ÉTATS-UNIS
Transcription
ÉTATS-UNIS
GUIDE DE L’EXAMEN MÉDICAL PÉRIODIQUE Adolescent - Adulte NOVEMBRE 2004 Mise à jour : janvier 2010 Préparé par Dre Guylène Thériault UMF de Gatineau 2 | Umf de Gatineau Pour chaque thème il y a la recommandation du Groupe d’étude canadien sur les soins de santé préventifs et/ou celle de son équivalent américain. Les recommandations de groupes de travail ou d’associations qui semblaient pertinentes ont aussi été retranscrites. Pour assurer la fiabilité de la retranscription la langue d’origine a été conservée. L’immunisation n’a pas été abordée dans son ensemble. Le PIQ étant selon moi une excellente référence (souvent mise à jour et fiable). Les problématiques liées à la grossesse ou aux problèmes dentaires ne sont pas couvertes. Dans les feuilles synthèses, les recommandations qui datent de plus de 15 ans seront considérées comme non actives et représentées par un *. Un * souligne la nécessité de consulter ce guide. Soit qu’il existe une recommandation d’un autre organisme ou que la seule recommandation date de plus de 15 ans. Remerciements à Dre Cléo Mavriplis pour sa participationà la version originale de 2004. Dr Gilles Brousseau pour les feuilles sommaires et son aide précieuse au fil des ans. Dre Guylaine Proulx, Dre Marie-Claude Dupras, Dre Helène Bureau et Dre Louise Guay pour leurs commentaires. Dr Isabelle Gagnon et Dr Zineb El-Merzouar pour leurs commentaires sur la feuille sommaire plus de 70 ans Patricia Rhéaume, Irène Veilleux, Suzanne Lessard et Pierre Lebrun pour leur soutien technique. Guide de l’examen médical périodique – révision janvier 2010 | 3 4 | Umf de Gatineau Table des matières MALADIES MÉTABOLIQUES ET NUTRITIONNELLES ..................................................................................... 9 GLYCEMIE (DEPISTAGE DU DIABETE) ........................................................................................................................ 9 CHOLESTÉROL ........................................................................................................................................................ 10 TENSION ARTÉRIELLE .............................................................................................................................................. 12 OSTEOPOROSE ....................................................................................................................................................... 13 TSH......................................................................................................................................................................... 14 HÉMOCHROMATOSE ................................................................................................................................................ 15 CANCERS.................................................................................................................................................................. 17 CANCER DU SEIN ..................................................................................................................................................... 17 CANCER DU COLON (RECHERCHE DE SANG OCCULTE DANS LES SELLES) ............................................................ 19 CANCER DU COL DE L’UTÉRUS ................................................................................................................................ 21 CANCER DE LA PROSTATE....................................................................................................................................... 22 CANCER DES TESTICULES ....................................................................................................................................... 24 CANCER DU POUMON .............................................................................................................................................. 25 VESSIE ..................................................................................................................................................................... 26 OVAIRES .................................................................................................................................................................. 26 PANCRÉAS............................................................................................................................................................... 26 ORAL ....................................................................................................................................................................... 26 PEAU ....................................................................................................................................................................... 27 THYROÏDE ................................................................................................................................................................ 27 MALADIES INFECTIEUSES................................................................................................................................... 29 ITSS (COUNSELLING)............................................................................................................................................. 29 CHLAMYDIA.............................................................................................................................................................. 29 GONORRHÉE ........................................................................................................................................................... 31 SYPHILIS .................................................................................................................................................................. 32 HIV .......................................................................................................................................................................... 33 HÉPATITES .............................................................................................................................................................. 34 HERPES ................................................................................................................................................................... 35 HUMAN PAPILLOMA VIRUS INFECTION ..................................................................................................................... 36 RUBÉOLE ................................................................................................................................................................. 36 TUBERCULOSE ........................................................................................................................................................ 36 BACTÉRIURIE ........................................................................................................................................................... 37 VARICELLE............................................................................................................................................................... 37 HABITUDES DE VIE ................................................................................................................................................ 39 TABAC...................................................................................................................................................................... 39 ALCOOL ................................................................................................................................................................... 39 ACTIVITÉ PHYSIQUE................................................................................................................................................. 39 DIÈTE ....................................................................................................................................................................... 40 OBÉSITÉ .................................................................................................................................................................. 40 PRÉVENTION DES ACCIDENTS .......................................................................................................................... 43 PERSONNES ÂGÉES ................................................................................................................................................ 44 MCAS ..................................................................................................................................................................... 45 ASPIRINE PREVENTION PRIMAIRE............................................................................................................................ 45 ASPIRINE PRÉVENTION SECONDAIRE ...................................................................................................................... 46 DIABETES ................................................................................................................................................................ 46 HYPERTENSION ....................................................................................................................................................... 47 DÉPISTAGE MCAS.................................................................................................................................................. 48 VITAMINE E.............................................................................................................................................................. 48 MALADIES VASCULAIRES ................................................................................................................................... 49 ANÉVRYSME DE L’AORTE ABDOMINALE ................................................................................................................... 49 Guide de l’examen médical périodique – révision janvier 2010 | 5 STÉNOSE CAROTIDIENNE ........................................................................................................................................ 49 MVAS ..................................................................................................................................................................... 49 TROUBLES DE LA VISION OU DE L’AUDITION............................................................................................... 50 VISION ..................................................................................................................................................................... 50 GLAUCOME .............................................................................................................................................................. 50 SURDITÉ .................................................................................................................................................................. 51 SANTÉ MENTALE.................................................................................................................................................... 51 DROGUES ................................................................................................................................................................ 51 DÉPRESSION IN ADULTS .......................................................................................................................................... 51 DÉPRESSION IN ADOLESCENTS ............................................................................................................................... 52 DÉMENCE ................................................................................................................................................................ 52 VIOLENCE FAMILIALE ............................................................................................................................................... 53 MALADIES CHRONIQUES..................................................................................................................................... 53 MPOC..................................................................................................................................................................... 53 SANTÉ DE LA FEMME ........................................................................................................................................... 55 CONTRACEPTION..................................................................................................................................................... 55 ACIDE FOLIQUE EN PRECONCEPTION ...................................................................................................................... 55 CHIMIOPROPHYLAXIE CONTRE LE CANCER DU SEIN ............................................................................................... 55 HORMONOTHÉRAPIE ............................................................................................................................................... 55 ANNEXE 1.................................................................................................................................................................. 59 FEUILLES SYNTHESE DES RECOMMANDATIONS ...................................................................................................... 59 ANNEXE 2.................................................................................................................................................................. 61 SUGGESTION DE FEUILLES DE PRISE DE DONNEES POUR L’EXAMEN PERIODIQUE ADOLESCENT-ADULTE ............ 61 ANNEXE 3.................................................................................................................................................................. 63 SUGGESTION DE FEUILLES SOMMAIRES ................................................................................................................. 63 ANNEXE 4.................................................................................................................................................................. 65 CRITERES POUR LES RECOMMANDATIONS DES DIVERS GROUPES ........................................................................ 65 ANNEXE 5.................................................................................................................................................................. 71 SCORE................................................................................................................................................................... 71 ORAI ....................................................................................................................................................................... 71 TABLEAU DU GUIDE DE DÉPISTAGE DES ITSS ............................................................................................ 