paulo FRIEDMAN, Ruby GATIGNOL, Anne BURUGU, Samantha GATIGNOL, Anne GATIGNOL, Anne GATIGNOL, Anne GATIGNOL, Anne GATIGNOL, Anne GATIGNOL, Anne NGOMA, Alain GREENAWAY, Christina GREENAWAY, Christina GREENAWAY, Christina GREENAWAY, Christina Ministère de l'enseignement supérieur, de la recherche, de la science et de la technologie (MESRST) Université McGill Commission Européenne Merck Sharp & Dohme Research Laboratory Fondation du cancer du sein du Québec Pratiques de dépistage du cancer des non-porteuses de mutations familiales des gènes BRCA1/2: Étendue, déterminants et impact psychosocial du sur-dépistage Identification de nouveaux gènes de susceptibilité à la néoplasie colorectale La genetique du cancer du sein dans la population quebecoise : vingt ansapres BRCA1/2 Regroupement de particuliers Surgical Research. Alex's Lemonade Stand Foundation DICER1 , microRNAs and pediatric cancer: an emerging story (USA) Institut de recherche de la Société DICER1 and pituitary blastoma: Keys to understanding pituitary canadienne du Cancer (IRSCC) development and tumorigenesis. Institut de recherche de la Société Towards a biological understanding of small cell carcinoma of the canadienne du Cancer (IRSCC) ovary, hypercalcemic type. Institut de recherche de la Société DICER1 and pituitary blastoma: Keys to understanding pituitary canadienne du Cancer (IRSCC) development and tumorigenesis. Susan G. Komen Breast Cancer hereditary Breat Cancer: Cause and Effect. Foundation (The) Alex's Lemonade Stand Foundation DICER1 , microRNAs (USA) and pediatric cancer: an emerging story Institut de recherche Terry Fox Pan-Canadian Colorectal Cancer Consortium (C4) - Phase 1 (IRTF) Susan G. Komen Breast Cancer hereditary Breat Cancer: Cause and Effect. Foundation (The) Regroupement de particuliers Geriatric Research. Consejo Nacional de Ciencia y Mechanisms of RNA interference and RNA Decay in cytoplasmic Tecnologia (CONACYT) (Mexico) granules during HIV-1 replication in monocytes. Fonds de la recherche en santé du Rôle de PKR et PACT dans l'activité de l'IFN de type I sur les Québec (FRSQ) lymphocytes T CD4+ infectés par le VIH. Instituts de recherche en santé du Virus-cell interactions in the regulation of HIV translation. Canada (IRSC) Instituts de recherche en santé du Virus-cell interactions in the regulation of HIV translation. Canada (IRSC) Instituts de recherche en santé du The Canadian HIV Cure Enterprise (CanCURE) Canada (IRSC) Instituts de recherche en santé du Exploring interactions between HIV and the RNA interference pathway. Canada (IRSC) Instituts de recherche en santé du Development of antisense-based small RNA agents targeting the GAG Canada (IRSC) open reading frame of HIV-1 RNA for use in Gene and Drug therapy against HIV-1 infection. Université McGill Estimating and comparing the burden of chronic hepatitis B infection in the Immigrant and the Quebec born population: A population based story. Fonds de recherche du Québec - Centre Interuniversitaire québécois de statistiques sociales Société et culture (FRQSC) Instituts de recherche en santé du Accessibility and costs of healthcare for refugee claimants following Canada (IRSC) changes to the Interim Federal Health Program Instituts de recherche en santé du Universal childhood Varicella vaccination program: Will it protect or Canada (IRSC) harm the immigrant population? 8,750 9,824 11,676 13,489 15,453 16,621 16,690 33,379 39,091 47,047 47,775 78,505 68,284 9,970 15,000 50,000 64,878 76,509 96,126 159,550 5,824 1,598 33,214 72,506 6 HILZENRAT, Nir HILZENRAT, Nir HIRSCH, Andrew HOFFER, Leonard J. HUDSON, Marie HUDSON, Marie HUDSON, Marie NASRAH, Rima HUDSON, Marie HUDSON, Marie JAGOE, Robert JAGOE, Robert Totten, Stephanie Weisstock, Christina JOHNSON, Nathalie JOHNSON, Nathalie JOHNSON, Nathalie Sesques, Pierre JOHNSON, Nathalie Sesques, Pierre JOHNSON, Nathalie Totten, Stephanie JOHNSON, Nathalie JOHNSON, Nathalie JOHNSON, Nathalie JOHNSON, Nathalie JOHNSON, Nathalie JOHNSON, Nathalie JOHNSON, Nathalie KADER, Tina Cohen, Jacqueline KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca Regroupement de compagnies, corporations Regroupement de compagnies, corporations Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Lotte & John Hecht Memorial Foundation Fonds de la recherche en santé du Québec (FRSQ) Fonds de la recherche en santé du Québec (FRSQ) Regroupement de compagnies, fondations et particuliers (Canada) Grifols Canada Ltd. Société de l'arthrite (La) Université McGill IMPROVE - Individualized Management with Pegasys RBV Offering Viral Eradication. Improved care and education for patients with Hepatitis B. 196,160 Intersticial lung disease (ILD). 110,675 Open clinical trial to validate a short-term vitamin D loading and maintenance dose protocol in people with advanced lung cancer. Recherches observationnelles portant sur les maladies systemiques autoimmunes rhumatismales Recherches observationnelles portant sur les maladies systemiques autoimmunes rhumatismales The 1000 Canadian faces of lupus study. Canadian inflammatory myopathy study group. 2013-14 TAS knowledge translation/networking. New approaches to optimizing nutritional interventions in oncology patients and cachexia. Instituts de recherche en santé du Multimodal exercise, nutrition and anti-inflammatory treatment for Canada (IRSC) palliation of cancer cachexia: The MENAC study. Université McGill Role of Fas mutations in chemotherapy resistent lymphomas. Université McGill Overcoming therapeutic resistance in FAS-mutant lymphomas. Fonds de la recherche en santé du Identification de biomarqueurs de prévision des lymphomes se Québec (FRSQ) présentant chez les adolescents et les jeunes adultes Agence Rhône-alpes pour les Elucidating the mechanism of therapeutic resistance in diffuse large B Sciences Humaines et Sociales cell lymphoma. Roche Diagnostics Elucidating the mechanism of therapeutic resistance in diffuse large B cell lymphoma. Instituts de recherche en santé du Role of Fas mutations in chemotherapy resistent lymphomas. Canada (IRSC) Fonds de la recherche en santé du Identification de biomarqueurs de prévision des lymphomes se Québec (FRSQ) présentant chez les adolescents et les jeunes adultes Fonds de la recherche en santé du Identification de biomarqueurs de prévision des lymphomes se Québec (FRSQ) présentant chez les adolescents et les jeunes adultes Fondation Cole Help develop the cell library of the Quebec Leukemia Cell Bank with young adult lymphoma cells. Institut de recherche de la Société Optimizing therapy for STAT6-mutant DLBC. canadienne du Cancer (IRSCC) Sir Mortimer B. Davis - Hôpital Help develop the cell library of the Quebec Leukemia Cell Bank with Général Juif young adult lymphoma cells. Instituts de recherche en santé du Overcoming therapeutic resistance in lymphoma. Canada (IRSC) Instituts de recherche en santé du The Metformin in women with type 2 diabetes in pregnancy trial ("MITY" Canada (IRSC) "The Study") Université McGill Antioxidant and lipid levels in relation to risk of preeclampsia and small for gestational age in a large cohort of pregnant women from Montreal, Canada. Chaires de recherche du Canada Venous Thromboembolism (CRC) Instituts de recherche en santé du GENErVTE: Gene Gene Interactions and Recurrent Venous Canada (IRSC) Thromboembolism. Fondation des maladies du coeur P. Wells - HSFO - Development and validation of clinical prediction ruls de l'Ontario (Toronto, Ont) for bleeding for patients on anticoagulant therapy for venous thromboembolism. Instituts de recherche en santé du A pilot study assessing feasibility of a randomized, placebo-controlled Canada (IRSC) trial of low-molecular-weight-heparin for postpartum prophylaxis in women at risk of developing venous thromboembolism (pilot PROSPER trial: PostpaRtum PrOphylaxiS for PE randomized Instituts de recherche en santé du The SOX trial; Disseminating the unexpected results of a large, CIHR Canada (IRSC) North American RCT of elastic compression stockings to prevent the post-thrombotic syndrome. National Institutes of Health (NIH) Chronic venous thrombosis: Relief with adjunctive catheter-based (USA) therapy (C-TRACT) study. Institut de Cardiologie de Montréal CIHR-ICRH CDP Application Preparation. (ICM) 3,510 95,000 9,111 28,257 1,164 7,527 10,000 309 43,774 1,670 3,125 8,751 14,042 14,043 16,106 27,219 2,473 4,121 8,088 128,864 149,722 770 5,011 100,000 210 4,195 4,480 11,272 17,490 25,000 7 Jayasundera, Thiran KAHN, Susan Rebecca Instituts de recherche en santé du Canada (IRSC) Extended venous thromboembolism prophylalis comparing rivaroxaban to aspirin following total hip and knee arthroplasty (EPCAT II) KAHN, Susan Rebecca KAHN, Susan Rebecca Sanofi-Aventis (Canada) Instituts de recherche en santé du Canada (IRSC) KAHN, Susan Rebecca KAPUSTA, Michael Pfizer Canada Inc. Sir Mortimer B. Davis - Hôpital Général Juif Instituts de recherche en santé du Canada (IRSC) Institut de recherche de la Société canadienne du Cancer (IRSCC) Regroupement de particuliers Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Fonds de la recherche en santé du Québec (FRSQ) Regroupement de particuliers Université McGill Instituts de recherche en santé du Canada (IRSC) Université McGill Thrombosis Fellowship. Randomized controlled trail of anticoagulation vs. placebo for a first symptomatic isolated distal deep-vein thrombosis (IDDVT): The CACTUS-PTS Trial. Venous Thromboembolism TD FELLOWSHIP - Dr. Jayasundera. KARAPLIS, Andrew C. KAVAN, Petr KAVAN, Petr KLEIMAN, Lawrence C. KLEIMAN, Lawrence C. KLEIMAN, Simcha CHOQUET, Karine KLEINMAN, Claudia DÉRY, Marc-André LANGLEBEN, David LEBLANC, Andréa LEBLANC, Andréa Lynham, Jeffrey LEBLANC, Andréa DÉRY, Marc-André LEBLANC, Andréa PAKAVATHKUMAR, Prateep LEBLANC, Andréa NOEL, Anastasia LEBLANC, Andréa LEBLANC, Andréa LEBLANC, Andréa LEBLANC, Andréa LEBLANC, Andréa LEBLANC, Andréa LEBLANC, Andréa LEBLANC, Andréa SIMEONE, Stefania LEBLANC, Andréa LEHOUX, Stephanie LEHOUX, Stephanie LEHOUX, Stephanie LEHOUX, Stephanie BEITARI, Saina LIANG, Chen WANG, Yimeng Liang, Zhibin LIANG, Chen LIANG, Chen LIANG, Chen LIANG, Chen PTHrP and osteoblast biology: relevance to osteoporosis Cognitive performance and psychosocial development in young adult cancer survivors: A prospective, longitudinal