Hervé KEMPF CR1 INSERM UMR CNRS 7561-Université de

Hervé KEMPF CR1 INSERM UMR CNRS 7561-Université de

Hervé KEMPF
CR1 INSERM
UMR CNRS 7561-Université de Lorraine
Bâtiment Biopôle
9, Avenue de la Forêt de Haye
54500 Vandoeuvre-lès-Nancy
[email protected]
Interests
Molecular Mechanisms of Articular and Vascular Pathologic Mineralization
Signals and Transcription Factors Implicated in Embryonic Chondrogenesis
Career/Academic Appointments
Since 2011
Research fellow (CR1 INSERM), UMR CNRS 7561, Nancy, France
2007-2010
Research fellow (CR1 INSERM), INSERM U833, Collège de France, Paris, France
2005-2006
Instructor, Collège de France, Paris, France
2000-2005
Postdoctoral Fellow, Harvard Medical School, Boston, USA
1994-1999
Graduate Student, Collège de France, Paris, France
1994
Research Scientist, McGill University, Montréal, Canada
Professional Honors & Awards
2004-2005
Awardee of the The Arthritis Foundation (Massachusetts Chapter)
2001-2004
Awardee of the Human Frontier Science Organization
1999
Recipient of the "Young Researcher Price" from the Bettencourt-Schueller Foundation
Professionnal societies & Organizations
Since 2011
Société Française de Biologie des Tissus Minéralisés (SFBTM)
Since 2010
European Vascular Biology Organization (EVBO)
Since 2009
European Calcified Tissue Society (ECTS)
Since 2009
North American Vascular Biology Organization (NAVBO)
Since 2003
American Society for Bone and Mineral Research (ASBMR)
Since 1996
Society for Developmental Biology (SDB)
Selected Publications
M. Leroux-Berger, I. Queguiner, T.T Maciel, A. Ho, F. Relaix and H. Kempf. Pathologic mineralization of adult
vascular smooth muscle cells differs upon their crest or mesodermal embryonic origin. Journal of Bone and Mineral
Research, 26(7), 1543-1553, 2011.
C.N. Kamei, H. Kempf, R. Yelin, G. Daoud, R.G. James, A.B. Lassar, C.J. Tabin and T.M. Schultheiss. Promotion
of avian endothelial cell differentiation by GATA transcription factors. Developmental Biology, 353(1), 29-37, 2011.
T.T Maciel, H. Kempf and A.H. Campos. Targeting bone morphogenetic protein signaling on renal and vascular
diseases. Current Opinion in Nephrology and Hypertension,19(1), 26-31, 2010
H. Kempf, A. Ionescu, A.M. Udager and A.B. Lassar. Prochondrogenic signals induce a competence for Runx2 to
activate hypertrophic chondrocyte gene expression. Developmental Dynamics, 236,1954–1962, 2007.
H. Kempf*, S. Provot*, L.C. Murtaugh, U. Chung, D.W. Kim, J. Chyung, H. Kronenberg and A.B.
Lassar. Nkx3.2/Bapx1 is a negative regulator of chondrocyte maturation. Development, 133(4), 651-662, 2006.
*equal contribution.
E. Tzahor, H. Kempf, R.C. Mootoosamy, A.C. Poon, A. Abzhanov, C.J. Tabin, S. Dietrich and A.B. Lassar.
Antagonists of Wnt and BMP signaling induce the formation of vertebrate head muscle. Genes and Development,
17(24), 3087-3099, 2003.
L. Zeng, H. Kempf, L.C. Murtaugh, M.E. Sato and A.B. Lassar. Shh establishes an Nkx3.2/Sox9 autoregulatory loop
that is maintained by BMP signals to induce somitic chondrogenesis. Genes and Development, 16 (15), 19902005, 2002.
H. Kempf, C. Linares, P. Corvol and J.M. Gasc. Pharmacological inactivation of the endothelin type A receptor in
the early chick embryo : a model of mispatterning of the branchial arch derivatives. Development, 125, 24, 49314941, 1998.