73 6 | Umf de Gatineau Recommandations Maladies métaboliques et nutritionnelles Prévention des accidents Glycémie (dépistage du diabète) Cholestérol Tension artérielle Ostéoporose TSH Hémochromatose MCAS Maladies vasculaires Cancers Sein Côlon (recherche de sang dans les selles) Col utérin Prostate Testicules Poumon Vessie Ovaires Pancréas Oral Peau Thyroïde Maladies infectieuses Chlamydia Gonorrhée Syphilis HIV Hepatites (B et C) Herpes Human papilloma virus Rubéole Tuberculose Bactériurie Varicelle Habitudes de vie Tabac Alcool Diète Obésité Activité physique Aspirine (prévention primaire) Dépistage Vitamine E Anévrysme de l’aorte abdominale Sténose carotidienne MVAS Troubles de la vision ou de l’audition Vision Glaucome Surdité Santé mentale Drogues Depression Démence Maladies chroniques MPOC Santé de la femme Contraception Acide folique préconception Chimioprophylaxie pour le cancer du sein Hormonothérapie ANNEXES Annexe 1 Feuilles synthèse des recommandations par sexe et groupe d’âge Annexe 2 Suggestions de feuilles de prise de données pour l’examen périodique adulte Annexe 3 Feuilles sommaires Annexe 4 Critères pour les recommandations des différents groupes Annexe 5 SCORE, ORAI Guide de l’examen médical périodique – révision janvier 2010 | 7 8 | Umf de Gatineau MALADIES MÉTABOLIQUES ET NUTRITIONNELLES Glycémie (dépistage du diabète) CANADA 1) CTFPHC 2005: There is fair evidence to recommend screening adults with hypertension or hyperlipidemia for type 2 diabetes mellitus to prevent cardiovascular events and death (Recommandation B) There is good evidence to recommend lifedtyle interventions for overweight individuals (BMI>25 or >22 if on asian descent) with impaired glucose tolerance to reduce the incidence of progression to diabetes (Recommandation B) There is fair evidence to recommend acarbose treatment for overweight individuals (as above) with impaired glucose tolerance to prevent cardiovascular events and hypertension (Recommandation B) There is insufficient evidence to recommend metformin or acarbose treatment for overweight individuals with impaired glucose tolerance to prevent diabetes progression (Recommandation I) 1993 : Good evidence to include dipstick screening for protein in the PHE of adults with IDDM. (Recommandation A) 2) Association canadienne du diabète 2008 All individuals should be evaluated annually for type 2 diabetes risk on the basis of demographic and clinical criteria ( Grade D Consensus) Screening for diabetes using an FPG should be performed every 3 years in individuals ≥ 40 years of age (Grade D Consensus) More frequent and/or earlier testing with either an FPG or a 2hPG in a 75-g OGTT should be considered in people with additionnal risk factors for diabetes (Grade D Consensus) These risk factors include : first degree relative with type 2 diabetes, member of high risk population (e.g. people of Aboriginal, Hispanic, Asian, South-Asian or African descent), history of IGT or IFG, presence of complications associated with diabetes, vascular disease (coronary, cerebrovascular or peripheral), history of gestationnal diabetes mellitus, History of delivery of a macrosomic infant, hypertension, dyslipidemia, overweight, abdominal obesity, polycystic ovary syndrome, acanthosis nigricans, schizophrénia and others ÉTATS-UNIS 1) USPSTF 2008 The USPSTF recommands screening for type 2 diabetes in asymptomatic adults with sustained blood pressure (either treated or untreated) greater than 135/80 mm Hg (Recommandation B) The USPSTF concludes than the current evidence is insufficient to assess the balance of benefits and harms of screening for type-2 diabetes in asymptomatic adults with blood pressure of 135/80 mmHg or lower (Recommandation I) Screening may be considered on an individual basis if knowledge of diabetes status would help inform decisions about coronary heart disease (CHD) prevention strategies, including assessment of CHD risk and subsequent consideration of lipidlowering agents or aspirin.The optimal screening interval is not known. Guide de l’examen médical périodique – révision janvier 2010 | 9 2) American diabetes association 2010 Criteria for testing for diabetes in asymptomatic individuals Testing should be considered in all adults who are overweight (BMI ≥25 kg/m2*) and have additional risk factors: physical inactivity, first-degree relative with diabetes, members of a highrisk ethnic population (e.g., African American, Latino, Native American, Asian American, Pacific Islander), women who delivered a baby weighing >9 lb or were diagnosed with GDM, hypertension (≥140/90 mmHg or on therapy for hypertension), HDL cholesterol level <35 mg/dl (0.90 mmol/l) and/or a triglyceride level >250 mg/dl (2.82 mmol/l), women with polycystic ovary syndrome, A1C ≥5.7%, IGT, or IFG on previous testing, other clinical conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans), history of CVD. In the absence of the above criteria, testing diabetes should begin at age 45 years. If results are normal, testing should be repeated at least at 3-year intervals, with consideration of more frequent testing depending on initial results and risk status. At-risk BMI may be lower in some ethnic groups 3) AACE 2007 Annually screen all individuals 30 years or older who are at risk of developing T2DM. Family history of dabetes, cardiovascular disease, overweight or obese state, sedentary lifestyle, Latino/Hispanic, Non-hispanic black, Asian american, Native american or pacific Islander ethnicity, previously impaired glucose tolerance or impaired fasting glucose, hypertension, increased level of triiiglycerides, low concentration of high density lipoprotein cholesterol or both, history of gestationnal diabetes, history of delivery of an infant with a birth weight > 9 pounds, polycystic ovarian disease, psychiatric illness. Cholestérol CANADA 1) CTFPHC 1994 (recommendation qui date de PLUS DE 15 ANS) Screening should be considered in all men aged 30 to 59 years; individual clinical judgement should be exercised in all other cases (Recommandation C) For men 30 to 59 years old with a mean total cholesterol level of more than 6.85 mmol/L or an LDL-C level of more than 4.50 mmol/L treatment is efficacious in reducing incidence of CHD. (Recommandation B) For all other asymptomatic individuals the value of treatment has not been demonstrated. (Recommandation C) 2) Canadian cardiovascular society 2009 Patients whose plasma lipid profile should be screened • Men ≥40 years of age, and women ≥50 years of age or postmenopausal • All patients with the following conditions, regardless of age: Diabetes, Hypertension, Current cigarette smoking, Obesity (Obesity Canada guidelines), Family history of premature CAD (<60 years in first-degree relatives), Inflammatory diseases* (systemic lupus erythematosis, rheumatoid arthritis, psoriasis), Chronic renal diseases (eGFR <60 mL/min/1.73 m2), Evidence of atherosclerosis, HIV infection treated with highly active antiretroviral therapy, Clinical manifestations of hyperlipidemias (xanthomas, xanthelasmas,premature arcus cornealis), Erectile dysfunction 10 | Umf de Gatineau 3) Association canadienne du diabète 2008 A fasting lipid profile (total cholesterol [TC], HDL-C,TG and calculated LDL-C) should therefore be conducted at the time of diagnosis of diabetes, and then every 1 to 3 years, as clinically indicated. More frequent testing should be conducted if treatment for dyslipidemia is initiated. ÉTATS-UNIS 1) USPSTF 2008 The U.S. Preventive Services Task Force (USPSTF) strongly recommends screening men aged 35 and older for lipid disorders (Recommandation A) The USPSTF recommends screening men aged 20 to 35 for lipid disorders if they are at increased risk for coronary heart disease. (Recommandation B) The USPSTF strongly recommends screening women aged 45 and older for lipid disorders if they are at increased risk for coronary heart disease. (Recommandation A) The USPSTF recommends screening women aged 20 to 45 for lipid disorders if they are at increased risk for coronary heart disease. (Recommandation B) The USPSTF makes no recommendation for or against routine screening for lipid disorders in men aged 20 to 35, or in women aged 20 and older who are not at increased risk for coronary heart disease (Recommandation C) The optimal interval for screening is uncertain. On the basis of other guidelines and expert opinion, reasonable options include every 5 years, shorter intervals for people who have lipid levels close to those warranting therapy, and longer intervals for those not at increased risk who have had repeatedly normal lipid levels. An age to stop screening has not been established. Screening may be appropriate in older people who have never been screened; repeated screening is less important in older people because lipid levels are less likely to increase after age 65. 2) NCEP III 2001 NCEP: National cholesterol education program (USA) In all adults aged 20 years or older, a fasting lipoprotein profile should be obtained once every five years (rien de nouveau sur dépistage dans update 2004) The American Heart Association has the same recommendation 3) AACE 2002 (American association of clinical endocrinologists) Screening for dyslipidemia is warranted for all adults up to 75 years of age regardless of CAD risk status and for adults more than 75 years old who have multiple CAD risk factors (if they have good quality of life and no other major life-limiting disease). For adult more than 20 years of age with no CAD risk factors the screening should be done every 5 years. (more often if CAD risk factors exist) 4) American diabetes association 2010 In most adult patients, measure fasting lipid profile at least annually. In adults with low-risk lipid values (LDL cholesterol <100 mg/dl, HDL cholesterol >50 mg/dl, and triglycerides <150 mg/dl), lipid assessments may be repeated every 2 years. (E) Guide de l’examen médical périodique – révision janvier 2010 | 11 Tension artérielle CANADA 1) CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Measurement of blood pressure (BP) level. Although not evaluated for its effectiveness, casefinding should be considered in all persons aged 21 to 64 years; Fair evidence to include in periodic health examination . (Recommandation B) Hypertension in the elderly: Screening for this condition can be confidently recommanded in those aged 65 to 84 years.(Recommandation B) Efficacy in treatment in treatment has not been demonstrated in those above 80. While definitive evidence for treatment of hypertension in those over 85 is lacking, it seems unlikely that judicious treatment will be detrimental 2) Canadian hypertension society 2009 The blood pressure (BP) of all adult patients should be assessed at all appropriate visits for determination of cardiovascular risk and monitoring of antihypertensive treatment by health care professionals who have been specifically trained to measure blood pressure accurately (Grade D). 3) Canadian diabetes association 2008 People with diabetes should be regularly screened (i.e. at every diabetes-related clinic visit) for the presence of hypertension, and those with elevated BP should be aggressively treated. ÉTATS-UNIS 1) USPSTF 2006: The U.S. Preventive Services Task Force (USPSTF) recommends screening for high blood pressure in adults aged 18 and older (Recommandation A) Evidence is lacking to recommend an optimal interval for screening adults for hypertension. 2) JNC VII (Joint national committee on prevention, detection, evaluation and treatment of high blood pressure) 2003: The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) recommends screening every 2 years in persons with blood pressure less than 120/80 mm Hg and every year with systolic blood pressure of 120 to 139 mm Hg or diastolic blood pressure of 80 to 90 mm Hg. 3) American diabetes association 2010 Blood pressure should be measured at every routine diabetes visit. Patients found to have systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg should have blood pressure confirmed on a separate day. Repeat systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg confirms a diagnosis of hypertension. (C) 12 | Umf de Gatineau Ostéoporose CANADA 1) CTFPHC 2004 Screening all postmenopausal women with a history of previous fracture, or who are 65 years or older, or have a ORAI score of 9 or a SCORE score of 6 with BMD by DEXA to prevent fragility fractures. (Recommandation B).For women without documented osteoporosis, there is fair evidence that calcium and vitamin D supplementation alone prevents osteoporotic fractures (Recommandation B) 2) Osteoporosis society of Canada 2002 Screening of all postmenopausal women or all men over age 50 is not justified according to available data. However, measuring bone density in men and women after the age of 65, recognizing that after this age fracture risk increases, is justifiable (level 3). Evidence for the use of bone measurement in men and in non-Caucasian women is meager. Existing data do not contradict the inferences already made (consensus). Targeted case-finding strategies for those at increased risk (at least one major or 2 minor risk factors) are recommended, and BMD measurement with central DXA at age 65 is recommended (Grade A). Daily intake of calcium : Femme 19-50 ans 1000mg/jr (Grade A) Femme >50 ans 1500 mg/jr (Grade A) Homme 19-50 ans 1000 mg/jr (Grade C) Homme >50 ans 1500 mg/jr (Grade C). Daily intake of vitamin D : Femme 19-50 ans 400UI (Grade D) Femme >50 ans 800UI (Grade A) Homme 19-50 ans 400UI (Grade D) Homme >50 ans 800UI (Grade A) Eviter >4 tasses café/jr (Grade B). ÉTATS-UNIS 1) USPSTF 2002 The U.S. Preventive Services Task Force (USPSTF) recommends that women aged 65 and older be screened routinely for osteoporosis. The USPSTF recommends that routine screening begin at age 60 for women at increased risk for osteoporotic fractures (Recommandation B) (Lower body weight (weight < 70 kg ) is the single best predictor of low bone mineral density.There is less evidence to support the use of other individual risk factors (for example, smoking, weight loss, family history, decreased physical activity, alcohol or caffeine use, or low calcium and vitamin D intake) as a basis for identifying high-risk women younger than 65 . The best validated instruments include the 3-item ORAI and the 6-item Simple Calculated Osteoporosis Risk Estimation tool (SCORE)) (voir annexe de la version papier ou SCORE http://www.geocities.com/HotSprings/8741/score2.html et ORAI http://www.cmaj.ca/cgi/content/full/162/9/1289/T414) The USPSTF makes no recommendation for or against routine osteoporosis screening in postmenopausal women who are younger than 60 or in women aged 60-64 who are not at increased risk for osteoporotic fractures (Recommandation C) No studies have evaluated the optimal intervals for repeated screening. Because of limitations in the precision of testing, a minimum of 2 years may be needed to reliably measure a change in bone mineral density; however, longer intervals may be adequate for repeated screening to identify new cases of osteoporosis. Yield of repeated screening will be higher in older women, those with lower BMD at baseline, and those with other risk factors for fracture There are no data to determine the appropriate age to stop screening and few data on osteoporosis treatment in women older than 85. Guide de l’examen médical périodique – révision janvier 2010 | 13 2) National osteoporosis foundation 2008 All postmenopausal women and men age 50 and older should be evaluated clinically for osteoporosis risk in order to determine the need for BMD testing. In general, the more risk factors that are present, the greater the risk of fracture. Since the majority of osteoporosis-related fractures result from falls, it is also important to evaluate risk factors for falling. NOF recommends testing of all women age 65 and older and men age 70 and older regardless of their risk factors, younger postmenopausal women and men age 50 to 69 about whom you have concern based on their clinical risk factor profile, women in the menopausal transition if there is a specific risk factor associated with increased fracture risk such as low body weight, prior lowtrauma fracture or high risk medication, adults who have a fracture after age 50, Adults with a condition (e.g., rheumatoid arthritis) or taking a medication(e.g.,glucocorticoids in a daily dose ≥ 5 mg prednisone or equivalent for ≥three months) associated with low bone mass or bone loss, anyone being considered for pharmacologic therapy for osteoporosis. NOF supports the National Academy of Sciences (NAS) recommendation that women older than age 50 consume at least 1,200 mg per day of elemental calcium. Intakes in excess of 1,200 to 1,500 mg per day have limited potential for benefit and may increase the risk of developing kidney stones or cardiovascular disease. Calcium supplements should be used when an adequate dietary intake cannot be achieved. NOF recommends an intake of 800 to1,000 international units (IU) of vitamin D per day for adults age 50 and older. TSH CANADA CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Poor evidence for either inclusion or exclusion of TSH screening (Recommandation C); due to the high prevalence of thyroid disorders in peri-menopausal women, physicians should maintain a high index of clinical suspicion. ÉTATS-UNIS USPSTF 2004 The USPSTF concludes the evidence is insufficient to recommend for or against routine screening for thyroid disease in adults (Recommandation I) 14 | Umf de Gatineau Hémochromatose ETATS-UNIS USPSTF 2006 The U.S. Preventive Services Task Force (USPSTF) recommends against routine genetic screening for hereditary hemochromatosis in the asymptomatic general population. (Recommandation D) Guide de l’examen médical périodique – révision janvier 2010 | 15 16 | Umf de Gatineau CANCERS Cancer du sein CANADA 1) CTFPHC 1998: There is good evidence for screening women aged 50-69 years by clinical examination and mammography (Recommandation A). The best available data support screening every 1-2 years. 