6th Autophagy Scientific Days organized by CFATG BORDEAUX

6th Autophagy Scientific Days organized by CFATG
BORDEAUX – 2016 – CFATG6
Wednesday October 12th
13h30-15h00
Registration
15h00-15h15
Welcome address by CFATG president - Mathias Faure
and local committee coordinator – Nadine Camougrand
15h15-16h00
Keynote session I :
Dr Terje Johansen
(University of Tromso, Norway)
Title: TBA
16h00-16h30
Session I : REGULATION AND SIGNALING
Session Chairs : Muriel Priault (Institut de Biochimie et Génétique
cellulaires, UMR 5095, Bordeaux) ; Raul Duran (Group Metabolism and Cell
Signaling, IECB, U1218 INSERM, Bordeaux)
16h00-16h15
Amélie Bernard (University of Michigan, USA)
Identification and characterization of pathways controlling the
expression of ATG genes
16h15-16h30
Elise Jacquin (The Babraham Institute, UK)
"Cells, Drugs and Vacuoles": A story of non-canonical autophagy
16h30-17h00
Coffee Break
17h00-18h00
Session I : REGULATION AND SIGNALING
17h00-17h15
Céline Jenzer (I2BC, CNRS, Gif-sur-Yvette)
Determination of functional specificity of LC3 proteins during
phagocytosis of apoptotic cells in embryo
17h15-17h30
Virginie Hubert (Medical University of Vienna, Autriche)
LAMP-2 is required to incorporate syntaxin 17 into
autophagosome and mediate their fusion
17h30-17h45
Ghita Ghislat (Cambridge Institute for Medical Research,UK)
Annexins: new regulators of autophagic trafficking under starvation
17h45-18h00
Flash Talks Session I:
the
Session Chair : Sophie Pattingre (Institut de Recherche en Cancérologie
de Montpellier)
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18h00-21h00
Florian Beaumatin (Beatson institute for cancer research, Glasgow,
UK)
mTOR requires DRAM1 to sense amino acids
Ana Maria Negulescu (Centre Léon Bérard - Centre de recherche en
cancérologie, Lyon)
Kremen-1 receptor functions as a putative tumor suppressor in breast
cancer by inducing autophagic cell death in absence of its ligand
Dickkopf-1
Mouradi El Hout (Institut Necker-Enfants Malades, Université Paris V Paris Descartes, Paris)
Role of AUTOPHAGY in CANCER STEM CELLS: From cytoprotection to
metabolic reprogramming
Clément Mazouffre (Laboratoire Homéostasie Cellulaire et
Pathologies, Université de Limoges)
Survival in colorectal cancer: collaboration between BDNF/TrkB and
autophagy pathways
Welcome cocktail and
Poster Session I
Thursday October 13th
09h00-10h15
Session II : PATHOPHYSIOLOGY
Session
Chairs :
Benjamin
Dehay
(Institut
des
Maladies
Neurodégénératives CNRS UMR 5293 – Université de Bordeaux) ; Iban
Seiliez (UMR1419 INRA-UPPA NuMeA, St Pée sur Nivelle)
09h00-09h15
Carole Kretz-Remy (Institut NeuroMyoGène, Université Claude
Bernard- Lyon I, Villeurbanne)
NFKB is a master regulator of protein quality control in response to
protein aggregation stresses via autophagy modulation
09h15-09h30
Nicolas Charlet-Berguerand (Institut de Génétique et de Biologie
Moléculaire et Cellulaire, Université de Strasbourg)
The C9ORF72/ SMCR8 complex is a GDP/GTP exchange factor for
Rab GTPases and regulates autophagy
09h30-09h45
Hortense De Calbiac (Institut du Cerveau et de la Moelle épinière,
Paris)
C9ORF72 rescues the loss of function of the autophagy initiator
p62/SQSTM1
09h45-10h00
Jeanne Perez (Institut des Maladies Métaboliques et
Cardiovasculaires, Université Paul Sabatier, Toulouse)
Oxidative stress by monoamine oxidase-A impairs transcription
factor-EB activation and autophagosome clearance leading to
cardiomyocyte necrosis and heart failure
10h00-10h15
Marouane Kheloufi (Centre de Recherche Cardiovasculaire,
Université Paris Descartes, Paris)
Endothelial autophagy is required for atheroprotective signaling
10h15-10h45
Coffee Break
10h45-11h30
Keynote session II :
Dr Claudine Kraft
(University of Vienna, Austria)
EMBO Young Investigator Lecture
Title: Regulation and Signaling in Autophagy: Atg1/ULK1 Kinase
and Friends
11h30-11h45
Flash Talks Session II:
Session Chair : Sophie Pattingre (Institut de Recherche en Cancérologie