study. Young adult program. Formation of the tRNALys packaging complex in HIV-1. Regulation of primer tRNALys3 annealing to HIV-1 genomic RNA during HIV-1 replication. Jewish General Hospital Anesthesia Fellowship Impact transcriptionnel d'une mutation dans le gène POLR3A chez un modèle souris des leucodystrophies reliées à l'ARN polymérase III Cath lab education fund. Molecular mechanisms of neuronal cell death. Role of the cytosolic prion protein in the regulation of Bax ubiquitination and its impact on cell survival. Finding effective inhibitors for Caspase-6 which is a new target in the treatment of Alzeimer's disease. Université McGill Role of the cytosolic prion protein in the regulation of Bax ubiquitination and its impact on cell survival. Fonds de la recherche en santé du L'étude d'inhibiteurs de la Caspase-6 in vitro et in vivo pour développer Québec (FRSQ) une nouvelle stratégie thérapeutique pour la maladie Alzheimer Molecular mechanisms of neuronal cell death. Traumatisme craniocérébral léger à répétition: impact sur la pathologie tau et effets d'un agoniste LXR. Université McGill Molecular mechanisms of neuronal cell death. Université McGill Molecular mechanisms of neuronal cell death. Fonds de la recherche en santé du Nouveaux modèles de la Maladie Alzheimer dans le poisson zébré. Québec (FRSQ) Instituts de recherche en santé du Regulation of prion protein expression, trafficking and function Canada (IRSC) Instituts de recherche en santé du Role of caspases in human neuronal cell death and in Alzheimer's Canada (IRSC) Disease. Fonds de la recherche en santé du Consortium pour l'identification précoce de la Maladie d'Alzheimer Québec (FRSQ) Québec (CIMA-Q). Regroupement de particuliers Alzheimer's research funds. Fonds de la recherche en santé du Mécanismes impliqués dans la réduction de la plaque d'athérosclérose Québec (FRSQ) par la contrainte de cisaillement. Chaires de recherche du Canada Cardiovascular Physiology. (CRC) Instituts de recherche en santé du Potential roles of Semaphorin 3A in atherosclerosis. Canada (IRSC) Instituts de recherche en santé du Athero-protective shear stress signalling in the vasculature Canada (IRSC) Université McGill Identifying the interaction between HIV-1 restriction factors and nuclear pore complex. Université McGill Studying the anti-HIV activity of IFITM proteins. China Scholarship Council (CSC) Identification of anti-HIV-1 interferon-stimulated genes and mechanistic study of their antiviral activities. Instituts de recherche en santé du Fusion and cell entry by oncogenic sheep retroviruses. Canada (IRSC) Canadian Foundation for AIDS Investigate the anti-HIV-1 activity of interferon-induced MxB protein. Research (CANFAR) 70,400 75,000 142,563 250,000 45,000 82,101 1,087 13,781 74,137 100,000 67,500 5,824 1,500 797 2,576 3,495 5,824 8,280 Université McGill Société Alzheimer du Canada 9,203 31,239 1,195 13,805 50,000 142,177 156,259 158,316 336,000 1,593 50,000 124,934 127,729 2,912 7,863 15,653 28,792 40,000 8 LIANG, Chen LIANG, Chen LIANG, Chen LIANG, Chen Liu, Yiliu LIN, Rongtuan SZE, Alexandre LIN, Rongtuan LIN, Rongtuan LIN, Rongtuan LIN, Rongtuan LIN, Rongtuan LIN, Rongtuan LIN, Rongtuan LIN, Rongtuan LIPMAN, Mark L. LONGTIN, Yves LONGTIN, Yves LONGTIN, Yves LONGTIN, Yves MAC NAMARA, Elizabeth MAC NAMARA, Elizabeth Negro Silva, Luis Fernando Wu, Ting Hua (Joshua) Bolt, Alicia Marie Bolt, Alicia Marie LEMAIRE, Maryse MANN, Koren MANN, Koren MANN, Koren MANN, Koren MANN, Koren MANN, Koren MANN, Koren MANN, Koren MANN, Koren MICHEL, Caroline MICHEL, Caroline DAHABIEH, Michael PETRUCCELLI, Luca MILLER, Wilson MILLER, Wilson MILLER, Wilson Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Fonds de la recherche en santé du Québec (FRSQ) Canadian Foundation for AIDS Research (CANFAR) Cancer de la prostate Canada Instituts de recherche en santé du Canada (IRSC) Cancer de la prostate Canada Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Regroupement de particuliers Fonds de la recherche en santé du Québec (FRSQ) Studying the antiviral of bone marrow stromal cell antigen 2 and the countering mechanism from HIV-1 Vpu. Study the role of SAMHD1 in HIV-1 transmission. 75,000 Investigate the Antu-HIV-1 activity of interferon-induced MxB protein. 100,000 Study the antiviral fundtion of IFITM proteins. 123,708 Regulation of STING via the RIG-1 dependent RNA sensing pathway. Caractérisation de l'apoptose induite par les ADNs produits lors d'infections rétrovirales. Ubiquitination promotes the survival of functional HIV-specific CD4+T CM cells in elite controllers by decreasing Bim and Puma expression. Combination oncolytic virotherapy for the treatment of prostate cancer. Cross-talk between host antiviral and apoptotic signaling pathways in de novo Dengue virus infection. Combination oncolytic virotherapy for the treatment of prostate cancer. Innate immunity and Hepatitis C virus infection. Oncolytic virus therapy for HTLV-1 induced adult T cell leukemia. Manipulating the RIG-1 signaling pathway to inhibit influenza virus infection. Hemodialysis Research. - Les infections nosocomiales - Une approche globale et intégrative pour mieux comprendre et prévenir la diarrhée associée au C. difficile et améliorer l'hygiène des mains Fonds de la recherche en santé du - Les infections nosocomiales - Une approche globale et intégrative Québec (FRSQ) pour mieux comprendre et prévenir la diarrhée associée au C. difficile et améliorer l'hygiène des mains Fonds de la recherche en santé du - Les infections nosocomiales - Une approche globale et intégrative Québec (FRSQ) pour mieux comprendre et prévenir la diarrhée associée au C. difficile et améliorer l'hygiène des mains Fonds de la recherche en santé du - Les infections nosocomiales - Une approche globale et intégrative Québec (FRSQ) pour mieux comprendre et prévenir la diarrhée associée au C. difficile et améliorer l'hygiène des mains Génome Québec Clinical implementation and outcomes evaluation of blood-based biomarkers for COPD management. Génome Canada Clinical implementation and outcomes evaluation of blood-based biomarkers for COPD management. Université McGill Contribution of arsenic to enhance atherosclerosis. Université McGill Tungsten-induces alteration B lymphocytes. Fondation Cole The role of Tungsten in preB Cell Leukemogenesis. Fondation Cole The role of Tungsten in preB Cell Leukemogenesis. Instituts de recherche en santé du Mechanisms of arsenic-induced atherosclerosis. Canada (IRSC) Institut de recherche de la Société Optimizing therapy for STAT6-mutant DLBC. canadienne du Cancer (IRSCC) Leukemia & Lymphoma Society of The role of mutated Ras-associating proteins in R-CHOP-resistant Canada (The) (LLSC) DLBCL. Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) National Institutes of Health (NIH) (USA) Centre universitaire de santé McGill (CUSM) Université McGill Université McGill Instituts de recherche en santé du Canada (IRSC) 72,135 Bone as a target for Tungsten-induced toxicities. Mechanisms of arsenic-enhanced atherosclerosis. Phosphodiesterase Type 5 inhibition with Tadalafill changes outcomes in heart failure (PITCH-HF). The ACE switchback study. Mechanisms of drug resistance in melanoma and lymphoma cells. McGill James Improving combination therapies involving histone deacetylare inhibitors and DNA methyltransferare inhibitors in hematological malignancies 582 18,407 14,835 24,725 56,250 75,275 87,153 142,154 167,623 143,733 8,334 26,065 2,473 7,527 216,680 326,897 6,989 7,863 9,890 30,110 31,250 8,088 45,165 50,000 154,580 2,940 7,250 635 797 883 9 ZHAN, Yao MILLER, Wilson Kaddour, Nancy DAHABIEH, Michael ZHAN, Yao MILLER, Wilson MILLER, Wilson MILLER, Wilson Guo, Qianyu MILLER, Wilson DUPÉRÉ-RICHER, Daphné Guo, Qianyu MILLER, Wilson MILLER, Wilson Kaddour, Nancy Guo, Qianyu MILLER, Wilson MILLER, Wilson FRIEDMANN, Jennifer Elisabeth MILLER, Wilson MILLER, Wilson DUPÉRÉ-RICHER, Daphné DAHABIEH, Michael MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MONETTE, Johanne MONETTE, Johanne WRIGHT, Kathryn MORAIS, José Antonio WRIGHT, Kathryn MORAIS, José Antonio MORAIS, José Antonio MORAIS, José Antonio Seltzer, Sean Rao, Shringar Rao, Shringar Alpuche Lazcano, Sergio Paulo MOULAND, Andrew MOULAND, Andrew MOULAND, Andrew MOULAND, Andrew MOULAND, Andrew MOULAND, Andrew MOULAND, Andrew Université McGill Role of eIF4E in promoting melanoma cell proliferation and maintaining acquired resistance to Vemurafenib in melanoma. Université McGill Effect of EiF4E knockdown on EMT. Université McGill Mechanisms of drug resistance in melanoma and lymphoma cells. Société canadienne du Cancer Role of eIF4E in promoting melanoma cell proliferation and maintaining acquired resistance to Vemurafenib in melanoma. Université McGill Elucidate the mechanism of the increased anti-leukemic potency of darinaparsin compared to arsenic trioxide. Fondation Cole Anti-cancer activity of HDAC inhibitors. Université McGill Elucidate the mechanism of the increased anti-leukemic potency of darinaparsin compared to arsenic trioxide. Université McGill Effect of EiF4E knockdown on EMT. Fondation Cole Elucidate the mechanism of the increased anti-leukemic potency of darinaparsin compared to arsenic trioxide. Université McGill McGill James Université McGill Sophisticated new approaches in immuno-therapy and novel targeted therapy in melanoma. Fondation Cole Anti-cancer activity of HDAC inhibitors. Fonds de la recherche en santé du mécanismes de résistance aux médicaments dans les hémopathies Québec (FRSQ) malignes Samuel Waxman Cancer Research Development of novel anti-cancer therapies using arsenic trioxide. Foundation Université McGill McGill James Université McGill Bridge Funding. Société canadienne du Cancer Functional role of elF4E in breast tumor metastasis and epithelial-tomesenchymal transition (EMT). Instituts de recherche en santé du Molecular mechanisms of retinoids as anti-virals in respiratory virus Canada (IRSC) infections Samuel Waxman Cancer Research Development of novel anti-cancer therapies using arsenic trioxide. Foundation Instituts de recherche en santé du Targeting the eukaryotic translation factor elF4E with ribavirin in breast Canada (IRSC) cancer. Université McGill Rossy Cancer Network (RCN). Instituts de recherche en santé