2001: Current evidence does not support the recommendation that screening mammography be included in or excluded from the periodic health examination of women aged 40-49 at average risk of breast cancer (Recommandation C) Upon reaching the age of 40, Canadian women should be informed of the potential benefits and risks of screening mammography and assisting in deciding at what age they wish to initiate it. Comparison of RCT results suggests that, if done, frequent screening may be required (Mammography every 12-18 months) 2001: Because there is fair evidence of no benefit, and good evidence of harm, there is fair evidence to recommend that routine teaching of BSE be excluded from the periodic health examination of women aged 40–69 (Recommandation D) 2) Société canadienne du cancer Si vous êtes âgée de 50 à 69 ans, passez une mammographie tous les 2 ans. Si vous avez entre 40 et 49 ans, discutez avec votre médecin de votre risque personnel de cancer du sein ainsi que des avantages et inconvénients de la mammographie. Si vous avez 70 ans ou plus, demandez à votre médecin ce qu’il vous conseille en matière de dépistage. Si vous avez plus de 40 ans, passez un examen clinique des seins, effectué par un professionnel de la santé compétent, au moins une fois tous les 2 ans. ÉTATS-UNIS 1) USPSTF 2005 The USPSTF recommends that women whose family history is associated with an increased risk for deleterious mutations in BRCA1 or BRCA2 genes be referred for genetic counselling and evaluation for BRCA testing (Recommandation B) For non-Ashkenazi Jewish women, these patterns include 2 first-degree relatives with breast cancer, 1 of whom received the diagnosis at age 50 years or younger; a combination of 3 or more first- or second-degree relatives with breast cancer regardless of age at diagnosis; a combination of both breast and ovarian cancer among first- and second-degree relatives; a first-degree relative with bilateral breast cancer; a combination of 2 or more first- or second-degree relatives with ovarian cancer regardless of age at diagnosis; a first- or second-degree relative with both breast and ovarian cancer at any age; and a history of breast cancer in a male relative. For women of Ashkenazi Jewish heritage, an increased-risk family history includes any first-degree relative (or 2 second-degree relatives on the same side of the family) with breast or ovarian cancer. Guide de l’examen médical périodique – révision janvier 2010 | 17 2) USPSTF 2009 The USPSTF recommends biennial screening mammography for women aged 50 to 74 years. (Recommandation B) The decision to start regular, biennial screening mammography before the age of 50 years should be an individual one and take patient context into account, including the patient's values regarding specific benefits and harms. (Recommandation C) The USPSTF concludes that the current evidence is insufficient to assess the additional benefits and harms of screening mammography in women 75 years or older. (Recommandation I) The USPSTF recommends against teaching breast self-examination (BSE). (Recommandation D) The USPSTF concludes that the current evidence is insufficient to assess the additional benefits and harms of clinical breast examination (CBE) beyond screening mammography in women 40 years or older. (Recommandation I) 3) ACOG 2003 The following recommandations are based on limited and inconsistent scientific evidence (Level B) : Women aged 40-49 years should have screening mammography every 1-2 years. Women aged 50 years and older should have annual mammography. The following recommandations are based primarly on consensus and expert opinion (level C) : Despite a lack of definitive data for or against breast self examination, breast self examination has the potential to detect palpable breast cancer and can be recommanded. All women should have clinical breast examination annually as part of the physical examination. 4) American geriatrics society 2005 For women in average to better health, with a life expectancy of 5 or more years, it is appropriate to offer screening mammography every one to two years to age 85. The recommandation should include an individualized review of the potential benefits and harms of screening and patients personnal preferences. Mammography screening beyond the age of 85 should be reserve for those women more likely to benefit by virtue of execellent health and fonctionnal status, and for those who feel strongly that they will benefit from such screening, either in peace of mind or improved quality of life. Clinical breat examination should be performed periodically. COCHRANE 2006 Sreening likely reduces breast cancer mortality. Based on all trials, the reduction is 20%, but as the effect is lower in the highest quality trials, a more reasonable estimate is a 15% relative risk reduction. Based on the risk level of women in these trials, the absolute risk reduction was 0.05%. Screening also leads to overdiagnosis and overtreatment, with an estimated 30% increase, or an absolute risk increase of 0.5%. This means that for every 2000 women invited for screening throughout 10 years, one will have her life prolonged. In addition, 10 healthy women, who would not have been diagnosed if there had not been screening, will be diagnosed as breast cancer patients and will be treated unnecessarily. It is thus not clear whether screening does more good than harm. Women invited to screening should be fully informed of both benefits and harms. 18 | Umf de Gatineau Cancer du colon (Recherche de sang occulte dans les selles) CANADA 1) CTFPHC 2001 Good evidence to include screening with annual or biennial Hemoccult test in the periodic health examination (PHE) of patients >50 (Recommandation A) 2) Canadian association of gastroenterologists 2004 Average risk: FOBT every two years. The AGA guidelines recommand screening yearly using a guaiac-test with dietary restrictions or a immunochemical test for heme without restrictions. The Canadian expert panel commissioned by Health Canada recommanded occult blood testing every two years. Although yearly occult blood testing does increase the detection of cancer, it was not felt that this justified the resulting considerable increase in work load Above average risk: 1) One first degree relative with cancer or adenomatous polyp at age< 60 or two or more first degree relatives with polyp or colon cancer at any age: colonoscopy every five years. Begin at age 40 or ten years earlier than the youngest diagnosis of polyp or cancer in the family which ever comes first. 2) One first degree relative with cancer or adenomatous polyp affected at age >60 or two or more second degree relatives with polyps or cancer: average risk screening but begin at age forty 3) National committee on colorectal cancer sreening (Health Canada 2002) Screening should be offered to adults 50-74 years old using FOBT. Individuals should be screened at least every two years recognising that annual screening would have slight improvement in mortality reduction but require increased resources. ÉTATS-UNIS 1) USPSTF 2008 The USPSTF recommends screening for colorectal cancer (CRC) using fecal occult blood testing, sigmoidoscopy, or colonoscopy, in adults, beginning at age 50 years and continuing until age 75 years. The risks and benefits of these screening methods vary (Recommandation A) The USPSTF recommends against routine screening for colorectal cancer in adults age 76 to 85 years. There may be considerations that support colorectal cancer screening in an individual patient (Recommandation C) The USPSTF recommends against screening for colorectal cancer in adults older than age 85 years (Recommandation D) The USPSTF concludes that the evidence is insufficient to assess the benefits and harms of computed tomographic colonography and fecal DNA testing as screening modalities for colorectal cancer (Recommandation I) 2002 The USPSTF found good evidence that periodic fecal occult blood testing (FOBT) reduces mortality from colorectal cancer. 2007 The USPSTF recommends against the routine use Guide de l’examen médical périodique – révision janvier 2010 | 19 of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) to prevent colorectal cancer in individuals at average risk for colorectal cancer.(Recommandation D) 2) American Gastroenterological Association 2008 The following options are acceptable choices for colorectal cancer screening in average-risk adults beginning at age 50 years. Since each of the following tests hasinherent characteristics related to prevention potential, accuracy, costs, and potential harms, individuals should have an opportunity to make an informed decision when choosing one of the following options. Tests that are designed to detect both early cancer and adenomatous polyps (like sigmoidoscopy q 5 years, colonoscopie q 10 ans, barium enema q 5 ans, colono virtuelle q 5 ans) should be encouraged if resources are available and patients are willing to undergo an invasive test. Annual screening with high-sensitivity gFOBT (such as Hemoccult SENSA) that have been shown in the published, peer-reviewed literature to detect a majority of prevalent CRC in an asymptomatic population is an acceptable option for colorectal screening in average-risk adults aged 50 years and older. Any positive test should be followed up with colonoscopy. Familial history : 1) histoire de cancer du colon ou de polype adénomateux chez un parent de 1er degré de moins de 60 ans OU 2 parents de 1er degre peu importe l’âge : colonoscopie aux 5 ans débutant à 40 ans ou 10 ans avant le cas le plus jeune. 2) histoire de cancer du colon ou de polype adénomateux chez un parent du premier degré de plus de 60 ans OU cancer du colon chez 2 parents du 2eme degré : dépistage comme pour la personne de risque moyen mais débutant à 40 ans. COCHRANE 2007 Benefits of screening include a modest reduction in colorectal cancer mortality, a possible reduction in cancer incidence through the detection and removal of colorectal adenomas, and potentially, the less invasive surgery that earlier treatment of colorectal cancers may involve. Harmful effects of screening include the psycho-social consequences of receiving a false-positive result, the potentially significant complications of colonoscopy or a false-negative result, the possibility of overdiagnosis (leading to unnecessary investigations or treatment) and the complications associated with treatment. 20 | Umf de Gatineau Cancer du col de l’utérus CANADA CTFPHC 1992 (recommandation qui date de PLUS DE 15 ANS) Pap: Fair evidence to include in periodic health examination of sexually active women. (Recommandation B) Annual screening is recommended following initiation of sexual activity or age 18; after 2 normal smears, screen every 3 years to age 69. Consider increasing frequency for women with risk factors: age of first sexual intercourse < 18 yrs, many sexual partners or consort with many partners, smoking or low socioeconomic status. SOGC 2007 No Quebec guidelines but national guidelines as above. There is no indication for cervical screening before initiation of sexual activity, regardless of age. Women who have undergone total hysterectomy for benign conditions, do not have a history of cervical dysplasia, and have a negative and adequate prior screening history do not require screening after their hysterectomy. INSPQ 2009 Le dépistage devrait débuter à 21 ans, à moins de circonstances exceptionnelles (âge très précoce des premières relations sexuelles, abus sexuel, immunosuppression ou infection par le VIH). Les tests de dépistage seraient espacés aux 2 ans, lorsque les résultats sont normaux. Le dépistage pourrait être cessé à 69 ans chez les femmes ayant au moins un test négatif au cours des 10 dernières années. ÉTATS-UNIS 1) USPSTF 2003 The USPSTF strongly recommends screening for cervical cancer in women who have been sexually active and have a cervix. (Recommandation A) Indirect evidence suggests most of the benefit can be obtained by beginning screening within 3 years of onset of sexual activity or age 21 (which ever comes first) and screening at least every 3 years. The USPSTF found no direct evidence that annual screening achieves better outcomes than screening every 3 years. The American Cancer Society guidelines suggest waiting until age 30 before lengthening the screening interval. Although there is little value in screening women who have never been sexually active, many U.S. organizations recommend routine screening by age 18 or 21 for all women, based on the generally high prevalence of sexual activity by that age in the U.S. and concerns that clinicians may not always obtain accurate sexual histories The USPSTF recommends against routinely screening women older than age 65 for cervical cancer if they have had adequate recent screening with normal Pap smears and are not otherwise at high risk for cervical cancer (Recommandation D). The USPSTF recommends against routine Pap smear screening in women who have had a total hysterectomy for benign disease. (Recommandation D) The USPSTF concludes that the evidence is insufficient to recommend for or against the routine use of new technologies to screen for cervical cancer. (Recommandation I) Newer Food and Drug Administration (FDA)approved technologies, such as the liquid-based cytology (e.g., ThinPrep®), may have improved sensitivity over conventional Pap smear screening, but at a considerably higher cost and possibly with lower specificity. Guide de l’examen médical périodique – révision janvier 2010 | 21 2) ACOG 2009 Begin screening at age 21. Screen every 2 years between age of 21 and 29. After age 30 screen every 2 years unless 3 consecutive tests where negative than screen every 3 years.Stop screening around age 65-70 if there was 3 negative tests in the last 10 years. No screening for patients that had hysterectomy for benign reasons. Women with certain risk factors may need more frequent screening, including those who have HIV, are immunosuppressed, were exposed to diethylstilbestrol (DES) in utero, and have been treated for cervical intraepithelial neoplasia (CIN) 2, CIN 3, or cervical cancer. 