de Montpellier)
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11h45-14h30
Jana Alazzaz (INSERM U866, Université Bourgogne Franche-Comté ;
Dijon)
Resveratrol treatment controls Salmonella Typhimurium and adherentinvasive Escherichia coli persistence within intestinal epithelial cells
in an autophagy-dependent manner
Brieuc Perot (Institut Pasteur, Paris)
Autophagy represses the early interferon beta response to influenza A
virus, leading to a reduced interferon stimulated gene expression
following infection
Mickael Michaud (Institut Bergonié, Bordeaux)
Autophagy impacts the immune response to cancer treatments
Avédis Torossian (Centre de Recherche en Cancérologie de Toulouse,
Université Paul Sabatier, Toulouse)
Targeting Bcl-2 in ALK+ ALCL: at the crossroads between autophagy
and apoptotic cell death
Lunch and Poster Session II
14h30-15h15
Keynote session III :
Dr Kevin Ryan
(University of Glasgow, Scotland)
Title: Autophagy in cell death and cancer
15h15-16h00
Session III : CANCER
Session Chairs : Mojgan Djavaheri-Mergny (INSERM U1218, Institut
Bergonié, Bordeaux); Marion Bouchecareilh (UMR 5095, Institut de
Biochimie et Génétique cellulaires, Bordeaux)
15h15-15h30
Jean-Max Pasquet (U1035 INSERM, Université de Bordeaux)
Chronic myeloid leukemia progenitor cells require autophagy when
leaving hypoxia-induced quiescence
15h30-15h45
Magali Humbert (Institute of Pathology, Division of Experimental
Pathology, Berne, Switzerland)
P73-DAPK2-ATG5 Pathway in Acute Promyelocytic Leukemia
Therapy
15h45-16h00
Ada Nowosad (Centre de Recherche en Cancérologie de Toulouse,
Université Paul Sabatier, Toulouse)
Role of p27 in autophagy regulation in response to amino acid
deprivation
16h00-16h30
Coffee Break and Vote for best poster and for best flash talk
16h30-17h00
Session III : CANCER
16h30-16h45
Kelly Airiau (Institut Bergonié, Université de Bordeaux)
All-trans retinoic acid promotes p62 accumulation and potentiates
TRAIL-induced extrinsic apoptosis in acute promyelocytic leukemia
16h45-17h00
Aurélien Schwob (Centre International de Recherche en
Infectiologie, Ecole Normale Supérieure, Lyon)
HTLV1 Tax-induced NF-kB activation is regulated by selective
autophagy receptors at autophagic membranes
17h00-18h00
Annual General CFATG Meeting (CFATG Members only)
18h00-20h00
Free time
20h00
Gala Dinner
At “ Salons du Palais de la Bourse ” ►
Friday October 14th
09h00-10h15
Session IV : INFECTION & IMMUNITY
Session Chairs : Harald Wodrich (Laboratoire de microbiologie
Fondamentale et Pathogénicité, Université de Bordeaux) ; Frédéric Gros
(Institut de biologie moléculaire et cellulaire, Strasbourg)
09h00-09h15
Hoa Mai Nguyen (DIMNP-UMR 5235 CNRS, Université de Montpellier)
Important role of autophagy-related protein TgATG9 for parasite
survival in their host
09h15-09h30
Pauline Verlhac (Centre International de Recherche
Infectiologie, Université Claude Bernard - Lyon I, Lyon)
A new regulator of autophagosome maturation
09h30-09h45
Charlotte Montespan (Laboratoire de microbiologie Fondamentale
et Pathogénicité, Université de Bordeaux)
Adenoviruses control autophagy during cell entry through a
conserved PPxY motif
09h45-10h00
Florent Arbogast (Institut de biologie moléculaire et cellulaire,
Strasbourg)
ATG5 is required for the constitution of the immune synapse after B
cell receptor engagement, and for the subsequent presentation of
immobilized antigens
10h00-10h15
Amandine Serrano (Centre de biophysique moléculaire, Orléans)
During efficient Anti-RetroViral (ARV) therapy, the expression of
GALIG and its interacting partners involved in macroautophagy are
deregulated
10h15-10h45
Coffee Break & Vote for best short talk
10h45-11h15
Autophagy Network (COST)
Dr Caty Casas Louzao :
en
Chair of the COST Action: TRANSAUTOPHAGY
(Universitat autonoma de Barcelona, Spain)
11h15-11h45
Awards: best « short talk », best « poster » and best «flash talk »
12h00
End of meeting (Lunch Box before departure)