du Mechanisms of response and resistance in epigenetic therapy in Canada (IRSC) hematological malignancy. Regroupement de particuliers 8th International Conference of differentiation therapy - Montreal October 3-6,1999. Instituts de recherche en santé du The CIHR/FRSQ Training Program in Cancer Research at McGill Canada (IRSC) Instituts de recherche en santé du RADAR : A new screening tool to improve the recognition of delirium Canada (IRSC) among elder persons Fonds de la recherche en santé du Utilisation des services médicaux d'urgence et hospitaliers chez la Québec (FRSQ) clientèle âgée de 75 ans et plus : Quel est l'impact de l'accès aux ressources médicales et communautaires de première ligne ? Fonds de la recherche en santé du L'impact de l'exercice et de la supplémentation en leucine sur le muscle Québec (FRSQ) squelettique de femmes âgées fragillisées avec une exploration des mécanismes justificatifs Fonds de la recherche en santé du L'impact de l'exercice et de la supplémentation en leucine sur le muscle Québec (FRSQ) squelettique de femmes âgées fragillisées avec une exploration des mécanismes justificatifs Instituts de recherche en santé du Veillissement et les maladies chroniques de RUIS McGill (Réseau Canada (IRSC) Universitaire Intégré de Santé McGill). Montreal General Hospital Helen McCall Hutchison award in geriatric medicine Foundation (Can) Université McGill Why HIV-1 dismantles NPCs? Université McGill Studies on HIV-1 cure. Université McGill Studies on HIV-1 cure. Consejo Nacional de Ciencia y Mechanisms of RNA interference and RNA Decay in cytoplasmic Tecnologia (CONACYT) (Mexico) granules during HIV-1 replication in monocytes. Instituts de recherche en santé du The Canadian HIV Cure Enterprise (CanCURE) Canada (IRSC) Instituts de recherche en santé du Understanding how the HIV-1-dependent ribonucleoprotein counters Canada (IRSC) host stress responses Instituts de recherche en santé du Evading and subverting host cell machineries to ensure HIV-1 genomic Canada (IRSC) RNA fate. 1,000 1,241 1,978 2,000 2,967 5,440 5,724 6,989 8,657 9,203 15,055 16,560 16,703 10,903 15,000 20,000 24,378 34,525 40,498 70,880 96,099 145,977 162,000 162,500 1,500 1,598 835 1,165 284 495 1,269 4,368 6,698 9,970 63,627 134,164 158,294 10 Borrelli, Daniel Sharif-Askari, Bahram PANASCI, Lawrence PANASCI, Lawrence PANASCI, Lawrence PANASCI, Lawrence PANASCI, Lawrence PANTOPOULOS, Kostas PANTOPOULOS, Kostas PANTOPOULOS, Kostas PANTOPOULOS, Kostas CHO, Chulmin PAUDEL, Hemant CHO, Chulmin PAUDEL, Hemant Jinhai, Duan PAUDEL, Hemant PAUDEL, Hemant PAUDEL, Hemant Yancu, Debbie Laaribi, Haithem Ruiz-Rosado, Azucena POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael POLLAK, Michael Zidova, Zuzana PONKA, Prem PONKA, Prem PONKA, Prem Jacob, Arthur RICHARD, Stéphane DARBELLI, Lama SONG, Jingwen RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane LI, Naomi RICHARD, Stéphane Université McGill Université McGill Regroupement de particuliers Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG) Instituts de recherche en santé du Canada (IRSC) Institut de recherche de la Société canadienne du Cancer (IRSCC) Université McGill Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG) Instituts de recherche en santé du Canada (IRSC) Société Alzheimer du Canada BKM120 in combination with chemotherapeutic drugs in CLL therapy. New formation of drugs encapsulated into DNA cage delivery system. Donations. DNA cages as a platform for efficient and selective delivery of therapeutics into tumour cells. DNA cages as a platform for efficient and selective delivery of therapeutics into tumour cells. Targeting cancer by small molecule inhibitors of iron regulatory protein 2 (IRP2). Iron and metabolism research. Iron metabolism and hepatitis C virus. Iron regulatory proteins: pathophysiological functions in metabolism and cancer. Developmentally regulated brain protein in Alzheimer's disease: Its role in synaptic dysfunction. Société Alzheimer du Canada Developmentally regulated brain protein in Alzheimer's disease: Its role in synaptic dysfunction. Guangdong Province Science and Examine the development of Alzheimer neuropathology in mouse Technology Foundation model. Société Alzheimer du Canada Restoration of synapse loss in AD by replenishment of drebrin in the CNS. Instituts de recherche en santé du Neurofibrillary pathology and amyloidogenesis in Alzheimer's disease: Canada (IRSC) mechanistic insights. Université McGill A study on metformin and its implications in cancer treatment. Université McGill Effect of LDH-A inhibition with metformin treatment in cancer. Consejo Nacional de Ciencia y Dose dependent effect of metformin in 4T1 mammary carcinoma growth Tecnologia (CONACYT) (Mexico) and phosphoprotein expression. Société de recherche sur le Development of an instrument for assessing occupational exposures in canacer Inc cancer case-control studies and its implication to cancers of lung, brain, ovary and colon. Société de recherche sur le Development of an instrument for assessing occupational exposures in canacer Inc cancer case-control studies and its implication to cancers of lung, brain, ovary and colon. Institut de recherche de la Société Defining the roles of systemic and direct tumour effects of biguanides to canadienne du Cancer (IRSCC) optimize treatment. Instituts de recherche en santé du Defining and Applying "Oncometabolism": A team approach in Canada (IRSC) understanding and translating the Warburg effect from oncogenic and tumour suppressing activities. National Institutes of Health (NIH) An investigation of circulating adiponectin levels and monoclonal (USA) gammopathy of undetermined significance (MGUS). Institut de recherche Terry Fox Unraveling metabolic adaptations associated with disease progression (IRTF) and therapeutic reponse in metastatic breast cancer Regroupement de particuliers IGF and breast cancer. Regroupement de particuliers Stroll - cancer screening. National Institutes of Health (NIH) A pooled investigation of circulating adiponectin levels and risk of (USA) multiple myeloma. National Institutes of Health (NIH) Nurses' health study I and II women's lifestyle validation study. (USA) European Union (EU) Research Investigation of the Role of Heme-Oxigenase I in the Erythroid Directorate General Differentation Instituts de recherche en santé du Chelation, mobilization and metabolism of storage iron. Canada (IRSC) Instituts de recherche en santé du Regulation of iron metabolism and heme synthesis in erythroid cells. Canada (IRSC) Université McGill The role of monomethylarginene and symmetric dimethylarginine gererated by PRMT5 and PRMT7 during the DNA damage signalling. Université McGill To identify alternatively spliced RNA targets of QKI in glial cells. Université McGill James McGill Professorship Award. Université McGill Does the Sam68 STAR RNA binding protein reuglate mTOR alternative splicing and mTOR signaling pathway? What are the roles of Sam68 in neu-oncogene-breast cancer development. Université McGill To define the role of Sam68 in p53-mediated functions. 2,000 4,945 28,000 33,334 66,667 16,209 17,500 36,000 148,200 5,200 15,830 24,740 18,544 130,276 956 3,225 6,384 5,087 7,737 10,014 16,773 23,566 25,405 35,545 39,711 69,801 161,040 33,045 117,763 133,831 652 1,058 1,648 1,893 2,115 11 Blanc, Roméo NEAULT, Mathieu RICHARD, Stéphane RICHARD, Stéphane LI, Naomi Blanc, Roméo BUENO, Murilo RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane NEAULT, Mathieu RICHARD, Stéphane RICHARD, Stéphane De Bruin, Ruben RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARD, Stéphane RICHARDS, Brent RICHARDS, Brent RICHARDS, Brent MANOUSAKI, Despoina RICHARDS, Brent RICHARDS, Brent RICHARDS, Brent RICHARDS, Brent RICHARDS, Brent RICHARDS, Brent Blank, Nimrod RUDSKI, Lawrence Blank, Nimrod RUDSKI, Lawrence Ouerd, Sofiane SCHIFFRIN, Ernesto MIAN, Muhammad Oneeb Rehman SCHIFFRIN, Ernesto IDRIS KHODJA, Noureddine SCHIFFRIN, Ernesto Trindade, Michelle SCHIFFRIN, Ernesto Al Nashmi, Tofol SCHIFFRIN, Ernesto Ouerd, Sofiane SCHIFFRIN, Ernesto Université McGill Fonds de la recherche en santé du Québec (FRSQ) Université McGill Université McGill Fonds de la recherche en santé du Québec (FRSQ) Université McGill Fonds de la recherche en santé du Québec (FRSQ) UNIVERSITAIR MEDISCH CENTRUM (UTRECHT) Université McGill Université McGill Société canadienne du Cancer The role of PRMTs in stem cell differentiation. Étude de la régulation de la signalisation du dommage à l'ADN par la méthylation d'arginine et les microARNs dans les cellules cancéreuses. To define the role of Sam68 in p53-mediated functions. The role of PRMTs in stem cell differentiation. L'évaluation du rôle de la Jumonji demethylase KDM2A au cours de la réponse aux dommages de l'ADN James McGill Professorship Award. Étude de la régulation de la signalisation du dommage à l'ADN par la méthylation d'arginine et les microARNs dans les cellules cancéreuses. The role of he RNA-binding protein quaking in inflammation. James McGill Professorship Award. James McGill Professorship Award. Defining the regulation of platelet-derived growth factor (PDGF) signaling by protein arginine methylation. Société canadienne du Cancer Defining the regulation of platelet-derived growth factor (PDGF) signaling by protein arginine methylation. Société Canadienne de la sclérose The role of quaking proteins in oligodendrocyte physiology and en plaques myelation. Instituts de recherche en santé du The role of the Sam68 RNA binding protein in normal and diseased Canada (IRSC) cells. Instituts de recherche en santé du The role of post-translational modifications of MRE11 in mediating the Canada (IRSC) DNA damage response. Instituts de recherche en santé du Defining the role of protein arginine methyltransferases (PRMTs) and Canada (IRSC) RGG/RG motifs in cancer in the maintenance of genomic stability. Fonds de la recherche en santé du Des causes à la clinique : Comprendre les déterminants génétiques de Québec (FRSQ) la maladie commune et, ainsi, permettre l'amélioration des soins aux patients 2014 Dr. Jody Ginsberg Young Investigator Award Société canadienne d'endocrinologie et métabolisme (SCEM) Fonds de la recherche en santé du Des causes à la clinique : Comprendre les déterminants