3) American geriatrics society 2000 Regular pap smear screening at 1 to 3 year intervals until at least the age of 70 seems reasonable. Beyond age 70, there is little evidence for or against screening women who have been regularly screened in previous years. An older woman of any age who has never had a pap smear may be screened with at least two negative pap smears 1 year apart. Cancer de la prostate CANADA 1) CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Digital Rectal Examination (DRE) : Poor evidence to include or exclude DRE from the periodic health examination (PHE) for men over 50 years of age (Recommandation C) Prostate specific antigen (PSA) : Exclusion is recommended on the basis of low positive predictive value and the known risk of adverse affects associated with therapies of unproven effectiveness. Fair evidence to exclude routine screening with PSA from the periodic health examination of asymptomatic men over 50 years of age. (Recommandation D) 2) Collège des medecins du Quebec 1998 Il n’est pas recommandé d’utiliser systématiquement le dosage de l’APS et/ou le toucher rectal seuls ou combinés comme méthode de dépistage du cancer de la prostate, quel que soit l’âge du patient (catégorie D) Le patient qui manifeste un intérêt ou des craintes relativement au cancer de la prostate devrait rcevoir du counselling pour lui permettre de faire un choix éclairé. De fait, une incertitude persiste quant aux avantages et aux inconvénients de dépistage chez les individus appartenant à l’un des groupes suivants ▪ les hommes agés de 50à 69 ans et jouissant d’une espérance de vie supérieur à 10 ans ▪ les hommes agés de 40 ans et plus d’origine afroaméricaine ou les hommes de 40 ans et plus dont au moins un parent de premier degré a souffert d’un cancer de la prostate et qui jouissent d’une espérance de vie supérieure à 10 ans. Cependant les données actuelles ne permettent pas d’affirmer que le dépistage est plus efficace dans de telles circonstances (catégorie C). 22 | Umf de Gatineau ÉTATS-UNIS 1) USPSTF 2008 The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of prostate cancer screening in men younger than age 75 years. (Recommandation I) The USPSTF recommends against screening for prostate cancer in men age 75 years or older (Recommandation D) *(In men younger than age 75 years, the USPSTF found inadequate evidence to determine whether treatment for prostate cancer detected by screening improves health outcomes compared with treatment after clinical detection. The USPSTF found convincing evidence that treatment for prostate cancer detected by screening causes moderate-to-substantial harms, such as erectile dysfunction, urinary incontinence, bowel dysfunction, and death. These harms are especially important because some men with prostate cancer who are treated would never have developed symptoms related to cancer during their lifetime.There is also adequate evidence that the screening process produces at least small harms, including pain and discomfort associated with prostate biopsy and psychological effects of false-positive test results. Older men, AfricanAmerican men, and men with a family history of prostate cancer are at increased risk for diagnosis of and death from prostate cancer.1 Unfortunately, the previously described gaps in the evidence regarding potential benefits of screening also apply to these men.) If screening were to reduce deaths, PSA screening as infrequently as every 4 years could yield as much of a benefit as annual screening. Given the uncertainties and controversy surrounding prostate cancer screening in men younger than age 75 years, a clinician should not order the PSA test without first discussing with the patient the potential but uncertain benefits and the known harms of prostate cancer screening and treatment. Men should be informed of the gaps in the evidence and should be assisted in considering their personal preferences before deciding whether to be tested. 2) American urological association 2009 Patients need to be informed of the risks and benefits of testingbefore it is undertaken. The risks of overdetection and overtreatment should be included in thisdiscussion. Because there is now evidence from a randomized, controlled trial regarding a mortality decrease associated with PSA screening, the AUA is recommending PSA screening, for well-informed men who wish to pursue early diagnosis. (Baseline PSA age 40 years with anticipated lifespan of 10 or more years: PSA AND DRE) Cochrane 2006 Given that only two randomised controlled trials were included, and the high risk of bias of both trials, there is insufficient evidence to either support or refute the routine use of mass, selective or opportunistic screening compared to no screening for reducing prostate cancer mortality. Currently, no robust evidence from randomised controlled trials is available regarding the impact of screening on quality of life, harms of screening, or its economic value. Results from two ongoing large scale multicentre randomised controlled trials that will be available in the next several years are required to make evidence-based decisions regarding prostate cancer screening. Guide de l’examen médical périodique – révision janvier 2010 | 23 Cancer des testicules CANADA CTFPHC 1994 (recommendation qui date de PLUS DE 15 ANS) Insufficient evidence to include or exclude routine examination of testes either by physician or by patient self-examination from the periodic examination. (Recommandation C) ÉTATS-UNIS USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) recommends against routine screening for testicular cancer in asymptomatic adolescent and adult males. (Recommandation D) 24 | Umf de Gatineau Cancer du poumon CANADA CTFPH 2003 The CTFPHC concludes that there still is fair evidence to recommend against screening with chest X-ray asymptomatic people for lung cancer using chest radiographic examination (Recommandation D) The CTF concludes that there is insufficient evidence (in quantity and/or quality) to make a recommendation as to whether spiral CT scanning should be used for screening asymptomatic people for lung cancer; however other factors may influence decision-making (Recommandation I ) ÉTATS-UNIS USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to recommend for or against screening asymptomatic persons for lung cancer with either low dose computerized tomography (LDCT), chest x-ray (CXR), sputum cytology, or a combination of these tests. (Recommandation I) The USPSTF found fair evidence that screening with LDCT, CXR, or sputum cytology can detect lung cancer at an earlier stage than lung cancer would be detected in an unscreened population; however, the USPSTF found poor evidence that any screening strategy for lung cancer decreases mortality. Because of the invasive nature of diagnostic testing and the possibility of a high number of false-positive tests in certain populations, there is potential for significant harms from screening. Therefore, the USPSTF could not determine the balance between the benefits and harms of screening for lung cancer. Cochrane 2003 The current evidence does not support screening for lung cancer with chest radiography or sputum cytology. Frequent chest x-ray screening might be harmful. Further, methodologically rigorous trials are required. Guide de l’examen médical périodique – révision janvier 2010 | 25 Autres cancers Vessie CTFPHC 1993 (recommandation qui date de PLUS DE 15 ANS) Urine dipstick or microscopy for hematuria : Fair evidence to exclude from Periodic Health Examination (PHE) for general population (Recommandation D); poor evidence to include or exclude from the PHE for persons at high risk.* (Recommandation C ) (* High-risk groups are Males > 60 years of age who smoke or have smoked, and were employed in a trade that may have exposed them to aromatic amines. ) USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) recommends against routine screening for bladder cancer in adults. (Recommandation D) Ovaires CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Fair evidence to exclude screening for ovarian cancer by any means (ultrasound, pelvic exam, serum markers) for pre- and post-menopausal women. (Recommandation D) For High-Risk Women with >1 First-degree Relative with Ovarian Cancer : Insufficient evidence to recommend for or against screening. (Recommandation C) USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) recommends against routine screening for ovarian cancer.(Recommandation D) Pancréas CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) There is fair evidence that routine screening should be excluded from the periodic health examination. (Recommandation D) USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) recommends against routine screening for pancreatic cancer in asymptomatic adults using abdominal palpation, ultrasonography, or serologic markers. (Recommandation D) Oral CTFPHC 1999 Insufficient insufficient evidence to recommend inclusion or exclusion of screening for oral cancer by clinical examination of asymptomatic patients (Recommandation C) For high risk patients, annual examination by physician or dentist should be considered. Major risk factors include a history of tobacco use and excessive alcohol consumption 26 | Umf de Gatineau USPSTF 2004 the evidence is insufficient to recommend for or against routinely screening adults for oral cancer. (Recommandation I) Peau CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Total body skin examination : There is poor evidence to include or exclude from the periodic health examination (PHE) of the general population (Recommandation C ); there is fair evidence for the inclusion of total body skin examination for a very select sub-group of individuals. (Recommandation B) (For individuals at significantly increased risk (i.e. family melanoma syndrome (MM) first degree relative with melanoma) it is prudent to undertake regular examinations (dermatologists may be more accurate assessors).) Self-Exam : There is poor evidence to include or exclude in the periodic health examination. (Recommandation C ) Avoidance of sun exposure and protective clothing : On the basis of epidemiologic data and casecontrol studies, and prudence, there is fair evidence to include in the periodic health examination. (Recommandation B ) Sunscreens (for prevention of squamous cell and basal cell carcinoma; and malignant melanoma) : There is poor evidence for the inclusion or exclusion of advice on sunscreen use in the PHE to prevent squamous cell carcinoma, basal cell carcinoma and malignant melanoma. (Recommandation C) USPSTF 2009 : The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of using a whole-body skin examination by a primary care clinician or patient skin self-examination for the early detection of cutaneous melanoma, basal cell cancer, or squamous cell skin cancer in the adult general population. (Recommandation I) 2003 : The U.S. Preventive Services Task Force concludes that the evidence is insufficient to recommend for or against routine counselling by primary care clinicians to prevent skin cancer. (Recommandation I) AUTRES The American Cancer Society recommends cancer check-up including skin examination every 3 years for those aged 20-39 and annually after age 40. The American Academy of Dermatology recommends annual screening for all patients. Thyroïde USPSTF 1996 Routine screening for thyroid cancer using neck palpation or ultrasonography is not recommended for asymptomatic children or adults.(Recommandation D) Guide de l’examen médical périodique – révision janvier 2010 | 27 There is insufficient evidence to recommend for or against screening persons with a history of external head and neck irradiation in infancy or childhood, but recommendations for such screening may be made on other grounds.(Recommandation C) 28 | Umf de Gatineau MALADIES INFECTIEUSES ITSS (Counselling) ÉTATS-UNIS USPSTF 2008 The USPSTF recommends high-intensity behavioral counseling to prevent sexually transmitted infections (STIs) for all sexually active adolescents and for adults at increased risk for STIs. (Recommandation B) The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of behavioral counseling to prevent STIs in non-sexually-active adolescents and in adults not at increased risk for STIs. (Recommandation I) Risk assessment: All sexually active adolescents are at increased risk for STIs and should be offered counseling. Adults with current STIs or infections within the past year are at increased risk for future STIs. In addition, adults who have multiple current sexual partners should be considered at increased risk and offered counseling to prevent STIs. Married adolescents may be considered for counseling if they meet the criteria described for adults. Clinicians should also consider the communities they serve. If the practice's population has a high rate of STIs, all sexually active patients in nonmonogamous relationships may be considered to be at increased risk. Among the studies reviewed, successful high-intensity interventions were delivered through multiple sessions, most often in groups, with total durations from 3 to 9 hours. Little evidence suggests that single-session interventions or interventions lasting less than 30 minutes were effective in reducing STIs. CANADA Chlamydia 1) CTFPHC 1996 Fair evidence to support annual screening of high-risk groups (Recommandation B) (*High-risk groups are sexually active women less than 25 years of age, women with new sexual partners, women or men with multiple sexual partners during the previous year, women who use nonbarrier contraceptive methods and women who have symptoms of chlamydial infection (cervical friability, mucopurulent cervical discharge or intermenstrual bleeding).) Fair evidence to exclude routine screening of the general population (Recommandation D) 2) Lignes directrices canadiennes sur le ITSS 2006 Personne les plus touchées : jeunes femmes agées de 15 à 24 ans, jeunes hommes agés de 20 à 29 ans Facteurs de risque : un contact sexuel ave une personne infectée, un nouveau partenaire sexuel ou plus de deux partenaires sexuel au cours de l’années précédente, des antécédents d’ITSS, les Guide de l’examen médical périodique – révision janvier 2010 | 29 populations vulnérables, comme les utilisateurs de drogues injectables, incarcérées, les travailleurs de l’industrie du sexe et les jeunes de la rue. les personnes 3) Guide québecois de dépistage des ITSS 2006 Depistage pour la ▪personne de 25 ans et moins ayant eu un nouveau partenaire sexuel, sans autre facteur de risque ▪personne de 25 ans et moins ayant eu deux partenaires sexuels durant la dernière année ▪personne de 25 ans ou moins ayant contracté une ITSS au cours de l’année précédente ▪ femme demandant une interuuption de grosesse ▪personne ayant eu plus de deux partenaires sexuels au cours des deux derniers mois ou plus de cinq partenaires au cours de la dernière année ▪jeune de la rue ▪utilisateur de drogue, par injection ou non ▪homme ayant des relations sexuelles avec d’autres hommes ▪personne ayant eu une relation sexuelle avec un nouveau partenaire revenant d’un séjour dans une région où les ITS ou le VIH sont endémiques ▪personne ayant eu une relation sexuelle avec un partenaire originaire d’un pays où les ITS ou le VIH sont endémiques ▪travailleur(se) du sexe ▪personne demandant un dépisatge, même en l’absence de facteur de risque avoué après un counselling pré-test ▪femme enceinte Dépistage à envisager : ▪nouveau-né dont l’un des parents a une ITSS ou est à risque (*voir tableau en annexe ou http://www.masexualite.ca/professionnels/its-4.aspx ) ÉTATS-UNIS 1) USPSTF 2007 The U.S. Preventive Services Task Force (USPSTF) recommends screening for chlamydial infection for all sexually active non-pregnant young women aged 24 and younger and for older non-pregnant women who are at increased risk . (Recommandation A)The USPSTF recommends screening for chlamydial infection for all pregnant women aged 24 and younger and for older pregnant women who are at increased risk . (Recommandation B) Intervalle : Screening for pregnant women who are at increased risk for chlamydial infection is recommended at the first prenatal visit. For pregnant women who remain at increased risk and for those who acquire a new risk factor, such as a new sexual partner, a screening should be conducted during the third trimester. The optimal interval for screening for nonpregnant women is unknown. The CDC recommends at least annual screening for women at increased risk Risque accru: All sexually active women 24 years of age or younger, including adolescents, are at increased risk for chlamydial infection. In addition to sexual activity and age, other risk factors for chlamydial infection include a history of chlamydial or other sexually transmitted infection, new or multiple sexual partners, inconsistent condom use, and exchanging sex for money or drugs. Risk factors for pregnant women are the same as for nonpregnant women. The USPSTF recommends against routinely providing screening for chlamydial infection for women aged 25 and older, whether or not they are pregnant, if they are not at increased risk . (Recommandation C) The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for chlamydial infection for men . (Recommandation I) 30 | Umf de Gatineau 2) ACPM 2003 Assessment of risk factors for infection with Chlamydia trachomatis should be performed during every routine healthcare contact of sexually active women. Sexually active women with risk factors should be screened annually. Risk factors include age < 25 years, a new male sex partner or two or more partners during the preceding year, inconsistent use of barrier contraception, history of a prior STD, African-american race and cervival ectopy. All partners of women with positive test should be tested for chlamydia. Gonorrhée CANADA 1) CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Gonorrhee : Fair evidence to provide counselling to prevent spread of gonorrhea. (Recommandation B) good evidence to screen those at high-risk.* (Recommandation A) *High-risk groups include: individuals under age 30 years with at least 2 sexual partners in the previous year or age 16 years at first intercourse, prostitutes, sexual contacts of individuals known to have a sexually transmitted disease. 2) Lignes directrices canadiennes sur les ITSS 2006 Personnes les plus touchées : jeunes hommes agés de 20 à 29 ans (les hommes représentent 2/3 des cas signalés, augmentation Chez les HARSAH), jeunes femmes agées de 15 à 24 ans. Facteurs de risque : les individus ayant des contacts avec une personne atteinte d’une infection confirmée ou d’un syndrome compatible, les individus qui ont eu des relations sexuelles non protégées avec une personne provenant d’une région du monde où la maladie est endémique (il existe également un risque de résistance plus élevé chez la population de ces régions), les voyageurs qui séjournent dans des régions du monde où la maladie est endémique et qui ont des rapports sexuels non protégés avec une personne habitant une telle région (il existe également un risque de résistance plus élevé chez la population de ces régions), les travailleurs de l’industrie du sexe et leurs partenaires sexuels, les jeunes âgés de moins de 25 ans, actifs sexuellement et ayant plusieurs partenaires, les jeunes de la rue, les hommes ayant des relations sexuelles non protégées avec d’autres hommes, les personnes ayant des antécédents de gonorrhée et d’autres ITS.Dans une étude passive de surveillance canadienne, la réinfection a été rapportée d’être au moins 2% par année 3) Guide québecois de dépisatge des ITSS 2006 Dépistage pour ▪personne ayant eu plus de deux partenaires sexuels au cours des deux derniers mois ou plus de cinq partenaires au cours de la dernière année ▪jeune de la rue ▪utilisateur de drogue, par injection ou non ▪homme ayant des relations sexuelles avec d’autres hommes ▪personne ayant eu une relation sexuelle avec un nouveau partenaire revenant d’un séjour dans une région où les ITS ou le VIH sont endémiques ▪personne ayant eu une relation sexuelle avec un partenaire originaire d’un pays où les ITS ou le VIH sont endémiques ▪travailleur(se) du sexe Guide de l’examen médical périodique – révision janvier 2010 | 31 ▪personne demandant un dépisatge, même en l’absence de facteur de risque avoué après un counselling pré-test ▪femme enceinte. Dépistage à envisager : ▪personne de 25 ans et moins ayant eu deux partenaires sexuels durant la dernière année ▪personne de 25 ans ou moins ayant contracté une ITSS au cours de l’année précédente ▪ femme demandant une interuuption de grosesse ▪nouveau-né dont l’un des parents a une ITSS ou est à risque. (*voir tableau en annexe ou http://www.masexualite.ca/professionnels/its-4.aspx ). ÉTATS-UNIS USPSTF 1996 Routine screening for Neisseria gonorrhoeae is recommended for: Asymptomatic women at high risk of infection. (Recommandation B) High-risk groups include commercial sex workers, persons with a history of repeated episodes of gonorrhea and young women(under age 25) with two or more sex partners in the last year.(actual risk depends on local epidemiology). Syphilis CANADA 1) Lignes directrices canadiennes sur les ITSS 2006 Personnes les plus touchées : HARSAH (VIH+ et VIH-) âgés de 30 à 39 ans, Travailleurs de l’industrie du sexe et leurs clients, Acquisition dans les régions endémiques 2) Guide québecois de dépisatge des ITSS 2006 Dépistage pour ▪personne ayant eu plus de deux partenaires sexuels au cours des deux derniers mois ou plus de cinq partenaires au cours de la dernière année ▪jeune de la rue ▪utilisateur de drogue, par injection ou non ▪homme ayant des relations sexuelles avec d’autres hommes ▪personne ayant eu une relation sexuelle avec un nouveau partenaire revenant d’un séjour dans une région où les ITS ou le VIH sont endémiques ▪personne ayant eu une relation sexuelle avec un partenaire originaire d’un pays où les ITS ou le VIH sont endémiques ▪travailleur(se) du sexe ▪personne demandant un dépistage, même en l’absence de facteur de risque avoué après un counselling pré-test ▪femme enceinte. Dépistage à envisager : ▪personne de 25 ans et moins ayant eu deux partenaires sexuels durant la dernière année ▪personne de 25 ans ou moins ayant contracté une ITSS au cours de l’année précédente ▪ femme demandant une interruption de grossesse ▪nouveau-né dont l’un des parents a une ITSS ou est à risque (*voir tableau en annexe ou http://www.masexualite.ca/professionnels/its-4.aspx) 32 | Umf de Gatineau ÉTATS-UNIS USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) strongly recommends that clinicians screen persons at increased risk for syphilis infection. (Recommendation A) Populations at increased risk for syphilis infection (as determined by incident rates) include men who have sex with men and engage in high-risk sexual behavior, commercial sex workers, persons who exchange sex for drugs, and those in adult correctional facilities. There is no evidence to support an optimal screening frequency in this population. Persons diagnosed with other sexually transmitted diseases (STDs) (i.e., chlamydia, gonorrhoea, genital herpes simplex, human papilloma virus, and HIV) may be more likely than others to engage in high-risk behavior, placing them at increased risk for syphilis; however, there is no evidence that supports the routine screening of individuals diagnosed with other STDs for syphilis infection. Clinicians should use clinical judgment to individualize screening for syphilis infection based on local prevalence and other risk factors. HIV CANADA 1) CTFPHC 1991 (recommandation qui date de PLUS DE 15 ANS) Voluntary HIV testing : Good evidence to include offer of screening in PHE of asymptomatic people at high risk. (Recommandation A) 2) Lignes directrices canadiennes sur les ITSS 2006 Personnes les plus touchées : HARSAH, Acquisition dans les régions endémiques, Utilisateurs de drogues injectables, Jeunes femmes âgées de 15 à 19 ans 3) Guide québécois de dépistage des ITSS 2006 Dépistage pour ▪personne ayant eu plus de deux partenaires sexuels au cours des deux derniers mois ou plus de cinq partenaires au cours de la dernière année ▪jeune de la rue ▪utilisateur de drogue, par injection ou non ▪homme ayant des relations sexuelles avec d’autres hommes ▪personne ayant eu une relation sexuelle avec un nouveau partenaire revenant d’un séjour dans une région où les ITS ou le VIH sont endémiques ▪personne ayant eu une relation sexuelle avec un partenaire originaire d’un pays où les ITS ou le VIH sont endémiques ▪travailleur(se) du sexe ▪personne demandant un dépistage, même en l’absence de facteur de risque avoué après un counselling pré-test ▪femme enceinte ▪possibilité d’exposition sanguine accidentelle (tatouage ou perçage dans des conditions non-steriles, exposition en milieu de travail) ▪transfusion de sang ou de produits sanguins, greffe de tissus ou d’organe Dépistage à envisager : ▪personne de 25 ans et moins ayant eu deux partenaires sexuels durant la dernière année ▪personne de 25 ans ou moins ayant contracté une ITSS au cours de l’année précédente ▪ femme demandant une interruption de grosesse ▪nouveau-né dont l’un des parents a une ITSS ou est à risque (*voir tableau en annexe ou http://www.masexualite.ca/professionnels/its-4.aspx) Guide de l’examen médical périodique – révision janvier 2010 | 33 ÉTATS-UNIS USPSTF 2005 The U.S. Preventive Services Task Force (USPSTF) strongly recommends that clinicians screen for human immunodeficiency virus all adolescents and adults at increased risk for HIV infection (Recommandation A) The USPSTF makes no recommendation for or against routinely screening for HIV adolescents and adults who are not at increased risk for HIV infection (Recommandation C) The USPSTF recommends that clinicians screen all pregnant women for HIV (Recommandation A) Risk factors : men who have had sex with men after 1975; men and women having unprotected sex with multiple partners; past or present injection drug users; men and women who exchange sex for money or drugs or have sex partners who do; individuals whose past or present sex partners were HIV-infected, bisexual, or injection drug users; persons being treated for sexually transmitted diseases (STDs); and persons with a history of blood transfusion between 1978 and 1985,persons who request an HIV test despite reporting no individual risk factors, persons who report no individual risk factors but are seen in high-risk or high-prevalence clinical settings. High-risk settings include STD clinics, correctional facilities, homeless shelters, tuberculosis clinics, clinics serving men who have sex with men, and adolescent health clinics. Hépatites CANADA HEPATITE B 1) Lignes directrices canadiennes sur les ITSS 2006 Personne les plus touchées : Nourrissons dont la mère est positive pour l’antigène HBs, Utilisateurs de drogues injectables qui partagent leur matériel, Personnes ayant plusieurs partenaires sexuels, Acquisition dans les régions endémiques , Contacts sexuels ou personnes vivant sous le même toit d’un cas aigus ou chronique 2) Guide québecois de dépistage des ITSS 2006 Dépistage pour ▪personne ayant eu plus de deux partenaires sexuels au cours des deux derniers mois ou plus de cinq partenaires au cours de la dernière année ▪jeune de la rue ▪utilisateur de drogue, par injection ou non ▪homme ayant des relations sexuelles avec d’autres hommes ▪personne ayant eu une relation sexuelle avec un nouveau partenaire revenant d’un séjour dans une région où les ITS ou le VIH sont endémiques ▪personne ayant eu une relation sexuelle avec un partenaire originaire d’un pays où les ITS ou le VIH sont endémiques ▪travailleur (se) du sexe ▪personne demandant un dépistage, même en l’absence de facteur de risque avoué après un counselling pré-test ▪femme enceinte ▪possibilité d’exposition sanguine accidentelle (tatouage ou perçage dans des conditions non-steriles, exposition en milieu de travail) ▪transfusion de sang ou de produits sanguins, greffe de tissus ou d’organe Dépistage à envisager : ▪personne de 25 ans et moins ayant eu deux partenaires sexuels durant la dernière année ▪personne de 25 ans ou moins ayant contracté une ITSS au cours de l’année précédente ▪ femme demandant une 34 | Umf de Gatineau interruption de grossesse ▪nouveau-né dont l’un des parents a une ITSS ou est à risque (*voir tableau en annexe ou http://www.masexualite.ca/professionnels/its-4.aspx) HEPATITE C Guide québécois de dépistage des ITSS 2006 Dépistage pour : ▪utilisateur de drogue, par injection ou non ▪possibilité d’exposition sanguine accidentelle (tatouage ou perçage dans des conditions non-steriles, exposition en milieu de travail) ▪transfusion de sang ou de produits sanguins, greffe de tissus ou d’organe ▪personne demandant un dépistage, même en l’absence de facteur de risque avoué après un counselling prétest Dépistage à envisager : pour ▪personne ayant eu plus de deux partenaires sexuels au cours des deux derniers mois ou plus de cinq partenaires au cours de la dernière année ▪personne de 25 ans ou moins ayant contracté une ITSS au cours de l’année précédente ▪homme ayant des relations sexuelles avec d’autres hommes ▪femme enceinte ▪nouveau-né dont l’un des parents a une ITSS ou est à risque (*voir tableau en annexe ou http://www.masexualite.ca/professionnels/its-4.aspx) ÉTATS-UNIS USPSTF 2004 Recommends against routinely screening the general asymptomatic population for chronic hepatitis B virus infection (Recommandation D) Recommends against routine screening for hepatitis C virus (HCV) infection in asymptomatic adults who are not at increased risk (general population) for infection. (Recommandation D) Insufficient evidence to recommend for or against routine screening for HCV infection in adults at high risk for infection (Recommandation I) Herpes Lignes directrices canadiennes sur les ITSS 2006 Personnes les plus touchées: Très fréquent chez les adolescents et les adultes, hommes ou femmes, Les femmes sont plus touchées que les hommes USPSTF 2005 Recommends against routine serological screening for HSV in asymptomatic adolescents and adults (Recommandation D) Guide de l’examen médical périodique – révision janvier 2010 | 35 Human papilloma virus infection Lignes directrices canadiennes sur les ITSS 2006 Personnes les plus touchées : Hommes et femmes, adolescents ou jeunes adultes (il frappe aussi bien les hommes que les femmes, et ce, quel que soit leur âge). CTFPHC 1995 HPV screening (beyond Papanicolaou testing for cervical cancer) : Fair evidence to exclude from periodic health examination. (Recommandation D) Rubéole CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Screening for immunization status (serology or proof of vaccination) and immunization of women at risk. Fair evidence to include in the periodic health examination of women of childbearing age. (Recommandation B) USPSTF 1996 Routine screening for rubella susceptibility by history of vaccination or by serology is recommended for all women of childbearing age at their first clinical encounter.