génétiques de Québec (FRSQ) la maladie commune et, ainsi, permettre l'amélioration des soins aux patients Groupe canadien d'endocrinologie The role of rare and low-frequency genetic variation in vitamin D status. pédiatrique (GCEP) Université McGill Genetic determinants of 25-Hydroxy Vitmain D Levels Instituts de recherche en santé du Full resolution metabolic disease epigenomics in human populations Canada (IRSC) Université McGill Type 2 diabetes, glucose and coronary heart disease, a Mendelian randomization study. Instituts de recherche en santé du Full resolution metabolic disease epigenomics in human populations Canada (IRSC) Instituts de recherche en santé du Pinpointing causal variants for osteoporosis. Canada (IRSC) Israel Cancer Research Fund ICRF Fellowship. (ICFR) Israel Cancer Research Fund ICRF Fellowship. (ICFR) Université McGill Role of vascular smooth muscle cell PPAR-gamma in endothelin-1induced vascular disease. Réseaux de centres d'excellence Role of T regulatory lymphocytes in adlosterone-induced hypertension du Canada (RCE) Société Québécoise d’hypertension Oxidative stress mechanisms in vasculature of atherosclerotic type 1 artérielle diabetic mice. Foundation for the Coordination of Hypertension in Vascular Biology Higher Education and Graduate Training (CAPES Foundation) (Brazil) Saudi Arabian Cultural Bureau in Gene expression profile in small resistance arteries in patients with Canada hypertension with and without nephroangiolsclerosis and its relation to small and large artery function remodeling. Instituts de recherche en santé du Role of vascular smooth muscle cell PPAR-gamma in endothelin-1Canada (IRSC) induced vascular disease. 2,724 4,945 6,989 6,989 7,500 8,352 15,055 365,118 2,473 12,527 25,055 34,945 95,000 111,600 174,669 193,592 8,334 20,000 26,065 60,000 1,500 8,330 14,128 41,633 172,964 12,363 37,637 1,692 2,904 6,181 10,322 10,484 13,173 12 BARHOUMI, Tlili BARHOUMI, Tlili IDRIS KHODJA, Noureddine SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto COELHO, Suellen Cristina SCHIFFRIN, Ernesto Fraulob Aquino, Julio Cesar SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIFFRIN, Ernesto SCHIPPER, Hyman Morris SCHIPPER, Hyman Morris SCHIPPER, Hyman Morris SMALL, David SMALL, David SMALL, David Khosrow-Khavar, Farzin SUISSA, Samy SUISSA, Samy SUISSA, Samy Khosrow-Khavar, Farzin SUISSA, Samy Tascilar, Koray SUISSA, Samy SUISSA, Samy SUISSA, Samy WU, Jennifer SUISSA, Samy Faillie, Jean-Luc SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy SUISSA, Samy Université McGill Université McGill Fonds de la recherche en santé du Québec (FRSQ) Chaires de recherche du Canada (CRC) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) (Brazil) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) (Brazil) Chaires de recherche du Canada (CRC) Chaires de recherche du Canada (CRC) Regroupement de particuliers Juvenile Diabetes Research Foundation International Regroupement de particuliers Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) National Institutes of Health (NIH) (USA) Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Instituts de recherche en santé du Canada (IRSC) Regroupement de particuliers Regroupement de particuliers Regroupement de compagnies, corporations Université McGill Université McGill Fonds de la recherche en santé du Québec (FRSQ) Sir Mortimer B. Davis - Hôpital Général Juif Université McGill Université McGill Gouvernement de la Turquie Instituts de recherche en santé du Canada (IRSC) Université McGill Université McGill Société francophone du diabète (SFD) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Université McGill Université McGill Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Pathophysiology of hypertension. Pathophysiology of hypertension. L'endothéline-1, les isoformes de NOX et le stress oxydant dans l'athérosclérose associée au diabète de type 1 Hypertension and vascular research. 15,659 21,841 22,582 Endothelin, vascular inflammation and injury, and hypertension. 25,051 Vascular remodeling in hypertension. 38,108 Hypertension and vascular research. 75,171 Hypertension and vascular research. 100,137 24,658 Rodent phenotyping facility. Nox-derived Rox: Renal and vascular complications of type 1 diabetes. 781 14,754 Cardiohhypertension research "Fonds d'urgence". MicroRNAs and gene regulation on vascular remodeling in hypertension from mice to humans. T-regulatory cells and vascular injury in hypertension 40,000 123,293 142,230 Endothelin, vascular inflammation and injury, and hypertension. 149,170 Clinical assessment of patients with AD and NEC individuals. 89,774 Mary Katz Claman Foundation Funds. 146,018 Role of HO-1 in aging & Parkinsonian neural tissues III. 150,784 Pulmonory Oncology Staff. Airway center. Pulmonary Research. 3,000 15,000 26,400 James McGill Professor. James McGIll Professor. The use of stains and prevention of colorectal cancer-specific mortality. 797 797 1,566 The use of stains and prevention of colorectal cancer-specific mortality. 5,000 James McGill Professor. James McGIll Professor. Cardiovascular risk prediction for primary prevention in patients with rheumatoid arthritis. The use of insulin glargine and risk of colorectal cancer in patients with type 2 diabetes. James McGill Professor. James McGIll Professor. Pharmacoépidémiologie et pharmacologie sociale des médicaments du diabète de type 2. CIHR - Quebec Respiratory Health Training Program 9,203 9,203 15,000 Prince Edward Island Canadian Network for observational drug effect studies (CNODES) demonstration project. James McGill Professor. James McGIll Professor. Propensity scores and marginal structural models in drug safety research Newfoundland and Labrador CNODES demonstration project. Canadian Network for Observational Drug Effect Studies. 35,000 1,195 1,195 2,805 8,125 8,505 13,805 13,805 28,150 116,465 3,180,100 13 TAGALAKIS, Vicky Instituts de recherche en santé du Canada (IRSC) TAGALAKIS, Vicky Fondation des Maladies du Coeur du Québec TAGALAKIS, Vicky Instituts de recherche en santé du Canada (IRSC) THERRIEN, Judith Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Université McGill Rare Disease Foundation (The) JEWETT, Lisa THOMBS, Brett KWAKKENBOS, Linda THOMBS, Brett JEWETT, Lisa THOMBS, Brett THOMBS, Brett LEVIS, Alexander THOMBS, Brett Instituts de recherche en santé du Canada (IRSC) JEWETT, Lisa THOMBS, Brett DELISLE, Vanessa THOMBS, Brett JEWETT, Lisa THOMBS, Brett MILETTE, Katherine THOMBS, Brett Rheumatology Research Foundation Rheumatology Research Foundation Conseil de Recherches en Sciences Naturelles et Génie du Canada (CRSNG) Instituts de recherche en santé du Canada (IRSC) RAZYKOV, Ilya THOMBS, Brett THOMBS, Brett KWAKKENBOS, Linda THOMBS, Brett THOMBS, Brett JEWETT, Lisa THOMBS, Brett THOMBS, Brett New oral anticoagulants for the prevention of venous thromboembolism in high-risk ambulatory cancer patients: A randomized placebocontrolled, double-blind clinical trial. Screening for occult malignancy in patients with unprovoked venous thromboembolism: a randomized controlled trial using a comprehensive computed tomography of the abdomen/pelvis (SOME trial). 1,200 The use of extended peri-operative low molecular weight heparin to improve cancer specific survival following surgical resection of colon cancer: A randomized controlled trial - PERIOP-01. The Canadian outcomes registry late after TEtralogy of fallot repair (CORRELATE). Une intervention visant à réduire la détresse reliée à l'image corporelle chez les femmes avec défigurement causé par la sclérodermie Scleroderma patient-centered interventions network (SPIN). 12,884 5,500 Social anxiety from disfigurement due to medical illness: From assessment to intervention. 5,987 Cancer de la prostate Canada THOMBS, Brett THOMBS, Brett MCGEE, Shauna Mokhtar, Shaza TRIFIRO, Mark A TRIFIRO, Mark A MCGEE, Shauna TRIFIRO, Mark A TRIFIRO, Mark A 254 Health Professional Research Preceptorship. TRIFIRO, Mark A THOMBS, Brett 36 5,500 TRIFIRO, Mark A THOMBS, Brett THOMBS, Brett 1,000 William Dawson Scholar Testing the feasibility of the changing faces practitioner training and induction program for scleroderma patients. Assessing excess significance bias in randomized controlled trials of non-pharmacological interventions for pain management in rheumatic diseases. Health Professional Research Preceptorship. Barriers to depression screening in medical setting: Examining cumulative false-positive rates and possible solutions in rheumatology, oncology, and cardiovascular care settings. Université McGill William Dawson Scholar Instituts de recherche en santé du Understanding suicidal thinking and risk in a chronic, progressive Canada (IRSC) disease: From epidemiology to application. Société de l'arthrite (La) The Scleroderma patient-centred intervention Network (SPIN). Fonds de la recherche en santé du La fatigue lié aux maladies chroniques dans la sclérodermie: de Québec (FRSQ) l'évaluation à l'intervention Société de l'arthrite (La) The Scleroderma patient-centred intervention Network (SPIN). Instituts de recherche en santé du Social anxiety from disfigurement due to medical illness: From Canada (IRSC) assessment to intervention. Université McGill William Dawson Scholar Searching for identity in the dark: The experiences of women living in Conseil de Recherches en rare and unpredictable disease. Sciences Humaines du Canada (CRSH) Université McGill William Dawson Scholar Regroupement de particuliers International Consortium for Bevavorial/Educational/Psychological Interventions for Scleroderma. - SPIN COHORT NETWORK. Instituts de recherche en santé du The Scleroderma patient-centered intervention network (SPIN) Canada (IRSC) feasibility trial planning meeting. Research Foundation Sir Mortimer International Consortium for Bevavorial/Educational/Psychological B. Davis, Jewish General Hospital Interventions for Scleroderma. - SPIN COHORT NETWORK. Instituts de recherche en santé du Emerging Team: The Scleroderma patient-centered intervention Canada (IRSC) Network. Université McGill Dissecting and modeling networks for cancer cell survival. Saudi Arabian Cultural Bureau in Understanding the molecular pathology of spinal and bulbar muscular Canada atrophy by identifying genetic interactors of an AR-Humanized fly. Instituts de recherche en santé du Approche de la biologie des systèmes à l'hétérogénéité tumorale dans Canada (IRSC) le cancer de la prostate Cancer de la prostate Canada Novel targeting abiotic therapeutics and imaging agents for prostate cancer. Cancer de la prostate Canada Androgen receptor-mediated translational regulation in prostate cancer. THOMBS, Brett THOMBS, Brett 4,945 Novel targeting abiotic therapeutics and imaging agents for prostate cancer. 1,195 3,221 5,000 12,355 13,805 14,615 21,635 30,000 65,865 70,000 797 6,234 9,203 14,325 14,629 50,000 299,958 1,692 8,736 17,500 14,830 21,548 44,995 14 KHANASSOV, Vladimir TRIFIRO, Mark A TRIFIRO, Mark A TRIFIRO, Mark A Jewish Hospital Foundation Jewish Hospital Foundation Cancer de la prostate Canada Artificial pancreas research project. Insulin pump center. Androgen receptor-mediated translational regulation in prostate cancer. 50,000 75,791 79,139 TRIFIRO, Mark A Instituts de recherche en santé du Canada (IRSC) Regroupement de particuliers Fonds de la recherche en santé du Québec (FRSQ) Innovative approaches to functional characterization of the androgen receptor in prostate cancer. Endocrinology research and development. Gestion de cas pour les patients avec des troubles cognitifs en soins de santé primaires et communautaires: obstacles à l'implantation. Revues systématiques mixtes de la littérature Maladie d'Alzheimer et multimorbidité : adapter et améliorer la qualité et l'efficacité des services de première ligne Maladie d'Alzheimer: adapter et améliorer la qualité et l'efficacité des services de première ligne Veillissement et les maladies chroniques de RUIS McGill (Réseau Universitaire Intégré de Santé McGill). Déterminants de la continuité des soins aux personnes âgées vulnérables inscrites auprès d'un médecin d'une unité de médecine familiale du Québec : une étude transversale. Maladie d'Alzheimer et multimorbidité : adapter et améliorer la qualité et l'efficacité des services de première ligne Maladie d'Alzheimer et multimorbidité : adapter et améliorer la qualité et l'efficacité des services de première ligne Assessing care models implemented in primary health care for persons with Alzheimer's disease and related disorders Start-Up Funds - Epidemiology 102,692 TRIFIRO, Mark A VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle VEDEL, Isabelle Liang, Jia Ming (Calvin) King, Stacey Cutillas, Vincent WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. King, Stacey QUASHIE, Peter WAINBERG, Mark A. WAINBERG, Mark A. ANSTETT, Kaitlin SINGHROY, Diane Zanichelli, Veronica ANSTETT, Kaitlin WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. DEPATUREAUX, Agnes WAINBERG, Mark A. HASSOUNAH, Said WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. Fonds de la recherche en santé du Québec (FRSQ) Instituts de recherche en santé du Canada (IRSC) Instituts de recherche en santé du Canada (IRSC) Fonds de la recherche en santé du Québec (FRSQ) Fonds de la recherche en santé du Québec (FRSQ) Fonds de la recherche en santé du Québec (FRSQ) Instituts de recherche en santé du Canada (IRSC) Research Foundation Sir Mortimer B. Davis, Jewish General Hospital Fonds de recherche du Québec - Plan d'action ministériel sur les troubles cognitifs liés au vieillissement: Santé (FRQS) une évaluation de l'implantation et des résultats des projets initiaux en vue d'une généralisation progressive au Québec. Research Foundation Sir Mortimer Start-Up Funds - Epidemiology B. Davis, Jewish General Hospital Université McGill Effect of integrasi inhibitor, dolutegraivre, on the molecular evolution. University of Liverpool (The) (UK) Selection of HIV drug resistance against novel compounds. Université McGill James McGill Professor. Instituts de recherche en santé du The addition of R262K to the H51Y mutation in HIV-1 subtype B Canada (IRSC) integrase confers low-level resistance against dolulegravir. University of Liverpool (The) (UK) Selection of HIV drug resistance against novel compounds. Instituts de recherche en santé du Drug resistance of HIV to second generation integrase inhibitors. Canada (IRSC) Université McGill Investigating resistance phenotypes in HIV-1. Université McGill The contribution of cellular PRMT6 to HIV-1 pathogenesis. University of Padova Studies on HIV drug resistance involving integrase inhibitors. Instituts de recherche en santé du Investigating resistance phenotypes in HIV-1. Canada (IRSC) Réseau Canadien pour les Essais HIV-1 group O integrase: Impact of genetic polymorphisms on integrase VIH (Vancouver, B.C.) inhibitors resistance (IIs) and on enzymatic activity. Université McGill James McGill Professor. Fonds de la recherche en santé du Validation de SIVmac239 comme un modèle primate non humain pour Québec (FRSQ) l'étude de la résistance du VIH aux inhibiteurs d'intégrase Université McGill James McGill Professor. Université McGill James McGill Professor. National Institutes of Health (NIH) HIV Prevention Trial Network Leadership: Biomedical Sciences (USA) Committee Chair Canadian Foundation for AIDS Investigating the role of subtype-specific polymorphisms in HIV-1 Research (CANFAR) resistance to integrase inhibitors. Regroupement de compagnies, Québec Conference. fondations et particuliers (Canada) Fonds de la recherche en santé du SIDAMI-Surveillance de l'épidémie de résistance du VIH. Québec (FRSQ) Fonds de la recherche en santé du Réseau SIDA et maladies infectieuses coordination Québec (FRSQ) Fonds de la recherche en santé du SIDAMI-Banque de spécimens viraux/Traitement des échantillons Québec (FRSQ) 136,683 3,125 9,452 45,000 569 800 2,473 7,527 45,499 50,000 77,546 130,000 582 1,033 1,195 1,500 1,997 2,500 2,750 5,011 5,885 10,192 13,599 13,805 16,703 797 9,203 9,667 19,780 22,292 30,000 31,250 40,000 15 WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WAINBERG, Mark A. WARSHAWSKY, Paul BALLARD, Stephanie WILCHESKY, Machelle WILCHESKY, Machelle WILCHESKY, Machelle Melnychuk, Luca ZAHARATOS, Gerasimos Industrial Contracts AGULNIK, Jason Fonds de la recherche en santé du Québec (FRSQ) Instituts de recherche en santé du Canada (IRSC) Laboratoire de santé publique du Québec SIDAMI-Génotypage de la résistance au VIH. 47,000 What if HIV were unable to develop resistance against a new therapeutic agent? Phase 2 - Infrastructures pour la recherche sur l'infection au IVH: doter le Québec et le Canada d'infrastructures pour un vaccin et des thérapies contre le VIH et l'hépatite. Genetic signatures and functional phenotypes implicated in HIV-1 transmission and drug resistance. Viral and human genetic predictors of response to HIV therapies. TanZamBo capacity building for HIV prevention research network. 61,424 Instituts de recherche en santé du Canada (IRSC) Genome British Columbia Centre de Recherches pour le Développement International (CRDI) Regroupement de compagnies, AIDS Research. fondations et particuliers (Canada) Instituts de recherche en santé du The Botswana-Canada AIDS vaccine discovery partnership. Canada (IRSC) Université McGill Developing and testing innovative implementation strategies of and integrated systematic pain assessment approach in the adult intensive care unit Centre Gériatrique Maimonides Validation of the elder abuse suspicion index (EASI) in the geriatric longDonald Berman (Le) term care setting. Fonds de la recherche en santé du Non-pharmacological management of behavioral and psychological Québec (FRSQ) symptoms of dementia (BPSD) in long-term care: social determinants of adherence to clinical guidelines Instituts de recherche en santé du Prevention and Treatment of Neuropsychiatric Symptoms - Canadian Canada (IRSC) Consortium on Neurodegeneration in Aging (CCNA Team 11) Instituts de recherche en santé du Highly stable trimerization of HIV-1 envelope based antigens will Canada (IRSC) improve their immunogenicity and capacity to elicit a neutralizing antibody responses. AGULNIK, Jason Hoffmann-La Roche Limitée, Canada Morphotek Inc AGULNIK, Jason Glaxo Wellcome Inc. ASSOULINE, Sarit Proteolix ASSOULINE, Sarit ARIAD Pharmaceuticals Inc. ASSOULINE, Sarit Glaxo Smith Kline ASSOULINE, Sarit Bristol-Myers Squibb Canada Inc. ASSOULINE, Sarit Glaxo Smith Kline ASSOULINE, Sarit Onyx Pharmaceuticals ASSOULINE, Sarit Bristol-Myers Squibb Canada Inc.Novartis Pharma Canada Inc. ASSOULINE, Sarit Wyeth - Ayerst Canada Inc. (StLaurent, QC et North York, ON) Treatment of metastatic EGFR wild type non-small cell lung cancer with 2nd or 3rd line erlotinib. A retrospective practice view. A randomized double-blind, placebo-controlled, study of the safety and efficacy of Farletuzumab in combination with a platinum containing doublet in chemotherapy-naïve subjects with stage IV adenocarcinoma of the lung. A double-blind, randomized, placebo-controlled phase III study to assess the efficacy of recMAGE-A3-A3+ antigen-specific cancer immunotherapeutic as adjuvant therapy in patients with MAGE-A3positive non-small cell lung cancer. CRU - An open-label, single-arm, phase 2 study of carfilzomib maintenance therapy in subjects previously enrolled in carfilzomib treatment protocols. CRU - A pivotal phase 2 trial of Ponatinib (AP24534) in patients with refractory chronic myeloid leukemia and ph+ acute lympnobastic leukemia. CRU - A three-part study of Eltrombopag in thrombocytopenic subjects with myelodysplastic syndromes or acute myeloid leukemia (part 1: open label, part 2: randomized, double-blind, part 3: extension. CRU-A single-arm, open-label phase 2 study of Nivolumab (BMS936558) in subjects with relapsed or refractory follicular lymphoma (FL). An extension study of eltrombopag olamine (SB-497115-GR) in adults, with idiopathic thrombocytopenic purpura (ITP), previously enrolled in an eltrombopag study. CRU-An open-label single arm, phase I study of the pharmacokinetics and safety of carfilzomib in subjects with relapsed multiple myeloma and end-stage renal disease. (Q-CROC-02) - A randomized phase II study of oral panobinostat (LBH1589) with or without rituximab (the "Study Drug") to treat relapsed or refractory B-cell non-Hodgkin lymphoma. CRU - A phase 1/2 study of SKI-6-6 in Philadelphia chromosome positive leukemias. 