(Recommandation B) Susceptible nonpregnant women should be offered rubella vaccination; susceptible pregnant women should be vaccinated immediately after delivery. (Recommandation B) Tuberculose CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Tuberculose : Good evidence to support screening individuals at high-risk* (Recommandation A) Good evidence to recommend INH prophylaxis to household contacts and skin test converters and persons with underlying medical conditions like HIV that increase the risk of reactivation of infection (Recommandation A); *High-risk groups include immigrants from endemic areas (Africa, Asia, Central America and certain countries in South America and the Caribbean), Canadian-born aboriginals, close contacts of active cases, persons with abnormal chest radiographs consistent with healed tuberculosis, and persons with underlying medical conditions which increase their likelihood of reactivation of 36 | Umf de Gatineau tuberculosis if infected (those with silicosis, jejunoilial by-pass, hemodialysis, gastrectomy, malnutrition, intravenous drug users, alcohol abusers and especially those with known or suspected infection with HIV). USPSTF 1996 Screening for tuberculous infection with tuberculin skin testing is recommended for all persons at increased risk of developping tuberculosis (Recommandation A) Persons infected with HIV, close contacts of personswith known or suspected TB, persons with medical risk factors associated with TB, immigrants from countries with high TB prevalence, medically underserved low-income populations, alcoholics, injection drug users, residents of long-term care facility. Bactériurie USPSTF 2008 The USPSTF recommends against screening for asymptomatic bacteriuria in men and nonpregnant women. (Recommandation D) Varicelle CTFPHC 2001 Immunization of susceptible adolescents and adults with varicella vaccine is effective in preventing varicella infection and secondary cases in household contacts (Recommandation B) Guide de l’examen médical périodique – révision janvier 2010 | 37 38 | Umf de Gatineau HABITUDES DE VIE Tabac CTFPHC 1994 Good evidence to support smoking cessation counselling (Recommandation A); nicotine replacement therapy may be offered as an adjunct. (Recommandation A) USPSTF 2009 The USPSTF recommends that clinicians ask all adults about tobacco use and provide tobacco cessation interventions for those who use tobacco products. (Recommandation A) AAFP has same recommandation Alcool CTFPHC 1994 Fair evidence to include routine detection and counselling in periodic health examination. (Recommandation B) by standardized questionnaire and/or patient inquiry USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) recommends screening and behavioral counselling interventions to reduce alcohol misuse by adults, including pregnant women, in primary care settings. (Recommandation B) the evidence is insufficient to recommend for or against screening and behavioral counselling interventions to prevent or reduce alcohol misuse by adolescents in primary care settings. (Recommandation I) Activité physique CANADA CTFPHC 1994 Evidence for or against a recommendation to include physical activity counselling in the PHE is lacking. (Recommandation C) There is fair evidence to recommend that individuals engage in the regular practice of moderate intensity physical activity. (Recommandation B) There is good evidence to recommend lifestyle interventions for overweight individuals (body mass index > 25 kg/m2, or > 22 kg/m2 if of Asian descent) with impaired glucose tolerance to reduce the incidence of progression to diabetes (Recommendation B). ÉTATS-UNIS USPSTF 2002 The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to recommend for or against behavioral counselling in primary care settings to promote physical activity. (Recommandation I) Guide de l’examen médical périodique – révision janvier 2010 | 39 AAFP The AAFP recognizes that regular physical activity is desirable. The effectiveness of physician's advice and counselling in this area is uncertain. Diète CTFPHC 1994 Fair evidence to provide general dietary advice (Recommandation B) There is good evidence to recommend lifestyle interventions for overweight individuals (body mass index > 25 kg/m2, or > 22 kg/m2 if of Asian descent) with impaired glucose tolerance to reduce the incidence of progression to diabetes (Recommandation B) USPSTF 2003 The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to recommend for or against routine behavioral counselling to promote a healthy diet in unselected patients in primary care settings. (Recommandation I). The USPSTF recommends intensive behavioral dietary counselling for adult patients with hyperlipidemia and other known risk factors for cardiovascular and diet-related chronic disease. Intensive counselling can be delivered by primary care clinicians or by referral to other specialists, such as nutritionists or dietitians (Recommandation B) Obésité CANADA CTFPHC 1998 Because of lack of evidence supporting long-term effectiveness of weight-reduction interventions, there is insufficient evidence to recommend for or against BMI measurement in the periodic health examination of the general population (Recommandation C ) There is fair evidence to recommend BMI measurement in the periodic health examination of obese adults with obesity-related disease (Recommandation B ) There is insufficient evidence to recommend for or against weight-reduction therapy in obese adults without obesity-related disease (Recommandation C ) There is fair evidence to recommend weight-reduction therapy in obese adults with obesityrelated disease (Recommandation B) CTFPHC 2005 There is good evidence to recommend lifestyle interventions for overweight individuals (body mass index > 25 kg/m2, or > 22 kg/m2 if of Asian descent) with impaired glucose tolerance to reduce the incidence of progression to diabetes (Recommandation B) There is fair evidence to recommend acarbose treatment for overweight individuals (as described above) with impaired glucose tolerance to prevent cardiovascular events and hypertension (Recommandation B). There is insufficient evidence to recommend metformin or acarbose treatment for overweight individuals (as described above) with impaired glucose tolerance to prevent diabetes progression (Recommandation I) 40 | Umf de Gatineau ÉTATS-UNIS USPSTF 2005 The evidence is insufficient to recommend for or against routine screening for overweight in children and adolescents as a means to prevent adverse health outcomes(Recommandation I) The USPSTF recommends that clinicians screen all adult patients for obesity USPSTF 2003 and offer intensive counselling and behavioral interventions to promote sustained weight loss for obese adults.(Recommandation B) The AAFP recommends screening for obesity by measuring height and weight AAFP periodically for all patients Guide de l’examen médical périodique – révision janvier 2010 | 41 42 | Umf de Gatineau PRÉVENTION DES ACCIDENTS CTFPHC 1993 Individual counselling for : Don’t drink and drive (Grade C) Use helmets when riding bicycles on roadway (Grade C) In the home, make guns inaccessible ; keep ammunition and gun separately (GradeC) Use of seatbelt and/or child restraints (Grade B ) Use of helmet when riding motorcycle or all-terrain vehicles (Grade C) In elderly Monitor elderly patients for medical impairment (balance, medication, gait abnormalities) (Grade C) Counselling regarding use of safety aid in hazardous areas such as stairs, bathtubs (Grade C) USPSTF 2007: The USPSTF concludes that the current evidence is insufficient to assess the incremental benefit, beyond the efficacy of legislation and community-based interventions, of counseling in the primary care setting, in improving rates of proper use of motor vehicle occupant restraints (child safety seats, booster seats, and lap-and-shoulder belts). (Recommandation I) 1996: Periodic counselling of the parents of children on measures to reduce the risk of unintentional household and recreational injuries is recommended. (Grade B) ; Measures to reduce the risk of unintentional injuries from residential fires and hot tap water, drowning, poisoning, bicycling, firearms and falls is recommended Counselling to prevent household and recreational injuries is also recommended for adolescents and adults based on the proven efficacy of risk reduction, although the effectiveness of counselling these patients to prevent injuries has not been adequately evaluated. (Grade C) Persons with alcohol or drug problems should be identified, counselled and monitored. Those who use alcohol or illicit drugs should be warned against engaging in potentially dangerous activities while intoxicated.(Grade B) Counselling elderly patients on specific measures to prevent falls is recommended based on fair evidence that these measures reduce the risk of falls (Grade B) although the effectiveness of counselling elders to prevent falls has not been adequately evaluated. (Grade C) More intensive individualized multi-factorial intervention is recommended for high-risk elderly patients in settings where adequate resources to deliver such services are available.(Grade B) There is insufficient evidence to recommend for or against the use of external hip protectors to prevent fall injuries. The following counselling to all patients, and the parents of young patients, is recommended: • Use occupant restraints (lap/shoulder safety belts and child safety seats). (Grade B) • Wear helmets when riding motorcycles. (Grade C) • Refrain from driving while under the influence of alcohol or other drugs (Grade C) There is currently insufficient evidence to recommend for or against counselling to prevent pedestrian injuries (Grade C) Guide de l’examen médical périodique – révision janvier 2010 | 43 AAFP The AAFP recommends counselling all parents and patients more than 2 years old regarding accidental injury prevention including, as appropriate: child safety seats lap and shoulder belt use, bicycle safety, motorcycle helmet use, smoke detectors, poison control center number, and driving while intoxicated. Personnes âgées American geriatrics society 2001 Routine Care of Older Persons (not presenting after a fall) • Clinicians caring for older persons should ask about fall history annually • Those patients who report a single fall should undergo a balance and gait screening. This is done by observing the ability to stand up from a chair without using arms, walk several paces and return. ( i.e. the "get up and go test") • Those having difficulty require further assessment and appropriate intervention such as referral to physical and or occupational therapy. Evaluation of Older Persons Presenting with One or More Falls or Having Abnormalities Gait and or Balance or who report Recurrent Falls: • History of the fall circumstances, medications (prescribed and over the counter), acute or chronic medical problems, and mobility levels • An examination of vision, muscle strength, gait, balance, and neurological function including lower extremity peripheral nerves, proprioception, reflexes,cortical and extrapyramidal and cerebellar functions should be done. An assessment of cognitive function and a basic cardiovascular evaluation including heart rate and rhythm, orthostatic pulse and blood pressure should be done., Single interventions: • Exercise: • • • • • • • • • • • • Although exercise has many proven benefits, the optimum type, duration and intensity to prevent falls remains unclear (B). Physical therapy, exercise and balance training should be offered to older persons who have recurrent falls (B). Tai Chi C'uan is said to improve balance, it requires further evaluation before before it can be recommended (C). Environmental Modification: Older persons at increased risk for falls should have an environmental assessment done of their home by an OT or other qualified professional (B). Medications: Patients, who have fallen, should have their medications reviewed especially those on more than four prescribed meds or those taking psychotropic meds (C). (There is no clear difference in risk for falls between long term and short-term benzodiazepines). Assistive devices: There is no clear evidence that use of assistive devices alone such as bed alarms, canes, and walkers have demonstrated benefits in preventing falls. While assistive devices may be effective elements of a multifactorial intervention program, their isolated use without attention to other risk factors cannot be recommended (C). Hip protectors do not appear to reduce the risk of falls (Class I), but have been shown to be effective in preventing fractures in high-risk individuals. Behavioral and Educational Programs: When used as an isolated intervention, health and behavioral education does not reduce falls (B). 44 | Umf de Gatineau Other Potential Interventions: • Visual/sensory loss: deficits in sight and sensation have been linked to a higher incidence of falls resulting in hip fractures. Identification of these deficits and appropriate intervention may be preventative. • Footwear interventions: there are no experimental studies of footwear examining falls as an outcome. There are, however trials looking at intermediate outcomes such as balance and sway from specific footwear interventions. For women, use of walking shoes was better than barefoot. For men, stability was best with high mid-sole hardness and low mid-sole thickness. MCAS Aspirine prévention primaire CTFPHC 1994 (recommandation qui date de PLUS DE 15 ANS) Weak evidence to use or not to use routine ASA therapy for the primary prevention of cardiovascular disease in asymptomatic men and women (Recommandation C) USPSTF 2009 The USPSTF recommends the use of aspirin for men age 45 to 79 years when the potential benefit due to a reduction in myocardial infarctions outweighs the potential harm due to an increase in gastrointestinal hemorrhage. (Recommandation A) Decisions about aspirin therapy should consider the overall risks for coronary heart disease and gastrointestinal bleeding. Available tools provide estimations of coronary heart disease risk (such as the calculator available at http://hp2010.nhlbihin.net/atpiii/calculator.asp). Estimated myocardial infarctions (MIs) prevented and estimated harms of using aspirin for 10 years in a hypothetical cohort of 1000 men http://www.ahrq.gov/clinic/uspstf09/aspirincvd/aspcvdrsf2.htm The USPSTF recommends the use of aspirin for women age 55 to 79 years when the potential benefit of a reduction in ischemic strokes outweighs the potential harm of an increase in gastrointestinal hemorrhage. (Recommandation A) Decisions about aspirin therapy should consider the overall risk for stroke and gastrointestinal bleeding. Tools for estimation of stroke risk are available (such as the calculator available at http://www.westernstroke.org/PersonalStrokeRisk1.xls). Estimated number of strokes prevented and estimated harms of using aspirin for 10 years in a hypothetical cohort of 1000 women on the basis of age and 10-year stroke risk. http://www.ahrq.gov/clinic/uspstf09/aspirincvd/aspcvdrsf4.htm Guide de l’examen médical périodique – révision janvier 2010 | 45 The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of aspirin for cardiovascular disease prevention in men and women 80 years or older. (Recommandation I) The net benefit of aspirin use in persons older than 80 years is probably best in those without risk factors for gastrointestinal bleeding (other than older age) and in those who could tolerate a gastrointestinal bleeding episode (for example, those with normal hemoglobin levels, good kidney function, and easy access to emergency care). The USPSTF recommends against the use of aspirin for stroke prevention in women younger than 55 years and for myocardial infarction prevention in men younger than 45 years. (Recommandation D) The optimum dose of aspirin for preventing cardiovascular disease events is not known. Primary prevention trials have demonstrated benefits with various regimens, including dosages of 75 and 100 mg/d and 100 and 325 mg every other day. A dosage of approximately 75 mg/d seems as effective as higher dosages. The risk for gastrointestinal bleeding may increase with dose. Aspirine prévention secondaire Diabètes Association canadienne du diabètes 2003 Unless contraindicated, low-dose ASA therapy (80 to 325 mg/day) is recommended in all patients with diabetes with evidence of CVD, as well as for those individuals with atherosclerotic risk factors that increase their likelihood of CV events (Grade A) American diabetes association 2009 In patients with known CVA aspirin (if nor contraindicated) should be used to reduce the risk of cardiovascular events (Grade A) Use aspirin therapy (75–162 mg/day) as a primary prevention strategy in those with type 1 or type 2 diabetes at increased cardiovascular risk , including those who are > 40 years of age or who have additional risk factors (family history of CVD, hypertension, smoking, dyslipidemia, or albuminuria (Grade C) Aspirin therapy is not recommended in people under 30 years of age and is contraindicated in people under the age of 21. (Grade E). 