61,939 103,442 126,844 168,909 462,400 489,988 5,625 10,192 2,000 10,116 7,308 4,980 9,294 14,030 118 4,040 4,310 7,500 7,611 8,333 10,023 10,072 16 ASSOULINE, Sarit Pharmacyclics ASSOULINE, Sarit Novartis Pharmaceuticals Corporation ASSOULINE, Sarit Millennium Pharmaceuticals Inc (Cambridge, MA, USA) ASSOULINE, Sarit Infinity Pharmaceuticals ASSOULINE, Sarit Genzyme Corp. ASSOULINE, Sarit AbbVie ASSOULINE, Sarit Hoffmann-La Roche Limitée, Canada ASSOULINE, Sarit Onyx Industries Inc. ASSOULINE, Sarit Hoffmann-La Roche Limitée, Canada ASSOULINE, Sarit Quintiles Inc. (USA) ASSOULINE, Sarit Genentech Inc.. ASSOULINE, Sarit Hoffmann-La Roche Limitée, Canada ASSOULINE, Sarit Bristol-Myers Squibb Canada Inc. ASSOULINE, Sarit Gilead Sciences ASSOULINE, Sarit Medimmune Inc. ASSOULINE, Sarit Genentech Inc.. BARON, Murray JSS Recherche médicale BARON, Murray Abbott Laboratories BARON, Murray Hoffmann-La Roche Limitée, Canada BARON, Murray Mount Sinai Hospital BATIST, Gerald Sunshine Biopharma Inc CRU - A multicenter, open-label, phase 2, safety and efficacy study of the Bruton's tyrosine kinase (Btk) inhibitor, pCI-32765, in subjects with relapsed or refractory de Novo diffuse large B-cell lymphoma. CRU-A phase II multi-center, open, label, randomized study to assess safety and efficacy of two different schedules of oral LDE225 in adult patients with relapsed/refractory or untreated elderly patients with acute leukemia. CRU - An open-label, dose-escalation, phase 1 study of MLN9708, a second-generation proteasome inhibitor, in adult patients with lymphoma. CRU-A phase 2 study of IPI-145 in subjects with refractory indolent nonHodgkin lymphoma. CRU - A phase 3, randomized, double-blind, placebo-controlled, multicenter study confirming the efficacy and safety of Genz-112638 in patients with Gaucher Disease Type 1. CRU - A phase 2 open-label study of efficacy of ABT-199 in subjects with relapsed or refractory chronic lymphocytic leukemia harboring the 17p deletion. CRU-An adaptive,comparative,randomized,parallel-group,multicenter,phase lb study of subcutaneous (SD) rituximab versus intravenous rituximab both in combination with chemotherapy (fludarabine and cyclophosphamide),in patients with previously untreated... CRU - A randomized, multicenter, phase 3 studycomparing carfilzomib, lenalidomide, and dexamethasone (CRd) vs. lenalidomide and dexamethasone (Rd) in subjects with relapsed multiple myeloma. CRU-GO28852-A phase IB/II study, to evaluate the safety and efficacy of vismodegib in relapsed/refractory acute myelogenous leukemia (AML) and relapsed/refractory high-risk myeloldysplastic syndrome (MDS). CRU-A multicenter, phase III, open-label, randomized study in relapsed/refractory patients with chronic lymphocytic leukemia to evaluate the benefit of GDC-0199 (ABT-199) plus rituximab compared with bendamustine plus rituximab. CRU - A randomized, open-label, multicenter, phase II trial evaluating the safety and activity of DCDT2980S in combination with rituximab or DCDS4501A in combination with rituximab in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma. CRU - A multi center, open-label, phase 1/1b study of escalating doses of RO5503781 administered orally as a single agent or in combination with cytarabine in patients with acute myelogenous leukemia (AML) CRU-A single-arm, open-label, phase 2 study of Nivolumab (BMS936558) in subjects with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) after failure of autologous stem cell transplant (ASCT) or after failure of at least two prior multi-agent CRU-A Phase 2 open-label study evaluating the efficacy, safety, tolerability, and pharmacodynamics of GS9973 in subjects with relapsed or refractory hematologic malignancies. CRU-A phase 2 open-label study of MEDI-551 and Bendamustine vs Rituximab and Bendamustine in adults with relapsed or refractory CLL. CRU-An open-label, multicenter, randomized, phase III study to investigate the efficacy and safety of bendamustine compared with bendamustine + RO5072759 (GA101) in patients with rituximabrefractory, indolent non-hodgkin's lymphoma. A Canadian randomized controlled trial (RCT) of real world Cimzia treatment in RA: Randomizing to stop vs continued DMARDs. Real life evaluation of rheumatoid arthritis in Canadians taking HUMIRA. A Phase II/III, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of tocilizumab versus placebo in patients with systematic sclerosis. The Canadian ArTHritis CoHort (CATCH): A prospective cohort study of adults with new-onset inflammatory arthritis symptoms. A biomarker-driven therapy in the age of personalized cancer medicine. 10,921 11,542 13,128 13,578 14,888 21,060 21,240 27,809 29,300 29,567 37,301 39,700 44,085 104,014 141,690 273,459 323 1,800 15,583 19,625 0 17 BATIST, Gerald BLOSTEIN, Mark BLOSTEIN, Mark BLOSTEIN, Mark CHERTKOW, Howard CHERTKOW, Howard CHERTKOW, Howard COHEN, Albert COHEN, Albert COHEN, Albert COHEN, Albert COHEN, Victor COHEN, Victor COHEN, Victor COHEN, Victor COHEN, Victor DASCAL, André EISENBERG, Mark FALLAVOLLITA, Sabrina FALLAVOLLITA, Sabrina AstraZeneca Canada Inc. CRU-A phase I, open-label, multicenter study to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumour activity of ascending doses of AZD5363 under adaptable dosing schedules in patients with advanced solid malignancies. Glaxo Smith Kline Treatment of thromBocytopenia with EltRombopag or intrevenous immune globulin (IVIG) before and DurING invasive procedures in patients with immune thrombocytoPenia - BRIDGING ITP study. Sanofi-Aventis (Canada) ENOXA_L_02260-VTE Registry - National, prospective, observational cohort study of venous thrombembolism management with the low molecular weight heparin, enoxaparin, in the outpatient setting in Canada. Boehringer Ingelheim (Canada) Ltd A phase III, case series clinical study of the reversal of the anticoagulant effects of dabigatran by intravenous administration of 5.0g idarucizumab (BI 655075) in patients treated with dabigatranetexilate who have uncontrolled bleeding Merck Frosst Canada Inc A randomized, placebo controlled, parallel-group, double-blind efficacy and safety trial of MK-8931 in subjects with mild to moderate Alzheimer's disease. Abbott Laboratories A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ABT-126 in subjects with mild-to-moderate Alzheimer's Disease on stable doses of acetychloniesterase inhibitors. TauRx Therapeutics Ltd. Randomized, double-blind, placebo-controlled, parallel-group, 18-month safety and efficacy study of leuco-methylthioninium bis(hydromethanesulfonate) in subjects with mild Alzeimer's disease. A 52 week randomised, double-blind, placebo-controlled study to Robarts Research Institute investigate the efficacy and safety of GSK1605786A in the maintenance (formerly John P. Robarts of remission in subjects with Crohn's disease. Research Institute) Abbott Laboratories M10-223 - A multicenter, open-label study of the human anti-TNF monoclonal antibody adalimumab to evaluate the long term safety and tolerability of repeated administration of adalimumab in subjects with ulcerative colitis. An open-label extension study to assess the safety of GSK1605786A in Robarts Research Institute subjects with Crohn's disease. (formerly John P. Robarts Research Institute) Quintiles Canada Inc. A phase 3, open-label study to determine the long-term safety and efficacy of MLN002 in patients with iulcerative colitis and Crohn's disease. Boehringer Ingelheim (Canada) Ltd An open label trial of afatinib in treatment-naive or chemotherapy pretreated patients with locally advanced or metastatic non-small cell lunch cancer (NSCLC) harboring EGFR mutation(s). Astellas Pharma Inc. A randomized, double-blind, phase 2 study of erlotinib (Tarceva) in combination with OSI-906 or placebo in chemonaive patients with advanced NSCLC with activating mutations of the epidermal growth factor receptor (EGFR) gene. Pharmaceutical Research A multi-center phase III randomized, double-blind placebo-controlled Associates Inc. study of the cancer vaccine Stimuvax (L-BLP25 or BLP25 liposome vaccine) in non-small cell lung cancer (NSCLC) subjects with unresectable stage III disease. Hoffmann-La Roche Limitée, Poplar: A phase II, open-label, multicenter, randomized study to Canada investigate the efficacy and safety of MPDL3280A (ANTI-PD-L1 ANTIBODY) compared with docetaxel in patients with non-small cell lung cancer after platinum failure. Hoffmann-La Roche Limitée, OAK-A phase III, open-label, multicenter, randomized study to Canada investigate the efficacy and safety of MPDL3280A (Anti-PD-L1 antibody) compared with docetaxel in patients with non-small cell lung cancer after failure with platinum-containing chemotherapy. Medpace Inc. A phase II, randomized, double-blind, active-controlled clinical study to investigate the efficacy and safety of SMT19969 (200mg BID) for 10 days comparted with vancomycin (125mg QID) for 10 days for the treament of Pfizer Canada Inc. GA3041Z4-Evaluation of Varenicline-(ChampixTM) in smoking cessation for patients post-acute coronary syndrome (EVITA) trial. JSS Recherche médicale Prospective observtional study to evaluate the use of musculoskeletal ultrasonography to improve rheumatoid arthritis management: Canadian experience (Echo Study). Abbott Laboratories Ltd Drug HUMIRA. 147,118 3,816 27,000 39,542 3,000 37,386 48,962 2,548 3,833 5,017 11,995 10,009 13,349 15,788 30,500 33,844 3,856 30,000 2,340 4,100 18 FERRARIO, Cristiano Celldex Therapeutics FERRARIO, Cristiano Bristol-Myers Squibb Canada Inc.Novartis Pharma Canada Inc. FERRARIO, Cristiano FERRARIO, Cristiano Hoffmann-La Roche Limitée, Canada Scimega Recherche GREENAWAY, Christina Sanofi Pasteur Inc. (USA) GYGER, Martin Celgene Corporation GYGER, Martin Celgene Corporation GYGER, Martin Celgene Corporation HILZENRAT, Nir HILZENRAT, Nir HILZENRAT, Nir HIRSCH, Andrew HIRSCH, Andrew HUDSON, Marie HUDSON, Marie KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca KAHN, Susan Rebecca A randomized multicenter pivotal study of CDX-011 (CRO11-vcMMAE) in patients with metastatic, GPNMB over-expressing, triple-negative breast cancer. A phase II randomized, double-blind placebo controlled, study of letrozole with or without BYL719 or buparlisib, for the neoadjuvant treatment of postmenopausal women with hormone receptor-positive HER2-negative breast cancer. CRU - A phase II, multicenter, single-arm study of MDPL3280A in patients with locally advanced or metastatic urothelial bladder cancer. CRU - A phase 1b, open-label study to assess the safety and tolerability of ONT-380 combined with ado-trastuzumab emtansine (T-DM1). 