46 | Umf de Gatineau Hypertension Canadian hypertension society 2009 Strong consideration should be given to the addition of low dose ASA therapy in hypertensive patients (Grade A in patients older than 50 years). Caution should be exercised if blood pressure is not controlled (Grade C). Cochrane 2004 For primary prevention in patients with elevated blood pressure, anti-platelet therapy with ASA cannot be recommended since the magnitude of benefit, a reduction in myocardial infarction, is negated by a harm of similar magnitude, an increase in major haemorrhage. For secondary prevention in patients with elevated blood pressure (ATC meta-analysis: APTC 1994) antiplatelet therapy is recommended because the magnitude of the absolute benefit is many times greater. Warfarin therapy alone or in combination with aspirin in patients with elevated blood pressure cannot be recommended because of lack of demonstrated benefit. Glycoprotein IIb/IIIa inhibitors as well as ticlopidine and clopidogrel have not been sufficiently evaluated in patients with elevated blood pressure. Further trials of antithrombotic therapy with complete documentation of all benefits and harms are required in patients with elevated blood pressure. Guide de l’examen médical périodique – révision janvier 2010 | 47 Dépistage MCAS USPSTF 2004 The U.S. Preventive Services Task Force (USPSTF) recommends against routine screening with resting electrocardiography (ECG), exercise treadmill test (ETT), or electron-beam computerized tomography (EBCT) scanning for coronary calcium for either the presence of severe coronary artery stenosis (CAS) or the prediction of coronary heart disease (CHD) events in adults at low risk for CHD events. (Recommandation D) The USPSTF found insufficient evidence to recommend for or against routine screening with ECG, ETT, or EBCT scanning for coronary calcium for either the presence of severe CAS or the prediction of CHD events in adults at increased risk for CHD events. (Recommandation I) USPSTF 2009 The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to assess the balance of benefits and harms of using the nontraditional risk factors discussed in this statement to screen asymptomatic men and women with no history of CHD to prevent CHD events (Recommandation I) The nontraditional risk factors included in this recommendation are high-sensitivity C-reactive protein (hs-CRP), ankle–brachial index (ABI), leukocyte count, fasting blood glucose level, periodontal disease, carotid intima–media thickness (carotid IMT), coronary artery calcification (CAC) score on electron-beam computed tomography (EBCT), homocysteine level, and lipoprotein(a) level. Vitamine E CTFPHC 2003 Primary prevention of CVD : The CTF concludes that there is insufficient evidence to recommend for or against the use of routine vitamin E supplementation for the primary prevention of CVD events in the general population and in male smokers ( Recommandation I). Secondary prevention of CVD in patients with established CVD or risk factors for CVD : The CTF concludes that there is good evidence to recommend against the use of vitamin E for the secondary prevention of CVD in patients with established CVD or risk factors for CVD (Recommandation D) 48 | Umf de Gatineau MALADIES VASCULAIRES Anévrysme de l’aorte abdominale CTFPHC 1994 Palpation abdominale ou échographie : Poor evidence to include or exclude in periodic health examination of asymptomatic individuals (Recommandation C) but screening may be considered for individuals at high risk. (males over the age of 60 who are smokers with hypertension, claudication, evidence of other vascular disease or a positive family history of AAA) La société canadienne de chirurgie vasculaire 2008 Recommande que les hommes agés de 65 à 75 ans soient soumis au dépistage de l’AAA dans un programme de dépistage universel. Que les personnes à risque élevé d’AAA soient soumises à un dépistage sélectif individuel, à savoir: a) les femmes de plus de 65 ans à risque élevé en raisons d’antécédents de tabagisme ou de maladie cérébrovasculaire ou d’une histoire familiale b) les hommes de moins de 65 ans dont l’histoire familiale révèle des cas d’AAA. USPSTF 2005 Recommends one-time screening for abdominal aortic aneurysm (AAA) by ultrasonography in men aged 65 to 75 who have ever smoked. (Recommandation B) Makes no recommendation for or against screening for AAA in men aged 65 to 75 who have never smoked. (Recommandation C) Recommends against routine screening for AAA in women (Recommandation D) Sténose carotidienne CTFPHC 1994 Neck auscultation : Fair evidence not to include in periodic health examination of asymptomatic individuals. (Recommandation D) USPSTF 2007 The U.S. Preventive Services Task Force (USPSTF) recommends against screening for asymptomatic carotid artery stenosis (CAS) in the general adult population. (Recommandation D) MVAS USPSTF 1996 Routine screening for peripheral arterial disease in asymptomatic persons is not recommended (Recommandation D) Clinicians should be alert to symptoms of peripheral arterial disease in persons at increased risk, and should evaluate patients who have clinical evidence of vascular disease. Guide de l’examen médical périodique – révision janvier 2010 | 49 TROUBLES DE LA VISION OU DE L’AUDITION Vision CTFPHC 1995 Snellen in elderly : Fair evidence to include in the periodic health examination (PHE) (Recommandation B) USPSTF 2009 The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for visual acuity for the improvement of outcomes in older adults. (Recommandation I) AAFP The AAFP recommends screening for visual difficulties in elderly adults by performing Snellen acuity testing. Glaucome CTFPHC 1995 Screening in elderly: (Recommandation C) Insufficient evidence to include in or exclude from the PHE USPSTF 2005 There is insufficient evidence to recommend for or against screening adults for glaucoma (Recommandation I) The uncertainty of the magnitude of benefit from early treatment and given the known harms of screening and early treatment, the USPSTF could not determine the balance between the benefits and harms of screening for glaucoma. AUTRES The American Academy of Ophthalmology 2006 recommended frequency of eye examinations for the general population, based on age and presence of risk factors for glaucomatous optic neuropathy. The TABLE 1 Recommended Frequency of Comprehensive Adult Medical Eye Evaluation Age (years) With Risk Factors for Glaucoma No Known Risk Factors >65 6-12 months[A:III] 1-2 years1 [A:II] 55-64 1-2 years[A:III] 1-3 years[A:III] [A:III] 40-54 1-3 years 2-4 years[A:III] [A:III] Under 40 2-4 years 5-10 years[A:III] The overall likelihood of developing glaucomatous optic neuropathy increases with the number and strength of risk factors, which include the following: Elevated IOP measurement, Older age, Family history of glaucoma, Thinner central corneal thickness, African or Hispanic/Latino descent, Increased cup-to-disc ratio. In addition, migraine headache and peripheral vasospasm have been identified in some studies as risk factors for progressing to glaucomatous optic nerve damage. The association between factors such as concurrent cardiovascular disease, systemic hypertension, and myopia and the development of glaucomatous optic nerve damage has not been demonstrated consistently. The relationship between diabetes mellitus and progression to glaucomatous optic neuropathy is unclear. 50 | Umf de Gatineau In 2007 they wrote: We are requesting a reevaluation of the USPSTF recommendation at this time, because of new evidence regarding screening for and treatment of glaucoma not available at the time of the USPSTF report and because of significant concerns regarding the scope and applicability of the USPSTF recommendation. Surdité CTFPHC 1994 Fair evidence to screen the elderly for hearing impairment. (Recommandation B) USPSTF 1996 Screening for older adults for hearing impairment is recommended through: • Periodically questioning them about their hearing. (Recommandation B) • Counselling them about the availability of hearing aid devices. • Making referrals for abnormalities when appropriate. There is insufficient evidence to recommend for or against routinely screening asymptomatic working-age adults for hearing impairment. Recommendations against such screening, except for those exposed to excessive occupational noise levels, may be made on other ground. SANTÉ MENTALE Drogues USPSTF 2008 The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening adolescents, adults, and pregnant women for illicit drug use (Recommandation I) Dépression in adults CTFPHC 2005 There is fair evidence to recommend screening adults in the general population for depression in primary care settings that have integrated programs for feedback to patients and access to case management or mental health care (Recommandation B) There is insufficient evidence to recommend for or against screening adults in the general population for depression in primary care settings where effective follow-up and treatment are not available (Recommandation I) Guide de l’examen médical périodique – révision janvier 2010 | 51 USPSTF-2009 The USPSTF recommends screening adults for depression when staff-assisted depression care supports are in place to assure accurate diagnosis, effective treatment, and follow-up. (Recommandation B). Asking 2 simple questions about mood and anhedonia ("Over the past 2 weeks, have you felt down, depressed, or hopeless?" and "Over the past 2 weeks, have you felt little interest or pleasure in doing things?") may be as effective as using more formal instruments. The optimum interval for screening for depression is unknown. Recurrent screening may be most productive in patients with a history of depression, unexplained somatic symptoms, comorbid psychological conditions (for example, panic disorder or generalized anxiety), substance abuse, or chronic pain. The USPTF recommends against routinely screening adults for depression when staff-assisted depression care supports are not in place. There may be considerations that support screening for depression in an individual patient. (Recommandation C) Dépression in adolescents USPSTF-2009 The USPSTF recommends screening of adolescents (12-18 years of age) for major depressive disorder (MDD) when systems are in place to ensure accurate diagnosis, psychotherapy (cognitive-behavioral or interpersonal), and follow-up. (Recommandation B) Démence CTFPHC 2001 There is insufficient evidence to recommend for, or against, screening for cognitive impairment in the absence of dementia, (Recommandation C) Memory complaints should be evaluated and the individual followed to assess progression (Recommandation B) When caregivers or informants describe cognitive decline in an individual, these observations should be taken very seriously: cognitive assessment and careful follow-up are indicated (Recommandation A) USPSTF 2003 The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to recommend for or against routine screening for dementia in older adults. (Recommandation I) 52 | Umf de Gatineau Violence familiale USPSTF 2004 insufficient evidence to recommend for or against routine screening of parents or guardians for the physical abuse or neglect of children, of women for intimate partner violence, or of older adults or their caregivers for elder abuse (Recommandation I) SOGC-2005 Les fournisseurs de soins de santé devraient inclure des questions au sujet de la violence dans le cadre de l’évaluation de la santé comportementale de leurs nouvelles patientes, à l’occasion des consultations préventives annuelles, dans le cadre des soins prénatals, ainsi qu’en réaction à des symptômes ou à des états pathologiques associés à la violence. (B) MALADIES CHRONIQUES MPOC USPSTF 2008 The USPSTF recommends against screening adults for chronic obstructive pulmonary disease (COPD) using spirometry (Recommandation D) Guide de l’examen médical périodique – révision janvier 2010 | 53 54 | Umf de Gatineau SANTÉ DE LA FEMME (divers) Contraception CTFPHC 1994 Physicians who see adolescents should advise those who are sexually active about the correct use of appropriate contraception (Recommandation B) (Révision en cours ) Oral contraceptive has been identified as the method of choice for adolescents in combination with a condom to protect against sexually transmitted diseases USPSTF 1996 Periodic counselling about effective contraceptive methods is recommended for all women and men at risk for unintended pregnancy. (Recommandation B) Counselling should be based on information from a careful sexual history and should take into account the individual preferences, abilities, and risks of each patient. Sexually active patients should also receive information on measures to prevent sexually transmitted diseases Acide folique en préconception CTFPHC 1994 Good evidence to advise all women capable of becoming pregnant to increase their consumption of folic acid to 0.4 mg/day. Supplementation appears to be the most effective and practical way to achieve this goal. (Recommandation A) USPSTF 2009 The USPSTF recommends that all women planning or capable of pregnancy take a daily supplement containing 0.4 to 0.8 mg (400 to 800 µg) of folic acid. (Recommandation A) Chimioprophylaxie contre le cancer du sein CTFPHC 2001 There is fair evidence to recommend counselling high risk women about the potential benefits and risks of using tamoxifen to reduce the likelihood of breast cancer, and hence support individual choice. (Recommandation B) (High Risk Women (e.g. 1.66% or more on Gail Index) Screening using the Gail Index has not been evaluated for general use National Cancer Institute: The model is applicable to women 40 years or older who receive regular mammography. (possible de calculer le risque à http://bcra.nci.nih.gov/brc/ ) USPSTF 2002 The USPSTF recommends that clinicians discuss chemoprevention with women at high risk for breast cancer and at low risk for adverse