9,429 10,438 47,154 52,637 Efficacy, immunogenicity and safety study of clostridium difficile toxoid vaccine in subjects at risk for C. difficile infection. CRU-A phase 3, multicenter, randomized, open-label Study to Compare the Efficacy and Safety of Pomalidomide in Combination with Low-Dose Dexamethasone versus High-Dose Dexamethasone in Subjects with Refractory or Relapsed and Refractory Multiple Myeloma. 84,265 CRU-Companion Study: Open-Label, Multi-Center, Single-Arm Study for the Safety and Efficacy of Pomalidome (CC-4047) Monotherapy for Subjects with Refractory or Relapsed and refractory Multiple Myeloma. 4,389 CRU-A multicenter, single-arm, open-label treatment use program for pomalidomide (POM in combination with low dose dexamethasone (LdDex) in subjects with relapses or refractory multiple myeloma. Janssen Pharmaceutica Inc A Canadian retrospective registry to examine real world effectiveness, safety, patient characteristics, and healthcare management across various practice settings in HCV-infected patients who initiated treatment with simeprevir. Bristol-Myers Squibb Canada Inc. A phase 3 study with Asunaprevir and Declatasvir (DUAL) for null or partial responders to peginterferon alfa-2a and ribavirin (P/R), intolerant or ineligible to P/R subjects and treatment naive subjects with chronic hepatitis C genotype 1b infection. AbbVie An international multicenter prospective observational study to evaluate the epidemiology, humanistic and economic outcomes of treatment for chronic hepatitis C virus (HCV) MOSAIC. Bayer Canada Inc. Long-term extension, multi-centre, multi-national study to evaluate the safety and tolerability of oral BAY 63-2521 (1 mg, 1.5 mg, 2 mg, or 2.5 mg tid) in patients with chronic thromboembolic pulmonary arterial hypertension. Bayer Canada Inc. An open-label phase IIIb study of riociguat in patients with in-operable CTEPH, or recurrent or persisting pulmonary hypertension (PH) after surgical treatment who are not satisfactory treated and cannot participate in any other CTEPH trial. JSS Recherche médicale Prospective observational study to evaluate the use of musculoskeletal ultrasonography to improve rheumatoid arthritis management: Canadian experience (Echo Study). Janssen Pharmaceutica Inc Health-related quality of life (HRQol) across systematic autoimmune rheumatic diseases (SARD). Lawson Health Research Institute A prospective study of upper extremity deep vein thrombosis to determine the prevalence of post-thrombotic syndrome in patients managed with anticoagulation. Bayer (Canada) Inc. Reduced-dosed rivaroxaban and standard-dosed rivaroxaban versus ASA in the long-term prevention of recurrent symptomatic venous thromboemgolism (VTE) in patients with symptomatic deep-vein thrombosis and/or pulmonary embolism (Study 16416). Biomérieux Canada Inc. REVERSE-REcurrent VEnous thromboembolism risk stratification evaluation II: Validation of the "Men and HERD002" - A clinical decision rule to identify patients with "Unprovoked" venous thromboembolism who can discontinue anticoagulants after six months of Daiichi Pharmaceutical Corporation A randomized, open-label, parallel-group, multi-center study for the evaluation of efficacy & safety of edoxaban monotherapy versus (LMW) heparin/warfarin in subjects with symptomatic deep-vein thrombosis edoxaban thrombus reduction imaging study (eTRIS 3,304 15,842 1,500 8,105 8,535 2,604 8,561 2,918 17,361 1,250 5,750 6,000 12,199 19 KAHN, Susan Rebecca KARAPLIS, Andrew C. KARAPLIS, Andrew C. KARAPLIS, Andrew C. KAVAN, Petr Portola Pharmaceuticals, Inc. (USA) Multicenter, randomized, active-controlled efficacy and safety study comparing extended duration betrixaban with standard of care enoxaparin for the prevention of venous thromboembolism in acute medically III patients. Amgen Canada Inc (Mississauga, Prospective observational study to evaluate persistence with Prolia Ont) (denosumab) in postmenopausal women with osteoporosis in routine clinical practice. Eli Lilly Canada Inc. Teriparatide and risedronate in the treatment of patients with severe postmenopausal osteoporosis: Comparative effects on vertebral fractures. Amgen Canada Inc (Mississauga, A multi-center, international, randomized, double-blind, alendronateOnt) controlled study to determine the efficacy and safety of AMG785 in the treatment of postmenopausal women with osteoporosis. Amgen Canada Inc (Mississauga, A Phase 3, Randomized, Double-blind, Placebo-Controlled Study of Ont) Pegfilgrastim Administered to Subjects With Newly DX, LocallyAdvanced or Metastatic Colorectal Cancer Treated With Bevacizumab and Either 5-Fluorouracil, Oxaliplatin, Leucovorin (Folfox) or KAVAN, Petr Genentech Inc.. KAVAN, Petr Eisai Inc. (New Jersey) KAVAN, Petr Oncozyme Pharma Inc. KAVAN, Petr KAVAN, Petr KAVAN, Petr KAVAN, Petr KAVAN, Petr KAVAN, Petr KAVAN, Petr LANGLEBEN, David LANGLEBEN, David LANGLEBEN, David A Randomized, Double Blind, Placebo Controlled, Multicenter Phase II Study Evaluating the Efficacy and Safety of Onartuzuabm (MetMab) in Combination with Bevacizumab or Onartuzumab Monotherapy in Patients with Recurrent Glioblastoma A Multicenter, Randomized, Open-Label, Phase 3 Trial toCompare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-Line Treatment of Subjects With Unresectable Hepatocellular Carcinoma CRU - A phase II clinical study using Pentamidine in patients with metastatic cancer undergoing standard chemotherapy (mFOLFOX6 or FOLFIRI) as second-line treatment. Sanofi-Aventis (Canada) A Randomised Phase III Study of Capecitabine or 5-Fluorouracil-Based Regimen with or without Oxaliplatin as 2nd Line Treatment of Advanced or Metastatic Pancreatic Cancer in Patients Who Have received Gemcitabine-Based Chemotherapy Hoffmann-La Roche Limitée, A randomized, phase III, multicenter, double-blind, placebo-controlled Canada study evaluating the efficacy and safety of onartuzumab (metmab) in combination with 5-fluorouracil, folinic acid, and oxaliplatin (MFOLFOX6) in patients with metastatic HER2-negative, Bristol-Myers Squibb Canada CRU - A phase Ib/II multi-center, open-label, dose escalation study of Inc.Novartis Pharma Canada Inc. LGX818 and cetuximab or LGX818, BYL719, and cetuximab in patients with BRAF mutant metastatic colorectal cancer. Amgen Canada Inc (Mississauga, A retrospective observational study to estimate the attrition of patients Ont) across lines of systemic treatment for metastatic colorectal cancer in Canada. Boehringer Ingelheim (Canada) Ltd A double-blind, randomized, placebo controlled phase III study of nintedanib plus best supportive care (BSC) versus placebo plus BSC in patients with metastatic colorectal cancer refrectory to standard therapies Boehringer Ingelheim (Canada) Ltd BIBW 2992 WITH OR WITHOUT DAtLY TEMOZOLOMIDE IN THE TREATMENT OF PATIENTS WITH RECURRENT MALIGNANT GLIOMA Sanofi-Aventis (Canada) A Multicenter, Single arm, Open Label Clinical Trial to Evaluate the Safety and Health-Related Quality of Life of Aflibercept in Patients with Metastatic Colorectal Cancer (mCRC) Previously Treated with an Oxaliplatin-Containing Regimen, McG1308 Actelion Pharmaceuticals Canada A prospective, multicenter, double-blind, randomized, placeboInc. controlled, parallel-group, 12-week study to evaluate the safety and tolerability of macitentan in subjects with combined pre-and postcapillary pulmonary hypertention (CpcPH) due to left Bayer Canada Inc. An open-label phase IIIb study of riociguat in patients with in-operable CTEPH, or recurrent or persisting pulmonary hypertension (PH) after surgical treatment who are not satisfactory treated and cannot participate in any other CTEPH trial. Actelion Pharmaceuticals Canada AC-065A303: Long-term single-arm open-label study, to assess the Inc. safety and tolerability of Act-293987 in patients with pulmonary arterial hypertension. 45,484 3,546 10,172 24,218 191 549 1,097 1,891 1,964 2,848 3,127 3,260 4,089 6,005 17,040 5,800 9,218 9,802 20 LANGLEBEN, David LANGLEBEN, David LONGTIN, Yves MICHEL, Caroline MICHEL, Caroline MILLER, Mark A. MILLER, Mark A. MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson MILLER, Wilson Actelion Pharmaceuticals Canada Inc. A multicenter, double-blind placebo-controlled phase 3 study to demonstrate the efficacy and safety of ACT-293987 in patients with pulmonary arterial hypertension. Institut de Cardiologie de Montréal Phase-II study of the use of PulmoBind for molecular imaging of (ICM) pulmonary hypertension. Agence de santé publique du Vancomycin-resistant enterocci (VRE) occurrence report protocol Canada (ASPC) Canadian nonsocomial infection surveillance program (CNISP). Bayer Canada Inc. A randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the hemodynamic effects of riociguat (BAY 632521) as well as study & kinetics in patients with pulmonary hypertension associated with left ventricular... Aventis Pharma Heart failure clinic equipment donation. Merck Frosst Canada Inc A phase III, randomized, double-blind, placebo-controlled, adaptive design study of the efficacy, safety, and tolerability of a single infusion of MK-3415 (human monoclonal antibody to Clostridium difficile toxin A), Merck Frosst Canada Inc A phase III, double-blind, randomized, placebo-controlled, multicenter clinical trial to study the safety, tolerability, efficacy , and immunogenicity of V212 in recipients of autologous hematopoietic cell transplants (HCTs). MethylGene Inc. CRU - Open-label dose-escalation trial to evaluate the safety, pharmacokinetics, and pharmacodynamics of daily oral MGCD265 administered without interruption to subjects with advanced malignancies. Glaxo Smith Kline CRU - VEG108844 - A study of Pazopanib versus Sunitinib in the treatment of subjects with locally advanced and/or metastatic rena cell carcinoma. Hoffmann-La Roche Limitée, CRU - A multi-center, open-label, first-in-human, phase I doseCanada escalation study of single agent RO5503781, a small molecule MDM2 antagonist, administered orally in patients with advanced malignancies, except leukemia. Protcol no NP27872. Glaxo Smith Kline CRU - A rollover study to provide continued treatment with GSK2118436 to subjects with BRAF mutation-positive tumors. Astellas Pharma Canada, Inc. CRU - A phase I, open-label, multi-center study to assess the safety, pharmacokinetics and effectiveness of AGS-116C3F monotherapy in subjects with renal cell carcinoma of clear cell or papillary histology. Amgen Canada Inc (Mississauga, CRU-A phase 2, multicenter, single-arm trial to evaluate the Ont) biodistribution and shedding of talimogene laherparepvec in subjects with inresected, stage IIIb to IVM1a melanoma. Bristol-Myers Squibb Canada Inc. CRU - A randomized, open-label, phase 3 study of BMS-936558 vs. everolimus in subjects with advanced or metastic clear-cell renal cell carcinoma who have received prior anti-angiogenic therapy. Medpace Inc. CRU - An international phase 3 randomized trial of autologous dendritic cell immunotherapy (AGS 003) plis standard treatment of advanced renal cell carcinoma (ADAPT). Glaxo Smith Kline CRU - BRF113683: a phase III randomized, ope-label study comparing GSK2118436 to DTIC in previously untreated subjects with BRAF mutation positive advanced (stage III) or metastatic (stage IV) melanoma. Novartis Pharmaceuticals CRU - A phase Ib/II, multicenter, study of LEE011 in combination with Corporation lgx818 in adult patients with BRAF mutant melanoma. Novartis Pharmaceuticals CRU-CLGX818X2109 - The LOGIC 2 Trial - A phase II, multi-center, Corporation open-label study of sequential LGX818/MEK162 combination followed by a rational combination with targeted agents after progression, to overcome resistance in adult patients with locally Hoffmann-La Roche Limitée, CRU-A multiple-center, open-label clinical pharmacology study with Canada RO5503781 an MDM2 antagonist, in patients with solid tumors to determine: Part 1- One-sequence, 2-period crossover design to investigate the effect of posaconazole, a strong CYP3A4 inhibit Bristol-Myers Squibb Canada Inc. CRU - CA209-037: A randomized, open-label phase III trial of BMS936558 versus investigator's choice in advanced (unresectable or metastic) melanoma patients progressing post anti-CTLA-4b therapy. Bristol-Myers Squibb Canada CRU - A phase Ib/II, multicenter, open-label, dose escalation study of Inc.Novartis Pharma Canada Inc. LGX818 in combination with MEK162 in adult patients with BRAF V600 dependent advanced solid tumors. 11,000 60,500 34,395 22,547 153,000 1,322 6,629 2 860 1,500 2,800 4,868 7,050 8,668 12,526 14,891 36,208 58,426 111,500 137,120 229,917 21 MILLER, Wilson Merck Frosst Canada Inc OUGHTON, Matthew POLLAK, Michael IntelligentMDx (IMDx) Teva Pharma Industries CDA POLLAK, Michael Hanall Biopharma RICHARDS, Brent RICHARDS, Brent RICHARDS, Brent RUDSKI, Lawrence King's College London Glaxo Smith Kline Eli Lilly Canada Inc. Canadian Heart Research Center RUDSKI, Lawrence Genzyme Canada SCHIFFRIN, Ernesto Institut Servier (L') (France) SCHIPPER, Hyman Morris Immunotec Recherche SHEPPARD, Richard Bristol-Myers Squibb Canada Inc.Novartis Pharma Canada Inc. SHEPPARD, Richard Janssen Pharmaceutica Inc SHEPPARD, Richard bioMérieux sa (France) SHEPPARD, Richard Bayer Canada Inc. SIRHAN, Shireen YM BioSciences Inc. SIRHAN, Shireen INC Research SIRHAN, Shireen Sanofi-Aventis (Canada) SIRHAN, Shireen Gilead Sciences SIRHAN, Shireen Gilead Sciences THERRIEN, Judith Hamilton Health Sciences TRIFIRO, Mark A Bristol-Myers Squibb Canada Inc. TRIFIRO, Mark A Genome Prairie CRU-A multicenter, randomized, controlled, three-arm, phase III study to evaluate the safety and efficacy of two dosing schedules of MK-3475 compared to ipilimumab in patients with advanced melanoma. Contract for the selection of clinical specimens. CRU - A randomized phase 3 comparing standard first-line Docetaxel/Prednisone to Docetaxe/Prednisone in combination with Custirsen (OGX-011) in men with metastatic castrate resistant prostate cancer. The study involves in vitro and in vivo assays and no human participants are to be in invloved in the study and characterization of novel biguanides. Standard operating procedures. Repisitioning existing therapies to new diseases. Collaborative Agreement. Acute coronary syndromes quality enhancement research initiative III. ACS III QuERI. Prevalence of Anderson-fabry disease (AFD) in multiple high risk populations in a single hospital-based setting. Gene expression profile in small resistance arteries in patients with hypertension with or without nephroangiosclerosis and its relation to small and large artery function and remodeling. Immunocal Prophylaxis in the GFAP.HMOX1 mouse model of neurodevelopmental and neurodegenerative disorders - Phase 1 and Phase 2. A multicenter, randomized, double-blind, parallel-group, activecontrolled study to evaluate the efficacy and safety of LCZ696 compared to enalapril on morbidity and mortality in patients with chronic heart failure and reduced injection fraction. A randomized, double-blind, event-driven, multicenter study comparing the efficacy and safety of oral Rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with chronic heart failure and significant coronary Galectin-3 as an early and sensitive marker for anthracyclines (with or without Trastuzumab) and Tyrosine kinase inhibitor induced cardiotoxicity A randomized, double-blind, double-dummy, multi-center study to assess safety and efficacy of BAY-94-8862 in subjects with emergency presentation at the hospital because of worsening chronic heart failure with left ventribular systolic dysfunction and CRU - A phase II, open-label extension study evaluating the long-term safety, tolerability and efficacy of orally-administered CYT387 in primary myelofibrosis or post-polycythemia vera or post-essential thrombocythemia myelofibrosis (CCL09101E). CRU - An open-label, multiple simon 2-stage study of INCB039110 administered orally to subjects with primary myelofibrosis (PMF), post polycythemia vera-myelofibrosis (PPVMF) or post essential thrombocythemia-myelofibrosis (PET-MF). CRU-ARD12042-A randomized phase II, open-label study of the efficacy and safety of orally administered SAR302503 in patients with polycythemia vera (PV) or essential thrombocythemia (ET) who are resistant or intolerant to hydroxyurea. CRU-A phase 2, open-label, randomized study to evaluate the safety and efficacy of momelotinib in subjects with plycythemia vera or essential thrombocythemia. CRU-Open-label study to assess the long-term safety and efficacy of momelotinib in subjects with primary myelofibrosis, post-polycythemia vera myelofibrosis, post-essential thrombocythemia myelofibrosis, polycythemia vera or essential thrombocythemi. BAV - Beta-blockers and angiotensin receptor blockers in bicuspid aortic valve aortopahy. A double-blind placebo-controlled, randomized, two stage, parallelgroup, adaptive design phase 2a study to evaluate the effects of BMS813160 in subjects with type 2 diabetes mellitus Total utilization flax genomics (TUFGEN). 462,907 7,510 11,038 30,000 8,307 48,323 111,610 2,000 19,245 314,978 47,617 2,425 4,000 17,038 44,448 2,422 7,302 9,705 9,800 29,926 7,465 10,300 15,000 22 VAITEKUNAS, Susan Servier Canada Inc WAINBERG, Mark A. Merck Sharp & Dohme Research Laboratory Clinical Research Awards Chen-Tournoux, A Department of Medicine, JGH Cohen, A Dascal, A Department of Medicine, JGH Department of Medicine, JGH Galiatsatos, P Department of Medicine, JGH Greenaway, C. Joyal, D Langleben, D Department of Medicine, JGH Department of Medicine, JGH Department of Medicine, JGH Levinoff, E. Department of Medicine, JGH Palayew, M. Department of Medicine, JGH Roshdy, O. Department of Medicine, JGH Rudski, L. Saad, N. Department of Medicine, JGH Department of Medicine, JGH Schweitzer, M. Department of Medicine, JGH Sebag, I Department of Medicine, JGH Szilagyi, A. Department of Medicine, JGH Tagalakis, V. Tamilia, M Department of Medicine, JGH Department of Medicine, JGH Teltscher, M. Therrien, J Department of Medicine, JGH Department of Medicine, JGH Wyse, J. TOTALS Department of Medicine, JGH 251 Efficacy and safety of 3 doses of S 38093(2,5 and 20 mg/day) versus placebo in co-administration with donepezil (10 mg/day) in patients with moderate Alzheimer's Disease. A 24-week international, multi-centre, randomised, double-blind, placebo-controlled Part 1: Impact of subtype-specific variability on hte effectiveness of integrase inhibitor. 158,008 Echocardiographic quantification of epicardial fat and its implications for cardiovascular risk Inflammatory bowel disease rapid access clinic Microbiome Replenishment Strategies to Treat and Protect against C difficile Impact of Lynch syndrome on career pursuits, professional development, and academic studies The Burden of Viral Hepatitis in Migrants: A Population based Study Novel techniques in chronic total occlusions (CTO) recanalization Assessment of recruitment of functional pulmonary microvascular surface area in the determination of exercise limitation in patients with pulmonary arterial hypertension Cognitive Impairment and Post-operative Outcomes in Elderly Individuals The Airways Centre at the Jewish General Hospital: Aspects of care in COPD patients Analysis of the direct growth inhibitory effect of ipilimumab on melanoma cells Echocardiography-based research on the right heart Chronic Obstructive Pulmonary Disease (Copd) and Pulmonary Rehabilitation Niemann-Pick C1-like (NPC1L1) structure/function analysis in a family of disparate ezetimibe responders Matrix-array imaging for real-time, three-dimensional echocardiography and evolving techniques in cardiac mechanics IBD Epidemiology: Relationships with Vitamin D and population lactase distributions Venous thrombosis: Epidemiology and Cancer The role of oncogenic and epigenic events in the prediction of invasiveness and aggressiveness of differentiated thyroid carcinoma Fecal Microbiota Transplant for the Treatment of C Difficile Infection Beta Blockers and Angiotensin Receptor Blockers in Bicuspid Aortic Valve Disease Aortopathy The value of Botox-A in Acute Radiation Proctitis 12,000 12,000 4,000 12,000 12,000 12,000 12,000 8,000 4,000 4,000 12,000 8,000 12,000 12,000 4,000 12,000 12,000 8,000 12,000 27,568,152 2,927,850 4,000 188,000 4,174,821 23