effects of chemoprevention. Clinicians should inform patients of the potential benefits and harms of chemoprevention(Recommandation B) Hormonothérapie CTFPHC 2004 Recommends against the use of combined estrogen-progestin therapy and estrogen-only therapy for the primary prevention of chronic disease in menopausal women (Recommandation D) For women who wish to alleviate menopausal symptoms using hormone replacement therapy (HRT), a discussion between the woman and her physician about the potential benefits and risks of HRT is warranted. (Voir aussi le site de la SOGC : www.sogc.org) USPSTF 2005 Guide de l’examen médical périodique – révision janvier 2010 | 55 The U.S. Preventive Services Task Force (USPSTF) recommends against the routine use of combined estrogen and progestin for the prevention of chronic conditions in postmenopausal women (Recommandation D) The USPSTF recommends against the routine use of unopposed estrogen for the prevention of chronic conditions in postmenopausal women who have had a hysterectomy (Recommandation D) (Voir aussi le site du WHI : www.whi.org) 56 | Umf de Gatineau Liste des sites web EMP général Canadian task force Site: http://www.ctfphc.org/ Livre de 1994: http://www.hc-sc.gc.ca/hppb/soinsdesante/pdf/soins98/s7c50f.pdf US task force http://www.ahrq.gov/clinic/uspstfix.htm American college of preventive medicine: http://www.acpm.org/pol_practice.htm Glycémie Association canadienne du diabète http://www.diabetes.ca/cpgfrancais/default.aspx American diabetes association http://care.diabetesjournals.org/content/vol29/suppl_1/ American association of clinical endocrinologists http://www.aace.com/pub/pdf/guidelines/DMGuidelines2007.pdf Cholestérol Canadian cardiovascular society http://www.ccs.ca/download/position_statements/lipids.pdf NCEPP III http://www.nhlbi.nih.gov/guidelines/cholesterol/ American heart association http://www.americanheart.org/presenter.jhtml?identifier=548 American association of clinical endocrinologists: http://www.aace.com/clin/guidelines/lipids.pdf Hypertension Canadian hypertension society www.hypertension.ca/chep/recommandations2006/CHEP_06_BookletFullText_vf.pdf Société québécoise d’hypertension artérielle http://www.hypertension.qc.ca/docs/guide_SQHTA_2002.pdf JNC 7 http://www.nhlbi.nih.gov/guidelines/hypertension/index.htm http://hyper.ahajournals.org/cgi/reprint/42/6/1206 Ostéoporose Osteoporosis society of Canada (guidelines 2002) http://www.cmaj.ca/content/vol167/10_suppl/index.shtml National osteoporosis foundation 2003 http://www.nof.org/physguide/table_of_contents.htm Cancer du sein Société canadienne du cancer http://www.cancer.ca/ccs/internet/standard/0,3182,3172_10175_74567690_langId-fr,00.html National cancer institute http://www.cancer.gov/newscenter/mammstatement31jan02 ACOG ACOG Practice Bulletin. Obstetrics and Gynecology. Avril 2003 vol 101 pp821-32 American geriatrics society http://www.americangeriatrics.org/education/cp_index.shtml Guide de l’examen médical périodique – révision janvier 2010 | 57 Cancer du côlon Canadian association of gastroenterologists http://www.cag-acg.org/guidelines/pdf/Colorectal%20cancer%20screening%202004.pdf National committee on colorectal cancer sreening http://www.hc-sc.gc.ca/pphb-dgspsp/publicat/ncccs-cndcc/pdf/ccstechrep_e.pdf American Gastroenterological Association http://www2.us.elsevierhealth.com/inst/serve?action=searchDB&searchDBfor=art&artType=abs &id=agast1240544&nav=abs&special=hilite&query=[articletitle](colorectal+cancer+screening,su rveillance,) Cancer du col utérin American cancer society http://www.cancer.org/docroot/PED/content/PED_2_3X_ACS_Cancer_Detection_Guidelines_36. asp?sitearea=PED ACOG (American college of obstetricians and gynecologists) ACOG Practice Bulletin. Obstetrics and Gynecology aout 2003 vol 102. pp417-27 American geriatrics society http://www.americangeriatrics.org/products/positionpapers/cer_carc_2000.shtml Cancer de la prostate Canadian urological association http://www.cua.org/ http://www.bccancer.bc.ca/HPI/CancerManagementGuidelines/Genitourinary/Prostate/PSAScre ening/PositionsofOtherMedicalOrganizationsonScreeningforProstateCancerwithPSA.htm American urological association http:www.urologyhealth.org/adult/index.cfm?cat=09&topic=250 http://www.bccancer.bc.ca/HPI/CancerManagementGuidelines/Genitourinary/Prostate/PSAScre ening/PositionsofOtherMedicalOrganizationsonScreeningforProstateCancerwithPSA.htm Prevention des accidents American geriatrics society http://www.americangeriatrics.org/products/positionpapers/abstract.shtml Maladies infectieuses Guide québecois de dépistage des ITSS 2006 http://www.masexualite.ca/professionnels/its-4.aspx Lignes directrices canadiennes pour les MTS 1998 http://www.phac-aspc.gc.ca/publicat/std-mts98/index_f.html 58 | Umf de Gatineau ANNEXE 1 Feuilles synthèse des recommandations Par sexe et groupe d’âge Les recommandations A ou B du Canada et/ou des Etats-Unis qui s’adressait à une population générale adulte ont été incluses. Toutefois si une recommandation d’un organisme autre semblait pertinente et importante la manœuvre a quand même été incluse dans la liste. Chaque item est suivi des recommandations canadienne et américaine. La première valeur est celle du CTFPHC. Elle est suivie de celle du USPSTF. Lorsque qu’il n’y a pas de recommandation un * apparaît. Pour les recommandations des autres associations se référer au document de base. Adolescent 20-35 ans 35-50 ans 50-70 ans > 70 ans Ces feuilles sont disponibles sur notre site : http://medecinefamiliale.com/umf/emp Guide de l’examen médical périodique – révision janvier 2010 | 59 60 | Umf de Gatineau ANNEXE 2 Suggestion de feuilles de prise de données pour l’examen périodique adolescent-adulte Adolescents 20-35 ans 35-50 ans 50-70 ans > 70 ans Ces feuilles sont disponibles sur notre site : http://medecinefamiliale.com/umf/emp Guide de l’examen médical périodique – révision janvier 2010 | 61 62 | Umf de Gatineau ANNEXE 3 Suggestion de feuilles sommaires Ces feuilles sont disponibles sur notre site : http://medecinefamiliale.com/umf/emp Guide de l’examen médical périodique – révision janvier 2010 | 63 64 | Umf de Gatineau ANNEXE 4 Critères pour les recommandations des divers groupes Guide de l’examen médical périodique – révision janvier 2010 | 65 66 | Umf de Gatineau Recommandations des différents groupes CTFPHC (Canadian Task force on preventive health care) Grade A: good evidence to recommend the clinical preventive action. Grade B: fair evidence to recommend the clinical preventive action. Grade C: the existing evidence is conflicting and does not allow making a recommendation for or against use of the clinical preventive action, however other factors may influence decision-making Grade D: fair evidence to recommend against the clinical preventive action. Grade E: good evidence to recommend against the clinical preventive action. Grade I: insufficient evidence (in quantity and/or quality) to make a recommendation, however other factors may influence decision-making I: Evidence from randomized controlled trial(s) II-1: Evidence from controlled trial(s) without randomization II-2: Evidence from cohort or case-control analytic studies, preferably from more than one centre or research group II-3: Evidence from comparisons between times or places with or without the intervention; dramatic results in uncontrolled experiments could be included here III: Opinions of respected authorities, based on clinical experience; descriptive studies or reports of expert committees USPSTF (US preventive services task force) A.— The USPSTF strongly recommends that clinicians provide [the service] to eligible patients. The USPSTF found good evidence that [the service] improves important health outcomes and concludes that benefits substantially outweigh harms. B.— The USPSTF recommends that clinicians provide [this service] to eligible patients. The USPSTF found at least fair evidence that [the service] improves important health outcomes and concludes that benefits outweigh harms. C.— The USPSTF makes no recommendation for or against routine provision of [the service]. The USPSTF found at least fair evidence that [the service] can improve health outcomes but concludes that the balance of benefits and harms is too close to justify a general recommendation. D.— The USPSTF recommends against routinely providing [the service] to asymptomatic patients. The USPSTF found at least fair evidence that [the service] is ineffective or that harms outweigh benefits. I.— The USPSTF concludes that the evidence is insufficient to recommend for or against routinely providing [the service]. Evidence that the [service] is effective is lacking, of poor quality, or conflicting and the balance of benefits and harms cannot be determined Guide de l’examen médical périodique – révision janvier 2010 | 67 American diabetes association A Clear evidence from well-conducted, generalizable, randomized controlled trials that are adequately powered, including: • Evidence from a well-conducted multicenter trial • Evidence from a meta-analysis that incorporated quality ratings in the analysis Compelling nonexperimental evidence, i.e., "all or none" rule developed by the Centre for Evidence-Based Medicine at Oxford Supportive evidence from well-conducted randomized controlled trials that are adequately powered, including: • Evidence from a well-conducted trial at one or more institutions • Evidence from a meta-analysis that incorporated quality ratings in the analysis B Supportive evidence from well-conducted cohort studies, including: • Evidence from a well-conducted prospective cohort study or registry • Evidence from a well-conducted meta-analysis of cohort studies Supportive evidence from a well-conducted case-control study C Supportive evidence from poorly controlled or uncontrolled studies, including: • Evidence from randomized clinical trials with one or more major or three or more minor methodological flaws that could invalidate the results • Evidence from observational studies with high potential for bias (such as case series with comparison with historical controls) • Evidence from case series or case reports Conflicting evidence with the weight of evidence supporting the recommendation E Expert consensus or clinical experience Association canadienne du diabète et La société de l’ostéoporose du Canada Catégorie A: Les meilleures données probantes étaient de niveau 1 Catégorie B : Les meilleures données probantes étaient de niveau 2 Catégorie C : Les meilleures données probantes étaient de niveau 3 Catégorie D : Les meilleures données probantes étaient de niveau 4 ou il y a eu consensus Pour le diagnostic Niveau 1 : études répondent à 5 critères prédéfinis sur 5 Niveau 2 : études répondent à 4 critères Niveau 3 : études répondent à 3 critères Niveau 4 : études répondent à 1 ou 2 critères 68 | Umf de Gatineau Recommandations des différents groupes SOGC Tableau 1 Critères d’évaluation des résultats et classification des recommandations Niveaux des résultats* Catégories de recommandations† I: Résultats obtenus dans le cadre d’au moins un essai comparatif convenablement randomisé. II-1: Résultats obtenus dans le cadre d’essais comparatifs non randomisés bien conçus. II-2: Résultats obtenus dans le cadre d’études de cohortes (prospectives ou rétrospectives) ou d’études analytiques cas-témoins bien conçues, réalisées de préférence dans plus d’un centre ou par plus d’un groupe de recherche. II-3: Résultats découlant de comparaisons entre différents moments ou différents lieux, ou selon qu’on a ou non recours à une intervention. Des résultats de première importance obtenus dans le cadre d’études non comparatives (par exemple, les résultats du traitement à la pénicilline, dans les années 1940) pourraient en outre figurer dans cette catégorie. III: Opinions exprimées par des sommités dans le domaine, fondées sur l’expérience clinique, études descriptives ou rapports de comités d’experts. A. On dispose de données suffisantes pour appuyer la recommandation selon laquelle il faudrait s’intéresser expressément à cette affection dans le cadre d’un examen médical périodique. B. On dispose de données acceptables pour appuyer la recommandation selon laquelle il faudrait s’intéresser expressément à cette affection dans le cadre d’un examen médical périodique. C. On dispose de données insuffisantes pour appuyer l’inclusion ou l’exclusion de cette affection dans le cadre d’un examen médical périodique, mais les recommandations peuvent reposer sur d’autres fondements. D. On dispose de données acceptables pour appuyer la recommandation de ne pas s’intéresser à cette affection dans le cadre d’un examen médical périodique. E. On dispose de données suffisantes pour appuyer la recommandation de ne pas s’intéresser à cette affection dans le cadre d’un examen médical périodique. *La qualité des résultats signalés dans les présentes directives cliniques a été établie conformément aux critères d’évaluation des résultats présentés dans le Rapport du groupe de travail canadien sur l’examen médical périodique. †Les recommandations que comprennent les présentes directives cliniques ont été classées conformément à la méthode de classification décrite dans le Rapport du groupe de travail canadien sur l’examen médical périodique. Guide de l’examen médical périodique – révision janvier 2010 | 69 American geriatrics society Class I: Evidence from At least one randomized controlled trial or meta-analysis of randomized controlled trials. Class II: Evidence from at least one controlled study without randomization or evidence or evidence from at least one other type of quasi experimental study. Class III: Evidence from non-experimental studies, such as comparative studies, correlation studies and case-controlled studies. Class IV: Evidence from expert committee reports or opinions and/or clinical experience of respected authorities. The strength of the recommendations is classified as follows: A. Directly based on Class I evidence. B. Directly based on Class II evidence or extrapolated recommendation from Class I evidence. C. Directly based on Class III evidence or extrapolated recommendation from Class I or II evidence. D. Directly based on Class IV evidence or extrapolated recommendation from Class I, II, or III evidence. AAFP: American Academy of Family Physicians SR: Strongly Recommend: Good quality evidence exists which demonstrates substantial net benefit over harm; the intervention is perceived to be cost effective and acceptable to nearly all patients. R: Recommend: Although evidence exists which demonstrates net benefit, either the benefit is only moderate in magnitude or the evidence supporting a substantial benefit is only fair. The intervention is perceived to be cost effective and acceptable to most patients. NR: No Recommendation Either For or Against: Either good or fair evidence exist of at least a small net benefit. Cost-effectiveness may not be known or patients may be divided about acceptability of the intervention. RA: Recommend Against: Good or fair evidence which demonstrates no net benefit over harm. I : Insufficient Evidence to Recommend Either for or Against: No evidence of even fair quality exists or the existing evidence is conflicting. I-HB: Healthy Behavior is identified as desirable but the effectiveness of physician's advice and counselling is uncertain. 70 | Umf de Gatineau ANNEXE 5 SCORE ORAI Guide de l’examen médical périodique – révision janvier 2010 | 71 72 | Umf de Gatineau TABLEAU DU GUIDE DE DÉPISTAGE DES ITSS Copié du guide québécois de dépistage des ITSS 2006 Guide de l’examen médical périodique – révision janvier 2010 | 73